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| 1 | Indications and surgical options for small bowel, large bowel and perianal Crohn's disease显示文摘Despite advancements in medical therapy of Crohn's disease(CD), majority of patients with CD will eventually require surgical intervention, with at least a third of patients requiring multiple surgeries. It is important to understand the role and timing of surgery, with the goals of therapy to reduce the need for surgery without increasing the odds of emergency surgery and its associated morbidity, as well as to limit surgical recurrence and avoid intestinal failure. The profile of CD patients requiring surgical intervention has changed over the decades with improvements in medical therapy with immunomodulators and biological agents. The most common indication for surgery is obstruction from stricturing disease, followed by abscesses and fistulae. The risk of gastrointestinal bleeding in CD is high but the likelihood of needing surgery for bleeding is low. Most major gastrointestinal bleeding episodes resolve spontaneously, albeit the risk of re-bleeding is high. The risk of colorectal cancer associated with CD is low. While current surgical guidelines recommend a total proctocolectomy for colorectal cancer associated with CD, subtotal colectomy or segmental colectomy with endoscopic surveillance may be a reasonable option. Approximately 20%-40% of CD patients will need perianal surgery during their lifetime. This review assesses the practice parameters and guidelines in the surgical management of CD, with a focus on the indications for surgery in CD(and when not to operate), and a critical evaluation of the timing and surgical options available to improve outcomes and reduce recurrence rates. | James WT Toh Peter Stewart Matthew JFX Rickard Rupert Leong Nelson Wang Christopher J Young | 2016 | World Journal of Gastroenterology2016，22，40： | 2 |
| 2 | Factors Determining Diagnostic Yield of Endoscopic Ultrasound Guided Fine-Needle Aspiration for Pancreatic Cystic Lesions: A Multicentre Asian Study显示文摘 | Lee Guan Lim Sandeep Lakhtakia Tiing Leong Ang Charles K. F. Vu Frederick Dy Vui Heng Chong Christopher J. L. Khor Wee Chian Lim Bhavesh Kishor Doshi Shyam Varadarajulu Kenjiro Yasuda Jennie Y. Y. Wong Yiong Huak Chan Min En Nga Khek Yu Ho | 2013 | Digestive Diseases and Sciences2013，，6： | 2 |
| 3 | Long-term follow-up of initially successful trabeculectomy with 5-fluorouracil injections 1 1 The authors have no proprietary interest in any of the materials used in this study.显示文摘 | Ricardo Suzuki Christopher J Dickens Andrew G Iwach H.Dunbar Hoskins John Hetherington Richard P Juster Patricia C Wong Martha T Klufas Clifford J Leong Ngoc Nguyen | 2002 | Ophthalmology2002，，10： | 1 |
| 4 | A Large-Scale Genetic Association Study Confirms IL12B and Leads to the Identification of IL23R as Psoriasis-Risk Genes显示文摘 | Michele Cargill Steven J. Schrodi Monica Chang Veronica E. Garcia Rhonda Brandon Kristina P. Callis Nori Matsunami Kristin G. Ardlie Daniel Civello Joseph J. Catanese Diane U. Leong Jackie M. Panko Linda B. McAllister Christopher B. Hansen Jason Papenfuss | 2006 | The American Journal of Human Genetics2006，，： | 1 |
| 5 | Mid-Region Pro-Hormone Markers for Diagnosis and Prognosis in Acute Dyspnea显示文摘 | Alan Maisel Christian Mueller Richard Nowak W. Frank Peacock Judd W. Landsberg Piotr Ponikowski Martin Mockel Christopher Hogan Alan H.B. Wu Mark Richards Paul Clopton Gerasimos S. Filippatos Salvatore Di Somma Inder Anand Leong Ng Lori B. Daniels Sean-Xa | 2010 | Journal of the American College of Cardiology2010，，19： | 1 |
| 6 | Pericardial Fat Is Associated With Atrial Fibrillation Severity and Ablation Outcome显示文摘 | Christopher X. Wong Hany S. Abed Payman Molaee Adam J. Nelson Anthony G. Brooks Gautam Sharma Darryl P. Leong Dennis H. Lau Melissa E. Middeldorp Kurt C. Roberts-Thomson Gary A. Wittert Walter P. Abhayaratna Stephen G. Worthley Prashanthan Sanders | 2011 | Journal of the American College of Cardiology2011，，17： | 1 |
| 7 | Imaging volumes during COVID-19:A Victorian health service experience显示文摘BACKGROUND The World Health Organisation declared the coronavirus disease 2019(COVID-19)a pandemic on March 11,2020.While globally,the relative caseload has been high,Australia’s has been relatively low.During the pandemic,radiology services have seen significant changes in workflow across modalities and a reduction in imaging volumes.AIM To investigate differences in modality imaging volumes during the COVID-19 pandemic across a large Victorian public health network.METHODS A retrospective analysis from January 2019 to December 2020 compared imaging volumes across two periods corresponding to the pandemic’s first and second waves.Weekly volumes across patient class,modality and mobile imaging were summed for periods:wave 1(weeks 11 to 16 for 2019;weeks 63 to 68 for 2020)and wave 2(weeks 28 to 43 for 2019;weeks 80 to 95 for 2020).Microsoft Power Business Intelligence linked to the radiology information system was used to mine all completed examinations.RESULTS Summed weekly data during the pandemic’s first wave showed the greatest decrease of 29.8%in adult outpatient imaging volumes and 46.3%in paediatric emergency department imaging volumes.Adult nuclear medicine demonstrated the greatest decrease of 37.1%for the same period.Paediatric nuclear medicine showed the greatest decrease of 47.8%,with angiography increasing by 50%.The pandemic’s second wave demonstrated the greatest decrease of 23.5%in adult outpatient imaging volumes,with an increase of 18.2%in inpatient imaging volumes.The greatest decrease was 28.5%in paediatric emergency department imaging volumes.Nuclear medicine showed the greatest decrease of 37.1%for the same period.Paediatric nuclear medicine showed the greatest decrease of 36.7%.Mobile imaging utilisation increased between 57.8%and 135.1%during the first and second waves.A strong correlation was observed between mobile and nonmobile imaging in the emergency setting(Spearman’s correlation coefficient=-0.743,P=0.000).No correlation was observed in the inpatient setting(Spearman’s correlation coefficient=-0.059,P=0.554).CONCLUSION Nuclear medicine was most impacted,while computed tomography and angiography were the least affected by the pandemic.The impact was less during the pandemic’s second wave.Mobile imaging shows continuous growth during both waves. | Jo-Anne Pinson My Linh Diep Vinay Krishnan Caroline Aird Cassie Cooper Christopher Leong Jeff Chen Nicholas Ardley Eldho Paul Mohamed Khaldoun Badawy | 2022 | World Journal of Radiology2022，14，8： | 0 |
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