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32篇 您的检索式：作者名="Fabienne S"

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	题名	作者	年代	出处	被引量
1	Frequent mutations of the CA simple sequence repeat in intron 1 of EGFR in mismatch repair-deficient colorectal cancers显示文摘AIM:To investigate the polymorphic simple sequencerepeat in intron 1 of the epidermal growth factor receptorgene(EGFR)(CA-SSRⅠ),which is known to affect theefficiency of gene transcription as a putative target of themismatch repair(MMR)machinery in colorectal tumors.METHODS:The CA-SSRⅠgenotype was analyzed ina total of 86 primary colorectal tumors,selected upontheir microsatellite instability(MSI)status[42 with highfrequency MSI(MSI-H)and 44 microsatellite stable(MSS)]and their respective normal tissue.The effect of the CA-SSRⅠgenotype on the expression of the EGFR gene wasevaluated in 18 specimens using quantitative real-timereverse transcription PCR and immunohistochemistry.RESULTS:Mutations in CA-SSRⅠwere detected in 86%(36 of 42)of MSI-H colorectal tumors and 0%(0 of 44)ofMSS tumors,indicating the EGFR gene as a novel putativespecific target of the defective MMR system(P<0.001).Impaired expression of EGFR was detected in most ofthe colorectal tumors analyzed[6/12(50%)at the mRNAlevel and 15/18(83%)at the peptide level].However,noassociation was apparent between EGFR expression andCA-SSRⅠstatus in tumors or normal tissues.CONCLUSION:Our results suggest that CA-SSRⅠsequence does not contribute to the regulation of EGFRtranscription in colon,and should thus not be consideredas a promising predictive marker for response to EGFRinhibitors in patients with colorectal cancer.	Marie-Pierre Buisine Agnès Wacrenier Christophe Mariette Emmanuelle Leteurtre Fabienne Escande Sana Aissi Amandine Ketele Annette Leclercq Nicole Porchet Thécla Lesuffleur	2008	World Journal of Gastroenterology2008，14，7：	3
2	BCL9 is an essential component of canonical Wnt signaling that medi- ates the differentiation of myogenic progenitors during muscle regeneration显示文摘	ANDREW S B FABIENNE M S JASMINE H et ol	2009	Developmental Biology2009，335，1：	1
3	The collection of NFATcl-dependent transcripts in the osteoclast includes nuerous genes non -essential to physiologic bone resorption 显示文摘	Julia F Fabienner Coury Rosalyn S	2012	Bone2012，51，：	1
4	Detection of multiple noroviruses associated with an international gastroenteritis outbreak linked to oyster consumption显示文摘	Le GuyaderFrancoise S Bon Fabienne DeMedici Dario	2006	J Clin Microbiol2006，44，11：	1
5	A MYB Transcription Factor Regulates Very-Long-Chain Fatty Acid Biosynthesis for Activation of the Hypersensitive Cell Death Response in Arabidopsis(W)(OA)显示文摘	Raffaele Sylvain Vailleau Fabienne Léger Amandine Joubès Jér?me Miersch Otto Huard Carine Blée Elisabeth Mongrand Sébastien Domergue Frédéric Roby Dominique	2008	Plant Cell2008，，3：	1
6	Direct evidence for ribonucleolytic activity of a PR-10-like protein from white lupin roots显示文摘	Brigitte Bantignies Jacynthe Séguin Ingrid Muzac Fabienne Dédaldéchamp Patrick Gulick Ragai Ibrahim		0，2000，：	1
7	Liver Transplantation for Hepatocellular Carcinoma: A Model Including α-Fetoprotein Improves the Performance of Milan Criteria显示文摘	Christophe Duvoux Fran?oise Roudot–Thoraval Thomas Decaens Fabienne Pessione Hanaa Badran Tullio Piardi Claire Francoz Philippe Compagnon Claire Vanlemmens Jérome Dumortier Sébastien Dharancy Jean Gugenheim Pierre–Henri Bernard René Adam Sylvie Radenne Fa	2012	Gastroenterology2012，，4：	1
8	A new simplified acute hysiology score (SAPS Ⅱ ) based on a European/North Americian multicenter study 显示文摘	Jean-Roger LG Stanley L Fabienne S	1993	JAMA1993，270，24：	1
9	Hla types in celiac disease patients not carrying the DQA105-DQB102 (DQ2) heterodimer: results from the european genetics cluster on celiac disease显示文摘	Kati Karell Andrew S Louka Simon J Moodie Henry Ascher Fabienne Clot Luigi Greco Paul J Ciclitira Ludvig M Sollid Jukka Partanen	2003	Human Immunology2003，，4：	1
10	Tumor-infiltratingFoxP3+ regulatory cells show strong prognostic signifi-cance in colorectal cancer显示文摘	Paul S Michael P Fabienne G	2009	J Clin Oncol2009，27，2：	1
11	Nanomorphology and Reaction to Fire of Polyurethane and Polyamide Nanocomposites Containing Flame Retardants显示文摘	Serge B Fabienne S Thomas T	2010	Polymer Degradation and Stability2010，95，3：	1
12	BTG/TOB factors impact deadenylases显示文摘	Fabienne Mauxion Chyi-Ying A. Chen Bertrand Séraphin Ann-Bin Shyu	2009	Trends in Biochemical Sciences2009，，12：	1
13	Isogene specific oligo arrays reveal multifaceted changes in gene expression during grape berry (Vitis vinifera L.) development显示文摘	Nancy Terrier David Glissant Jér?me Grimplet Fran?ois Barrieu Philippe Abbal Carole Couture Agnès Ageorges Rossitza Atanassova Céline Léon Jean-Pierre Renaudin Fabienne Dédaldéchamp Charles Romieu Serge Delrot Sa?d Hamdi	2005	Planta2005，，5：	1
14	Direct evidence for ribonucleolytic activity of a PR-10-like protein from white lupin roots显示文摘	Brigitte Bantignies Jacynthe Séguin Ingrid Muzac Fabienne Dédaldéchamp Patrick Gulick Ragai Ibrahim	2000	Plant Molecular Biology2000，，6：	1
15	Long-term organic farming fosters below and aboveground biota: Implications for soil quality, biological control and productivity显示文摘	Klaus Birkhofer T. Martijn Bezemer Jaap Bloem Michael Bonkowski S?ren Christensen David Dubois Fleming Ekelund Andreas Flie?bach Lucie Gunst Katarina Hedlund Paul M?der Juha Mikola Christophe Robin Heikki Set?l? Fabienne Tatin-Froux Wim H. Van der Putten	2008	Soil Biology and Biochemistry2008，，9：	1
16	Crossed Characterisation of Polymer-layered Silicate (PLS) Nanocomposite Morphology: TEM, X- ray Diffraction, Rheology and Solid-state Nuclear Magnetic Resonance Measurement 显示文摘	Fabienne S Bourbigot S	2008	European Polymer Journal2008，，44：	1
17	Characterization of the Bystander Effect of Somatostatin Receptor sst2 After In Vivo Gene Transfer into Human Pancreatic Cancer Cells 显示文摘	Nicolas C Fabienne V Anny S	2005	Human Gene Therapy2005，16，10：	1
18	Norwalk virus-specific binding to oyster digestive tissues显示文摘	Le Guyader Francoise S Loisy Fabienne Atmar Robert L	2006	Emerg Infect Dis2006，12，6：	1
19	Magnesium deficiency in sugar beets alters sugar partitioningand phloem loadingin youngmature leaves 显示文摘	Christian H Fabienne B Mireille F Reto J S Serge D Nathalie V	2005	Planta2005，220，：	1
20	Passive leg raising is predictive of fluid responsiveness in spontaneously breathing patients with severe sepsis or acute pancreatitis显示文摘	Sébastien Préau Fabienne Saulnier Florent Dewavrin Alain Durocher Jean-Luc Chagnon	2010	Critical Care Medicine2010，，3：	1

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