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| 1 | Rescued virus from infectious cDNA clone of rabbit hemorrhagic disease virus is adapted to RK13 cells line显示文摘Based on the infectious full-length cDNA clone of rabbit hemorrhagic disease virus (RHDV), the in vitro transcripts are introduced into RK13 cells. 12 h later, CPE could be observed clearly, and virual antigen could also be detected by IFA. The titre of the recovered virus is 104.6/mL. Immune electron micro-scopic observation of the virus particles revealed that the particles were rotund with a diameter of about 30 nm. Besides, virus titre quantification obtained by qRT-PCR showed a correlation between time from infection and virus titre. All these results showed that we have recovered RHDV from RK13 cells by re-verse genetics technology successfully, and this would be very useful in studies of the antigenicity, virulence, pathogenesis, maturation and new type vaccines of RHDV. | LIU Guangqing NI Zheng YUN Tao ZHANG Yuying DU Qingyun SHENG Zutian LIANG Huali HUA Jionggang LI Shuangmao Chen Jianping | 2006 | Chinese Science Bulletin2006，51，14： | 9 |
| 2 | Epidemiological Characteristics of Rifampicin-Resistant Tuberculosis in Students——China,2015-2019显示文摘Summary What is already known about this topic?The number of students with tuberculosis(TB)has been increasing since 2015.However,the prevalence of rifampicin-resistant tuberculosis(RR-TB)among student population is unclear.What is added by the report?The number of students with RR-TB has significantly increased from 2015 to 2019,especially in the western region of China.The majority of patients were college students.Students with RR-TB were mainly new patients. | Wei Su Yunzhou Ruan Tao Li Xin Du Jiawen Jiang Yuying He Renzhong Li | 2021 | China CDC weekly2021，3，26： | 3 |
| 3 | ECOLOGICAL EFFECTS OF NITROGEN DEPOSITION ON URBAN FORESTS: AN OVERVIEW显示文摘The global urban area is expanding continuously,resulting in unprecedented emissions and deposition of reactive nitrogen(N)in urban environments.However,large knowledge gaps remain in the ecological effects of N deposition on urban forests that provide key ecosystem services for an increasing majority of city dwellers.The current understanding of the spatial patterns and ecological effects of N deposition in urban forests was synthesized based on a literature review of observational and experimental studies.Nitrogen deposition generally increases closer to cities,resulting in an urban hotspot phenomenon.Chemical components of N deposition also shift across urban-suburban-rural gradients,showing higher ratios of ammonium to nitrate in and around urban areas.The ecological effects of N deposition on urban forest ecosystems are overviewed with a special focus on ecosystem N cycling,soil acidification,nutrient imbalances,soil greenhouse gas emissions,tree growth and forest productivity,and plant and soil microbial diversity.The distinct effects of unprecedented N deposition on urban forests are discussed in comparison with the common effects in natural forests.Despite the existing research efforts,several key research needs are highlighted to fill the knowledge gaps in the ecological effects of N deposition on urban forests. | Enzai DU Nan XIA Yuying GUO Yuehan TIAN Binghe LI Xuejun LIU Wim DE VRIES | 2022 | Frontiers of Agricultural Science and Engineering2022，9，3： | 2 |
| 4 | Analysis of DNA methylation in different tissues of Fenneropenaeus chinensis from the wild population and Huanghai No. 1显示文摘DNA methylation plays an important role in the regulation of gene expression during biological development and tissue differentiation in eukaryotes. A methylation sensitive amplification polymorphism(MSAP) including digestion, pre-selective amplification and selective amplification was optimized to compare the levels of DNA cytosine methylation at CCGG sites in muscle, gill and hemocyte from the wild populations and the selective breeding of Huanghai No. 1 of Fenneropenaeus chinensis, respectively. Significant differences in cytosine methylation levels among three tissues in two populations were detected. The average DNA methylation ratios in muscle, gill and hemocyte of the wild population were 23.1%, 22.3% and 19.7%, while those were 21.4%, 19.6%,and 18.9% in Huanghai No. 1, respectively. The DNA methylation levels of gill from the two populations were highly significant(P<0.01), the difference of muscle was significant(P<0.05), while in hemocyte, there were no significant differences(P>0.05). DNA polymorphic methylation of gill and hemocyte between the wild population and Huanghai No. 1 varies to some extent, while those of muscle kept in a balanced degree. Furthermore,polymorphic methylation was associated with demethylation and methylation of CCGG loci. | HE Yuying DU Ying LI Jian LIU Ping WANG Qingyin LI Zhaoxia | 2015 | Acta Oceanologica Sinica2015，34，12： | 2 |
| 5 | HTR2A agonists play a therapeutic role by restricting ILC2 activation in papain-induced lung inflammation显示文摘Group 2 innate lymphoid cells(ILC2s)are a category of heterogeneous cells that produce the cytokines IL-5 and IL-13,which mediate the type 2 immune response.However,specific drug targets on lung ILC2s have rarely been reported.Previous studies have shown that type 2 cytokines,such as IL-5 and IL-13,are related to depression.Here,we demonstrated the negative correlation between the depression-associated monoamine neurotransmitter serotonin and secretion of the cytokines IL-5 and IL-13 by ILC2s in individuals with depression.Interestingly,serotonin ameliorates papain-induced lung inflammation by suppressing ILC2 activation.Our data showed that the serotonin receptor HTR2A was highly expressed on ILC2s from mouse lungs and human PBMCs.Furthermore,an HTR2A selective agonist(DOI)impaired ILC2 activation and alleviated the type 2 immune response in vivo and in vitro.Mice with ILC2-specific depletion of HTR2A(Il5^(cre/+)·Htr2a^(flox/flox)mice)abolished the DOI-mediated inhibition of ILC2s in a papain-induced mouse model of inflammation.In conclusion,serotonin and DOI could restrict the type 2 lung immune response,indicating a potential treatment strategy for type 2 lung inflammation by targeting HTR2A on ST2+ILC2s. | Zhishuo Wang Chenghua Yan Qizhen Du Yuying Huang Xuezhen Li Dan Zeng Ruizhi Mao Rama Krishna Gurram Shipeng Cheng Wangpeng Gu Lin Zhu Weiguo Fan Liyan Ma Zhiyang Ling Ju Qiu Dangsheng Li Enmei Liu Yaguang Zhang Yiru Fang Jinfang Zhu Bing Sun | 2023 | Cellular & Molecular Immunology2023，20，4： | 1 |
| 6 | Arbuscular mycorrhizal fungi associated with vegetation and soil parameters under rest grazing management in a desert steppe ecosystem显示文摘 | Bai Gegen Bao Yuying Du Guoxin | 2013 | Mycorrhiza2013，23，4： | 1 |
| 7 | Efficient Synthesis of 1, 3-Dioxanes Catalyzed by Trifluoromethanesulfonic Acid Using Formalin as Formaldehyde Source 显示文摘 | Du Yuying Tian Fuli | 2007 | Catal Commun2007，8，12： | 1 |
| 8 | Effects of cop- per addition on the in-situ synthesis of SiC particles in A1 Si-C Cu system显示文摘 | Xiaofan Du Tong Oao Yuying Wu | 2014 | Materials and Design2014，63，： | 1 |
| 9 | Cross-Modal Interaction and Integration Through Stimulus-Specific Adaptation in the Thalamic Reticular Nucleus of Rats显示文摘Stimulus-specific adaptation(SSA),defined as a decrease in responses to a common stimulus that only partially generalizes to other rare stimuli,is a widespread phenomenon in the brain that is believed to be related to novelty detection.Although cross-modal sensory processing is also a widespread phenomenon,the interaction between the two phenomena is not well understood.In this study,the thalamic reticular nucleus(TRN),which is regarded as a hub of the attentional system that contains multi-modal neurons,was investigated.The results showed that SSA existed in an interactive oddball stimulation,which mimics stimulation changes from one modality to another.In the bimodal integration,SSA to bimodal stimulation was stronger than to visual stimulation alone but similar to auditory stimulation alone,which indicated a limited integrative effect.Collectively,the present results provide evidence for independent cross-modal processing in bimodal TRN neurons. | Yumei Gong Yuying Zhai Xinyu Du Peirun Song Haoxuan Xu Qichen Zhang Xiongjie Yu | 2022 | Neuroscience Bulletin2022，38，7： | 0 |
| 10 | The introduction of cobalt element into nickel-organic framework for enhanced supercapacitive performance显示文摘Metal-organic frameworks(MOFs) as promising electrodes for supercapacitors are attracting increasing research interest. Herein, we report an effective strategy to improve the electrochemical performance of Ni-MOF for supercapacitor by introducing a secondary Co ion. The Co substitution of Ni in Ni-MOF can improve the intrinsic reactivity and stability. As a result, the bimetallic Co/Ni-MOF-1:15 with an optimal Co/Ni ratio delivers high specific capacitance(359 F/g at 0.5 A/g), good rate performance(81.5% retention at 5 A/g) and cycling stability(81% retention after 5000 cycles). These results demonstrate that the bimetallic synergistic strategy is an effective way to improve the pseudocapacitive performance of MOFs. | Xinxin Hang Rui Yang Yadan Xue Shasha Zheng Yuying Shan Meng Du Jiawei Zhao Huan Pang | 2023 | Chinese Chemical Letters2023，34，7： | 0 |
| 11 | Reproducible Abnormalities and Diagnostic Generalizability of White Matter in Alzheimer’s Disease显示文摘Alzheimer’s disease(AD)is associated with the impairment of white matter(WM)tracts.The current study aimed to verify the utility of WM as the neuroimaging marker of AD with multisite diffusion tensor imaging datasets[321 patients with AD,265 patients with mild cognitive impairment(MCI),279 normal controls(NC)],a unified pipeline,and independent site cross-validation.Automated fiber quantification was used to extract diffusion profiles along tracts.Random-effects meta-analyses showed a reproducible degeneration pattern in which fractional anisotropy significantly decreased in the AD and MCI groups compared with NC.Machine learning models using tract-based features showed good generalizability among independent site cross-validation.The diffusion metrics of the altered regions and the AD probability predicted by the models were highly correlated with cognitive ability in the AD and MCI groups.We highlighted the reproducibility and generalizability of the degeneration pattern of WM tracts in AD. | Yida Qu Pan Wang Hongxiang Yao Dawei Wang Chengyuan Song Hongwei Yang Zengqiang Zhang Pindong Chen Xiaopeng Kang Kai Du Lingzhong Fan Bo Zhou Tong Han Chunshui Yu Xi Zhang Nianming Zuo Tianzi Jiang Yuying Zhou Bing Liu Ying Han Jie Lu Yong Liu Multi-Center Alzheimer’s Disease Imaging(MCADI)Consortium | 2023 | Neuroscience Bulletin2023，39，10： | 0 |
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