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| 1 | Sharing Clinical Trial Data: A Proposal from the International Committee of Medical Journal Editors显示文摘The International Committee of Medical Journal Editors (ICMJE) believes that there is an ethical obligation to responsibly share data generated by interventional clinical trials because participants have put themselves at risk.In a growing consensus,many funders around the world-foundations,government agencies,and industry-now mandate data sharing.Here,we outline ICMJE's proposed requirements to help meet this obligation.We encourage feedback on the proposed requirements.Anyone can provide feedback at www.icmje.org by April 18,2016. | Darren B Taichman Joyce Backus Christopher Baethge Howard Bauchner Peter W de Leeuw Jeffrey M Drazen John Fletcher Frank Frizelle Irish Groves Abraham Haileamlak Astrid James Christine Laine Larry Peiperl Anja Pinborg Peush Sahni Si-Nan Wu | 2016 | Chinese Medical Journal2016，，2： | 20 |
| 2 | 临床试验数据共享声明国际医学期刊编辑委员会统一要求显示文摘国际医学期刊编辑委员会(ICMJE)认为,由于临床试验参与者处于研究风险之中,我们有伦理义务来负责任地共享干预性临床试验产生的原始数据。2016年1月,ICMJE发表了1项关于临床试验数据共享的提案,旨在帮助创造共享去标识个体患者数据的常态化环境。迄今,应我们的反馈要求,ICMJE收到了很多来自个人和团体的意见。 | Darren B Taichman Peush Sahni Larry Peiperl Christine Laine Astrid James Sung-Tae Hong Abraham Haileamlak Laragh Gollogly Fiona Godlee Frank A Frizelle Fernando Florenzano Jeffrey M Drazen Howard Bauchner Christopher Baethge Deutsches Arzteblatt Joyce Backus 季媛媛 | 2017 | 英国医学杂志中文版2017，20，7： | 2 |
| 3 | Outcomes of submucosal(T1b) esophageal adenocarcinomas removed by endoscopic mucosal resection显示文摘AIM To investigate the outcomes and recurrences of p T1 b esophageal adenocarcinoma(EAC) following endoscopic mucosal resection(EMR) and associated treatments.METHODS Patients undergoing EMR with pathologically confirmed T1 b EAC at two academic referral centers were retrospectively identified.Patients were divided into 4 groups based on treatment following EMR:Endoscopic therapy alone(group A),endoscopic therapy with either chemotherapy,radiation or both(group B),surgicalresection(group C) or no further treatment/lost to follow-up(<12 mo)(group D).Pathology specimens were reviewed by a central pathologist.Follow-up data was obtained from the academic centers,primary care physicians and/or referring physicians.Univariate analysis was performed to identify factors predicting recurrence of EAC.RESULTS Fifty-three patients with T1 b EAC underwent EMR,of which 32(60%) had adequate follow-up ≥ 12 mo(median 34 mo,range 12-103).There were 16 patients in group A,9 in group B,7 in group C and 21 in group D.Median follow-up in groups A to C was 34 mo(range 12-103).Recurrent EAC developed overall in 9 patients(28%) including 6(38%) in group A(median:21 mo,range:6-73),1(11%) in group B(median:30 mo,range:30-30) and 2(29%) in group C(median 21 mo,range:7-35.Six of 9 recurrences were local;of the 6 recurrences,5 were treated with endoscopy alone.No predictors of recurrence of EAC were identified.CONCLUSION Endoscopic therapy of T1 b EAC may be a reasonable strategy for a subset of patients including those either refusing or medically unfit for esophagectomy. | Darren D Ballard Neel Choksi Jingmei Lin Eun-Young Choi B Joseph Elmunzer Henry Appelman Douglas K Rex Hala Fatima William Kessler John M DeWitt | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，20： | 2 |
| 4 | 临床试验数据共享声明显示文摘国际医学期刊编辑委员会(ICMJE)认为,由于临床试验参与者处于研究风险之中,我们有伦理义务来负责任地共享干预性临床试验产生的原始数据。2016年1月,ICMJE发表了一项关于临床试验数据共享的提案,旨在帮助创造共享去标识个体患者数据的常态化环境。 | Darren B Taichman Peush Sahni Anja Pinborg Larry Peiperl Christine Laine Astrid James Sung-Tae Hong Abraham Haileamlak Laragh Gollogly Fiona Godlee Frank A Frizelle Fernando Florenzano Jeffrey M Drazen Howard Bauchner Christopher Baethge Joyce Backus 季媛媛 | 2017 | 中国医院院长2017，13，16： | 2 |
| 5 | Acetyl salicylic acid (aspirin) and salieylie acid induce multiple stress toleraee in bean and tomato plants显示文摘 | Tissa S Darren T Eric B | 2000 | Plant Growth Regul2000，30，： | 1 |
| 6 | Uranium reduction by desulfovibrio desulfuricans strain G20 and a cytochrome c3 mutant 显示文摘 | Rayford B P Darren M G Barbara J R | 2002 | Applied and Environmental Microbiology2002，68，6： | 1 |
| 7 | Ligand Design and Self-Recognition: A Copper (II) Complex that Dimerizes Via Hydrogen Bonds显示文摘 | Darren J B Jason R T | 2002 | Inorganica Chimica Acta2002，341，： | 1 |
| 8 | Can Conceptual Physical Education Promote Physically Active Lifestyles?显示文摘 | Darren Dale Charles B | 1998 | Pediatric Exercise Science1998，，10： | 1 |
| 9 | Discovery,synthesis and biological evaluation of novel glucokinase activators 显示文摘 | DARREN M JOANNE A SUZANNE B | 2005 | Bioorg Med Chem Lett2005，15，8： | 1 |
| 10 | Game Theoretic Analysis of Adaptive Radar Jamming 显示文摘 | Darren J B Robin J E Bill M | 2011 | IEEE Transactions on Aerospace and Electronic Systems2011，47，2： | 1 |
| 11 | Knowledge Sourcing Methods显示文摘 | Peter H Gray Darren B Meister | | 0，，： | 1 |
| 12 | Investigation of the Use of a Stacked HPGe Detector for Improving Gamma Ray Spectra at Energies above 2MeV显示文摘 | Darren G S Derek B Klaus F | 2005 | Nucl Instrum Meth A2005，536，： | 1 |
| 13 | Neural development of selective attention and response inhibition显示文摘 | James R Booth Douglas D Burman Joel R Meyer Zhang Lei Barbara L Trommer Nicholas D Davenport Wei Li Todd B Parrish Darren R Gitelman M.Marsel Mesulam | 2003 | Neuroimage2003，，2： | 1 |
| 14 | photovoltaie technologies显示文摘 | Darren M B Matt B | 2008 | Energy policy2008，36，12： | 1 |
| 15 | The harvest information discovery and access system 显示文摘 | Bowman C M Peter B Danzig Darren R Hardy | 1995 | Computer Networks and ISDN Systems1995，28，12： | 1 |
| 16 | Emerging cytokine targets in rheumatoid arthritis显示文摘 | Darren L Asquith Iain B McInnes | 2007 | Current Opinion in Rheumatology2007，，3： | 1 |
| 17 | A microfluidic system combining acoustic and dielectrophoretic particle preconcentration and focusing显示文摘 | SURENDRA K R DARREN W B CONRAD D J | 2008 | Sensors and Actuators B:Chemical2008，130，2： | 1 |
| 18 | Acetyl salicylic acid (aspirin) and salicylic acid induce multiple stress tolerace in bean and tomato plants显示文摘 | Tissa S Darren T Eric B | 2000 | Plant Growth Regul2000，30，2： | 1 |
| 19 | Automated quantitative analysis of activator protein-2α subcellular expression in melanoma tissue microarrays correlates with survival prediction显示文摘 | AARON J B DARREN W D CARMEN T | 2005 | Cancer Res2005，65，11： | 1 |
| 20 | ZnO as a novel photonic material for the UV region 显示文摘 | Chen Y F Darren B Yao T | 2000 | Mater Sci Eng: B2000，75，23： | 1 |
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