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| 1 | More anxious than depressed:prevalence and correlates in a 15-nation study of anxiety disorders in people with type 2 diabetes mellitus显示文摘Background Anxiety disorder, one of the highly disabling, prevalent and common mental disorders, is known to be more prevalent in persons with type 2 diabetes mellitus (T2DM) than the general population, and the comorbid presence of anxiety disorders is known to have an impact on the diabetes outcome and the quality of life. However, the information on the type of anxiety disorder and its prevalence in persons with T2DM is limited. Aims To assess the prevalence and correlates of anxiety disorder in people with type 2 diabetes in different countries. Methods People aged 18-65 years with diabetes and treated in outpatient settings were recruited in 15 countries and underwent a psychiatric interview with the Mini-International Neuropsychiatric Interview. Demographic and medical record data were collected. Results A total of 3170 people with type 2 diabetes (56.2% women;with mean (SD) duration of diabetes 10.01 (7.0) years) participated. The overall prevalence of anxiety disorders in type 2 diabetic persons was 18%;however, 2.8% of the study population had more than one type of anxiety disorder. The most prevalent anxiety disorders were generalised anxiety disorder (8.1%) and panic disorder (5.1%). Female gender, presence of diabetic complications, longer duration of diabetes and poorer glycaemic control (HbA1c levels) were significantly associated with comorbid anxiety disorder. A higher prevalence of anxiety disorders was observed in Ukraine, Saudi Arabia and Argentina with a lower prevalence in Bangladesh and India. Conclusions Our international study shows that people with type 2 diabetes have a high prevalence of anxiety disorders, especially women, those with diabetic complications, those with a longer duration of diabetes and poorer glycaemic control. Early identification and appropriate timely care of psychiatric problems of people with type 2 diabetes is warranted. | Santosh K Chaturvedi Shayanth Manche Gowda Helal Uddin Ahmed Fahad D Alosaimi Nicola Andreone Alexey Bobrov Viola Bulgari Giuseppe Carra Gianluca Castelnuovo Giovanni de Girolamo Tomasz Gondek Nikola Jovanovic Thummala Kamala Andrzej Ki Nebojsa Lalic Dusica Lecic-Tosevski Fareed Minhas Victoria Mutiso David Ndetei Golam Rabbani Suntibenchakul Somruk Sathyanarayana Srikanta Rizwan Taj Umberto Valentini Olivera Vukovic Wolfgang Wolwer Larry Cimino Arie Nouwen Cathy Lloyd Norman Sartorius | 2019 | General Psychiatry2019，32，4： | 11 |
| 2 | Nitroglycerine effects on portal vein mechanics and oxidative stress in portal hypertension显示文摘AIM:Тo examine the effects of nitroglycerine on portal vein haemodynamics and oxidative stress in patients with portal hypertension.METHODS:Thirty healthy controls and 39 patients with clinically verified portal hypertension and increasedvascular resistance participated in the study.Liver di-ameters,portal diameters and portal flow velocities were recorded using color flow imaging/pulsed Doppler detection.Cross-section area,portal flow and index of vascular resistance were calculated.In collected blood samples,superoxide anion radical (O 2-),hydrogen per-oxide (H 2 O 2),index of lipid peroxidation (measured as TBARS) and nitric oxide (NO) as a marker of endothelial response (measured as nitrite-NO 2-) were determined.Time-dependent analysis was performed at basal state and in 10th and 15th min after nitroglycerine (sublingual 0.5 mg) administration.RESULTS:Oxidative stress parameters changed sig-nificantly during the study.H 2 O 2 decreased at the end of study,probably via O 2-mediated disassembling in Haber Weiss and Fenton reaction;O 2-increased signifi-cantly probably due to increased diameter and tension and decreased shear rate level.Consequently O 2-and H 2 O 2 degradation products,like hydroxyl radical,initi-ated lipid peroxidation.Increased blood flow was to some extent lower in patients than in controls due to double paradoxes,flow velocity decreased,shear rate decreased significantly indicating non Newtonian char-acteristics of portal blood flow.CONCLUSION:This pilot study could be a starting point for further investigation and possible implemen-tation of some antioxidants in the treatment of portal hypertension. | Andreja Vujanac Vladimir Jakovljevic Dusica Djordjevic Vladimir Zivkovic Mirjana Stojkovic Dragan Celikovic Nebojsa Andjelkovic Aleksandra Jurisic Skevin Dragan Djuric | 2012 | World Journal of Gastroenterology2012，18，4： | 7 |
| 3 | Ivabradine reduces chemokinc-induced CD4-positive Lymphocyte migration显示文摘 | Thomas W Peter B Dusica V | 2010 | Mediators Inflamm2010，2010，75： | 1 |
| 4 | Evaluation of different purification procedures for the electrochemical quantification of mussel metallothioneins显示文摘 | Erk Marijana lvankovic Dusica Raspor Biserka | 2002 | Talanta2002，57，6： | 1 |
| 5 | Association of serum bilirubin and uric acid levels changes during neuroinflammation in patients with initial and relapsed demyelination attacks显示文摘 | Srdjan Ljubisavljevic Ivana Stojanovic Slobodan Vojinovic Maja Milojkovic Olivera Dunjic Dragan Stojanov Dusica Pavlovic | 2013 | Metabolic Brain Disease2013，，： | 1 |
| 6 | Nano-engineering block copolymer aggregates for drug delivery显示文摘 | Dusica M Eisenberg A | 1999 | Colloids and Surfaces B:Biointerfaces1999，16，： | 1 |
| 7 | Long term exposure to CdTe quantum dots causes functional impairments in live ceils 显示文摘 | SUNG JC DUSICA M MANASI J | 2007 | Langmuir2007，23，4： | 1 |
| 8 | Original Article: Clinical Investigation: Short ileal segment for orthotopic neobladder: A feasibility study显示文摘 | PredragAleksic VladimirBancevic NovakMilovic BrankoKosevic Dusica MStamenkovic MenelaosKaranikolas Zoran MCampara MirkoJovanovic | 2010 | International Journal of Urology2010，，9： | 1 |
| 9 | Gold-nanoparticle-based biosensors for detection of enzyme activity显示文摘 | Eliza Hurter Dusica Maysinger | 2013 | Pharmacological Sciences2013，34，： | 1 |
| 10 | Polycaprolactone– b -poly(ethylene oxide) copolymer micelles as a delivery vehicle for dihydrotestosterone显示文摘 | Christine Allen Jeannie Han Yisong Yu Dusica Maysinger Adi Eisenberg | 2000 | Journal of Controlled Release2000，，3： | 1 |
| 11 | Long-term exposure to CdTe quantum dots causes functional impairments in live cells 显示文摘 | Sung Ju Cho Dusica Maysinger Manasi Jain | 2007 | Langrnuir2007，23，4： | 1 |
| 12 | Differences in subcellular distribution and toxicity of green and red emitting CdTe quantum dots显示文摘 | Jasmina Lovri? Hassan S. Bazzi Yan Cuie Genevieve R. A. Fortin Fran?oise M. Winnik Dusica Maysinger | 2005 | Journal of Molecular Medicine2005，，5： | 1 |
| 13 | Correlation between procalcitonin and intra-abdominal pressure and their role in prediction of the severity of acute pancreatitis显示文摘 | Mihailo Bezmarevic Darko Mirkovic Ivan Soldatovic Dusica Stamenkovic Nikola Mitrovic Nenad Perisic Ivan Marjanovic Sasa Mickovic Menelaos Karanikolas | 2012 | Pancreatology2012，，4： | 1 |
| 14 | Differences in subcellular distribution and toxicity of green and red emitting CdTe quantum dots显示文摘 | Jasmina Lovri? Hassan S. Bazzi Yan Cuie Genevieve R. A. Fortin Fran?oise M. Winnik Dusica Maysinger | 2005 | Journal of Molecular Medicine2005，，5： | 1 |
| 15 | Effect of Na2O/SiO2 mole ratio on the crystal type of zeo- lite synthesized from coal fly ash 显示文摘 | Dusica Vucinic Igor Miljanovic Aleksandrarosic | 2003 | J Serb Chem Soc2003，68，6： | 1 |
| 16 | 显示文摘 | Sung Ju Cho Dusica Maysinger Manasi Jain | 2007 | Langmuir2007，23，4： | 1 |
| 17 | C-peptide promotes lesion development in a mouse model of arteriosclerosis 显示文摘 | Dusica Vasic Nikolaus Marx Galina Sukhova | 2012 | Journal of Cellular and Molecular Medicine2012，16，4： | 1 |
| 18 | Nano-engineering block copolymer aggregates for drug delivery显示文摘 | Christine Allen Dusica Maysinger Adi Eisenberg | 1999 | Colloids and Surfaces B: Biointerfaces1999，，1： | 1 |
| 19 | The method for the seismic damage analysis of RC buildings显示文摘 | Peter Fajfar Peter Gaspersic Dusica Drobnic | 1996 | Earthquake Engineering and Structural Dynamics1996，25，： | 1 |
| 20 | Differences in subcellular distribution and toxicity of green and red emitting CdTe quantum dots显示文摘 | Jasmina Lovri? Hassan S. Bazzi Yan Cuie Genevieve R. A. Fortin Fran?oise M. Winnik Dusica Maysinger | 2005 | Journal of Molecular Medicine2005，，5： | 1 |
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