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| 1 | Summer atmospheric boundary layer structure in the hinterland of Taklimakan Desert, China显示文摘Understanding the characteristics of the structure of desert atmospheric boundary layer and its land surface process is of great importance to the simulations of regional weather and climate.To investigate the atmospheric boundary layer structure and its forming mechanism of Taklimakan Desert,and to improve the accuracy and precision of regional weather and climate simulations,we carried out a GPS radiosonde observation experiment in the hinterland of Taklimakan Desert from 25 June to 3 July,2015.Utilizing the densely observed sounding data,we analyzed the vertical structures of daytime convective boundary layer and nighttime stable boundary layer in summer over this region,and also discussed the impacts of sand-dust and precipitation events on the desert atmospheric boundary layer structure.In summer,the convective boundary layer in the hinterland of Taklimakan Desert developed profoundly and its maximum height could achieve 4,000 m;the stable boundary layer at nighttime was about 400–800-m thick and the residual mixing layer above it could achieve a thickness over 3,000 m.Sand-dust weather would damage the structures of nighttime stable boundary layer and daytime convective boundary layer,and the dust particle swarm can weak the solar radiation absorbed by the ground surface and further restrain the strong development of convective boundary layer in the daytime.Severe convective precipitation process can change the heat from the ground surface to the atmosphere in a very short time,and similarly can damage the structure of desert atmospheric boundary layer remarkably.Moreover,the height of atmospheric boundary layer was very low when raining.Our study verified the phenomenon that the atmospheric boundary layer with supernormal thickness exists over Taklimakan Desert in summer,which could provide a reference and scientific bases for the regional numerical models to better represent the desert atmospheric boundary layer structure. | WANG Minzhong WEI Wenshou HE Qing YANG Yuhui FAN Lei ZHANG Jiantao | 2016 | Journal of Arid Land2016，8，6： | 17 |
| 2 | High-density genetic map construction and identification of loci controlling flower-type traits in Chrysanthemum(Chrysanthemum×morifolium Ramat.)显示文摘Flower type is an important and extremely complicated trait of chrysanthemum.The corolla tube merged degree(CTMD)and the relative number of ray florets(RNRF)are the two key factors affecting chrysanthemum flower type.However,few reports have clarified the inheritance of these two complex traits,which limits directed breeding for flower-type improvement.In this study,305 F1 hybrids were obtained from two parents with obvious differences in CTMD and RNRF performance.Using specific-locus amplified fragment sequencing(SLAF-seq)technology,we constructed a high-density genetic linkage map with an average map distance of 0.76 cM.Three major QTLs controlling CTMD and four major QTLs underlying RNRF were repeatedly detected in the 2 years.Moreover,the synteny between the genetic map and other Compositae species was investigated,and weak collinearity was observed.In QTL regions with a high degree of genomic collinearity,eight annotated genes were probed in the Helianthus annuus L.and Lactuca sativa L.var.ramosa Hort.genomes.Furthermore,20 and 11 unigenes were identified via BLAST searches between the SNP markers of the QTL regions and the C.vestitum and C.lavandulifolium transcriptomes,respectively.These results lay a foundation for molecular marker-assisted breeding and candidate gene exploration in chrysanthemum without a reference assembly. | Xuebin Song Yuhui Xu Kang Gao Guangxun Fan Fan Zhang Chengyan Deng Silan Dai He Huang Huaigen Xin Yingying Li | 2020 | Horticulture Research2020，7，1： | 5 |
| 3 | Reversing cold tumors to hot: An immunoadjuvant-functionalized metalorganic framework for multimodal imaging-guided synergistic photoimmunotherapy显示文摘Immunotherapy assays using immunoadjuvants and tumor antigens could greatly increase the survival rates of patients with malignant tumors.As effective carriers,metal-organic frameworks(MOFs)have been widely utilized in cancer therapy due to their remarkable histocompatibility and low toxicity.Herein,we constructed a multimodal imaging-guided synergistic cancer photoimmunotherapy by employing a specific MOF(MIL101-NH2)as the core carrier;the MOF was dual-dressed with photoacoustic and fluorescent signal donors(indocyanine green,ICG)and immune adjuvants(cytosine-phosphate-guanine sequence,CpG)and named ICGCpG@MOF.This nanocarrier could passively target the tumor site through the EPR effect and achieve multimodal imaging(fluorescence,photoacoustic,photothermal and magnetic resonance imaging)of the tumor.Synergistic cancer photoimmunotherapy was achieved via simultaneous photodynamic and photothermal methods with 808 nm laser irradiation.ICG-CpG@MOF achieved the GSH-controlled release of immunoadjuvant into the tumor microenvironment.Furthermore,the released tumor-associated antigen along with CpG could induce the transformation of tumor cells from cold to hot by activating the immune system,which significantly enhanced tumor cytotoxicity and achieved high cure rates with minimal side-effects.This strategy utilizing multimodal imaging and synergistic cancer photoimmunotherapy provides a promising approach for the diagnosis and treatment of cancer. | Zhijin Fan Hongxing Liu Yaohua Xue Jingyan Lin Yu Fu Zhaohua Xia Dongming Pan Jian Zhang Kun Qiao Zhenzhen Zhang Yuhui Liao | 2021 | Bioactive Materials2021，6，2： | 4 |
| 4 | Monitoring of SiC MOSFET Junction Temperature with On-state Voltage at High Currents显示文摘A junction temperature monitoring method has been presented based on the on-state voltage at high currents.With a simplified physical model,this method mapped the relationship between junction temperature and on-state voltage.The tough calibration and signal sensing issues are solved.Verified by body-diode voltage detecting method,the presented method shows a good performance and high accuracy,in the meantime,it would not change the modulation strategy and topology of the converter. | Dan Zheng Yuhui Kang Han Cao Xiaoguang Chai Tao Fan Puqi Ning | 2020 | Chinese Journal of Electrical Engineering2020，6，3： | 3 |
| 5 | Treatment Methods for the Quality Improvement of Recycled Concrete Aggregate (RCA)–A Review显示文摘For the purpose of providing references for further research and practical application about the quality improvement of RCA,in this paper,various treatment methods were firstly classified into four categories:removing old mortar (OM),strengthening OM,multi-stage mixing methods,and combination methods.Thereafter,the improvement mechanisms and important conclusions of various treatment methods were elucidated and summarised respectively.In the section of discussion,the improved effects as well as advantages and disadvantages of various treatment methods were compared and discussed respectively,and recommendations for the selection of treatment methods were proposed.Finally,the further research directions were pointed out,and an integrative programme on the quality improvement of RCA was recommended. | 丁亚红 WU Jun 徐平 ZHANG Xianggang FAN Yuhui | 2021 | Journal of Wuhan University of Technology(Materials Science)2021，36，1： | 3 |
| 6 | An overview of study on recycled aggregate concrete in China (1996–2011)显示文摘 | Jianzhuang Xiao Wengui Li Yuhui Fan Xiao Huang | 2011 | Construction and Building Materials2011，，： | 1 |
| 7 | Changes in the pharmacokinetics of glibenclamide in rats with streptozotocin-induced diabetes mellitus显示文摘The aim of this study was to investigate the pharmacokinetics of glibenclamide(Gli)administrated orally and intravenously to normal and diabetic rats.The AUC(0–720 min)of orally administered Gli in diabetic rats(321.24 mg min/L)was greater than that(57.752 mg min/L)in normal rats.CL(0.019 L/min/kg)was significantly slower than that(0.092 L/min/kg)of normal rats.The AUC(0–480min)of intravenous Gli in diabetic rats(1528.280 mg min/L)also was significantly greater than that(509.523 mg min/L)in normal rats,and CL was decreased approximately 3-fold.No significant difference in intestinal absorption of Gli was observed between normal and diabetic rats as determined by in situ single-pass intestinal perfusion.The clearance of Diclofenac(a substrate of CYP2C9)was determined to evaluate changes in hepatic drug-metabolizing enzyme activity in rats.The CL in diabetic rats was significantly lower(42.43%decrease)than that in normal rats.Hepatic protein expression of CYP2C9 was measured using Western blot analysis;compared with normal rats,the hepatic protein expression of CYP2A9 was decreased in diabetic rats.Therefore,the slower clearance of Gli in diabetic rats can be attributed primarily to the lower expression of hepatic CYP2C9. | Yuqing Li Yuhui Wei Fan Zhang Dan Wang Xinan Wu | 2012 | Acta Pharmaceutica Sinica B2012，2，2： | 1 |
| 8 | A haplotype map of genomic variations and genome-wide association studies of agronomic traits in foxtail millet(Setaria italica)显示文摘 | Guanqing Jia Xuehui Huang Hui Zhi Yan Zhao QiangZhao Wenjun Li Yang Chai Lifang Yang Kunyan Liu Hengyun Lu Chuanrang Zhu Yiqi Lu Congcong Zhou Danlin Fan Qijun Weng Yunli Guo Tao Huang LeiZhang Tingting Lu Qi Feng Hangfei Hao HongkuanLiu Ping Lu Ning Zhang Yuhui Li Erhu Guo ShujunWang Suying Wang Jinrong Liu Wenfei Zhang GuoqiuChen Baojin Zhang Wei Li Yongfang Wang HaiquanLi Baohua Zhao Jiayang Li Xianmin Diao Bin HanJia | 2013 | Nature Genetics2013，45，8： | 1 |
| 9 | Group information guided ICA for fMRI data analysis显示文摘 | Du Yuhui Fan Yong | | 0，，1： | 1 |
| 10 | An overview of study on recycled aggregate concrete in China (1996-2011)显示文摘 | XIAO Jianzhuang LI Wengui FAN Yuhui | 2012 | Construction and Building Materials2012，31，6： | 1 |
| 11 | A P2P botnet detection method used on-line monitoring and off-line detection显示文摘 | Fan Yuhui Xu Ning | 2014 | International Journal of Secu- rity and its Applications2014，8，3： | 1 |
| 12 | An overview of study on recycled aggregate concrete in China (1996–2011)显示文摘 | Jianzhuang Xiao Wengui Li Yuhui Fan Xiao Huang | 2011 | Construction and Building Materials2011，，： | 1 |
| 13 | Intra-host Ebola viral adaption during human infection显示文摘The onsite next generation sequencing(NGS)of Ebola virus(EBOV)genomes during the 2013–2016 Ebola epidemic in Western Africa provides an opportunity to trace the origin,transmission,and evolution of this virus.Herein,we have diagnosed a cohort of EBOV patients in Sierra Leone in 2015,during the late phase of the outbreak.The surviving EBOV patients had a recovery process characterized by decreasing viremia,fever,and biochemical parameters.EBOV genomes sequenced through the longitudinal blood samples of these patients showed dynamic intra-host substitutions of the virus during acute infection,including the previously described short stretches of 13 serial TNC mutations.Remarkably,within individual patients,samples collected during the early phase of infection possessed Ts at these nucleotide sites,whereas they were replaced by Cs in samples collected in the later phase,suggesting that these short stretches of TNC mutations could emerge independently.In addition,up to a total of 35 nucleotide sites spanning the EBOV genome were mutated coincidently.Our study showed the dynamic intra-host adaptation of EBOV during patient recovery and gave more insight into the complex EBOV-host interactions. | William JLiu Weifeng Shi Wuyang Zhu Cong Jin Shumei Zou Ji Wang Yuehua Ke Xiaofeng Li Mi Liu Tao Hu Hang Fan Yigang Tong Xiang Zhao Wenbin Chen Yuhui Zhao Di Liu Gary Wong Chengchao Chen Chunyu Geng Weiwei Xie Hui Jiang Idrissa Laybor Kamara Abdul Kamara Matt Lebby Brima Kargbo Xiangguo Qiu Yu Wang Xiaofeng Liang Mifang Liang Xiaoping Dong Guizhen Wu George F.Gao Yuelong Shu | 2019 | Biosafety and Health2019，1，1： | 1 |
| 14 | Group information guided ICA for fMRI data analysis 显示文摘 | Du Yuhui Fan Yong | 2013 | Neurolmage2013，69，1： | 1 |
| 15 | A novel highly acidic β-mannanase from the acidophilic fungus Bispora sp. MEY-1: gene cloning and overexpression in Pichia pastoris显示文摘 | Huiying Luo Yaru Wang Hui Wang Jun Yang Yuhui Yang Huoqing Huang Peilong Yang Yingguo Bai Pengjun Shi Yunliu Fan Bin Yao | 2009 | Applied Microbiology and Biotechnology2009，，3： | 1 |
| 16 | A P2P Bomet Detection Method Used On-line Monitoring and Off-line Detection 显示文摘 | Fan Yuhui Xu Ning | 2014 | International Journal of Security and Its Applications2014，8，3： | 1 |
| 17 | An overview of study on recycled aggregate concrete in China ( 1996--2011 ) 显示文摘 | XIAO Jianzhuang LI Wengui FAN Yuhui | 2012 | Construction and Building Materials2012，31，： | 1 |
| 18 | An overview of study on recycled aggregate concrete in China (1996-2011)显示文摘 | XIAO Jianzhuang LI Wengui FAN Yuhui | 2012 | Construction and Building Materials2012，31，： | 1 |
| 19 | An overview of study on recycled aggregate concrete in China ( 1996- 2011 ) 显示文摘 | XIAO Jianzhuang LI Wengui FAN Yuhui | 2012 | Construction and Building Materials2012，31，： | 1 |
| 20 | An overview of study on recycled aggregate concrete in China (1996–2011)显示文摘 | Jianzhuang Xiao Wengui Li Yuhui Fan Xiao Huang | 2011 | Construction and Building Materials2011，，： | 1 |
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