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| 1 | Initial study of biexponential model of intravoxel incoherent motion magnetic resonance imaging in evaluation of the liver fibrosis显示文摘 | Chen Cuiyun Wang Bin Shi Dapeng Fu Fangfang Zhang Jiliang Wen Zejun Zhu Shaocheng Xu Junling Lin Qing Li Jing Dou Shewei | 2014 | Chinese Medical Journal2014，，17： | 15 |
| 2 | Antisense MMP-9 RNA inhibits malignant glioma cell growth in vitro and in vivo显示文摘The matrix-degrading metalloproteinases (MMPs), particularly MMP-9, play important roles in the pathogenesis and development of malignant gliomas. In the present study, the oncogenic role of MMP-9 in malignant glioma cells was investigated via antisense RNA blockade in vitro and in vivo. TJ905 malignant glioma cells were transfected with pcDNA3.0 vector expressing antisense MMP-9 RNA (pcDNA-AS-MMP9), which significantly decreased MMP-9 expression, and cell proliferation was assessed. For in vivo studies, U251 cells, a human malignant glioma cell line, were implanted subcutaneously into 4-to 6-week-old BALB/c nude mice. The mice bearing well-established U251 gliomas were treated with intratumoral pcDNA-AS-MMP9-Lipofectamine complex (AS-MMP-9-treated group), subcutaneous injection of endostatin (endostatin-treated group), or both (combined therapy group). Mice treated with pcDNA (empty vector)-Lipofectamine served as the control group. Four or eight weeks later, the volume and weight of tumor, MMP-9 expression, microvessel density and proliferative activity were assayed. We demonstrate that pcDNA-AS-MMP9 significantly decreased MMP-9 expression and inhibited glioma cell proliferation. Volume and weight of tumor, MMP-9 expression, microvessel density and proliferative activity in the antisense-MMP-9-treated and therapeutic alliance groups were significantly lower than those in the control group. The results suggest that MMP-9 not only promotes malignant glioma cell invasiveness, but also affects tumor cell proliferation. Blocking the expression of MMP-9 with antisense RNA substantially suppresses the malignant phenotype of glioma cells, and thus can be used as an effective therapeutic strategy for malignant gliomas. | Cuiyun Sun Qian Wang Hongxu Zhou Shizhu Yu Alain R. Simard Chunsheng Kang Yanyan Li Yanling Kong Tongling An Yanjun Wen Fudong Shi Junwei Hao | 2013 | Neuroscience Bulletin2013，29，1： | 14 |
| 3 | Optimization of parameters on photocatalytic degradation of chloramphenicol using TiO_2 as photocatalyist by response surface methodology显示文摘The experimental design methodology was applied for modeling and optimizing the operation parameters on photocatalytic degradation of chloramphenicol (CAP) using TiO 2 as photocatalyst in a photoreactor. Three experimental parameters (including pH, TiO 2 concentration and CAP initial concentration) were adopted to obtain the preliminary information. The multivariate experimental design was employed to establish a quadratic model as a functional relationship between the degradation rate of CAP and three experimental parameters. The interaction effects and optimal parameters were obtained by using Design Expert software. The optimal values of the operation parameters under the related constraint conditions were found at pH 6.4, TiO 2 concentration of 0.94 g/L and CAP initial concentration of 19.97 mg/L, respectively. The degradation rate of CAP approached 85.97% under optimal conditions. The regression analysis with R 2 value of 0.9519 had a good agreement between the experimental results and the predictive values. In addition, pH and TiO 2 concentration had a significant influence on the degradation rate of CAP. | Junwei Zhang Dafang Fu Yunda Xu Cuiyun Liu | 2010 | Journal of Environmental Sciences2010，22，8： | 13 |
| 4 | Effects of ambient air pollution on allergic rhinitis among preschool children in Changsha, China显示文摘Prevalence of allergic rhinitis has rapidly increased among Chinese children,but the reasons are unclear.Recent findings have suggested that exposure to outdoor air pollutants may increase the risk of allergic rhinitis,but the results were inconsistent.This study further investigated the effect of outdoor air pollutants on allergic rhinitis among preschool children.A standardized questionnaire on health,home and environmental factors was conducted for 4988 children aged 1–8 in the city of Changsha,and the concentrations of PM10(particle diameter 10 m),sulfur dioxide(SO2)and nitrogen dioxide(NO2)during 2006–2011 were acquired from the official web of Changsha Environmental Protection Agency.Results showed that the prevalence of children’s doctor diagnosed rhinitis was 8.4%(95%confidence interval[CI]7.0%–10.0%).It was found that the prevalence of rhinitis was not associated with site-specific background concentrations of air pollutants,but significantly positively correlated with age-related accumulative personal exposure of PM10,SO2and NO2.We conclude that age-related accumulative personal exposure to ambient air pollution may play an important role in the development of rhinitis. | LU Chan DENG QiHong OU CuiYun LIU WeiWei SUNDELL Jan | 2013 | Chinese Science Bulletin2013，58，34： | 7 |
| 5 | Genome evolution trend of common carp (Cyprinus carpio L.) as revealed by the analysis of microsatellite loci in a gynogentic family显示文摘Genome evolution arises from two main ways of duplication and reduction. Fish specific genome duplication (FSGD) may have occurred before the radiation of the teleosts. Common carp (Cyprinus carpio L.) has been considered to be a tetraploid species, because of its chromosome numbers (2n=100) and its high DNA content. Using 69 microsatellite primer pairs, the variations were studied to better understand the genome evolution (genome duplication and diploidization) of common carp from a gynogenetic family. About 48% of primer pairs were estimated to amplify duplicates based on the number of PCR amplification per individual. Segregation patterns in the family suggested a partially duplicated genome structure and disomic inheritance. This indicates that the common carp is tetraploid and polyploidy occurred by allotetraploidy. Two primer pairs (HLJ021 and HLJ332) were estimated to amplify reduction based on the number of PCR amplification per individual. One allele in HLJ002 locus and HLJ332 locus was clearly lost in the gynogenetic family and the same as in six wild populations. Segregation patterns in the family suggested a partially diplodization genome structure. A hypothesis transition (dynamic) and equilibrium (static) were proposed to explain the common carp genome evolution between genome duplication and diploidization. | Yah Zhang Liqun Liang Peng Jiang Dayu Li Cuiyun Lu Xiaowen Sun | 2008 | Journal of Genetics and Genomics2008，35，2： | 7 |
| 6 | A consensus linkage map of common carp (Cyprinus carpio L.) to compare the distribution and variation of QTLs associated with growth traits显示文摘The ability to detect and identify quantitative trait loci (QTLs) in a single population is often limited. Analyzing multiple populations in QTL analysis improves the power of detecting QTLs and provides a better understanding of their functional allelic variation and distribution. In this study, a consensus map of the common carp was constructed, based on four populations, to compare the distribution and variation of QTLs. The consensus map spans 2371.6 cM across the 42 linkage groups and comprises 257 microsatellites and 421 SNPs, with a mean marker interval of 3.7 cM/marker. Sixty-seven QTLs affecting four growth traits from the four populations were mapped to the consensus map. Only one QTL was common to three populations, and nine QTLs were detected in two populations. However, no QTL was common to all four populations. The results of the QTL comparison suggest that the QTLs are responsible for the phenotypic variability observed for these traits in a broad array of common carp germplasms. The study also reveals the different genetic performances between major and minor genes in different populations. | ZHENG XianHu KUANG YouYi LV WeiHua CAO DingChen ZHANG XiaoFeng LI Chao LU CuiYun SUN XiaoWen | 2013 | Science China(Life Sciences)2013，56，4： | 4 |
| 7 | Shrinkage of Mt. Bogda Glaciers of Eastern Tian Shan in Central Asia during 1962–2006显示文摘Many small mountain glaciers have been reported undergoing strong shrinkage, and it is therefore important to understand how they respond to climate change. The availability of topographic maps from 1962, Landsat TM imagery from 1990 and ASTER(Advanced Spaceborne Thermal Emission and Radiometer) imagery from 2006 and field investigation of some glaciers allow a comprehensive analysis of glacier change based on glacier size and topography on Mt. Bogda. Results include:(1) an overall loss of a glacierized area by 31.18±0.31 km^2 or 21.6% from 1962 to 2006,(2) a marked dependence of glacier area shrinkage on initial size, with smaller glaciers experiencing higher shrinkage levels,(3) the disappearance of 12 small glaciers,(4) a striking difference in area loss between the southern and northern slopes of 25% and 17%, respectively. A subset of the investigated glaciers shows that the area 57.45±0.73 km2 in 1962 reduced to 54.79±0.561 km^2 in 1990 and 48.88±0.49 km^2 in 2006, with a relative area reduction of 4.6% during 1962–1990, and 10.8% during 1990–2006. The corresponding volume waste increased from 6.9% to 10.2%. Three reference glaciers were investigated in 1981 and revisited in 2009. Their terminus experienced a marked recession. Meteorological data from stations around Mt. Bogda reveals that glacier shrinkage is correlated with winter warming and an extension of the ablation period. Precipitation on the northwest side of the range shows a marked increase, with a slight increase on the southeast side. | Kaiming Li Zhongqin Li Cuiyun Wang Baojuan Huai | 2016 | Journal of Earth Science2016，27，1： | 3 |
| 8 | Genesis of Geothermal Fluid in Typical Geothermal Fields in Western Sichuan,China显示文摘The hydrogeochemical characteristics of geothermal fluids can reveal the genesis of geothermal systems and act as important references for developing and using geothermal resources.This study presents hydrogeochemical processes and thermal cycle mechanisms of typical geothermal fields in Western Sichuan.Based on the geological conditions in Western Sichuan,29 hot springs in three geothermal fields in the Batang and Litang areas were selected for hydrochemical and isotopic(δD andδ18O)analyses.Furthermore,the temperature of the thermal reservoir was calculated and the upflow cooling process of the hot springs was analyzed.Most of the subterranean hot waters in Batang and Litang are of the HCO3-Na hydrochemical type.The ion variation in Batang is primarily affected by water-rock interactions.There is a strong positive correlation between Na+,B?,and Cl?in Litang,suggesting that they have the same material source.The Na+and metaboric acid content is relatively high,which indicates that the groundwater runoff in both areas is relatively long-lasting,with reduced flow velocity;moreover,the metasilicic acid content is relatively high,which supports this conclusion.Both hydrogen and oxygen isotopes plot near the atmospheric precipitation line,indicating that groundwater recharge is functionally obtained from precipitation.The calculated thermal storage temperatures in Batang and Litang were 88–199℃ and 96–154℃,respectively.The proportion of cold water mixing in Batang was 64%–67%,while that in Litang was 60%–68%.According to the calculated results,the initial thermal cycle depth of the Batang area(4540–4780 m)was greater than that of the Litang area(3150–3960 m).The enthalpy of the deep parental geothermal fluid in Batang was 1550 J/g with a Cl^(-)concentration of 37 mg/L,while that in Litang was 2100 J/g with a Cl^(-)concentration of 48 mg/L. | ZHAO Jiayi WANG Guiling ZHANG Cuiyun XING Linxiao LI Man ZHANG Wei | 2021 | Acta Geologica Sinica(English Edition)2021，95，3： | 2 |
| 9 | Effect of Starch Sources on the Release Rates of Herbicides Encapsulated显示文摘The effects of starch sources on the behaviors of starch matrices and on the rates of herbicides released from the matrices were studied for slow release. The starches considered include native corn starch, wheat starch, potato starch and cassava starch. The matrices were prepared through encapsulating 2,4-dichlorophenoxyacetic or 2,4,5-trichlorophenoxyacetic acids as model herbicides with hot-gelatinized starch pastes. The encapsulation was evaluated in terms of herbicide content, swellability, encapsulation efficiency, and release rate. The results show that starch sources play an important role on the matrix behaviors and on release rates. The rate of 2,4-D released follows the order: wheat starch < potato starch < corn starch < cassava starch. And for the rate of 2,4,5-T, this order is nearly the same only with an exception that the late two kinds of starch are similar. It is also demonstrated that herbicides with different water solubility show different release rates, no matter what type of starch is used as the matrices. | ZHU Zhifeng YU Cuiyun WANG Liping | 2006 | Wuhan University Journal of Natural Sciences2006，11，2： | 2 |
| 10 | An integrated measurement system of micro motions for MEMS dynamic performance analysis显示文摘 | Li Dachao Feng Yalin Jin Shijiu Jin Cuiyun Hao Yilong Zhang Dacheng | 2002 | 2nd International Symposium on Instrumentation Science and Technology Jinnan China Aug18~222002，，： | 1 |
| 11 | Free volume hole size of cyanate ester resin/epoxy resin interpenetrating networks and its correlations with physical properties 显示文摘 | Minfeng Zeng Cuiyun Lu | 2010 | Radiation Physics and Chemistry2010，79，： | 1 |
| 12 | The permeability effect of microcystin-RR on Escherichia coli and Bacillus subtilis显示文摘Microcystins are a kind of cyclic hepatoxins produced by many species of cyanobacteria.Most previous work have been done on the toxic effects of microcystins on animals and plants.However,the reports about the effect of microcystins on microbial cells are very limited.In this work,the permeability of MC-RR on the cell outer membrane of Escherichia coli(E.coli) and Bacillus subtilis(B.subtilis) was discussed.The permeability effect of MC-RR on the cell outer membrane of E.coli and B.subtilis under different concentrations was demonstrated by a rapid and sustained reduction in the A675 values of lysozyme-treated cells.The decrease of the absorbance values showed a time-and dose-effect.The extravasations of protein and carbonhydrate increased with the increment of the treated-concentration of MC-RR.The results showed that MC-RR could increase the permeability of cell outer membranes of E.coli and B.subtilis.The synergistic effects of MC-RR and lysozyme on bacteria indicated that MC-RR might play an ecological role in bacteria in combination with other substances in some aquatic environments. | YANG CuiYun XIA ChuanHai ZHOU ShiWei LIU YongDing | 2010 | Chinese Science Bulletin2010，55，18： | 1 |
| 13 | Sound absorption characteristics of a high-temperature sintering porous ceramic material显示文摘 | Duan Cuiyun Cui Guang Xu Xinbang Liu Peisheng | 2012 | Applied Acoustics2012，，9： | 1 |
| 14 | A modification to the Soil Conservation Service curve number method for steep slops in the Loess Plateau of China 显示文摘 | Mingbin Huang Jacques Gallichand Cuiyun Dong | 2006 | Hydrological Processes2006，20，： | 1 |
| 15 | Use of soil moisture data and curve number method for estimating runoff in the Loess Plateau of China显示文摘 | Mingbin Huang Jacques Gallichand Cuiyun Dong | 2007 | Hydrological Processes2007，21，： | 1 |
| 16 | Transcriptome analysis to identify candidate genes related to chlorogenic acid biosynthesis during development of Korla fragrant pear in Xinjiang显示文摘Korla fragrant pear(KFP)with special fragrance is a unique cultivar in Xinjiang,China.In order to explore the biosynthesis molecular mechanism of chlorogenic acid(CGA)in KFP,the samples at different development periods were collected for transcriptome analysis.High performance liquid chromatography analysis showed that CGA contents of KFP at 88,118 and 163 days after full bloom were(20.96±1.84),(12.01±0.91)and(7.16±0.41)mg/100 g,respectively,and decreased with the fruit development.Pears from these typical 3 periods were selected for de novo transcriptome assemble and 68059 unigenes were assembled from 444037960 clean reads.One‘phenylpropanoid biosynthesis’pathway including 57 unigenes,11 PALs,1 PTAL,64CLs,9 C4Hs,25 HCTs and 5 C3’Hs related to CGA biosynthesis was determined.It was found that the expression levels of 11 differentially expressed genes including 1 PAL,2 C4Hs,34CLs and 5 HCTs were consistent with the change of CGA content.Quantitative polymerase chain reaction analysis further showed that 8 unigenes involved in CGA biosynthesis were consistent with the RNA-seq data.These findings will provide a comprehensive understanding and valuable information on the genetic engineering and molecular breeding in KFP. | Hao Wen Wenqiang Wang Xi Jiang Minyu Wu Hongjin Bai Cuiyun Wu Lirong Shen | 2022 | Food Science and Human Wellness2022，11，4： | 1 |
| 17 | Sound absorption characteristics of a high-temperature sintering porous ceramic material显示文摘 | Duan Cuiyun Cui Guang Xu Xinbang | 2012 | Applied Acoustics2012，73，86： | 1 |
| 18 | A Survey on Students' Group Discussion in Conversation Class显示文摘 | Cuiyun Cai | 2005 | Sino-US English Teaching2005，2，11： | 1 |
| 19 | Free volume hole size of cyanate ester resin / epoxy resin interpenetrating networks and its correlations with physical propertie显示文摘 | Zeng Minfeng Lu Cuiyun Wang Baoyi | 2010 | Radiat Phys Chem2010，79，9： | 1 |
| 20 | Free volume hole size of Cyanate ester resin / Epoxy resin interpenetrating networks and its correlations with physical properties显示文摘 | Zeng Minfeng Lu Cuiyun Wang Baoyi | 2010 | Radiation Physics and Chemistry2010，79，9： | 1 |
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