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| 1 | Comparative analysis of radiofrequency ablation and resection for resectable colorectal liver metastases显示文摘AIM:To evaluate the therapeutic efficacy of radiofrequency ablation(RFA)for resectable colorectal liver metastases(CRLM)compared with that of resection.METHODS:Between June 2004 and June 2009,we retrospectively analyzed 29 patients with resectable CRLMs;17 patients underwent RFA,and 12 underwent hepatic resection.All of the patients were informed about the treatment modalities and were allowed to choose either of them.RFA including an intraoperative approach was performed by a radiologist;otherwise,hepatic resection was performed by a surgeon.Comparative analysis of the two groups was performed,including comparisons of gender,age,and clinical outcomes,such as primary tumor stage and survival rates.RESULTS:The mean tumor size was significantly larger in the resection group(3.59 cm vs 2.02 cm,P<0.01),and the 5-year overall survival(OS)rate for all patients was 44.7%.There was no difference in the 5-year OS rates between the RFA and resection groups(37.8%vs66.7%).Univariate analysis indicated significantly lower5-year OS rates for patients with a tumor size>3cm.The 5-year disease-free survival(DFS)rates were17.6%and 22.2%in the RFA and resection groups,respectively(P=0.119).Univariate analysis revealed that in cases of male gender,age>65 years,T stage<Ⅳ,absence of lymphatic metastasis,and tumor size>3 cm,RFA resulted in significantly inferior 5-year DFS rates compared with surgical resection.CONCLUSION:Surgical resection revealed superior outcomes in the treatment of resectable CRLMs,particularly in cases with a hepatic tumor size>3 cm. | Sanghwa Ko Hongjae Jo Seongpil Yun Eunyoung Park Suk Kim Hyung-Il Seo | 2014 | World Journal of Gastroenterology2014，20，2： | 12 |
| 2 | Mitochondrial H2O2 generated from electron transport chain complex I stimulates muscle differentiation显示文摘Mitochondrial 反应的氧种类(mROS ) 被认为有害到房间。然而,他们的生理的角色一直不作为表明调停人是彻底地探索了。这里,我们调查了 mROS 是否从 mitochondrial 电子运输链(mETC ) 产生了复杂我刺激了肌肉区别。我们的结果证明 mROS 的数量被增加并且锰 superoxide dismutase (MnSOD ) 在肌肉区别期间经由 NF-B 激活被导致。指向线粒体的抗氧化剂(MitoQ 和 MitoTEMPOL ) 和指向线粒体的过氧化氢酶减少了没有影响 ATP 的数量的 mROS 数量和压制的肌肉区别。Mitochondrial 改变包括在线粒体的数字和尺寸的 mitochondrial 抄写因素 A 和增加的正式就职,并且功能的激活在肌肉区别期间被观察。特别地,增加了 mETC 建筑群的表示层次我子单元和建筑群的一项更高的活动我比另外的建筑群被观察。毒鱼藤素, mETC 建筑群的一个禁止者我,减少 mitochondrial NADH/NAD+ 比率和 mROS 层次在肌肉区别期间。mROS 铺平的我用小介入 RNA 和毒鱼藤素减少了的建筑群的抑制,压制的肌肉区别,和有伴随物的弄空的 ATP 层次在 glycolysis 增加。从这些结果,我们结束那复杂我导出 | Seonmin Lee Eunyoung Tak Jisun Lee MA Rashid Michael P Murphy Joohun Ha Sung Soo Kim | 2011 | Cell Research2011，21，5： | 4 |
| 3 | Anisotropic,Wrinkled,and Crack-Bridging Structure for Ultrasensitive,Highly Selective Multidirectional Strain Sensors显示文摘Flexible multidirectional strain sensors are crucial to accurately determining the complex strain states involved in emerging sensing applications.Although considerable efforts have been made to construct anisotropic structures for improved selective sensing capabilities,existing anisotropic sensors suffer from a trade-off between high sensitivity and high stretchability with acceptable linearity.Here,an ultrasensitive,highly selective multidirectional sensor is developed by rational design of functionally different anisotropic layers.The bilayer sensor consists of an aligned carbon nanotube(CNT)array assembled on top of a periodically wrinkled and cracked CNT-graphene oxide film.The transversely aligned CNT layer bridge the underlying longitudinal microcracks to effectively discourage their propagation even when highly stretched,leading to superior sensitivity with a gauge factor of 287.6 across a broad linear working range of up to 100%strain.The wrinkles generated through a pre-straining/releasing routine in the direction transverse to CNT alignment is responsible for exceptional selectivity of 6.3,to the benefit of accurate detection of loading directions by the multidirectional sensor.This work proposes a unique approach to leveraging the inherent merits of two cross-influential anisotropic structures to resolve the trade-off among sensitivity,selectivity,and stretchability,demonstrating promising applications in full-range,multi-axis human motion detection for wearable electronics and smart robotics. | Heng Zhang Dan Liu Jeng-Hun Lee Haomin Chen Eunyoung Kim Xi Shen Qingbin Zheng Jinglei Yang Jang-Kyo Kim | 2021 | Nano-Micro Letters2021，13，8： | 3 |
| 4 | Paths out of poverty:International experience显示文摘The global community has committed,as the first priority of the Sustainable Development Goals(SDGs),to end poverty in all its forms everywhere.While the decline of global poverty continues,progress has slowed and remains uneven through different parts of the world.To ensure that no one is left behind in China and beyond,research will be critical to inform paths out of poverty.In this regard,it is valuable to take stock of international experiences and the various pathways out of poverty with a focus on agriculture.Africa's agricultural growth has been largely driven by land expansion and poverty reduction has been the slowest among all regions.South Asia agriculture has been led by diversification of smallholder agriculture and its poverty reduction impact has been large,but its future poverty reduction is limited by rural–urban migration and lack of formal jobs in urban centers.Social protection programs have been used by many Latin American countries as the region is more urbanized than any other developing regions.China's agricultural and economic success was driven by agriculture-led reforms and rural development.These changes brought significantly higher incomes among rural residents,which accounted for highest initial levels of poverty and hunger,and in increased availability of food at affordable prices.Investments in nutrition,health,education,clean water,and good sanitation also complemented progress.The foremost lesson is that smallholder-led agriculture growth in land scarce countries often have the largest impact on poverty reduction.Secondly,nonfarm employment and rural–urban migration must follow once agricultural productivity has reached a certain level.However,premature exiting from agriculture can do more harm.Thirdly,even before large scale poverty reduction through sectoral and regional development is exhausted,social safety nets must be established to cover those who have not benefited from growth and development.Productive social safety nets have proven to be cost-effective in many countries.Urban poverty should also be part of the protection scheme when large proportion of rural population moves to cities. | FAN Sheng-gen Emily EunYoung CHO | 2021 | Journal of Integrative Agriculture2021，20，4： | 2 |
| 5 | Overcoming the obstacles of current photodynamic therapy in tumors using nanoparticles显示文摘Photodynamic therapy(PDT)has been applied in clinical treatment of tumors for a long time.However,insufficient supply of pivotal factors including photosensitizer(PS),light,and oxygen in tumor tissue dramatically reduces the therapeutic efficacy of PDT.Nanoparticles have received an influx of attention as drug carriers,and recent studies have demonstrated their promising potential to overcome the obstacles of PDT in tumor tissue.Physicochemical optimization for passive targeting,ligand modification for active targeting,and stimuli-responsive release achieved efficient delivery of PS to tumor tissue.Various trials using upconversion NPs,two-photon lasers,X-rays,and bioluminescence have provided clues for efficient methods of light delivery to deep tissue.Attempts have been made to overcome unfavorable tumor microenvironments via artificial oxygen generation,Fenton reaction,and combination with other chemical drugs.In this review,we introduce these creative approaches to addressing the hurdles facing PDT in tumors.In particular,the studies that have been validated in animal experiments are preferred in this review over proof-of-concept studies that were only performed in cells. | Donghyun Lee Soonmin Kwon Seok-young Jang Eunyoung Park Yeeun Lee Heebeom Koo | 2022 | Bioactive Materials2022，7，2： | 2 |
| 6 | New strategy for reversal tolerant anode for automotive polymer electrolyte fuel cell显示文摘Since the commercialization of the fuel cell electric vehicles (FCEVs), the polymer electrolyte membrane fuel cell system has been actively improved as a powertrain for ultimate environment-friendly vehicle. During the FCEV operation, various transient conditions such as start-up/shut-down and fuel starvation occur irregularly, which deteriorates the durability of the membrane electrode assembly. In particular, when fuel starvation occurs, the carbon support in the anode is oxidized within few minutes, thus the mitigation of this phenomenon is essential for securing the durability. This short review introduces the concept of reversal tolerant anode (RTA), which is a mitigation method using an oxygen evolution catalyst and reviews some previous reports. In addition, new approach for RTA suggested by authors recently, which is the replacement of Pt anode catalyst by multifunctional IrRu alloy catalyst that simultaneously exhibits the activities for the hydrogen oxidation reaction and the oxygen evolution reaction is introduced. | Chanho Pak Seung Woo Lee Chaekyung Baik Bong Ho Lee Dae Jong You Eunyoung You | 2019 | Chinese Chemical Letters2019，30，6： | 2 |
| 7 | Red meat intake and the risk of endometrial cancer:Metaanalysis of observational studies显示文摘AIM:To evaluate whether red meat intake is related to the risk of endometrial cancer(EC) using meta-analysis.METHODS:We searched Pub Med,EMBASE,and the Cochrane Library up to June 2013,using common keywords related to red meat and EC.Case-control studies and cohort studies comparing the risk of endometrial cancer among categories by the amount of intake were included.Eleven case-control studies and five cohort studies met our criteria.We performed a conventional and a dose-response meta-analysis of case-control studies using the Der Simonian-Laird method for random-effects.For cohort studies we performed a conventional meta-analysis.Publication bias was evaluated using Egger's test.RESULTS:In the meta-analysis of 11 case-control studies including 5419 cases and 12654 controls,higher red meat consumption was associated with an increased risk of EC [summary relative risk(SRR) = 1.43,95%CI:1.15-1.79;I2 = 73.3% comparing extreme intake categories).In a dose-response analysis,for red meat intake of 100 g/d,SRR was 1.84(95%CI:1.64-2.05).In contrast,in the meta-analysis of five prospective studies including a total of 2549 cases among 247746 participants,no significant association between red meat intake and EC risk(SRR = 0.97,95%CI:0.85-1.11;I2 = 4.9% comparing extreme intake categories) was observed.CONCLUSION:Our meta-analysis found a significantlinear association between red meat intake and EC risk based on case-control studies but this was not confirmed in prospective studies. | Woong Ju Na Na Keum Dong Hoon Lee Yun Hwan Kim Seung Cheol Kim Eric L Ding Eunyoung Cho | 2015 | World Journal of Meta-Analysis2015，3，2： | 2 |
| 8 | Proto-oncogenic H-Ras, K-Ras, and N-Ras are involved in muscle differentiation via phosphatidylinositol 3-kinase显示文摘Oncogenic H 地岬 G12V 和它的变体被显示了禁止肌肉区别。然而,在肌肉区别的 proto-oncogenic 地岬(c 地岬) 的角色仍然保持不清楚。地岬的活跃 GTP 固定的形式包括 Raf, phosphatidylinositol 3-kinase (PI3K ) , Ral-GDS,和播送下游的信号的另外的分子与多样的受动器为伙伴所知。我们假设那 c 地岬可以由有选择地激活 PI3K 刺激肌肉区别,为肌肉区别的一个重要调停人。在我们的实验,由 farnesyltransferase 禁止者和 H 地岬(地岬 S17N ) 的一种主导的否定形式的 c 地岬的抑制压制了肌肉区别。一致地,由 siRNAs 的 H 地岬, K 地岬,和 N 地岬击倒的个人都堵住了肌肉区别。有趣地,我们发现 c 地岬优先地与 PI3K 而非它的主要有约束力的搭挡 c-Raf 交往,在 myogenic 区别期间,与全部的 c 地岬活动仍然保持未改变。PI3K 和它的下游的 myogenic 小径, Nox2/NF-魏 B /inducible 氮的氧化物 synthase (iNOS ) 小径,被发现被 c 地岬活动的抑制在区别期间压制。而且, PI3K 的一种组成地活跃的形式的表示完全救了区别块并且在 c-Ras-inhibited 房间重新激活 Nox2/NF-魏 B /iNOS 小径。根据我们的结果,我们断定与 oncogenic 地岬相反, proto-oncogenic H 地岬, K 地岬,和 N 地岬直接经由 PI3K 和它的下游的发信号小径涉及肌肉区别的提升。另外, PI3K 小径激活与不同主要激活的 Raf/Mek/Erk 小径的并发的抑制被联系。 | Jisun Lee Kyu Jin Choi Min Jin Lim Feng Hong Tae Gyu Choi Eunyoung Tak Seonmin Lee Young-Joo Kim Sung Goo Chang Jin Man Cho Joohun Ha Sung Soo Kim | 2010 | Cell Research2010，20，8： | 2 |
| 9 | Novel antibacterial lactoferrin peptides generated by rennet digestion and autofocusing technique 显示文摘 | Hend A Elbarbary Adham M Abdou EunYoung Park | 2010 | International Dairy Journal2010，，20： | 1 |
| 10 | Leading by Leveraging Culture 显示文摘 | Chatman J A Eunyoung Cha S | 2003 | California Management Review2003，45，4： | 1 |
| 11 | Effect of a mixed solution of sodium hyaluronate and carboxymethyl cellulose on upper limb dysfunction after total mastectomy:a double-blind, randomized clinical trial显示文摘 | Eun Joo Yang Eunyoung Kang Jin Youn Jang | | 0，，： | 1 |
| 12 | Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor immune microenvironment显示文摘 | Aleksandar D. Kostic Eunyoung Chun Lauren Robertson Jonathan N. Glickman Carey Ann Gallini Monia Michaud Thomas E. Clancy Daniel C. Chung Paul Lochhead Georgina L. Hold Emad M. El-Omar Dean Brenner Charles S. Fuchs Matthew Meyerson Wendy S. Garrett | 2013 | Cell Host & Microbe2013，，： | 1 |
| 13 | Adolescent meat intake and breast cancer risk显示文摘 | FARVID M S EUNYOUNG C CHEN W Y | 2015 | International Journal of Cancer2015，136，： | 1 |
| 14 | Control and simulation of relative motion for aerial refueling in racetrack maneuvers 显示文摘 | Atilla Dogan Eunyoung Kim | 2007 | Journal of Guidance Control and Dynamics2007，30，5： | 1 |
| 15 | Time course of symptom disappearance after microvascular decompression for hemifacial spasm显示文摘 | Eun--Tak Oh Eunyoung Kim Dong--Keun Hyun et ai | 2008 | Korean Neurosurg Soc2008，44，： | 1 |
| 16 | Chitosan-g-mPEG- supported palladium (0) catalyst for Suzuki cross-couplingreaction in water显示文摘 | Sin Eunyoung Yi Song Se Lee Yoon Sik | 2010 | Journal of Molecular Catalysis A: Chemica2010，315，1： | 1 |
| 17 | Effect of chemical etching by sulfuric acid or H 2 O 2 –NH 3 mixed solution on the photocatalytic activity of rutile TiO 2 nanorods显示文摘 | Eunyoung Bae Naoya Murakami Misa Nakamura Teruhisa Ohno | 2010 | Applied Catalysis A, General2010，，： | 1 |
| 18 | ABO blood group and risk of renal cell cancer显示文摘 | Hee-Kyung Joh Eunyoung Cho Toni K. Choueiri | 2012 | Cancer Epidemiology2012，，6： | 1 |
| 19 | Network connectivity with a family of group mobility models显示文摘 | La R J Eunyoung Seo | 2012 | Mobile Computing2012，11，3： | 1 |
| 20 | Paraquat intoxication in Korea显示文摘 | Hwang Kyuyoon Lee Eunyoung Hong saeyong | 2002 | Arch Environ Health2002，57，2： | 1 |
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