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| 1 | Regional features of the temperature trend in China based on Empirical Mode Decomposition显示文摘由实验模式分解方法,我们在超过 700 个车站分析了观察每月平均的温度从 1951 2001 在中国上。同时,每个车站的温度可变性被这个方法计算。 | SUN Xian LIN Zhenshan CHENG Xiaoxia JIANG Chuangye | 2008 | Journal of Geographical Sciences2008，18，2： | 8 |
| 2 | Estimating Soil Salinity in the Yellow River Delta, Eastern China——An Integrated Approach Using Spectral and Terrain Indices with the Generalized Additive Model显示文摘Soil salinity is one of the most severe environmental problems worldwide. It is necessary to develop a soil-salinity-estimation model to project the spatial distribution of soil salinity. The aims of this study were to use remote sensed images and digital elevation model(DEM) to develop quantitative models for estimating soil salinity and to investigate the influence of vegetation on soil salinity estimation. Digital bands of Landsat Thematic Mapper(TM) images, vegetation indices, and terrain indices were selected as predictive variables for the estimation. The generalized additive model(GAM) was used to analyze the quantitative relationship between soil salt content, spectral properties, and terrain indices. Akaike's information criterion(AIC) was used to select relevant predictive variables for fitted GAMs. A correlation analysis and root mean square error between predicted and observed soil salt contents were used to validate the fitted GAMs. A high ratio of explained deviance suggests that an integrated approach using spectral and terrain indices with GAM was practical and efficient for estimating soil salinity. The performance of the fitted GAMs varied with changes in vegetation cover.Salinity in sparsely vegetated areas was estimated better than in densely vegetated areas. Visible red and near-infrared bands, and the second and third components of the tasseled cap transformation were the most important spectral variables for the estimation. Variable combinations in the fitted GAMs and their contribution varied with changes in vegetation cover. The contribution of terrain indices was smaller than that of spectral indices, possibly due to the low spatial resolution of DEM. This research may provide some beneficial references for regional soil salinity estimation. | SONG Chuangye REN Hongxu HUANG Chong | 2016 | Pedosphere2016，26，5： | 6 |
| 3 | Transjugular intrahepatic portosystemic shunt for portal vein thrombosis with symptomatic portal hypertension in liver cirrhosis显示文摘 | Guohong Han Xingshun Qi Chuangye He Zhanxin Yin Jianhong Wang Jielai Xia Zhiping Yang Ming Bai Xiangjie Meng Jing Niu Kaichun Wu Daiming Fan | 2010 | Journal of Hepatology2010，，： | 5 |
| 4 | Predictive Vegetation Mapping Approach Based on Spectral Data, DEM and Generalized Additive Models显示文摘This study aims to provide a predictive vegetation mapping approach based on the spectral data, DEM and Generalized Additive Models (GAMs). GAMs were used as a prediction tool to describe the relationship between vegetation and environmental variables, as well as spectral variables. Based on the fitted GAMs model, probability map of species occurrence was generated and then vegetation type of each grid was defined according to the probability of species occurrence. Deviance analysis was employed to test the goodness of curve fitting and drop contribution calculation was used to evaluate the contribution of each predictor in the fitted GAMs models. Area under curve (AUC) of Receiver Operating Characteristic (ROC) curve was employed to assess the results maps of probability. The results showed that: 1) AUC values of the fitted GAMs models are very high which proves that integrating spectral data and environmental variables based on the GAMs is a feasible way to map the vegetation. 2) Prediction accuracy varies with plant community, and community with dense cover is better predicted than sparse plant community. 3) Both spectral variables and environmental variables play an important role in mapping the vegetation. However, the contribution of the same predictor in the GAMs models for different plant communities is different. 4) Insufficient resolution of spectral data, environmental data and confounding effects of land use and other variables which are not closely related to the environmental conditions are the major causes of imprecision. | SONG Chuangye HUANG Chong LIU Huiming | 2013 | Chinese Geographical Science2013，23，3： | 5 |
| 5 | Structure of the human activated spliceosome in three conformational states显示文摘在拼接的 pre-mRNA 的每个周期期间, pre 催化的 spliceosome (B 建筑群) 被变换成激活的 spliceosome (B 行为 建筑群) ,它有一个合法活跃地点但是不能继续到分叉的反应。这里,我们在场人的 B 处于三个不同 conformational 状态的行为 建筑群。他们地图允许将近所有的原子建模 U2 小原子 ribonucleoprotein (snRNP ) 的蛋白质部件,包括三 SF3a 建筑群和七 SF3b 建筑群。人的 B 行为 建筑群包含 52 蛋白质, U2, U5,和 U6 小原子 RNA (snRNA ) ,和 pre-mRNA。三不同符合构造被捕获了,代表人的 B 行为 建筑群。这些建筑群在开关环的取向不同 Prp8,拼接的因素 RNF113A 和 NY-CO-10,和十九建筑群(NTC ) 和 NTC 相关的建筑群的大多数部件。有 B 和 C 建筑群的这三建筑群和比较的分析在 B-to-B 行为 和 B 行为 -to-B* 转移,它最终为分叉的反应告知活跃地点。 | Xiaofeng Zhang, Chuangye Yan, Xiechao Zhan, Lijia Li, Jianlin Lei, Yigong Shi Jianlin Lei Yigong Shi | 2018 | Cell Research2018，28，3： | 4 |
| 6 | Dramatic transition between electric and magnetic rotations in ^(106)Ag显示文摘The lifetimes for the states of magnetic dipole band in106Ag have been measured using the Doppler-shift attenuation method via the reaction of100Mo(11B,5n)106Ag at a beam energy of 60 MeV.The reduced transition strengths of the magnetic dipole band,the B(M1)/B(E2)ratios together with the signature of the level energy as a function of angular momentum for the positive parity states of106Ag show that a drastic change of excitation mode,that is,from electric rotation to magnetic rotation,occurs within one unit of spin at around Iπ=12+.Theoretical calculations based on the triaxial projected shell model consistently reproduce the experimental data and provide an explanation on the nature of observed phenomena such that the dynamical drift of the rotational axis suddenly from the principal axis to the tilted one,along the positive parity bands of106Ag. | ZHENG Yun ZHU LiHua CHEN YongShou WU XiaoGuang HE ChuangYe HAO Xin LIU Ying WANG ZhiMin LI XueQin LI GuangSheng GAO ZaoChun SUN HuiBin | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，9： | 4 |
| 7 | Molecular architecture of the luminal ring of the Xenopus laevis nuclear pore complex显示文摘The nuclear pore complex(NPC)mediates the flow of substances between the nucleus and cytoplasm in eukaryotic cells.Here we report the cryo-electron tomography(cryo-ET)structure of the luminal ring(LR)of the NPC from Xenopus laevis oocyte.The observed key structural features of the LR are independently confirmed by single-particle cryo-electron microscopy(cryo-EM)analysis.The LR comprises eight butterfly-shaped subunits,each containing two symmetric wings.Each wing consists of four elongated,tubular protomers.Within the LR subunit,the eight protomers form a Finger domain,which directly contacts the fusion between the inner and outer nuclear membranes and a Grid domain,which serves as a rigid base for the Finger domain.Two neighboring LR subunits interact with each other through the lateral edges of their wings to constitute a Bumper domain,which displays two major conformations and appears to cushion neighboring NPCs.Our study reveals previously unknown features of the LR and potentially explains the elastic property of the NPC. | Yanqing Zhang Sai Li Chao Zeng Gaoxingyu Huang Xuechen Zhu Qifan Wang Kunpeng Wang Qiang Zhou Chuangye Yan Wusheng Zhang Guangwen Yang Minhao Liu Qinghua Tao Jianlin Lei Yigong Shi | 2020 | Cell Research2020，30，6： | 4 |
| 8 | Structures of the human pre-catalytic spliceosome and its precursor spliceosome显示文摘The pre-catalytic spliceosome (B complex) is preceded by its precursor spliceosome (pre-B complex) and followed by the activated spliceosome (Bact complex). The pre-B-to-B and B-to-Bact transitions are driven by the ATPase/helicases Prp28 and Brr2,respectively. In this study,we report the cryo-electron microscopy structures of the human pre-B complex and the human B complex at an average resolution of 5.7 and 3.8 A,respectively. In the pre-B complex,U1 and U2 small nuclear ribonucleoproteins (snRNPs) associate with two edges of the tetrahedron-shaped U4/U6.U5 tri-snRNP. The pre-mRNA is yet to be recognized by U5 or U6 small nuclear RNA (snRNA),and loop I of U5 snRNA remains unengaged. In the B complex,U1 snRNP and Prp28 are dissociated,the 5’-exon is anchored to loop I of U5 snRNA,and the 5’-splice site is recognized by U6 snRNA through duplex formation. In sharp contrast to S. cerevisiae,most components of U2 snRNP and tri-snRNP,exemplified by Brr2,undergo pronounced rearrangements in the human pre-B-to-B transition. Structural analysis reveals mechanistic insights into the assembly and activation of the human spliceosome. | Xiechao Zhan Chuangye Yan Xiaofeng Zhang Jianlin Lei Yigong Shi | 2018 | Cell Research2018，28，12： | 4 |
| 9 | Revisiting the TALE repeat显示文摘抄写像使活跃之物(TAL ) 受动器明确地绑加倍搁浅(ds ) 通过双人脚踏车的一个中央领域的 DNA 重复。每次 TAL 受动器(故事) 重复包括 3335 氨基酸并且在重复在一个固定位置通过高度可变的残余认出一个特定的 DNA 库。结构的研究由故事重复揭示了 DNA 识别的分子的基础。全面结构的检查表明故事蛋白质的基本积木,也就是一个螺旋状的发卡,一个螺旋从以前定义的故事主题被转移。这里,我们希望建议以绑在 DNA 脊梁磷酸盐的残余开始并且与基础识别的超残余得出结论的 TALE 重复的基于结构的重新分界。这个新数系统与到哪个故事合适的螺线管总科一致,并且反映 TAL 受动器的结构的正直。另外,它授与匹配界限 DNA 库的数字的故事重复的不可分的数字。我们然后与目标 DNA 分子在建筑群介绍设计 dHax3 变体的十五水晶结构,它阐明库腺嘌(A) 和 guanine (G) 由的识别的结构的基础报导或 uncharacterized 故事代码。最后,我们在一次故事重复以内分析了氨基酸残余的顺序结构关联。这里报导的结构的分析可以推进故事蛋白质的机械学的理解并且与改进亲密关系和特性便于 TALEN 的设计。 | Dong Deng Chuangye Yan Jianping Wu Xiaojing Pan Nieng Yan | 2014 | Protein & Cell2014，5，4： | 3 |
| 10 | Crystal structure of a bacterial homologue of SWEET transporters显示文摘 | Jing Wang Chuangye Yan Yini Li Kunio Hirata Masaki Yamamoto Nieng Yan Qi Hu | 2014 | Cell Research2014，24，12： | 3 |
| 11 | Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex by cryo-electron microscopy single particle analysis显示文摘The nuclear pore complex(NPC)exhibits structural plasticity and has only been characterized at local resolutions of up to 15 A for the cytoplasmic ring(CR).Here we present a single-particle cryo-electron microscopy(cryo-EM)structure of the CR from Xenopus laevis NPC at average resolutions of 5.5-7.9A,with local resolutions reaching 4.5 A.Improved resolutions allow identification and placement of secondary structural elements in the majority of the CR components.The two Y complexes in each CR subunit interact with each other and associate with those from flanking subunits,forming a circular scaffold.Within each CR subunit,the Nup358-containing region wraps around the stems of both Y complexes,likely stabilizing the scaffold.Nup205 connects the short arms of the two Y complexes and associates with the stem of a neighboring Y complex.The Nup214-containing region uses an extended coiled-coil to link Nup85 of the two Y complexes and protrudes into the axial pore of the NPC.These previously uncharacterized structural features reveal insights into NPC assembly. | Gaoxingyu Huang Yanqing Zhang Xuechen Zhu Chao Zeng Qifan Wang Qiang Zhou Qinghua Tao Minhao Liu Jianlin Lei Chuangye Yan Yigong Shi | 2020 | Cell Research2020，30，6： | 2 |
| 12 | Structure Design and Optimization of a New Type of Subsea Pipeline Connector显示文摘subsea 管道接头的一种新类型的基本配置基于出版社试穿原则被建议,并且一个参量的有限元素模型在 ANSYS 用 APDL 语言被创造。联合有限元素模型和优化技术,瞄准获得装载封上性能的力量和最佳的最小的尺寸优化被零个顺序优化方法设计。优化接头的实验被执行。结果显示结构的设计显著地改进了的最佳装载力量并且封上接头的性能的最小的指示物。 | Xiaoming Hu (1) Liquan Wang (2) Yong Liu (2) Rubo Ge (2) Lei Tan (2) Chuangye Fu (2) fu19880725@163.com Zongliang Wei (2) | 2012 | Journal of Marine Science and Application2012，11，1： | 2 |
| 13 | Cryo-EM structure of the inner ring from the Xenopus laevis nuclear pore complex显示文摘Nuclear pore complex(NPC)mediates nucleocytoplasmic shuttling.Here we present single-particle cryo-electron microscopy structure of the inner ring(IR)subunit from the Xenopus laevis NPC at an average resolution of 4.2Å.A homo-dimer of Nup205 resides at the center of the IR subunit,flanked by two molecules of Nup188.Four molecules of Nup93 each places an extended helix into the axial groove of Nup205 or Nup188,together constituting the central scaffold.The channel nucleoporin hetero-trimer of Nup62/58/54 is anchored on the central scaffold.Six Nup155 molecules interact with the central scaffold and together with the NDC1–ALADIN hetero-dimers anchor the IR subunit to the nuclear envelope and to outer rings.The scarce inter-subunit contacts may allow sufficient latitude in conformation and diameter of the IR.Our structure reveals the molecular basis for the IR subunit assembly of a vertebrate NPC. | Gaoxingyu Huang Xiechao Zhan Chao Zeng Ke Liang Xuechen Zhu Yanyu Zhao Pan Wang Qifan Wang Qiang Zhou Qinghua Tao Minhao Liu Jianlin Lei Chuangye Yan Yigong Shi | 2022 | Cell Research2022，32，5： | 1 |
| 14 | Prevalence of paroxysmal nocturnal hemoglobinuria in C hinese patients with B udd‐ C hiari syndrome or portal vein thrombosis显示文摘 | Xingshun Qi Chuangye He Guohong Han Zhanxin Yin Feifei Wu Qing Zhang Jing Niu Kaichun Wu Daiming Fan | 2012 | J Gastroenterol Hepatol2012，，1： | 1 |
| 15 | Transjugular Intrahepatic Portosystemic Shunt for Portal Cavernoma with Symptomatic Portal Hypertension in Non-cirrhotic Patients显示文摘 | Xingshun Qi Guohong Han Zhanxin Yin Chuangye He Jianhong Wang Wengang Guo Jing Niu Wei Zhang Ming Bai Daiming Fan | 2012 | Digestive Diseases and Sciences2012，，4： | 1 |
| 16 | Physical and mechanical properties of dental nanocompesites composed of aliphatic epoxy resin and epoxidized aromatic hyperbranched polymers 显示文摘 | Yujie Zhang Daohong Zhang Chuangye Qin | | Polymer Composites in press0，，： | 1 |
| 17 | Transarterial Chemoembolization for the Treatment of Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis: Prognostic Factors in a Single-Center Study of 188 Patients显示文摘 | Lei Liu Cheng Zhang Yan Zhao Xingshun Qi Hui Chen Wei Bai Chuangye He Wengang Guo Zhanxin Yin Daiming Fan Guohong Han Qing He | 2014 | BioMed Research International2014，，： | 1 |
| 18 | A complementarity for extended Langmuir method显示文摘 | Qingdao Wang Genxiang Luo Haoping Wang Chuangye Hou Jun Jin | 2006 | Journal of Colloid and Interface Science2006，，297： | 1 |
| 19 | Cryo-EM structure of the human mitochondrial translocase TIM22 complex显示文摘Dear Editor,Mitochondria are essential organelles in cellular metabolism,homeostasis,and apoptosis.1,2 Most mitochondrial proteins are synthesized as precursors in the cytosol and then imported into mitochondria by specific protein translocase complexes,including the translocase of the outer membrane complex(TOM complex),the carrier translocase of the inner membrane complex(TIM22 complex),the presequence translocase of the inner membrane complex(TIM23 complex),the sorting and assembly machinery(SAM complex),and the mitochondrial import complex(MIM complex).3 The TIM22 complex is responsible for the translocation and insertion of hydrophobic membrane proteins,including mitochondrial carrier proteins and translocase subunits(Tim17,Tim22 and Tim23).3 In humans,TIM22 is a 440-kDa complex comprising at least six components:the hypothetical channel-forming protein Tim22,three small Tim proteins(Tim9,Tim10a and Tim10b),Tim29 and acylglycerol kinase(AGK).1 Considering the functional importance of mitochondrial protein import,the TIM22 complex has been linked to many diseases.For example,mutations in the TIM22 gene have been reported to cause early-onset mitochondrial myopathy.4 AGK participates in lipid biosynthesis,and mutations in the AGK gene lead to Sengers syndrome.2 Mutations in the TIMM8A gene(also called DDP1)cause deafness dystonia syndrome. | Liangbo Qi Qiang Wang Zeyuan Guan Yan Wu Cuicui Shen Sixing Hong Jianbo Cao Xing Zhang Chuangye Yan Ping Yin | 2021 | Cell Research2021，31，3： | 1 |
| 20 | Dimeric structure of the uracil:proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters显示文摘Escherichia coli uracil:proton symporter UraA 是 nucleobase/ascorbate transporter (NAT ) 或 nucleobase/cation symporter 的一个原型的成员 2 (NCS2 ) 家庭,它对应于人的溶质搬运人家庭 SLC23。UraA 由被组织成二个不同领域,核心领域和门领域的 14 个 transmembrane 片断(TM ) 组成,也是的结构的褶层由 SLC4 和 SLC26 transporters 分享了。这里我们在场 UraA 的水晶结构在 2.5 点处于一个堵塞状态跳了到 uracil?分辨率。有以前报导的里面打开 UraA 的结构的比较象门领域的 intra 域重新整理一样揭示在核心领域和门领域之间的显著相对运动。堵塞 UraA 形式一在门领域被二个核心领域夹的结构更暗淡。在 vitro 并且在生物化学的描述显示出的 vivo,那 UraA 在平衡在之间更暗淡并且在所有测试净化的微粒的单体,当更暗淡的形成为运输活动是必要的时。在二聚的 UraA 和最近报导的里面面对的二聚的 UapA 之间的结构的比较提供重要卓见进 SLC23 transporters 的运输机制。 | Xinzhe Yu Guanghui Yang Chuangye Yan Javier L Baylon Jing Jiang He Fan Guifeng Lu Kazuya Hasegawa Hideo Okumura Tingliang Wang Emad Tajkhorshid Shuo Li Nieng Yan | 2017 | Cell Research2017，27，8： | 1 |
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