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| 1 | 重复经颅磁刺激治疗抑郁症的机制研究进展(英文)显示文摘概述:抑郁障碍是目前最常见的心理健康问题之一。然而,对于该疾病的基于机制的治疗方法仍然是难以捉摸的。重复经颅磁刺激(rTMS)是一种非侵入性的程序,它可以以一种脉冲磁场来刺激大脑中的电活动,被认为是一种有效的抑郁症治疗方式。在这里,我们回顾了关于rTMS治疗抑郁症的临床和基础研究的主要发现,包括它的抗抑郁疗效,基本原理,调节神经回路、神经递质和脑网络、海马神经发生、和突出的功效,以及分子通路。 | Zhengwu PENG Cuihong ZHOU Shanshan XUE Jie BAI Shoufen YU Xiaosa LI Huaning WANG Qingrong TAN | 2018 | 上海精神医学2018，30，2： | 13 |
| 2 | The heme oxygenase-1 inhibitor ZnPPIX induces non-canonical, Beclin 1-independent, autophagy through p38 MAPK pathway显示文摘 | Cuihong Zhou Jun Zhou Fugeng Sheng Haichuan Zhu Xiaoyan Deng Bin Xia Jian Lin | 2012 | Acta Biochimica et Biophysica Sinica2012，44，10： | 5 |
| 3 | Experimental continuous sludge microwave system to enhance dehydration ability and hydrogen production from anaerobic digestion of sludge显示文摘Dehydrating large amounts of sludge produced by sewage treatment plants is difficult.Microwave pretreatment can effectively and significantly improve the dewaterability and hydrogen production of sludge subjected to anaerobic digestion. The aim of this study was to investigate the effects of different microwave conditions on hydrogen production from anaerobic digestion and dewaterability of sludge. Based on an analysis of the electric field distribution, a spiral reactor was designed and a continuous microwave system was built to conduct intermittent and continuous experiments under different conditions. Settling Volume, Capillary Suction Time, particle size, and moisture content of the sludge were measured. The results show that sludge pretreatment in continuous experiments has equally remarkable dehydration performance as in intermittent experiments; the minimum moisture content was 77.29% in the intermittent experiment under a microwave power of 300 W and an exposure time of 60 sec, and that in the continuous experiment was 77.56% under a microwave power of 400 W and an exposure time of 60 sec.The peak measured by Differential Scanning Calorimeter appeared earliest under a microwave power of 600 W and an exposure time of 180 sec. The heat flux at the peak was 4.343 W/g, which is relatively small. This indicates that microwave pretreatment induced desirable effects. The maximum yield of hydrogen production was 7.967% under the conditions of microwave power of 500 W, exposure time of 120 sec, and water bath at 55°C. This research provides a theoretical and experimental basis for the development of a continuous microwave sludge-conditioning system. | Cuihong Zhou Xintong Huang Meng Zeng | 2018 | Journal of Environmental Sciences2018，30，5： | 4 |
| 4 | An improved bimolecular fluorescence complementation tool based on superfolder green fluorescent protein显示文摘双分子的荧光互补(BiFC ) 广泛地在最近的年里在 proteinprotein 相互作用(PPI ) 的分析被使用了。有象便利和在房间的 PPI 的直接可视化那样的 BiFC 的许多著名优点。然而, BiFC 有一普通限制:分开的非荧光灯的碎片能是自发地自我装配的进未经触动的蛋白质,它导致假积极的结果。在这研究,一双互补碎片(sfGFPN 和 sfGFPC ) 被切开在 214 和 215 氨基酸残余之间的 superfolder GFP (sfGFP ) 构造,并且 sfGFPC 被指导地点的基因 mutagenesis 变异减少否定控制的信号。我们的结果证明在 sfGFPC (sfGFPC (m12 )) 的变化能有效地减少否定控制的信号。因此,我们为 PPI 的分析提供一个改进 BiFC 工具。,推进自己组装问题是为 BiFC 的申请的一个普通缺点,我们的研究为另外的 BiFC 候选人蛋白质向可行策略提供一样的问题。 | Jun Zhou Jian Lin Cuihong Zhou Xiaoyan Deng Bin Xia | 2011 | Acta Biochimica et Biophysica Sinica2011，43，3： | 3 |
| 5 | Extension of continuous scanning laser Doppler vibrometry measurement for complex structures with curved surfaces显示文摘The continuous Scanning Laser Doppler Vibrometry(SLDV)developed on the base of the galvanometer scanner system has made it possible to quickly obtain the full field vibration responses within a rectangular area of the structure.In this paper,an arbitrary continuous scanning path generating method for Continuous Scanning Laser Doppler Vibometry(CSLDV)is further put forward in order to allow the CSLDV suitable for testing structures featured by complex shapes not just for regular areas.In the first step,the relationship between position of laser spot and the driving voltages of galvanometer scanner system has been described by a mathematical modeling.Then,a novel arbitrary scanning path generating strategy based on CSLDV is presented by deforming a normalization rectangular scanning path to an arbitrary continuous scanning path.The mapping relation between the normalization rectangular scanning path and arbitrary continuous scanning path is established using the reference points.In the second step,a compressor blade with curved surface was taken as an example for modal test using the proposed method.At the same time,a validated experiment was performed in SLDV.The results show the mode shapes derived from the extended CSLDV are in agreement with those from SLDV and the Modal Assurance Criterion(MAC)between the two are all greater than 0.96.They also demonstrate the feasibility and effectiveness of the proposed method for CSLDV test and show strong potential on further practical engineering applications. | Cuihong LIU Chaoping ZANG Biao ZHOU | 2020 | Chinese Journal of Aeronautics2020，33，12： | 3 |
| 6 | Ecotoxicological effects of polycyclic musks and cadmium on seed germination and seedling growth of wheat(Triticum aestivum)显示文摘Single and joint toxic effects of polycyclic musks including 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2benzopyran (HHCB) and 7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronapthalene (AHTN) and cadmium (Cd) on seed germination and seedling growth of wheat (Triticum aestivum) were investigated.The results showed that the toxicity sequence of HHCB toxic to wheat seed germination and seedling growth was similar to that of AHTN,that is,germination rate > shoot elongation > root elongation,while the toxicity of Cd was in the sequence of root elongation > shoot elongation > germination rate,according to the LC50 and EC50 values.It is suggested that polycyclic musks and Cd had different toxicological mechanisms.Root and shoot elongation of wheat might be good bioindicators for the contamination of polycyclic musks and Cd in soil.The mixture of polycyclic musks and Cd had synergistic effects on T.aestivum according to the equi-toxic mixture approach when root elongation was selected as the toxicological endpoint.Thus,the joint toxicity of HHCB and Cd was significantly higher than the single toxicity of HHCB or Cd,which was also confirmed by the EC50 mix value of the mixture (EC50 mix=0.530 TU mix).The EC50 mix value of the mixture of AHTN and Cd was 0.614 TU mix,which indicated that the mixture toxicity was strengthened when AHTN coexisted with Cd. | Cuihong Chen Qixing Zhou Yanyu Bao Yaning Li Ping Wang | 2010 | Journal of Environmental Sciences2010，22，12： | 2 |
| 7 | Enhancement of laccase production by Pleurotus ostreatus and its use for the decolorization of anthraquinone dye显示文摘 | Hou Hongman Zhou Jiti Wang Jing Du Cuihong | 2004 | Process Biochemistry2004，39，11： | 1 |
| 8 | A two-stage amplified PZT sensor for monitoring lung and heart sounds in discharged pneumonia patients显示文摘Assessment of lung and heart states is of critical importance for patients with pneumonia.In this study,we present a small-sized and ultrasensitive accelerometer for continuous monitoring of lung and heart sounds to evaluate the lung and heart states of patients.Based on two-stage amplification,which consists of an asymmetric gapped cantilever and a charge amplifier,our accelerometer exhibited an extremely high ratio of sensitivity to noise compared with conventional structures.Our sensor achieves a high sensitivity of 9.2V/g at frequencies less than 1000 Hz,making it suitable to use to monitor weak physiological signals,including heart and lung sounds.For the first time,lung injury,heart injury,and both lung and heart injuries in discharged pneumonia patients were revealed by our sensor device.Our sound sensor also successfully tracked the recovery course of the discharged pneumonia patients.Over time,the lung and heart states of the patients gradually improved after discharge.Our observations were in good agreement with clinical reports.Compared with conventional medical instruments,our sensor device provides rapid and highly sensitive detection of lung and heart sounds,which greatly helps in the evaluation of lung and heart states of pneumonia patients.This sensor provides a cost-effective alternative approach to the diagnosis and prognosis of pneumonia and has the potential for clinical and home-use health monitoring. | Hongbin Chen Shuai Yu Haiyang Liu Jie Liu Yongguang Mlao Dandan Wu Xiaoyu Pan Cuihong Zhou Yifeng Lei Sheng Liu | 2021 | Microsystems & Nanoengineering2021，7，4： | 0 |
| 9 | Differential expression analysis of matrix metallo-proteinase 20(MMP20) in human esophageal cancer显示文摘The aim of this study was to investigate the different expressions of MMP20 in the process of esophageal cancer. RT-PCR, immunohistochemistry and Western blot were employed to detect the mRNA expression and protein expression of MMP20. Compared with the corresponding normal esophagus tissues, results showed the common trend of the dramatical overexpression of MMP20 in the esophageal cancer tissues. The analysis of MMP20 expression in different clinical early stages of esophageal cancer by RT-PCR indicated that MMP20 was much more overexpressed in the esophageal cancer with invasion than in the early stages. This suggested that MMP20 might play an important role in the progression of esophageal cancer. It probably plays a critical role in tumor invasion. | YANG Cuihong LIU Zhihua WANG Qun LUO Aiping SUN Yuntian ZHANG Xun WANG Xiuqin ZHOU Chuannong WU Min | 2001 | Chinese Science Bulletin2001，46，12： | 0 |
| 10 | Dithienylethene metallodendrimers with high photochromic efficiency显示文摘It has been challenging to achieve multi-photochromic systems without affecting the individual photoswitching properties of the constituent units. Herein, we present the design and synthesis of a new family of platinum-acetylide dendrimers containing up to twenty-one photochromic dithienylethene(DTE)units that exhibit both high photochromic efficiency and individual switching properties. Upon irradiation with ultraviolet(UV) and visible(vis) light, the resultant metallodendrimers display high conversion yield and good fatigue resistance. More interestingly, cyclization-cycloreversion kinetics revealed that the photochromic property of each DTE unit in these metallodendrimers is unaffected by its neighbor and the full ring-closure of up to twenty-one DTE units in one single dendrimer has been achieved. | Yuxuan Wang Qifeng Zhou Xiaoxiao He Ying Zhang Hongwei Tan Jianhua Xu Cuihong Wang Wei Wang Xiping Luo Jinquan Chen Lin Xu | 2022 | Chinese Chemical Letters2022，33，3： | 0 |
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