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| 1 | Four-sample lactose hydrogen breath test for diagnosis of lactose malabsorption in irritable bowel syndrome patients with diarrhea显示文摘AIM: To validate 4-sample lactose hydrogen breath testing(4SLHBT) compared to standard 13-sample LHBT in the clinical setting.METHODS: Irritable bowel syndrome patients with diarrhea(IBS-D) and healthy volunteers(HVs) were enrolled and received a 10 g, 20 g, or 40 g doselactose hydrogen breath test(LHBT) in a randomized, double-blinded, controlled trial. The lactase gene promoter region was sequenced. Breath samples and symptoms were acquired at baseline and every 15 min for 3 h(13 measurements). The detection rates of lactose malabsorption(LM) and lactose intolerance(LI) for a 4SLHBT that acquired four measurements at 0, 90, 120, and 180 min from the same data set were compared with the results of standard LHBT.RESULTS: Sixty IBS-D patients and 60 HVs were studied. The genotype in all participants was C/C-13910. LM and LI detection rates increased with lactose dose from 10 g, 20 g to 40 g in both groups(P < 0.001). 4SLHBT showed excellent diagnostic concordance with standard LHBT(97%-100%, Kappa 0.815-0.942) with high sensitivity(90%-100%) and specificity(100%) at all three lactose doses in both groups.CONCLUSION: Reducing the number of measurements from 13 to 4 samples did not significantly impact on the accuracy of LHBT in health and IBS-D. 4SLHBT is a valid test for assessment of LM and LI in clinical practice. | Jian-Feng Yang Mark Fox Hua Chu Xia Zheng Yan-Qin Long Daniel Pohl Michael Fried Ning Dai | 2015 | World Journal of Gastroenterology2015，21，24： | 4 |
| 2 | Pneumatosis intestinalis显示文摘 | R. Michael Boerner MD PhD Daniel B. Fried MPH David M. Warshauer MD Dr. Kim Isaacs MD PhD | 1996 | Digestive Diseases and Sciences1996，，11： | 2 |
| 3 | Prevalence and Presentation of Lactose Intolerance and Effects on Dairy Product Intake in Healthy Subjects and Patients With Irritable Bowel Syndrome显示文摘 | Jianfeng Yang Yanyong Deng Hua Chu Yanqun Cong Jianmin Zhao Daniel Pohl Benjamin Misselwitz Michael Fried Ning Dai Mark Fox | 2013 | Clinical Gastroenterology and Hepatology2013，，： | 2 |
| 4 | Peroral Endoscopic Myotomy for the Treatment of Achalasia: An International Prospective Multicenter Study显示文摘 | Daniel Von Renteln Karl–Hermann Fuchs Paul Fockens Peter Bauerfeind Melina C. Vassiliou Yuki B. Werner Gerald Fried Wolfram Breithaupt Henriette Heinrich Albert J. Bredenoord Jan F. Kersten Tessa Verlaan Michael Trevisonno Thomas R?sch | 2013 | Gastroenterology2013，，2： | 2 |
| 5 | Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2012-2013显示文摘 | Meijer A Rebelo-de-Andrade H Correia V Besselaar T Drager-Dayal R Fry A Gregory V Gubareva L Kageyama T Laekenby A Lo J Odagiri T Pere- yaslov D Siqueira M M Takashita E Tashiro M Wang D Wong S Zhang W Daniels R S Hurt A C | 2014 | An- tiviral Research2014，110，： | 1 |
| 6 | Unsupervised natural image patch learning显示文摘A metric for natural image patches is an important tool for analyzing images. An efficient means of learning one is to train a deep network to map an image patch to a vector space, in which the Euclidean distance reflects patch similarity. Previous attempts learned such an embedding in a supervised manner,requiring the availability of many annotated images. In this paper, we present an unsupervised embedding of natural image patches, avoiding the need for annotated images. The key idea is that the similarity of two patches can be learned from the prevalence of their spatial proximity in natural images. Clearly, relying on this simple principle, many spatially nearby pairs are outliers. However, as we show, these outliers do not harm the convergence of the metric learning. We show that our unsupervised embedding approach is more effective than a supervised one or one that uses deep patch representations. Moreover, we show that it naturally lends itself to an efficient self-supervised domain adaptation technique onto a target domain that contains a common foreground object. | Dov Danon Hadar Averbuch-Elor Ohad Fried Daniel Cohen-Or | 2019 | Computational Visual Media2019，5，3： | 1 |
| 7 | Imaging artificial caries under composite sealants and restorations显示文摘 | Robert S Jones Michal Staninec Daniel Fried | 2004 | Journal of Biomedical Optics2004，9，6： | 1 |
| 8 | Neurologic prognostication and bispectral index monitoring after resuscitation from cardiac arrest显示文摘 | Marion Leary David A. Fried David F. Gaieski Raina M. Merchant Barry D. Fuchs Daniel M. Kolansky Dana P. Edelson Benjamin S. Abella | 2010 | Resuscitation2010，，9： | 1 |
| 9 | Peroral Endoscopic Myotomy for the Treatment of Achalasia: An International Prospective Multicenter Study显示文摘 | Daniel Von Renteln Karl–Hermann Fuchs Paul Fockens Peter Bauerfeind Melina C. Vassiliou Yuki B. Werner Gerald Fried Wolfram Breithaupt Henriette Heinrich Albert J. Bredenoord Jan F. Kersten Tessa Verlaan Michael Trevisonno Thomas R?sch | 2013 | Gastroenterology2013，，2： | 1 |
| 10 | Factors that influence the implementation of collaborative RFID programs 显示文摘 | Jennifer L Fries Anna M Turri Daniel C Bello | 2010 | Journal of Business & Industrial Marketing2010，25，8： | 1 |
| 11 | Peroral Endoscopic Myotomy for the Treatment of Achalasia: An International Prospective Multicenter Study显示文摘 | Daniel Von Renteln Karl–Hermann Fuchs Paul Fockens Peter Bauerfeind Melina C. Vassiliou Yuki B. Werner Gerald Fried Wolfram Breithaupt Henriette Heinrich Albert J. Bredenoord Jan F. Kersten Tessa Verlaan Michael Trevisonno Thomas R?sch | 2013 | Gastroenterology2013，，2： | 1 |
| 12 | Serious complications of routine ritual circumcision in a neonate: Hydro-ureteronephrosis, amputation of glans penis, and hyponatraemia显示文摘 | Aaron Hanukoglu Lavy Danielli Zeev Katzir Arkadi Gorenstein Daniel Fried | 1995 | European Journal of Pediatrics1995，，4： | 1 |
| 13 | Comparative risks of non-prescription analgesics: a structured topic review and research priorities显示文摘 | Eric J Lavonas James F Fries Daniel E Furst Kenneth J Rothman Andy Stergachis Allen J Vaida Daniel Zelterman Kate M Reynolds Jody L Green Richard C Dart | 2012 | Expert Opinion on Drug Safety2012，，1： | 1 |
| 14 | The shared landscape: what does aesthetics have to do with ecology?显示文摘 | Paul H. Gobster Joan I. Nassauer Terry C. Daniel Gary Fry | 2007 | Landscape Ecology2007，，7： | 1 |
| 15 | Molecular monitoring of culturable bacteria from deep-sea sediment of the Nankai Trough, Leg 190 Ocean Drilling Program显示文摘 | Laurent Toffin Gordon Webster Andrew J Weightman John C Fry Daniel Prieur | 2004 | FEMS Microbiology Ecology2004，，3： | 1 |
| 16 | Service-oriented manufacturing strateg显示文摘 | FRY D DANIEL C S BROOKE A | 1994 | International Journal of Opera- tions and Production Management1994，14，10： | 1 |
| 17 | 丙咪嗪蓝联合阿霉素降低神经胶质瘤侵袭性加强化疗效果研究显示文摘神经胶质瘤的高侵袭性是导致临床化疗效果欠佳的最主要原因。胶质瘤细胞向正常组织的侵润在限制化疗药物疗效发挥的同时也增加了外科手术的复杂性。基于以上背景本次研究提出降低肿瘤细胞的侵袭性可以增加化疗效果的设想。体外研究发现丙咪嗪蓝可以通过抑制肿瘤细胞中NADPH氧化酶介导的氧自由基产生并调节肌动蛋白的表达来降低侵袭性。作者使用一种具有人脑肿瘤关键性特征的侵袭型胶质瘤大鼠作为动物模型,使用丙咪嗪蓝脂质体后,大鼠的肿瘤组织更为密实。以丙咪嗪脂质体结合阿霉素治疗作为实验组,单独使用阿霉素治疗作为对照组,结果发现实验组大鼠存活时间均超过180天,其有效比例明显高于对照组(33%)。本次研究的结果对于结合丙咪嗪与阿霉素治疗神经胶质瘤的治疗模式探讨提供了极其重要的理论支持。 | 曾勇 Jeffifer M.Munson Levi Fried Sydney A.Rowson Michael Y.Bonner Lohitash Karumbaiah Begona Diaz Sara A.Courtneidge Ulla G.Knaus Daniel J.Brat Jack L.Arbiser Ravi V.Bellamkonda | 2012 | 肿瘤药学2012，2，2： | 0 |
| 18 | 弹性回弹的补偿模拟显示文摘通常实践会跟随着理论前进。但是在板材加工领域中,若使用了技术更进一步的材料,则有可能是退步的开始,弹性回弹在这里是主要问题。板材在机械应力的作用下弹性回弹使得已经完成变形加工的工件离开了人们所希望的'位置'。有一种新的模拟技术可以解决这个问题,在模拟软件中集成了全部补偿弹性回弹所需的模块。 | Daniel Fries | 2008 | 现代制造2008，，14： | 0 |
| 19 | Front-end readout electronics system of ProtoDUNE-SP LAr TPC显示文摘Purpose As a prototype of Deep Underground Neutrino Experiment far detector,ProtoDUNE single-phase Liquid Argon(LAr)Time Projection Chamber(TPC)sits in H4 beam line at CERN to characterize detector response.It consists of 6 full-size Anode Plane Assemblies(APAs)plus 18 Cathode Plane Assembly(CPA)modules to form two 3.6-m drift regions with a total of 15,360 readout channels.To achieve a good signal-to-noise ratio with this noble liquid detector(770ton LAr),cold electronics developed at BNL for extremely low temperature(77K–89K)operation is an optimal solution,which decouples the electrode and cryostat design from the readout design.Methods With CMOS front end ASICs integrated with the TPC electrodes,the electronic noise is independent of the fiducial volume and much lower than with readout electronics at room temperature.In addition,signal digitization and multiplexing to high-speed links inside the cryostat result in large reduction in the quantity of cables and the number of cryostat penetrations,giving the designers of both the TPC and the cryostat the freedom to choose the optimum configurations.Results and conclusions By April 2018,we have successfully instrumented 6 APAs with cold electronics,and the results of the integration test before the final installation in the cryostat look very promising. | Hans-Gerd Berns Hucheng Chen Alessio D’Andragora Jack Fried Daniel Gastler S.Gao Eric Hazen Wenbin Hou Shaorui Li Feng Liu Veljko Radeka Maura Spanu Emerson Vernon Elizabeth Worcester Matthew Worcester Krithika Yethiraj Bo Yu Junbin Zhang | 2019 | Radiation Detection Technology and Methods2019，3，3： | 0 |
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