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| 1 | Preparation of hexagonal ultrathin WO3 nano-ribbons and their electrochemical performance as an anode material in lithium ion batteries显示文摘多达几测微计的 subnanometer 厚度, 25 nm 宽度,和长度的六角形的 ultrathin WO 3nano 带子(HUWNR ) 被一个 solvothermal 方法准备。同样准备的 HUWNR 成长[001 ] 方向,和主要暴露的方面是(120 ) 水晶飞机。因为他们的唯一的结构, HUWNR 在锂离子电池作为阳极材料展出好电气化学的性能。这些唯一的材料可以在许多地里被使用,这被相信。 | Chao Lian Xiaoling Xiao Zheng Chen Yuxi Liu Enyue Zhao Dingsheng Wang Chen Chen Yadong Li | 2016 | Nano Research2016,9,2: | 12 |
| 2 | Advances in COVID-19 mRNA vaccine development显示文摘To date,the coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has determined 399,600,607 cases and 5,757,562 deaths worldwide.COVID-19 is a serious threat to human health globally.The World Health Organization(WHO)has declared COVID-19 pandemic a major public health emergency.Vaccination is the most effective and economical intervention for controlling the spread of epidemics,and consequently saving lives and protecting the health of the population.Various techniques have been employed in the development of COVID-19 vaccines.Among these,the COVID-19 messenger RNA(mRNA)vaccine has been drawing increasing attention owing to its great application prospects and advantages,which include short development cycle,easy industrialization,simple production process,flexibility to respond to new variants,and the capacity to induce better immune response.This review summarizes current knowledge on the structural characteristics,antigen design strategies,delivery systems,industrialization potential,quality control,latest clinical trials and real-world data of COVID-19 mRNA vaccines as well as mRNA technology.Current challenges and future directions in the development of preventive mRNA vaccines for major infectious diseases are also discussed. | Enyue Fang Xiaohui Liu Miao Li Zelun Zhang Lifang Song Baiyu Zhu Xiaohong Wu Jingjing Liu Danhua Zhao Yuhua Li | 2022 | Signal Transduction and Targeted Therapy2022,7,4: | 5 |
| 3 | Tailoring interphase structure to enable high-rate, durable sodium-ion battery cathode显示文摘Na-based layered transition metal oxides with O_(3)-type structure have been considered to be promising cathodes for Na-ion batteries. However, the intrinsically limited Na-ion conductivity induced by the Otype Na-coordinate environment compromises their rate and cycle capability, hindering their practical application. Here, we report an interphase-structure tailoring strategy that improves the electrochemical properties of O_(3)-type layered cathodes achieved through surface coating and doping processes.Specifically, a Zr-doped interphase structure is designed in the model compound NaNi_(1/3)Mn_(1/3)Fe_(1/3)O_(2) using the ionic conductor Na_(3)Zr_(2)Si_(2)PO_(12) as the surface coating material and Zr-dopant provider. We discover that the modified NaNi_(1/3)Mn_(1/3)Fe_(1/3)O_(2)cathode shows a stable Na-storage structure as well as an enhanced rate/cycle capability. Combined with theoretical calculations, it is suggested that the superior electrochemical performances originate from the Zr-doped interphase structure, which has an enlarged Na layer spacing that forms favorable Na-ion diffusion channels. This work highlights a general material interface optimization method which opens a new perspective for fabricating high-performance electrodes for Na-ion batteries and beyond. | Na Li Shaofei Wang Enyue Zhao Wen Yin Zhigang Zhang Kang Wu Juping Xu Yoshihiro Kuroiwa Zhongbo Hu Fangwei Wang Jinkui Zhao Xiaoling Xiao | 2022 | Journal of Energy Chemistry2022,31,5: | 4 |
| 4 | High-capacity lithium-rich cathode oxides with multivalent cationic and anionic redox reactions for lithium ion batteries显示文摘Lithium-rich cathode oxides with capability to realize multivalent cationic and anionic redox reactions have attracted much attention as promising candidate electrode materials for high energy density lithium ion batteries because of their ultrahigh specific capacity. However, redox reaction mechanisms, especially for the anionic redox reaction of these materials, are still not very clear. Meanwhile, several pivotal challenges associated with the redox reactions mechanisms, such as structural instability and limited cycle life, hinder the practical applications of these high-capacity lithium-rich cathode oxides. Herein, we review the lithium-rich oxides with various crystal structures. The multivalent cationic/anionic redox reaction mechanisms of several representative high capacity lithium-rich cathode oxides are discussed, attempting to understand the origins of the high lithium storage capacities of these materials. In addition, we provide perspectives for the further development of these lithium-rich cathode oxides based on multivalent cationic and anionic redox reactions, focusing on addressing the fundamental problems and promoting their practical applications. | Enyue Zhao Xiqian Yu Fangwei Wang Hong Li | 2017 | Science China Chemistry2017,60,12: | 3 |
| 5 | Role of hypoxia-inducible-1α in hepatocellular carcinoma cells usinga Tet-on inducible system to regulate its expression in vitro显示文摘 | Zongquan Xu Enyu Liu Cheng Peng Yunguang Li Zhaobin He Chuanzong Zhao Jun Niu | 2012 | Oncology Reports2012,,2: | 1 |
| 6 | A case study of underground thermal storage in a solar-ground coupled heat pump system for residential buildings 显示文摘 | Wang Huajun Qi Chengying Wang Enyu Zhao Jun | 2009 | Renezoable Energy2009,34,: | 1 |
| 7 | Tuning anionic redox activity to boost high-performance sodium-storage in low-cost Na_(0.67)Fe_(0.5)Mn_(0.5)O_(2) cathode显示文摘Na-based layered iron-manganese oxide Na_(0.67)Fe_(0.5)Mn_(0.5)O_(2) containing only low-cost elements is a promising cathode for Na-ion batteries used in large-scale energy storage systems.However,the poor cycle stability restricts its practical application.The capacity decay of Na_(0.67)Fe_(0.6)Mn_(0.5)O_(2) mainly originates from the irreversible anionic redox reaction charge compensation due to the high-level hybridization between oxygen and iron.Herein,we rationally design a surface Ti doping strategy to tune the anionic redox reaction activity of Na_(0.67)Fe_(0.5)Mn_(0.5)O_(2) and improve its Na-storage properties.The doped Ti ions not only enlarge the Na migration spacing layer but also improve the structure stability thanks to the strong Ti-O bond.More importantly,the d0-shell electronic structure of Ti^(4+) can suppress the charge transfer from the oxidized anions to cations,thus reducing the anionic redox reaction activity and enhancing the reversibility of charge compensation.The modified Na_(0.67)Fe_(0.5)Mn_(0.5)O_(2) cathode shows a reversible capacity of 198 mA h g^(-1) and an increased capacity retention from 15% to 73% after about1 month of cycling.Meanwhile,a superior Na-ion diffusion kinetics and rate capability are also observed.This work advances the commercialization process of Na-based layered iron-manganese oxide cathodes;on the other hand,the proposed modification strategy paves the way for the design of high-performance electrode materials relying on anionic redox reactions. | Jianyue Jiao Kang Wu Na Li Enyue Zhao Wen Yin Zhongbo Hu Fangwei Wang Jinkui Zhao Xiaoling Xiao | 2022 | Journal of Energy Chemistry2022,31,10: | 1 |
| 8 | Facile molten salt synthesis of carbon-anchored TiN nanoparticles for durable high-rate lithium-ion battery anodes显示文摘Transition metal nitrides(TMNs),including titanium nitride(TiN),exhibit remarkable application prospects as anodes for durable high-rate lithium-ion batteries(LIBs).Regrettably,the absence of simple synthesis methods restricts their further development.Herein,a facile and low-cost molten salt synthesis strategy was proposed to prepare carbon-anchored TiN nanoparticles as an advanced anode material for LIBs with high rate capabilities.This nanosized TiN obtained is∼5 nm in size and well-distributed onto carbon plates,which could release a reversible capacity of∼381.5 mAh g^(−1)at 0.1 A g^(−1)after 250 cycles and∼141.5 mAh g^(−1)at 1.0 A g^(−1)after 1000 cycles.Furthermore,it was confirmed that the conversion reaction between TiN and Li-ions happened during the electrochemical reaction process,resulting in the formation of Li_(3)N and Ti.This unique microstructure attributed from TiN nanoparticles anchored by carbon could support the structural volume during cycling.This work highlights the method superiority of TiN prepared via a molten salt synthesis strategy as an anode for LIBs with impressive rate performances. | Ruijia Liu Na Li Enyue Zhao Jinkui Zhao Lingxu Yang Wenjun Wang Huijun Liu Chaoliu Zeng | 2022 | Materials Futures2022,1,4: | 1 |
| 9 | Exploring the potential of functional polymer-lipid hybrid nanoparticles for enhanced oral delivery of paclitaxel显示文摘Most biopharmaceutics classification system(BCS)class IV drugs,with poor solubility and inferior permeability,are also substrates of P-glycoprotein(P-gp)and cytochrome P450(CYP450),leading to their low oral bioavailability.The objective of this study is to explore the potential of using functional polymer-lipid hybrid nanoparticles(PLHNs)to enhance the oral absorption of BCS IV drugs.In this paper,taking paclitaxel(PTX)as a drug model,PTX-loaded PLHNs were prepared by a self-assembly method.Chitosan was selected to modify the PLHN to enhance its mucoadhesion and stability.Three P-gp inhibitors(D-α-tocopherol polyethylene glycol 1000 succinate,pluronic P123 and Solutol RHS15)were incorporated into selected PLHNs,and a CYP450 inhibitor(the extract of VBRB,BC0)was utilized to jointly promote the drug absorption.Properties of all the PLHNs were characterized systemically,including particle size,zeta potential,encapsulation efficiency,morphology,stability,in vitro drug release,mucoadhesion,in situ intestinal permeability and in vivo systemic exposure.It was found mucoadhesion of the CS-modified PLHNs was the strongest among all the formulations tested,with absolute bioavailability 21.95%.P-gp and CYP450 inhibitors incorporation further improved the oral bioavailability of PTX to 42.60%,8-fold increase compared with that of PTX itself(4.75%).Taken together,our study might shed light on constructing multifunctional PLHNs based on drug delivery barriers for better oral absorption,especially for BCS IV drugs. | Lu Qin Haiyang Wu Enyu Xu Xin Zhang Jian Guan Ruizhi Zhao Shirui Mao | 2021 | Asian Journal of Pharmaceutical Sciences2021,16,3: | 1 |
| 10 | Monitoring Molecular Dynamics with Single-Molecule Electronic Devices and Fluorescence Techniques显示文摘Monitoring the dynamics of a single molecule provides unique insights into the fundamental physical and chemical properties of individual molecules.Over the past few decades,various approaches have been developed to enable the real-time and high-resolution detection at the single-molecule level.Among them,electrical and optical methods are the most promising tools,for the reason that electrical detection offers high resolution while optical technology provides non-invasive,targeted measurement with the added benefit of visualization.In this review,we summarized the current state-of-the-art electrical and optical techniques for single-molecule measurement and discussed their applications in detecting dynamic events such as conformational isomerizations,intermolecular interactions,chemical reactions,and biomolecular activities.In addition,we discussed the challenges and opportunities in this area and proposed possible directions for future development. | Lan Yang Zhizhuo Zhang Cong Zhao Yani Huo Enyu Zhang Suhang He Chuancheng Jia Xuefeng Guo | 2023 | Chinese Journal of Chemistry2023,41,21: | 0 |