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| 1 | Serum γ-glutamyltransferase,alanine aminotransferase,and aspartate aminotransferase activity in Iranian healthy blood donor men显示文摘AIM: To determine serum γ-glutamyltransferase (GGT), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) activity, and to assess their correlation with demographic and clinical findings in healthy blood donors. METHODS: This cross-sectional study was performed in 934 male blood donors, aged 18 to 68 years, who consecutively attended Tehran blood transfusion service in 2006. All participants were seronegative for HBV or HCV infections, non alcohol users, and all underwent a standard interview and anthropometric tests. Clinical and biochemical parameters including AST, ALT, and GGT activities were determined. Patients taking drugs known to cause hepatic fat deposition were excluded. For AST, ALT, and GGT variables, we used 33.33 and 66.66 percentiles, so that each of them was divided into three tertiles. RESULTS: Mean AST, ALT, and GGT activities were 25.26 ± 12.58 U/L (normal range 5-35 U/L), 33.13 ± 22.98 (normal range 5-35 U/L), and 25.11 ± 18.32 (normal range 6-37 U/L), respectively. By univariate analyses, there were significant associations between increasing AST, ALT, or GGT tertiles and age, body weight, body mass index, and waist and hip circumferences (P < 0.05). By multiple linear regression analyses, ALT was found to be positively correlated with dyslipidemia (B = 6.988, P = 0.038), whereas ALT and AST were negatively correlated with age. AST, ALT, and GGT levels had positive correlation with family history of liver disease (B = 15.763, P < 0.001), (B = 32.345, P < 0.001), (B =24.415, P < 0.001), respectively.CONCLUSION: Although we did not determine the cutoffs of the upper normal limits for AST, ALT, and GGT levels, we would suggest screening asymptomatic patients with dyslipidemia and also subjects with a family history of liver disease. | Hossein Khedmat Farahnaz Fallahian Hassan Abolghasemi Bashir Hajibeigi Zohre Attarchi Farshid Alaeddini Mohammad Taghi Holisaz Masoumeh Pourali Shahin Sharifi Nasrin Zarei | 2007 | World Journal of Gastroenterology2007，13，6： | 7 |
| 2 | Comparative performance of different urea coating materials for slow release显示文摘Approximately 70%of the applied urea fertilizer may be lost into the environment.This loss is due to leaching,decomposition and ammonium volatilization in soil,water and air.Through coating,the slow release technology can be used to reduce losses and to increase the fertilizer efficiency.Sulfur has been used as a coating material,but the coating cracks easily because of its friability,sometimes being peeled off from the urea surface.In this study,four types of materials,namely,gypsum,cement,sulfur and zeolite,were mixed and used as coating materials to search for the most effective and cheap coating materials.The primary reasons for selecting these materials were improving fruit quality and preventing plant diseases,providing a plant nutrient,increasing soil fertility and water retention.The materials were also selected based on their availability,processiblity and price.The effects of the coating materials,thickness,drying time,sieving and sealant on the crushing strength and dissolution rate of urea were investigated.Coated urea with the same proportion of gypsum-sulfur exhibited high crushing strength and lower dissolution rate.However,the performance was further enhanced by applying molten paraffin wax on the hot urea surface.SEM images demonstrated that the micro-structure of gypsum-sulfur coated urea after sieving resulted in a smoother coated layer.The efficiency of the coated urea was improved by26%using gypsum-sulfur(20%total coating),3%paraffin wax and sieving the coating materials before application. | Khairul Ridzwan Mohd Ibrahim Farahnaz Eghbali Babadi Robiah Yunus | 2014 | Particuology2014，12，6： | 6 |
| 3 | New coating formulation for the slow release of urea using a mixture of gypsum and dolomitic limestone显示文摘 | Farahnaz Eghbali Babadi Robiah Yunus Suraya Abdul Rashid Mohamad Amran Mohd Salleh Salmiaton Ali | 2015 | Particuology2015，13，6： | 6 |
| 4 | Suppository naproxen reduces incidence and severity of post-endoscopic retrograde cholangiopancreatography pancreatitis: Randomized controlled trial显示文摘AIM: To determine the efficacy of rectally administered naproxen for the prevention of post-endoscopic retrograde cholangiopancreatography(ERCP) pancreatitis(PEP).METHODS: This double-blind randomized control trial conducted from January 2013 to April 2014 at the Gastrointestinal and Liver Diseases Research Center in Rasht, Iran. A total of 324 patients were selected from candidates for diagnostic or therapeutic ERCP by using the simple sampling method. Patients received a single dose of Naproxen(500 mg; n = 162) or a placebo(n = 162) per rectum immediately before ERCP. The overall incidence of PEP, incidence of mild to severe PEP, serum amylase levels and adverse effects were measured. The primary outcome measure was the development of pancreatitis onset of pain in the upper abdomen and elevation of the serum amylase level to > 3 × the upper normal limit(60-100 IU/L) within 24 h after ERCP. The severity of PEP was classified according to the duration of therapeutic intervention for PEP: mild, 2-3 d; moderate 4-10 d; and severe, > 10 d and/or necessitated surgical or intensive treatment, or contributed to death.RESULTS:PEP occurred in 12 %(40/324) o f participants, and was significantly more frequent in the placebo group compared to the naproxen group(P < 0.01). Of the participants, 25.9%(84/324) developed hyperamylasemia within 2 h of procedure completion, among whom only 35 cases belonged to the naproxen group(P < 0.01). The incidence of PEP was significantly higher in female sex, in patients receiving pancreatic duct injection, more than 3 times pancreatic duct cannulations, and ERCP duration more than 40 min(P s < 0.01). There were no statistically significant differences between the groups regarding the procedures or factors that might increase the risk of PEP, sphincterotomy, precut requirement, biliary duct injection and number of pancreatic duct cannulations. In the subgroup of patients with pancreatic duct injection, the rate of pancreatitis in the naproxen group was significantly lower than that in the placebo(6 patients vs 23 patients, P < 0.01, RRR = 12%, AR = 0.3, 95%CI: 0.2-0.6). Naproxen reduced the PEP in patients with ≥ 3 pancreatic cannulations(P < 0.01, RRR = 25%, AR = 0.1, 95%CI: 0.1-0.4) and an ERCP duration > 40 min(P < 0.01, RRR = 20%, AR = 0.9, 95%CI: 0.4-1.2).CONCLUSION: Single dose of suppository naproxen administered immediately before ERCP reduces the incidence of PEP. | Fariborz Mansour-Ghanaei Farahnaz Joukar Zahra Taherzadeh Homayoon Sokhanvar Tolou Hasandokht | 2016 | World Journal of Gastroenterology2016，22，21： | 4 |
| 5 | Changes induced by osmotic stress in the morphology, biochemistry, physiology, anatomy and stomatal parameters of almond species(Prunus L. spp.) grown in vitro显示文摘We investigated the influence of different levels of osmotic stress on growth and development in selected wild almond species(eight Prunus spp.) grown in vitro. The study, while endorsing the efficacy of in vitro screening of auxiliary buds of wild almond for osmotic stress tolerance, showed species variability in its response to osmotic stress. Osmotic stress reduced growth and development of all the species. However, the putative tolerant Prunus spp. showed better performance than the putative susceptible genotypes. On average there was an 80% decrease in shoot dry weight at-1.2 MPa. Reduction in shoot weight was more common in osmotic stress-susceptible species in the section labeled ‘Euamygdalus'. The tolerant Prunus species produced smaller changes in biochemical responses than the sensitive cultivars for malondialdehyde content, catalase activity, relative permeability of protoplast membranes, and net photosynthetic rate. The tolerant species maintained cell integrity better than drought sensitive species. Wild almond species in the section labeled ‘Spartioides'(Prunus arabica(Olivier) Neikle, Prunus glauca (Browicz) A.E. Murray, Prunus scoparia Spach) and ‘Lycioides'(Prunus lycioides Spach, Prunus reuteri Bossi. et Bushe) were best adapted to osmotic stress. Increase in chlorophyll concentration and leaf thickness under high osmotic stress can be considered as preliminary selection parameters for osmotic stress tolerance in Prunus spp. The study confirmed the efficacy of the in vitro method for screening of large number of genotypes for osmotic stress tolerance in wild almond species. | Shakiba Rajabpoor Soghra Kiani Karim Sorkheh Farahnaz Tavakoli | 2014 | Journal of Forestry Research2014，25，3： | 3 |
| 6 | Association of promoter polymorphism of the CD14 C (-159) T endotoxin receptor gene with chronic hepatitis B显示文摘AIM: To investigate whether single-nucleotide polymor- phisms in the promoter regions of endotoxin-responsive genes CD14 C (-159) T is associated with chronic hepatitis B. METHODS: We obtained genomic DNA from 80 patients with established diagnosis of chronic hepatitis B and 126 healthy subjects served as a control population. The CD 14 C (-159) T polymorphism was investigated using an allele specific PCR method. RESULTS: Twenty seven percent of chronic hepatitis B patients and 75% of controls were heterozygous for CT genotype. The difference between the chronic hepatitis B and control groups was statistically significant [P < 0.0001; Odds ratio (OR) = 2.887; 95% CI: 1.609-5.178]. Twenty four point six percent of chronic hepatitis B and patients 12.3% of the control group were heterozygous for TT genotype. The difference between groups was not statistically significant (P = 0.256; OR = 0.658; 95% CI: 0.319-1.358). Forty eight point four percent of chronic hepatitis B patients and 12.7% of control were homozy- gote for CC genotype (P < 0.004; OR = 0.416; 95% CI: 0.229-0.755). The frequency of allele C was 61.9% and allele T was 38.1% in hepatitis B patients group. The frequency of allele C was 55.2% and allele T was 44.8% for the control group (P = 0.179; OR = 1.319; 95% CI: 0.881-1.977). CONCLUSION: The TT heterozygous genotype was not a risk factor for chronic hepatitis B. CC homozygote genotype is protective for hepatitis B. Lack of heterozy- gosis of genotype CT is a risk factor for chronic hepatitis B. Alleles C or T were not risk factors for chronic hepatitis B. These findings show the role of a single-nucleotide polymorphism at CD14/-159 on the development ofchronic hepatitis B. Endotoxin susceptibility may play a role in the pathogenesis of chronic hepatitis B. | Amir Houshang Mohammad Alizadeh Mitra Ranjbar Mehrdad Hajilooi Farahnaz Fallahian | 2006 | World Journal of Gastroenterology2006，12，35： | 3 |
| 7 | Seven-day quintuple regimen as a rescue therapy for Helicobacter pylori eradication显示文摘AIM: To determine the efficacy of two quintupleregimens for eradication of Helicobacter pylori(H. pylori) in patients who failed previous therapies.METHODS: This prospective, open-label, randomized controlled trial was a phase Ⅱ study conducted from April 2011 to March 2012 at the Gastrointestinal and Liver Diseases Research Center in Rasht, Iran. A total of 208 patients with dyspepsia who failed previous H. pylori eradication with a ten-day quadruple therapy were enrolled. A random block method was used to assign patients to one of two treatment groups. Patients in the first group were treated with 240 mg bismuth subcitrate, 20 mg omeprazole, 1000 mg amoxicillin, 500 mg clarithromycin and 500 mg tinidazole(BOACT group). Patients in the second group received a regimen containing 240 mg bismuth subcitrate, 20 mg omeprazole, 500 mg tetracycline, 500 mg metronidazole and 200 mg ofloxacin(BOTMO group). Both regimens were given twice daily for a duration of seven days. The eradication was confirmed by a 14 C urea breath test 12 wk after completion of therapy. Patient compliance and drug side effects were evaluated at the end of the treatment period. The success rates were calculated by intention-to-treat and per-protocol analyses.RESULTS: A total of 205 patients completed the course of treatment, with three patients excluded due to drug intolerance. The mean age of patients did not differ between the BOACT and BOTMO groups(41.6 ± 12.2 years vs 39.6 ± 11.8 years), and no significant differences were found between the two groups in terms of age, sex, smoking habits or the initial eradication regimen. The intention-to-treat and perprotocol eradication rates were significantly higher in the BOTMO group(86.5%, 95%CI: 0.85-0.87 and 86.7%, 95%CI: 0.80-0.89, respectively) compared with the BOACT group(75.5%, 95%CI: 0.73-0.76 and 76%, 95%CI: 0.69-0.80, respectively)(P < 0.05). Univariate analyses for both groups did not show any association of sex, smoking and initial therapeutic regimen witheradiation rate(P > 0.05 for all). Significantly more patients experienced side effects in the BOACT group compared to the BOTMO group(77.4% vs 36.6%, P < 0.01). This difference was exemplified by increases in headache and taste disturbance(P < 0.05).CONCLUSION: Quintuple therapy with a BOTMO regimen is an alternative second-line rescue therapy for Iranian patients with failed first-line eradication treatment of H. pylori. | Fariborz Mansour-Ghanaei Farahnaz Joukar Mohammad Reza Naghipour Atena Forouhari Seyed Mohammad Seyed Saadat | 2015 | World Journal of Gastroenterology2015，21，2： | 2 |
| 8 | Comparison of Immune Responses against FMD by a DNA Vaccine Encoding the FMDV/O/IRN/2007 VP1 Gene and the Conventional Inactivated Vaccine in an Animal Model显示文摘Foot-and-mouth disease virus (FMDV) is highly contagious and responsible for huge outbreaks among cloven hoofed animals. The aim of the present study is to evaluate a plasmid DNA immunization system that expresses the FMDV/O/IRN/2007 VP1 gene and compare it with the conventional inactivated vaccine in an animal model. The VP1 gene was sub-cloned into the unique Kpn I and BamH I cloning sites of the pcDNA3.1+ and pEGFP-N1 vectors to construct the VP1 gene cassettes. The transfected BHKT7 cells with sub-cloned pEGFP-N1-VP1 vector expressed GFP-VP1 fusion protein and displayed more green fluorescence spots than the transfected BHKT7 cells with pEGFP-N1 vector, which solely expressed the GFP protein. Six mice groups were respectively immunized by the sub-cloned pcDNA3.1+-VP1 gene cassette as the DNA vaccine, DNA vaccine and PCMV-SPORT-GMCSF vector (as molecular adjuvant) together, conventional vaccine, PBS (as negative control), pcDNA3.1+ vector (as control group) and PCMV-SPORT vector that contained the GMCSF gene (as control group). Significant neutralizing antibody responses were induced in the mice which were immunized using plasmid vectors expressing the VP1 and GMCSF genes together, the DNA vaccine alone and the conventional inactivated vaccine (P<0.05). Co-administration of DNA vaccine and GMCSF gene improved neutralizing antibody response in comparison with administration of the DNA vaccine alone, but this response was the most for the conventional vaccine group. However, induction of humeral immunity response in the conventional vaccine group was more protective than for the DNA vaccine, but T-cell proliferation and IFN-γ concentration were the most in DNA vaccine with the GMCSF gene. Therefore the group that was vaccinated by DNA vaccine with the GMCSF gene, showed protective neutralizing antibody response and the most Th1 cellular immunity. | Farahnaz Motamedi Sedeh Hoorieh Soleimanjahi AmirReza Jalilian Homayoon Mahravani | 2012 | Virologica Sinica2012，27，5： | 2 |
| 9 | Knowledge about Gastric Carcinoma in North of Iran, A High Prevalent Region for Gastric Carcinoma: A Population - Based Telephone Survey 显示文摘 | Fariborz Mansour - Ghanaei Farahnaz Joukar Fatemeh Soati | 2012 | Asian Pac J Cancer Prev2012，13，7： | 1 |
| 10 | Pedestrian Self-reports of Factors Influencing the Use of Pedestrian Bridges显示文摘 | Mikko R Timo L Farahnaz A | 2007 | Accident Analysis and Prevention2007，39，： | 1 |
| 11 | Magnesium/Nano-hydroxyapatite Composite for Bone Reconstruction: The Effect of Processing Method显示文摘Nano-ceramic particles can serve as reinforcing agents for metallic materials to improve their mechanical properties.However,it is important to ensure chemical compatibility between the matrix and particles.In the present study,magnesium composites with and without nano-hydroxyapatite(nHA)particles were fabricated for bone reconstruction applications.Two different techniques were used,Conventional Sintering(CS)of powder compacts and Spark Plasma Sintering(SPS)of pre-compacted powder.Results showed that a 10 wt%addition of nHA particles to magnesium,followed by SPS improved the compression strength by 27%.CS did not lead to any significant improvement compared to SPS processing.X-ray diffraction data after CS revealed the formation of unfavorable phases due to chemical reactions between nHA particles and the magnesium matrix,while these phases were absent after SPS processing.The mechanical properties of the specimens fabricated by CS were much inferior to those processed using SPS.The shorter processing time associated with SPS leaded to reduced interaction between nHA particles and the Mg-matrix,compared to CS. | Mohammad Khodaei Farahnaz Nejatidanesh Mohammad Javad Shirani Srinivasan Iyengar Hossein Sina Omid Savabi | 2020 | Journal of Bionic Engineering2020，17，1： | 1 |
| 12 | Determination of the light-induced degradation rate of the solar cell sensitizer N719 on TiO2 nanocrystalline particles显示文摘 | FARAHNAZ N M | 2005 | Journal of Physi- cal Chemistry B2005，109，47： | 1 |
| 13 | The impact of workplace spirituality dimensions on organisational citizenship behaviour among nurses with the mediating effect of affective organisational commitment显示文摘 | Farahnaz Kazemipour Salmiah Mohd Amin | 2012 | J Nurs Manag2012，，8： | 1 |
| 14 | The effect of He-Ne and Ga-Al-As laser light on the healing of hard palate mucosa of mice显示文摘 | Farahnaz Fahimipour Mina Mahdian Behzad Houshmand Mohammad Asnaashari Alireza Naser Sadrabadi Seid Emadadin Najafi Farashah Seid Mohsen Mousavifard Arash Khojasteh | 2013 | Lasers in Medical Science2013，，1： | 1 |
| 15 | Drug delivery system for an anticancer agent, chlorogenate-Zn/Al-layered double hydroxide nanohybrid synthesised using direct co-precipitation and ion exchange methods显示文摘 | Farahnaz Barahuie Mohd Zobir Hussein Palanisamy Arulselvan Sharida Fakurazi Zulkarnain Zainal | 2014 | Journal of Solid State Chemistry2014，，： | 1 |
| 16 | Determing of Factors Influencing the Success and Failure of HospitaI Information System and Their Evaluation Methods:A Systematic Review显示文摘 | Farahnaz S Khalil K Maryam A | 2013 | lran Red Cres Med2013，15，2： | 1 |
| 17 | Drug delivery system for an anticaneer agent, chlorogenate-Zn/A l-layered double hydroxide nanohybrid synthesised using direct co-precipitation and ion exchange methods显示文摘 | Farahnaz Barahuiea Mohd Zobir Hussein Palanisamy Arulselvanb el al | 2014 | Journal of Solid State Chemistry2014，217，： | 1 |
| 18 | Ranked k -medoids: A fast and accurate rank-based partitioning algorithm for clustering large datasets显示文摘 | Seyed Mohammad Razavi Zadegan Mehdi Mirzaie Farahnaz Sadoughi | 2013 | Knowledge-Based Systems2013，，： | 1 |
| 19 | Clinical Validation of an Office-Based 14C-UBT (Heliprobe) for H. pylori Diagnosis in Iranian Dyspeptic Patients显示文摘 | Fariborz Mansour-Ghanaei Omid Sanaei Farahnaz Joukar Y. Yamaoka | 2011 | Gastroenterology Research and Practice2011，，： | 1 |
| 20 | Preparation of FMD type A87/IRN inactivated vaccine by gamma irradiation and the im- mune response on guinea pig显示文摘 | Farahnaz M S Akbar K Kamal S | 2008 | Indian Journal Microbiology2008，48，： | 1 |
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