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| 1 | Cetuximab and panitumumab in a patient with colon cancer and concomitant chronic skin disease:A potential beneficial effect on psoriasis vulgaris显示文摘Monoclonal antibodies against epidermal growth factor receptor(EGFR) are used in the treatment of advanced colorectal cancer. However, these agents can induce severe dermatological side effects that discourage their administration in patients with chronic dermatological disease. EGFR plays a key role in normal skin development and immunological function, and is expressed in various tissues and organs, although contrarily, it is overexpressed in psoriasis-related skin lesions. Thus, discussion is ongoing regarding the putative pathological role and therapeutic potential of this protein. We herein report on a patient with advanced colon cancer and concomitant long-standing psoriasis vulgaris who received antiEGFR antibody monotherapy as a third-line treatment for metastatic disease. One week after the initiation of treatment, the patient's skin lesions dramatically subsided and the improvement was sustained during therapy. Based on this case, we propose that anti-EGFR antibody therapy is not necessarily contraindicated in patients with psoriasis vulgaris. Moreover, the findings reaffirmed that EGFR is an important molecule in the pathology of psoriasis. | Ken Okamoto Hiromichi Maeda Takeo Shiga Mai Shiga Ken Dabanaka Kazuhiro Hanazaki Michiya Kobayashi | 2015 | World Journal of Gastroenterology2015，21，12： | 4 |
| 2 | A case with synchronous multiple liver metastases from gastric carcinoma: postoperative long-term disease-free survival显示文摘 | Masaya Munekage Takehiro Okabayashi Norihiro Hokimoto Takeki Sugimoto Hiromichi Maeda Tsutomu Namikawa Ken Dabanaka Michiya Kobayashi Keijiro Araki Kazuhiro Hanazaki | 2009 | Langenbeck’s Archives of Surgery2009，，4： | 1 |
| 3 | Multiple palmar epidermoid cysts显示文摘 | Yokogawa M Egawa K Dabanaka K | 2002 | Dermatology2002，205，4： | 1 |
| 4 | Diamine oxidase as a marker of intestinal mucosal injury and the effect of soluble di- etary fiber on gastrointestinal tract toxicity after intravenous 5 - flu- orouracil treatment in rats显示文摘 | Fukudome I Kobayashi M Dabanaka K | 2014 | Med Mol Morphol2014，47，2： | 1 |
| 5 | Diamine oxidase as a marker of intestinal mucosal injury and the effect of soluble dietary fiber on gastrointestinal tract toxicity after intravenous 5-fluorouracil treatment in rats显示文摘 | Ian Fukudome Michiya Kobayashi Ken Dabanaka Hiromichi Maeda Ken Okamoto Takehiro Okabayashi Ryoko Baba Nana Kumagai Koji Oba Mamoru Fujita Kazuhiro Hanazaki | 2014 | Medical Molecular Morphology2014，，2： | 1 |
| 6 | Pancreatic transection using a sharp hook-shaped ultrasonically activated scalpel显示文摘 | Takehrio Okabayashi Kazuhiro Hanazaki Isao Nishimori Takeki Sugimoto Ryuji Yoshioka Ken Dabanaka Michiya Kobayashi Saburo Onishi | 2008 | Langenbeck’s Archives of Surgery2008，，6： | 1 |
| 7 | Continuous Post-operative Blood Glucose Monitoring and Control Using a Closed-loop System in Patients Undergoing Hepatic Resection显示文摘 | Takehiro Okabayashi Kazuhiro Hnazaki Isao Nishimori Takeki Sugimoto Hiromichi Maeda Tomoaki Yatabe Ken Dabanaka Michiya Kobayashi Koichi Yamashita | 2008 | Digestive Diseases and Sciences2008，，5： | 1 |
| 8 | Effect of Daikenchuto (TJ-100) on abdominal bloating in hepatectomized patients显示文摘AIM: To evaluate the clinical usefulness of Daikenchuto (DKT) in hepatecomized patients. METHODS: Twenty patients were enrolled with informed consent. Two patients were excluded because of cancelled operations. The remaining 18 patients were randomly chosen for treatment with DKT alone or combination therapy of DKT and lactulose (n = 9, each group). Data were prospectively collected. Primary end points were Visual Analogue Scale (VAS) score for abdominal bloating, total Gastrointestinal Symptoms Rating Scale (GSRS) score for abdominal symptoms, and GSRS score for abdominal bloating. RESULTS: The VAS score for abdominal bloating and total GSRS score for abdominal symptoms recovered to levels that were not significantly different to preoperative levels by 10 d postoperation. Combination therapy of DKT and lactulose was associated with a significantly poorer outcome in terms of VAS and GSRS scores for abdominal bloating, total GSRS score, and total daily calorie intake, when compared with DKT alone therapy. CONCLUSION: DKT is a potentially effective drug for postoperative management of hepatectomized patients, not only to ameliorate abdominal bloating, but also to promote nutritional support by increasing postoperative dietary intake. | Kazuhiro Hanazaki Kengo Ichikawa Masaya Munekage Hiroyuki Kitagawa Ken Dabanaka Tsutomu Namikawa | 2013 | World Journal of Gastrointestinal Surgery2013，5，4： | 0 |
| 9 | Nodular fasciitis in the mesentery, a differential diagnosis of peritoneal carcinomatosis显示文摘Nodular fasciitis is a benign proliferative lesion composed of fibroblast-like cells that affects various sites in the body.We describe a patient with nodular fasciitis in the mesentery,encountered during laparotomy for the treatment of ascending colon cancer.The nodular fasciitis in our patient resembled peritoneal dissemination of malignancy on macroscopic observation.Because the treatment options change with concomitant peritoneal dissemination of gastrointestinal tract malignancy,recognition of this rare condition and preparation for unexpected nodular lesions are crucial. | Mai Shiga Ken Okamoto Manabu Matsumoto Hiromichi Maeda Ken Dabanaka Tsutomu Namikawa Sunao Uemura Masaya Munekage Michiya Kobayashi Kazuhiro Hanazaki | 2014 | World Journal of Gastroenterology2014，20，5： | 0 |
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