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| 1 | Cyclosporine versus tacrolimus in patients with HCV infection after liver transplantation:Effects on virus replication and recurrent hepatitis显示文摘瞄准:决定 calcineurin 禁止者, cyclosporine 和 tacrolimus 的效果,在丙肝上,在病人的周期性的丙肝的病毒(HCV ) 复制和活动张贴肝移植。方法:在我们的中心为在 1999 和 2003 之间的联系 HCV 的肝肝硬化收到了肝移植的 107 个病人的一个队的数据回顾地被分析。浆液 HCV-RNA 的水平和周期性的肝炎的活动在作为主要抑制免疫力的代理人和没在移植以后在开始的 12 瞬间以内导致胆汁的复杂并发症的不那样类似的抑制免疫力的政体收到了 cyclosporine 或 tacrolimus 的 47 个病人之间被比较。结果:HCV-RNA 在移植以后在 3 瞬间以内增加了,但是 cyclosporine 组和 tacrolimus 组之间的差别是不足道的(在 12 瞬间的 P=0.49 ) 。另外,由浆液 transaminases 决定了的周期性的肝炎并且门发炎和纤维变性的组织学的分级没在 12 瞬间(P=0.34 ) 以后显示出有效差量。结论:一个主要抑制免疫力的代理人不在肝移植以后在感染 HCV 的病人影响周期性的肝炎的正式就职或严厉的 Cyclosporine 或 tacrolimus。 | Philip Hilgard Alisan Kahraman Nils Lehmann Cornelia Seltmann Susanne Beckebaum R Stefan Ross Hideo A Baba Massimo Malago Christoph E Broelsch Guido Gerken | 2006 | World Journal of Gastroenterology2006，12，5： | 235 |
| 2 | Prognostic significance of tumor immune microenvironment and immunotherapy:Novel insights and future perspectives in gastric cancer显示文摘Despite a decrease in gastric cancer incidence, the development of novel biologic agents and combined therapeutic strategies, the prognosis of gastric cancer remains poor. Recently, the introduction of modern immunotherapy, especially using immune checkpoint inhibitors, led to an improved prognosis in many cancers. The use of immunotherapy was also associated with manageable adverse event profiles and promising results in the treatment of patients with gastric cancer, especially in heavily pretreated patients. These data have led to an accelerated approval of some checkpoint inhibitors in this setting. Understanding the complex relationship between the host immune microenvironment and tumor and the immune escape phenomenon leading to cancer occurrence and progression will subsequently lead to the identification of prognostic immune markers. Furthermore, this understanding will result in the discovery of both new mechanisms for blocking tumor immunosuppressive signals and pathways to stimulate the local immune response by targeting and modulating different subsets of immune cells. Due to the molecular heterogeneity of gastric cancers associated with differentclinico-biologic parameters, immune markers expression and prognosis, novel immunotherapy algorithms should be personalized and addressed to selected subsets of gastric tumors, which have been proven to elicit the best clinical responses. Future perspectives in the treatment of gastric cancer include tailored dual immunotherapies or a combination of immunotherapy with other targeted agents with synergistic antitumor effects. | Daniela Cornelia Lazǎr Mihaela Flavia Avram Ioan Romosan Mǎrioara Cornianu Sorina Tǎan Adrian Goldis | 2018 | World Journal of Gastroenterology2018，24，32： | 24 |
| 3 | Black locust(Robinia pseudoacacia L.)as a multi-purpose tree species in Hungary and Romania:a review显示文摘Black locust(Robinia pseudoacacia L.) was the first North-American tree species imported to Europe at the beginning of the seventeenth century. It is commonly planted worldwide because of its adaptability to environmental stresses, its valuable wood, easy propagation, frequent and abundant seed production, excellent coppicing,high seedling survival, and relatively high wood yield. In Europe, Romania and Hungary have the most highly-developed black locust growing techniques and experiences.As a result of increasing interest in black locust in many countries, this review aims to provide a comprehensive overview of state-of-the-art site requirements, propagation, improvement and management(including growth and yield as well as use in energy plantations). | Valeriu-Norocel Nicolescu Cornelia Hernea Beatrix Bakti Zsolt Keseru Borbála Antal Károly Rédei | 2018 | Journal of Forestry Research2018，29，6： | 2 |
| 4 | Infectious, atopic and inflammatory diseases, childhood adversities and familial aggregation are independently associated with the risk for mental disorders: Results from a large Swiss epidemiological study显示文摘AIM To examine the associations between mental disorders and infectious, atopic, inflammatory diseases while adjusting for other risk factors.METHODS We used data from PsyC oL aus, a large Swiss Population Cohort Study(n = 3720; age range 35-66). Lifetime diagnoses of mental disorders were grouped into the following categories: Neurodevelopmental, anxiety(early and late onset), mood and substance disorders. They were regressed on infectious, atopic and other inflammatory diseases adjusting for sex, educational level, familial aggregation, childhood adversities and traumatic experiences in childhood. A multivariate logistic regression was applied to each group of disorders. In a complementary analysis interactions with sex were introduced via nested effects. RESULTS Associations with infectious, atopic and other chronic inflammatory diseases were observable together with consistent effects of childhood adversities and familial aggregation, and less consistent effects of trauma in each group of mental disorders. Streptococcal infections were associated with neurodevelopmental disorders(men), and measles/mumps/rubella-infections with early and late anxiety disorders(women). Gastric inflammatory diseases took effect in mood disorders(both sexes) and in early disorders(men). Similarly, irritable bowel syndrome was prominent in a sex-specific way in mood disorders in women, and, moreover, was associated with early and late anxiety disorders. Atopic diseases were associated with late anxiety disorders. Acne(associations with mood disorders in men) and psoriasis(associations with early anxiety disorders in men and mood disorders in women) contributed sex-specific results. Urinary tract infections were associated with mood disorders and, in addition, in a sex-specific way with late anxiety disorders(men), and neurodevelopmental and early anxiety disorders(women).CONCLUSION Infectious, atopic and inflammatory diseases areimportant risk factors for all groups of mental disorders. The sexual dimorphism of the associations is pronounced. | Vladeta Ajdacic-Gross Aleksandra Aleksandrowicz Stephanie Rodgers Margot Mutsch Anja Tesic Mario Müller Wolfram Kawohl Wulf R?ssler Erich Seifritz Enrique Castelao Marie-Pierre F Strippoli Caroline Vandeleur Roland von K?nel Rosa Paolicelli Markus A Landolt Cornelia Witthauer Roselind Lieb Martin Preisig | 2016 | World Journal of Psychiatry2016，6，4： | 2 |
| 5 | Management of Diabetes Mellitus Complicating Pregnancy 显示文摘 | Steven G Gabbe MD Cornelia R | 2003 | Am Obstetrics and Gynecologists2003，10，： | 1 |
| 6 | Management of diabetes mellitus complicating pregnancy 显示文摘 | Steven G Gabble M D Cornelia R | 2003 | Obstet Gynecol2003，102，4： | 1 |
| 7 | Sensory memory during physiological aging indexed by mismatch negativity (MMN)显示文摘 | Manuela R Cornelia P Debora B | 2012 | Neurobiology of Aging2012，625，： | 1 |
| 8 | Nonconvulsive status epilepticus 显示文摘 | Maganti R Paula Gerber Cornelia Drees | 2008 | Epilepsy Behav2008，12，4： | 1 |
| 9 | Huber quantitative urine particle analysis:integrative approach for the optimal combination of automation with UF-100 and microscopic review with KOVA cell chamber显示文摘 | CORNELIA O ANDREAS R | 2003 | Clin Chem2003，49，： | 1 |
| 10 | Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs显示文摘 | van de Steeg Evita Wagenaar Els van der Kruijssen Cornelia M M Burggraaff Johanna E C de Waart Dirk R Elferink Ronald P J Oude Kenworthy Kathryn E Schinkel Alfred H | 2010 | Journal of Clinical Investigation2010，，8： | 1 |
| 11 | An analysis of operations efficiency in large-scale distribution systems显示文摘 | Cornelia D | 2004 | Journal of Operations Management2004，21，3： | 1 |
| 12 | Management of diabetes mellitus complicating pregnancy显示文摘 | Steven G Gabble MD Cornelia R | 2003 | Obstet Gynecol2003，102，4： | 1 |
| 13 | An integrated benchmarking approach to distribution center performance using DEA modeling显示文摘 | ANTHONY R CORNELIA D | 2002 | Journal of Operations Management2002，20，1： | 1 |
| 14 | Metal-catalyzed aetiva- tion of ethers via C-O bond cleavage: A new strategy for molecular diversity 显示文摘 | Cornelia J Zarate C Martin R | 2014 | Chem Soc Rev2014，43，23： | 1 |
| 15 | Extended Resections for Hilar Cholangiocarcinoma显示文摘 | Peter Neuhaus Sven Jonas Wolf O. Bechstein Rüdiger Lohmann Cornelia Radke Norbert Kling Cora Wex Hartmut Lobeck Rainer Hintze | 1999 | Annals of Surgery1999，，6： | 1 |
| 16 | Topological analysis of a putative virB8 homologue essential for the cag type IV secretion system in Helicobacter pylori显示文摘 | Buhrdorf R Cornelia F Haas R | 2003 | Int J Med Microbiol2003，293，： | 1 |
| 17 | Formation of the sinus node head and differentiation of sinus node myocardium are independently regulated by Tbx18 and Tbx3显示文摘 | Cornelia W Thomas G Airik R | 2009 | Circ Res2009，104，3： | 1 |
| 18 | Manage- ment of diabetes mellitus complicating pregnancy显示文摘 | STEVEN G GABBLE M D CORNELIA R | 2003 | Obstet Gynecol2003，12，4： | 1 |
| 19 | Crystallization of rodshaped fluoroapatite from glass melts in the system SiO2-Al2O3-CaO-P2O5-Na2O-K2O-F显示文摘 | Cornelia M Carsten J Christian R | 1999 | J Non-Crystalline Solids1999，248，： | 1 |
| 20 | An integrated benchmarking approach to distribution center performance using DEAmodeling显示文摘 | ANTHONY R CORNELIA D | 2002 | Journal of Operations Management2002，20，1： | 1 |
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