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| 1 | Influence of Water Stress on Endogenous Hormone Contents and Cell Damage of Maize Seedlings显示文摘Phytohormones play critical roles in regulating plant responses to stress. We investigated the effects of water stress induced by adding 12% (w/v) polyethylene glycol to the root medium on the levels of abscisic acid (ABA), indole-3-acid (IAA), zeatin (ZT), and gibberellin3 (GA3) in maize leaves. The results suggested that water stress had significant effects on the four hormone levels. There was a transient increase in the IAA content during the initial stage of adaptation to water stress in maize leaves, but it dropped sharply thereafter in response to water stress. ABA content increased dramatically in maize leaves after 24 h of exposure to water stress, and then the high levels of ABA were maintained to the end. The contents of ZT and GA3 rapidly declined in maize leaves subjected to water stress. The effects of water stress on chlorophyll content, electrolyte leakage and malondialdehyde levels in maize leaves were also studied. The variation of cell damage was negatively correlated with ZT and GA3 levels in maize leaves under water stress. Thus, we explored the roles of ZT and GA3 on the growth of maize seedlings under water stress by exogenous application. It is possible that both ZT and GA3 were effective in protecting maize seedlings from water stress, which would be of great importance for the improvement of drought tolerance in maize by genetic manipulation. | Chunrong Wang Aifang Yang Haiying Yin Juren Zhang | 2008 | Journal of Integrative Plant Biology2008，50，4： | 17 |
| 2 | Response of grain yield to plant density and nitrogen rate in spring maize hybrids released from 1970 to 2010 in Northeast China显示文摘The objective of this study was to identify the response of grain yield to plant density and nitrogen rate in spring maize hybrids released from 1970 to 2010 and grown extensively in Northeast China.Twenty-one hybrids were grown for 2 years in Northeast China at densities of 30,000,52,500,75,000,and 97,500 plants ha^(-1)and N application levels of 0,150,300,and 450 kg N ha^(-1).Irrespective of density or nitrogen application rate,grain yields both per plant and per unit area were significantly higher for newer than older hybrids.As plant density increased from 30,000 to 97,500 plant ha^(-1),yield per plant of 1970 s,1980 s,1990 s,and 2000 s hybrids decreased by 50%,45%,46%,and 52%,respectively.The response of grain yield per unit area to plant density was curvilinear.The estimated optimum plant densities were about 58,000,49,000,65,000,and 65,000 plants ha^(-1)for hybrids released in the 1970 s,1980s,1990 s,and 2000 s,respectively.The theoretical optimum densities for the hybrids released from the 1970 s to the 2000 s increased by 1750 plants ha^(-1)decade^(-1).Nitrogen fertilization significantly increased grain yields per plant and per unit area for all hybrids.The theoretical optimum N application rates for high yield for hybrids released in the 1970 s and 1980 s were about 280 and 360 kg ha^(-1),and the hybrids from the 1990 s and 2000 s showed highest yield at 330 kg ha^(-1)N.No significant difference in the grain yields of 2000 s hybrids between the N levels of 150 to 450 kg ha^(-1)was found.Significant yield gains per plant and per unit area were found,with average increases of 17.9 g plant^(-1)decade^(-1)and936 kg ha^(-1)decade^(-1)over the period 1970–2010,respectively.Yield gains were attributed mainly to increased yield per plant,contributed by increases in kernel number per ear and1000-kernel weight.The rates of lodging and barren plants of newer hybrids were significantly lower than those of older ones,especially at high plant density. | Chunrong Qian Yang Yu Xiujie Gong Yubo Jiang Yang Zhao Zhongliang Yang Yubo Hao Liang Li Zhenwei Song Weijian Zhang | 2016 | The Crop Journal2016，4，6： | 15 |
| 3 | Preparation and evaluation of biomimetric nano-hydroxyapatite-based composite scaffolds for bone-tissue engineering显示文摘In the present study,novel biomimetic composite scaffolds with a composition similar to that of natural bone were prepared,using nano-hydroxyapatite,collagen,and phosphatidylserine.The scaffolds possess an interconnected porous structure with a porosity of 84%.The pore size ranges from several micrometers up to about 400 m.In-vitro studies in simulated body fluids showed that the morphologies of the products derived from mineralization can be regulated by the extracellular matrix components of the scaffolds;this in turn leads to creation of a large number of hydroxyapatite crystals on the scaffold surface.The regulatory properties of collagen and phosphatidylserine also influenced the cell response to the composite scaffolds.MC3T3-E1 cells attached and spread on the surfaces of the materials and interacted with the substrates;this may be the result of charged groups on the composite materials.Radiological analysis suggested that calluses and bone bridges formed in defects within 12 weeks.These composite scaffolds may therefore be a suitable replacement in bone-tissue engineering. | YANG ChunRong WANG YingJun CHEN XiaoFeng | 2012 | Chinese Science Bulletin2012，57，21： | 9 |
| 4 | HIGH PERFORMANCE ELECTRIC FIELD MICRO SENSOR WITH COMBINED DIFFERENTIAL STRUCTURE显示文摘This paper presents a high performance electric field micro sensor with combined differential structure.The sensor consists of two backward laid micro-machined chips,each packaged by polymer and metal.The novel combined differential structure effectively reduces various environmental affections,such as thermal drift,humidity drift and electrostatic charge accumulation.The sensor is tested in near-ground place as well as balloon-borne sounding.In different weather conditions,the measurement results showed good agreement with those of the commercial electric field mill. | Wen Xiaolong Peng Chunrong Fang Dongming Yang Pengfei Chen Bo Zheng Fengjie Xia Shanhong | 2014 | Journal of Electronics(China)2014，31，2： | 7 |
| 5 | Progress in synthesis and application of zwitterionic Gemini surfactants显示文摘Zwitterionic Gemini surfactants have the Gemini molecular structure in which there are both multiple lipophilic groups and multiple hydrophilic groups.However,their hydrophilic groups have different charges.Due to the special molecular structure,this kind of surfactants possesses excellent properties,including high surface activities,isoelectric point(IP),low critical micelle concentration(CMC),less toxicity,low irritating,biodegradability,bioactive,interface modification,and so on.In this review,synthetic strategies of three kinds of zwitterionic Gemini surfactants,i.e.,an ioniccationic,cationic-nonionic and anionic-nonionic Gemini surfactants,are discussed,and their potential applications in life sciences,chemical industry and enhanced oil recovery(EOR)are illustrated.Their future development is also prospected. | Yuqiao CHENG Yang YANG Chunrong NIU Zhe FENG Wenhui ZHAO Shuang LU | 2019 | Frontiers of Materials Science2019，13，3： | 5 |
| 6 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 7 | Fabrication and oxidation resistance of silicon nitride fiber reinforced silica matrix wave-transparent composites显示文摘Wave-transparent ceramic matrix composites for the high temperature use should possess excellent oxidation resistance. In this work, Si3N4f/SiO2 composites with different fiber content were fabricated by filament winding and sol gel method. The oxidation resistance was investigated by tracking the response of flexural strength to the testing temperature. The results show that the flexural strength and toughness of the composites with fiber content of over 37% can reach high levels at around 175.0 MPa and 6.2 MPa m^1/2, respectively. After 1 h oxidation at 1100℃, the flexural strength drops a lot but can still reach 114.4 MPa, which is high enough to ensure the safety of structures. However, when the oxidation temperature rises to 1200–1400℃, the flexural strengths continue to fall to a relatively low level at 50.0–66.4 MPa. The degradation at high temperatures is caused by the combination of over strong interfacial bonding, the damage of fiber and the crystallization of silica matrix. | Xuejin Yang Bin Li Duan Li Changwei Shao Changrui Zhang Chunrong Zou Kun Liu | 2019 | Journal of Materials Science & Technology2019，35，12： | 4 |
| 8 | STUDY ON TYPHOON DISASTER LOSS AND RISK PREDICTION AND BENEFIT ASSESSMENT OF DISASTER PREVENTION AND MITIGATION显示文摘Based on the meteorological monitoring data of Typhoon Nesat and Haitang in Fujian Province in 2017, the data of the typhoon disaster situation and third-party evaluation of typhoon disaster prevention and mitigation benefit were investigated. By using the mean value anomaly estimation method in the similarity analysis method, it is estimated that typhoon Nesat and Haitang will cause direct economic losses of 0.8 ~ 1.8 billion yuan, and the typhoon disaster risk index evaluation model is used. The disaster risk pre-assessment of Typhoon Nesat and Haitang is carried out. The results of the study and analysis show that the pre-assessment results of Typhoon Nesat and Haitang are basically consistent with the actual disaster situation. The disaster loss was reduced to the minimum. According to the third party evaluation and investigation, it was concluded that the contribution rate of reducing economic benefits was 75% in Fujian Province for preventing and landing double typhoons Nesat and Haitang. Mainly reflected in the ship return to the port to avoid the wind, geological hazards prone to the site construction and cage culture danger removal reinforcement and other links; The contribution rate of reducing casualties is 86, mainly reflected in fishermen disembarkation and personnel transfer to safety emergency shelter and other links. The benefit of this double typhoon disaster prevention and mitigation in Fujian Province is about 0.6 billion yuan to reduce the direct economic loss. According to the investigation, the overall satisfaction of the double typhoon meteorological service is 91.0 points. Typhoon early warning information service convenience satisfaction is 91.4 points, early warning information accuracy satisfaction is 87.2 points, government departments strong anti-Taiwan disaster reduction organization, linkage departments participate in disaster prevention and mitigation high. However, there is a gap between public awareness and participation in typhoon disasters. | LIN YANG CHUNRONG CAO DEHUI WU HONGHUA QIU MINGHUI LU LING LIU | 2018 | Tropical Cyclone Research and Review2018，7，4： | 4 |
| 9 | Genomic characterizations of H4 subtype avian influenza viruses from live poultry markets in Sichuan province of China, 2014–2015显示文摘Dear Editor,Avian influenza viruses (AIVs) have posed a serious threat to poultry production and public health. To date, more than fourteen AIV subtypes that are able to infect human beings have been documented. Also, it is suggested that new subtypes may be reported in the future, owing to the migration of wild birds and live poultry transportation (Gao, 2018).Poultry may act as a potential incubator for novel subtypes of avian influenza virus (Bi et al., 2016a; Bi et al., 2016b; Liu et al., 2014a; Su et al., 2017). Up to date, the H7N9 AIV emerged in February 2013 has caused 1,567 human cases,with a fatality rate of 39.2%(http://www.who.int/influenza/ | Chuansong Quan Ting Huang Xiuwei Chen Jie Zhang Qianli Wang Cheng Zhang Tiyan Zhang Lijun Zhou Liumei Shu Chunrong Long Lei Yang Xunbo Du Yingze Zhao Peipei Liu Hao Song Weifeng Shi Yuhai Bi Qiang Lv William J.Liu George F.Gao | 2018 | Science China(Life Sciences)2018，61，9： | 4 |
| 10 | High-stability electrostatic field micro sensor for sounding thunderstorm applications显示文摘In this paper,the design and experimental results for a novel high-stability sounding electrostatic field micro sensor are presented.By means of hermetic chip sealing,digital weak signal demodulation unit,and probe sensor structure design,harsh environmental adaptation problems such as low temperature,high humidity,low air pressure,waterfall are solved.The sensor has a high resolution of 14 V/m,a wide measurement range of±100 kV/m,and is proved to have superior stability and performance in sounding electric field experiments than traditional sensors under different kinds of weather. | WEN Xiaolong PENG Chunrong FANG Dongming YANG Pengfei REN Tianling XIA Shanhong | 2014 | Instrumentation2014，1，3： | 3 |
| 11 | Combining immune checkpoint blockade with ATP-based immunogenic cell death amplifier for cancer chemo-immunotherapy显示文摘Amplifying“eat me signal”during tumor immunogenic cell death(ICD)cascade is crucial for tumor immunotherapy.Inspired by the indispensable role of adenosine triphosphate(ATP,a necessary“eat me signal”for ICD),a versatile ICD amplifier was developed for chemotherapy-sensitized immunotherapy.Doxorubicin(DOX),ATP and ferrous ions(Fe^(2+))were co-assembled into nanosized amplifier(ADO-Fe)throughπ‒πstacking and coordination effect.Meanwhile,phenylboric acid-polyethylene glycol-phenylboric acid(PBA-PEG-PBA)was modified on the surface of ADO-Fe(denoted as PADO-Fe)by the virtue of d-ribose unit of ATP.PADO-Fe could display active targetability against tumor cells via sialic acid/PBA interaction.In acidic microenvironment,PBA-PEG-PBA would dissociate from amplifier.Moreover,high H_(2)O_(2)concentration would induce hydroxyl radical(·OH)and oxygen(O_(2))generation through Fenton reaction by Fe^(2+).DOX and ATP would be released from the amplifier,which could induce ICD effect and“ICD adjuvant”to amplify this process.Together with programmed death ligands 1(PD-L1)checkpoint blockade immunotherapy,PADO-Fe could not only activate immune response against primary tumor,but also strong abscopal effect against distant tumor.Our simple and multifunctional ICD amplifier opens a new window for enhancing ICD effect and immune checkpoint blockade therapy. | Jiulong Zhang Xiaoyan Sun Xiufeng Zhao Chunrong Yang Menghao Shi Benzhuo Zhang Haiyang Hu Mingxi Qiao Dawei Chen Xiuli Zhao | 2022 | Acta Pharmaceutica Sinica B2022，12，9： | 2 |
| 12 | Cognitive factors associated with the willingness for HIV testing among pregnant women in China显示文摘 | Li Chunrong Yang Liu Kong Jinwang | 2014 | Chinese Medical Journal2014，，19： | 2 |
| 13 | Dynamic localization and the associated translocation mechanism of HMGBs in response to GCRV challenge in CIK cells显示文摘高活动性的组盒子(HMGB ) 蛋白质,联系染色质的原子蛋白质的一个家庭,惊人地在哺乳动物的免疫系统起 multifaceted 作用。因此远,很少在 teleosts 对 HMGB 的 nucleocytoplasmic 分发被知道。现在的学习系统地在 Ctenopharyngodon idella 调查了所有六 HMGB 蛋白质的动态本地化肾(CIK ) 房间。在基础条件下面,对原子核只局部性的所有 HMGB。草鲤鱼 reovirus (GCRV ) , polyinosinic-polycytidylic (poly (I∶ C )) 钾盐和 lipopolysaccharide (LPS ) 质问唤起了 HMGB 的原子出口到各种各样的度:GCRV 挑战导致了 CiHMGB2b 的最高原子的出口,并且 poly (I∶ C ) 并且 LPS 唤起了 CiHMGB1b 的最高的 nucleocytoplasmic shuttling。总的来说, CiHMGB2a 和 CiHMGB3b 的 nucleocytoplasmic shuttling 被这些挑战很少导致。动态成像揭开了 nucleocytoplasmic CiHMGB2b 的导致 GCRV 的重定位在经历 karyotheca 破裂, apoptosis 或增长的房间发生了。西方的污点分析被用来在整个房间 lysates, cytosol,原子部分和文化媒介检验 HMGB-EGFP 熔化蛋白质。进一步的调查表明了 N 终端 HMG 盒子的原子保留和 C 终端酸的尾巴的 nucleocytoplasmic 分发。动态重定位的比较分析全身,截断或妄想的 HMGB 证实在 HMG 盒子和 C 尾巴领域之间的 intramolecular 相互作用调停了 HMGB 的 nucleocytoplasmic translocation。这些结果不仅提供 HMGB 的 subcellular 本地化的全面理解,而且由 GCRV 挑战揭示 HMGB 的 nucleocytoplasmic translocation 的正式就职机制,它在 teleosts 的天生的免疫在病原体, HMGB 和模式识别受体之中在相互作用上为进一步的研究打一个基础。 | Youliang Rao Jianguo Su Chunrong Yang Nana Yan Xiaohui Chen Xiaoli Feng | 2015 | Cellular & Molecular Immunology2015，12，3： | 2 |
| 14 | Identifica- tion, characterization and immunological response analysis of stimulator of interferon gene (STING) from grass carp Cteno- pharyngodon idella显示文摘 | Feng Xiaoli Yang Chunrong Zhang Yixuan | 2014 | Develop Comps Immunol2014，45，1： | 1 |
| 15 | Mineralization regulation and biological influence of bioactive glass-collagen-phosphatidylserine composite scaffolds显示文摘Biomimetic scaffolds are appealing products for the repair of bone defects using tissue engineering strategies.In the present study,novel biomimetic composite scaffolds,with similar properties to natural bone,were prepared,blended and cross-linked with bioactive glass,type I collagen and phosphatidylserine.When exposed to cell culture solution in the absence of a cellular source,the composite scaffolds form crystals with octahedral structure.These crystals are similar to the products derived from MC3T3-E1 cell mineralization within the composite scaffolds,with respect to both composition and morphology.Furthermore,crystals with octahedral structure were observed to develop into plate-like hydroxyapatite.The bio-mineralization behavior of the composite scaffolds is likely influenced by inorganic components.Finally,a rabbit tibia defect model shows that the highly bioactive properties of the investigated composites result in excellent bone repair. | YANG ChunRong WANG YingJun CHEN XiaoFeng | 2012 | Science China(Life Sciences)2012，55，3： | 1 |
| 16 | Development and characterization of novel biomimetic composite scaffolds based on bioglass-collagen-hyaluronicacid-phosphatidylsefine for tissue engineering applications显示文摘 | Wang Yingjun Yang Chunrong Chen Xiaofeng | 2006 | Macromol Mater Eng2006，291，： | 1 |
| 17 | Synthesis and Anticoccidial Activities of Novel N-(2-Aminophenyl)-2-quinazolinone-acetamide Hydrochloride显示文摘 | Yan Chunrong Yang Li Guo Arong | 2013 | Asian Journal of Chemistry2013，25，9： | 1 |
| 18 | Design, fabrication and application of an SOI-based resonant electric field microsensor with coplanar comb-shaped electrodes显示文摘 | YANG Pengfei PENG Chunrong FANG Dongming | 2013 | Journal of Micromechanics and Microengineering2013，23，055： | 1 |
| 19 | Distributed implantation of a flexible microelectrode array for neural recording显示文摘Flexible multichannel electrode arrays(fMEAs)with multiple flaments can be flexibly implanted in various patterns.It is necessary to develop a method for implanting the fMEA in different locations and at various depths based on the recording demands.This study proposed a strategy for reducing the microelectrode volume with integrated packaging.An implantation system was developed specifically for semiautomatic distributed implantation.The feasibility and convenience of the fMEA and implantation platform were verified in rodents.The acute and chronic recording results provied the effectiveness of the packaging and implantation methods.These methods could provide a novel strategy for developing fMEAs with more flaments and recording sites to measure functional interactions across multiple brain regions. | Chunrong Wei Yang Wang Weihua Pei Xinyong Han Longnian Lin Zhiduo Liu Gege Ming Ruru Chen Pingping Wu Xiaowei Yang Li Zheng Yijun Wang | 2022 | Microsystems & Nanoengineering2022，8，3： | 1 |
| 20 | Development and characterization of novel biomimetic composite scaffolds based on bioglass-collagen-hyaluronic acidphosphatidylserine for tissue engineering applications显示文摘 | Wang Yingjun Yang Chunrong Chen Xiaofeng | 2006 | Macromol Mater Eng2006，291，3： | 1 |
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