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| 1 | Brown adipose tissue transplantation improves whole-body energy metabolism显示文摘 | Qingsheng Chi Dehua Wang Zhaoyun Zhang Chenzhong Li Yiming Li Yaoming Xue John R Speakma Wanzhu Jin Xiaomeng Liu Zongji Zhen Xiaoming Zhu Minghui Meng Lan Li Yanyan Shen | 2013 | Cell Research2013，23，6： | 11 |
| 2 | Theoretical Calculation of Dielectronic-Recombination Cross Section for Hydrogen-Like Argon显示文摘Dielectronic-recombination cross sections of hydrogen-like argon are calculated conveniently by our simplified relativistic configuration-interaction method.The results for the KLL,KLM,KLN,and KLO resonances are in good agreement with experimental measurement within a few percent.Our methods can provide various dielectronic-recombination rates which can satisfy the need for relevant applications. | WANG Jianguo ZOU Yu DONG Chenzhong LI Jiaming | 1995 | Chinese Physics Letters1995，12，9： | 3 |
| 3 | β-Cyclodextrin and Its Derivatives Functionalized Magnetic Nanoparticles for Targeting Delivery of Curcumin and Cell Imaging显示文摘 | Yehong Zhou Congli Wang Fei Wang Chenzhong Li Chuan Dong Shaomin Shuang | 2016 | Chinese Journal of Chemistry2016，34，6： | 2 |
| 4 | Phosphonium iodide as a donor liquid electrolyte for dye-sensitized solar cells显示文摘 | Li Hui Jiang Hongshi Yao Chenzhong | 2011 | Journal of serbian chemical society2011，76，5： | 1 |
| 5 | Multi-Scale PIIFD for Registration of Multi-Source Remote Sensing Images显示文摘This paper aims at providing multi-source remote sensing images registered in geometric space for image fusion.Focusing on the characteristics and differences of multi-source remote sensing images,a feature-based registration algorithm is implemented.The key technologies include image scale-space for implementing multi-scale properties,Harris corner detection for keypoints extraction,and partial intensity invariant feature descriptor(PIIFD)for keypoints description.Eventually,a multi-scale Harris-PIIFD image registration algorithm framework is proposed.The experimental results of fifteen sets of representative real data show that the algorithm has excellent,stable performance in multi-source remote sensing image registration,and can achieve accurate spatial alignment,which has strong practical application value and certain generalization ability. | Chenzhong Gao Wei Li | 2021 | Journal of Beijing Institute of Technology2021，30，2： | 1 |
| 6 | 三维微小凹图式的制备及其与C17.2神经干细胞的复合显示文摘以紫外光光刻及氢氟酸湿法蚀刻加工硅阳模,采用基于聚二甲基硅氧烷(PDMS)的软光刻技术制备9种不同结构尺寸的聚乳酸-羟基乙酸共聚物(PLGA)和PMDS三维微小凹图式。PLGA及PDMS三维微小凹图式经等离子氧蚀刻和多聚赖氨酸裱衬处理后进行C17.2神经干细胞培养。随着在图式上培养时细胞的增殖,C17.2神经干细胞逐渐在微小凹中聚集,表现出明显的三维生长行为;通过羧基荧光素乙酰乙酸琥珀酰亚胺酯(CFDA-SE)染色后进行激光共聚焦显微扫描与三维重构,显示大部分细胞生长于微小凹中离底面30~90μm的区间内;免疫荧光结果显示C17.2神经干细胞在三维微结构中复合培养2d后呈现均一的巢蛋白(Nestin)阳性。结论:本文设计的微小凹图式适用于C17.2神经干细胞的三维培养及后续的分化研究,细胞于微小凹图式培养过程中可以保持均一的干细胞特性。 | 张利光 吴泽志 宋兆全 黄岂平 廖彦剑 Li Chenzhong | 2012 | 生物医学工程学杂志2012，29，3： | 1 |
| 7 | SARS-CoV-2 Epitopes following Infection and Vaccination Overlap Known Neutralizing Antibody Sites显示文摘Identification of epitopes targeted following virus infection or vaccination can guide vaccine design and development of therapeutic interventions targeting functional sites,but can be laborious.Herein,we employed peptide microarrays to map linear peptide epitopes(LPEs)recognized following SARS-CoV-2 infetion and vaccination.LPEs detected by nonhuman primate(NHP)and patient IgMs after SARS-CoV-2 infection extensively overlapped,localized to functionally important virus regions,and aligned with reported neutralizing antibody binding sies.Similar LPE overlap occurred atfter infection and vaccination,with LPE clusters specifc to each stimulus,where strong and conserved LPEs mapping to sites known or likely to inhibit spike protein function.Vaccine-specifc LPEs tended to map to sites known or likely to be afected by structural changes induced by the proline substitutions in the mRNA vaccine's S protein.Mapping LPEs to regions of known functional importance in this manner may acelerate vaccine evaluation and discovery of targets for sile secific therapeutic interventions. | Li Yang Te Liang Lane M.Pierson Hongye Wang Jesse K.Fletcher Shu Wang Duran Bao Lii Zhang Zhen Huang Wenshu Zheng Xiaomei Zhang Heewon Park Yuwen Li James E.Robinson Amy K.Fechan Christopher J.Lyon Jing Cao Lisa A.Morici Chenzhong Li Chad J.Roy Xiaobo Yu Tony Hu | 2022 | Research2022，，2： | 0 |
| 8 | 4-1 Dielectronic Recombination of 36Ar15+ and 112Sn34+ at the CSRm显示文摘The total recombination rate coefficients of lithium-like 36Ar15+ ions have been measured by employing the electron-ion merged-beams technique at the heavy ion storage ring CSRm at IMP[1]. Fig. 1 (a) shows the DR spectrum for electron energy from 0 to 35 eV in the center-of-mass (c.m.) frame involving all the DR resonances associated with 2s1=2!2p1=2 and 2s1=2!2p3=2 excitations. | Huang Zhongkui Ma Xinwen Wen Weiqiang Wang Hanbing Chuai Xiaoya Dou Lijun Zhu Xiaolong Xu Xin Zhu Linfan Xu Weiqing Mao Lijun Li Jie Zhang Xiaohu Ma Xiaoming Yan Tailai Yang Jiancheng Yuan Youjin Xiao Guoqing Xia Jiawen Xie Luyou Dong Chenzhong DR collaboration | 2015 | IMP & HIRFL Annual Report2015，，1： | 0 |
| 9 | Joint Toxicity Determination of Clopyralid,Picloram and Benazolin Mixtures on Broad-leaved Weed Lapsana apogonoides Maxim.in Rape Fields显示文摘[Objectives]This study was conducted to investigate the compounding of three herbicides:clopyralid,picloram and benazolin,so as to improve the effectiveness of herbicides.[Methods]With Lapsana apogonoides Maxim.as the target and clopyralid,picloram and benazolin as the test agents,seven gradient concentrations were set up to determine the joint toxicity of the three agents.[Results]When the compounding ratio of picloram,clopyralid and benazolin was 2∶1∶6,the maximum co-toxicity coefficient was 290.0.[Conclusions]The compounding of picloram,clopyralid and benazolin has a significant synergistic effect on L.apogonoides,which reduces production costs and environmental pressure,providing technical support for the effective control of broad-leaved weeds such as L.apogonoides. | Xiong LI Jingbo LI Huifang DENG Yunyun ZHOU Kaifa GUO Xiongmei ZHU Chenzhong JIN Guiying LIU | 2021 | Agricultural Biotechnology2021，10，5： | 0 |
| 10 | Biological evaluation of 2-methylpyrimidine derivatives as active pan Bcr-Abl inhibitors显示文摘We designed a series of 2-methylpyrimidine derivatives as new BCR-ABL inhibitors using scaffold-hopping strategy.These synthetic compounds exhibited significant inhibition against a broad spectrum of Bcr-Abl mutants including the gatekeeper T315I mutant.Compound 7u showed very potent kinase inhibitory activities against Bcr-Abl WT,Bcr-Abl E255K,Bcr-Abl Q252H,Bcr-Abl G250E and Bcr-Abl T315I,with IC50 values of 0.13 nM,0.17 nM,0.24 nM,0.19 nM and 0.65μM,respectively.This compound also displayed anti-proliferation activity against K562 cell line with an IC50 value of 1.1 nM,thus representing a new lead for further optimization. | ZOU DingBiao QIU YaTao TU ZhengChao LIAO ChenZhong LUO JinFeng MENG QingQing YAO RiSheng LI Zheng JIANG Sheng | 2014 | Science China Chemistry2014，57，6： | 0 |
| 11 | Study on the Optimization of Extraction Technology of Rose laevigate Michx. Polysaccharides and Its in vitro Antioxidant Activity显示文摘[Objectives]This study was conducted to optimize the optimal process conditions for extracting polysaccharides from Rose laevigate Michx.with hot water.[Methods]The extraction rate of R.laevigate was used as an evaluation index,and extraction temperature,material-to-liquid ratio,extraction time and extraction times were selected as influencing factors.On the basis of single factor tests,L 9(34)orthogonal tests were carried out for optimization,and the content of polysaccharides was determined by the phenol-sulfuric acid method.The in vitro antioxidant activity of the extracted R.laevigate polysaccharides was studied.[Results]The effects of various influencing factors on the extraction rate of R.laevigate polysaccharides ranked as material-liquid ratio>extraction temperature>extraction times>extraction time.The optimal extraction process was extraction temperature 80℃,extraction time 2 h,and material-to-liquid ratio 1∶25,extraction times 3 times,under which the extraction rate was(9.55±0.12)%.R.laevigate polysaccharides had certain scavenging capacities of DPPH free radicals and hydroxyl free radicals,and its scavenging capacity of DPPH free radicals was better than that of hydroxyl free radicals.[Conclusions]This study provides a theoretical basis for the optimization of the extraction process of R.laevigate polysaccharides and the in-depth development and application of polysaccharides. | Guochen HU Han LIU Qianqian TANG Li CHENG Chenzhong JIN Yunyun ZHOU Xuejiao ZHANG Guiying LIU | 2021 | Agricultural Biotechnology2021，10，6： | 0 |
| 12 | Effects of Abscisic Acid on Cold Resistance in Digitaria sanguinalis(L.)Scop.显示文摘[Objectives]This study was conducted to detect the protective effect of abscisic acid on chilling injury of Digitaria sanguinalis(L.)Scop,and whether this effect is related to antioxidant enzymes and osmotic adjustment.[Methods]D.sanguinalis plants were sprayed with abscisic acid solution,and exposed to cold stress at 15℃for 3 d after one day and then at 5℃for 25 to 30 d in a growth chamber.The changes of plant osmotic potential under this treatment were detected.[Results]Under low temperature stress,the osmotic potential of plants in the abscisic acid treatment and the control increased,but the osmotic potential level of the abscisic acid treatment plants was lower.The SOD activity of plants in the ABA treatment and the control decreased under low temperature stress.Under low temperature stress,the activity of catalase and peroxidase in ABA-treated plants was higher than that in control plants.[Conclusions]This study provides a theoretical basis for the impact of abscisic acid on the physiological response of D.sanguinalis to cold injury. | Rongbo ZHOU Yihong HU Li ZHOU Jie PENG Fan XIE Chenzhong JIN | 2024 | Agricultural Biotechnology2024，13，1： | 0 |
| 13 | Study on the Resistance Levels of Different Echinochloa crusgalli Populations to Penoxsulam and Bispyribac-sodium显示文摘[Objectives]This study was conducted to screen the resistance of Echinochloa crusgalli in some paddy fields in Changde City,Yiyang City and Yueyang City in Hunan Province to penoxsulam and bispyribac-sodium.[Methods]The resistance to penoxsulam and bispyribac-sodium was screened in 11 E.crusgalli populations collected from rice production areas in Changde,Yiyang and Yueyang Cities,Hunan Province,and the resistance level of population HU-2 to penoxsulam was determined.[Results]HU-1 to HU-6 and HU-8 A,a total of seven populations showed high levels of resistance to penoxsulam and bispyribac-sodium.The resistance level of population HU-2 to penoxsulam was extremely high;population HU-7 showed low-level resistance to both drugs;HU-11 population showed low-level resistance to penoxsulam and was susceptible to bispyribac-sodium;and populations HU-8 and HU-9 were susceptible to penoxsulam and bispyribac-sodium.[Conclusions]This study provides a technical basis for the rational use of penoxsulam and bispyribac-sodium and the selection of control chemicals for E.crusgalli in paddy fields. | Qi LEI Bingjie LIU Jingbo LI Yunyun ZHOU Kailing PENG Chenzhong JIN Xiu LIU Kaifa GUO Guiying LIU | 2022 | Agricultural Biotechnology2022，11，4： | 0 |
| 14 | 4 - 9 Dielectronic Recombination Experiment of 78Kr28+ on HIRFL-CSRm显示文摘 | Huang Zhongkui Ma Xinwen Wen Weiqiang Wang Hanbing Xu Weiqing Zhu Xiaolong Gao Yong Zhao Dongmei Cheng Xiaowei Yang Xiaodong Li jie Ma Xiaoming Yan Tailai Yang Jiancheng Mao Lijun Xia Jiawen Yuan Youjin Xu Hushan Xiao Guoqing Xu Xin ZhuLinfan ShiYinglong Dong Chenzhong | 2013 | IMP & HIRFL Annual Report2013，，1： | 0 |
| 15 | Effects of Ethanol Condensation Reflux Extraction and Ultrasound-assisted Extraction on the Content of Total Flavonoids of Pueraria edulis显示文摘With Pueraria edulis from different habitats in Yunnan Province,Guangdong Province and Guangxi Zhuang autonomous region as materials,the medicinal materials of P.edulis were extracted by ethanol condensation reflux extraction and ultrasound-assisted extraction,and the effects of different extraction methods the contents of total flavonoids in P.edulis from different areas were compared.The results showed that the best extraction time for P.edulis in Yunnan Province was 20 min,and that for Guangdong and Guangxi Zhuang Autonomous Region was 30 min.The yield of total flavonoids from P.edulis extracted by the condensation reflux extraction method was relatively better.The content of total flavonoids in P.edulis in Yunnan was the highest with an average content of 0.2557%,while the average content of total flavonoids in P.edulis in Guangdong was the lowest with an average content of 0.2108%. | Jun TANG Jianguang ZENG Hao LI Chenzhong JIN | 2023 | Agricultural Biotechnology2023，12，2： | 0 |
| 16 | Target Resistance of Eleusine indica to Glyphosate显示文摘[Objectives]This study was conducted to detect the evolution of resistance to glyphosate in Eleusine indica.[Methods]In the previous study,glyphosate-resistant population T2-4 was screened out from E.indica populations in sugarcane fields in Guangxi.In this study,we determined the resistance index of T2-4 by whole plant bioactivity assay and further explored the molecular biological mechanism of resistance.[Results]The resistance index of T2-4 was 112,and it is thus a highly resistant population.Amino acid mutations were found at positions 102,106 and 381 in the EPSPS sequence of T2-4,containing at least a triple mutation allele in Thr-102-Ile,Pro-106-Ser and Pro-381-Leu and a double mutation allele in Pro-106-Ser and Pro-381-Leu.qPCR was used to determine the EPSPS gene copy number and expression in resistant plants of T2-4.EPSPS gene copy number and expression both increased,with 8.3-fold higher copy number and 2.7-fold higher expression than the sensitive population.Therefore,the resistance of T2-4 to glyphosate was mainly caused by multiple target mechanisms including mutation of EPSPS gene,copy number increase and expression increase,and the resistance of E.indica to glyphosate needs our high attention.[Conclusions]At present,the level of resistance to glyphosate is very high in the sugarcane fields of Guangxi,and it is necessary to take a variety of weed control measures to solve the problem of glyphosate resistance. | Tao ZHANG Siquan LUO Lingli BAI Hongyuan KUANG Chenzhong JIN Yanhui WANG Jingbo LI Bin SUN Zijuan DING | 2022 | Agricultural Biotechnology2022，11，6： | 0 |
| 17 | Effects of Polygonatum sibiricum Polysaccharide (PSP) on Inflammatory Factors in Rats Fed on High-fat Diet显示文摘[Objectives]This study was conducted to explore the effects of Polygonatum sibiricum polysaccharide(PSP)on chronic intestinal inflammation caused by high-fat diet.[Methods]Thirty five male healthy SD rats were randomly divided into a normal control group(NC,normal diet,n=10)and a high-fat diet group(HF,high-fat diet,n=25).After 8 weeks,an obesity model was established.The HF group was randomly divided into an HF group and a PSP treatment group[PSP,300 mg/(kg·d)].After 6 weeks of intervention with PSP,rat serum was collected,and the spleen and thymus were stripped,and weighed.Serum IgG,IgM,LPS and IL-1βand IL-6 contents were detected by ELISA,and HE staining was adopted to observe the pathological changes of the colon tissue.[Results]PSP reduced the level of LPS caused by high-fat diet and the levels of inflammatory factors IL-6 and TNF-α,increased the indexes of the thymus and spleen serving as immune organs,increased IgG and IgM contents,and alleviated pathological damage to the colon tissue caused by high-fat diet.[Conclusions]This study provides a theoretical basis and experimental basis for the development of drugs for treating metabolic diseases such as obesity and inflammation. | Mingzhe SU Mingjun LI Lingli BAI Chenzhong JIN Yihong HU Yan WANG | 2023 | Agricultural Biotechnology2023，12，4： | 0 |
| 18 | Effects of Polygonatum sibiricum Polysaccharide on Antioxidant Capacity of the Liver in High-fat Diet Rats显示文摘[Objectives]This study was conducted to investigate the effects of Polygonatum sibiricum polysaccharide(PSP)on antioxidant function in high-fat diet obese rats.[Methods]Thirty five healthy male SD rats were selected to establish an obesity model after feeding a high-fat for 8 weeks.They were then randomly divided into a normal group(NC),a high-fat diet group(HF),and an HF+P.sibiricum polysaccharide group[HF+PSP,300 mg/(kg·d)].After 6 weeks of PSP intervention,the serum and liver of rats were collected,and the activity of aspartate transaminase(AST)and alanine aminotransferase(ALT)in serum,the enzyme activity of superoxide dismutase(SOD),catalase(CAT)and glutathione peroxidase(GSH-Px)and malondialdehyde(MDA)in liver tissue were measured.The pathological changes of liver tissue were observed by HE staining.[Results]Compared with the HF group,PSP could effectively inhibit obesity caused by high-fat diet.It reduced body weight and serum AST and ALT levels,increased the contents of T-SOD,CAT and GSH-Px in the liver,and inhibited the accumulation of MDA content,thereby reducing damage to liver cells caused by a high-fat diet.It indicated that PSP could effectively inhibit obesity in high-fat diet rats and enhance their antioxidant capacity.[Conclusions]This study provides a reference for the study of the antioxidant capacity of PSP. | Heyi GONG Zhifeng LI Chenzhong JIN Yihong HU Yan WANG | 2023 | Agricultural Biotechnology2023，12，4： | 0 |
| 19 | Effects of Polygonatum odoratum Polysaccharides on the Quality of White Chili Peppers in Jars显示文摘[Objectives]This study was conducted to investigate the effects of Polygonatum odoratum polysaccharides on the quality of white chili peppers in jars.[Methods]White chili peppers were pickled by adding different concentrations of P.odoratum polysaccharides with traditional pickling technology,and its nitrite content,pH and sensory quality were analyzed and detected.[Results]The results showed that,compared with the control group without adding P.odoratum polysaccharides,the nitrite content in white chili peppers in jars decreased after adding P.odoratum polysaccharides.When the addition amount of P.odoratum polysaccharides was 0.002%,the inhibition rate of nitrite reached the maximum.Under the same fermentation time,P.odoratum polysaccharides could significantly reduce the pH value of pickles.When the addition amount of P.odoratum polysaccharide was 0.002%and the pickling time was 3 months,the sensory quality of white chili peppers in jars was the best.At this point,white chili peppers in jars had rich aroma and tasted soft and sour,and the sour and salinity were suitable.As the fermentation time continued to increase,the chili aroma of white chili peppers in jars gradually decreased,and the sour taste became more pronounced.[Conclusions]This study can provide reference for the safety and quality control of white chili peppers in jars. | Xiuqiang WANG Li ZHOU Chenzhong JIN Yihong HU Jing QIU Yunyun ZHOU Yan WANG | 2023 | Agricultural Biotechnology2023，12，4： | 0 |
| 20 | 基于荧光等技术构建适体传感方法研究显示文摘生物标志物和食品污染物检测方法的发展,对于人类身体健康具有重要意义.荧光分析法因其灵敏度高得到广泛应用,但是在针对某一特定物质检测时特异性不高.另外,荧光检测体系中必须有荧光物质参与,但是能发荧光的基团种类不多. | 无 岳巧丽 刘继锋 王蕾 李海波 徐树玲 王怀生 Chenzhong Li | 2023 | 中国科技成果2023，24，19： | 0 |
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