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| 1 | Determination of scutellarin in Scutellaria barbara extract by liquid chromatography- electrochemical detection 显示文摘 | ZHANG WENZHU DI DUOLONG WEN BO | 2003 | Journal of Liquid Chromatography and Related Technologies2003，26，： | 1 |
| 2 | Preparative separation and purification of rebaudioside a from steviol glycosides using mixed-mode macroporous adsorption resins显示文摘 | LIU Yongfeng DI Duolong BAI Qingqing | | 0，，17： | 1 |
| 3 | Preparative separation and purification of rebaudioside A from steviol glycosides using mixed-mode macroporous adsorptionresins显示文摘 | LIU Yongfeng DI Duolong BA1 Qingqing | 2011 | Journal of Agricultural and Food Chemistry2011，59，17： | 1 |
| 4 | Preparative separation and purification of rebaudioside A from Stevia rebaudiana Bertoni crude extracts by mixed bed ofmacroporous adsorption resins显示文摘 | LI JIE CHEN ZHENBIN DI DUOLONG | 2012 | Food Chemistry2012，，132： | 1 |
| 5 | 显示文摘 | Lou Song Di Duolong | 2012 | J Agric Food Chem2012，60，26： | 1 |
| 6 | Preparative separation and purification of Rebaudioside A from Stevia rebaudiana Bertoni crude extracts by mixed bed of macroporous adsorption resins显示文摘 | Li Jie Chen Zhenbin Di Duolong | 2012 | Food Chemistry2012，132，： | 1 |
| 7 | Chloromethylation research of LX-1180 macroporous adsorption resin in ultrasonic environment显示文摘 | Chen Zhenbin Kang Lei Di Duolong | 2011 | Advanced Materials Research2011，，10： | 1 |
| 8 | Mechanism regulating the inhibition of lung cancer A549 cell proliferation and structural analysis of the polysaccharide Lycium barbarum显示文摘The water-soluble polysaccharide LBP-1 was isolated and characterized from Lycium barbarum L.LBP-1 was mainly composed of arabinose,galactose,glucose,xylose,mannose at a molar ratio of 37.53:28.08:14.72:7.83:4.50,respectively.Based on nuclear magnetic resonance(NMR)and methylation analysis,the backbone of LBP-1 was speculated in theα-L-Ara(1→[5-α-L-Ara(1→3)-β-D-Galp-(1→]n→4)-α-D-Galp-(1[→5-α-L-Ara(1]n[→6)-β-D-Galp-(1→4)-β-D-Galp-(1→]n,and the side chains of LBP-1 were in theα-L-Ara(1→3)-β-D-Galp-(1→6 position.These results showed that LBP-1 inhibited the growth of cancer A549 cells through cell cycle arrest and apoptosis,with an IC50 value of 42.5μg/mL.In addition,LBP-1 altered the expression of Cyclin D1,Cyclin D3,and CDK 2,thus blocking the cell cycle in G0/G1 phase,reducing cell migration,and regulating the PI3K/Akt/mTOR signaling pathway to induce apoptosis. | Wenjin Ma Yanbing Zhou Wenjin Lou Bo Wang Bing Li Xiaofen Liu Jiajun Yang Bo Yang Jianfei Liu Duolong Di | 2022 | Food Bioscience2022，47，3： | 1 |
| 9 | Polysaccharides from Enteromorpha prolifera enhance the immunity of normal mice显示文摘 | Jianteng Wei Shuxian Wang Ge Liu Dong Pei Yongfeng Liu Yi Liu Duolong Di | 2014 | International Journal of Biological Macromolecules2014，，： | 1 |
| 10 | Study on pharmacokinetics and tissue distribution of the isocorydine derivative (AICD) in rats by HPLC-DAD method显示文摘A simple and effective high-performance liquid chromatography with diode-array detection method coupled with a liquid-liquid extraction pretreatment has been developed for determining the pharmacokinetics and tissue distribution of a novel structurally modified derivative(8-acetaminoisocorydine) of isocorydine.According to the in vivo experiments data calculations by DAS 2.0 software,a two-compartment metabolic model was suitable for describing the pharmacokinetic of 8-acetaminoisocorydine in rats.8-Acetamino-isocorydine was absorbed well after oral administration,and the absolute bioavailability was 76.5%.The half-life of 8-acetamino-isocorydine after intravenous and oral administration was 2.2 h and 2.0 h,respectively.In vivo,8-acetamino-isocorydine was highly distributed in the lungs,kidney and liver;however,relatively little entered the brain,suggesting that 8-acetaminoisocorydine could not easily pass through the blood brain barrier.Our work describes the first characterization of the pharmacokinetic parameters and tissue distribution of 8-acetamino-isocorydine.The acquired data will provide useful information for the in vivo pharmacology of 8-acetaminoisocorydine,and can be applied to new drug research. | Yali Chen Qian Yan Mei Zhong Quanyi Zhao Junxi Liu Duolong Di Jinxia Liu | 2015 | Acta Pharmaceutica Sinica B2015，5，3： | 0 |
| 11 | Effects of Different Wall-breaking Methods on Extraction of Solanesol from Stems and Leaves of Potato显示文摘In order to extract solanesol from potato stems and leaves more effectively and improve the extraction rate of solanesol,the same batch of potato stems and leaves harvested from Guyuan,Ningxia was selected as a research object,cell wall of potato stems and leaves was broken by enzymolysis with cellulase and high-speed shearing,and then reflux-extracted with 95% ethanol.Solanesol content was determined by HPLC,and extract yield was calculated.Extract yield and solanesol extraction rate was used as an index for comparison of difference between the 2wall-breaking methods,so as to select the optimal wall-breaking method.The results showed that enzymolysis with cellulase exhibited extraction rate and extract yield of solanesol of 91.38%and 8.02%,respectively,which were better than those under high-speed shear emulsification technique.The enzymolysis wall-breaking method has the advantages of simple operation and strong feasibility. | Bingpeng WANG Jing MENG Mei GUO Xinyi HUANG Fangyuan DONG Duolong DI | 2017 | Agricultural Biotechnology2017，6，2： | 0 |
| 12 | Effect of Occupational Manganese Exposure on Uric Acid Levels in Human Urine显示文摘Objective To investigate the effect of long‐term and low‐level occupational Mn exposure on the level of uric acid (UA) in human urine.Methods In this study,65 volunteers were recruited,who were working on welding and foundry work in an plant in Gansu province,China.Additionally,29 control samples were collected from individuals who did not have any history of excessive Mn exposure.An improved high performance liquid chromatography system equipped with a diode‐array detector (HPLC‐DAD) method was developed to determine the UA level in human urine.A Spectra AA 220 Atomic Absorption Spectrophotometer (AAS) was used to measure the Mn level in the urine.Results The analytical method was validated for concentrations ranging from 3.82-45.84 μg/mL with acceptable accuracy,precision,and recovery.Overall,the UA levels of Mn exposure samples were significantly lower than that of control samples (P<0.05).Conclusion The practical method developed here is suitable for both routine monitoring of UA level in human urine and metabolism research.Long‐term and low‐level occupational Mn exposure may lead to a lower UA level in urine,and UA might be an indicator of the early stage of manganism. | SUN XiaoMing LIU YeWei WANG ZhenQuan LI HongBing LIU Yun DI DuoLong | 2011 | Biomedical and Environmental Sciences2011，24，3： | 0 |
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