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| 1 | Experimental study of“Tong Xia”purgative method in ameliorating lung injury in acute necrotizing pancreatitis显示文摘AIM To investigate the role of tumor necrosisfactor(TNF)in lung injury during acutenecrotizing pancreatitis(ANP),and thetherapeutic effect of'Tong Xia'purgativemethod in minimizing the severity of lung injury.METHODS Fourteen canines were randomlydivided into 3 groups:the'Tong Xia'treatmentgroup(n = 5)using Dachengqitang;salinecontrol group(n = 5),and the sham operationgroup(n = 4).TNF activity in serum and inbronchoalveolar lavage fluid(BALF),the serumendotoxin levels were measured,and theseverity of lung injury evaluated.RESULTS Elevation of TNF activity was moreprominent in BALF than in serum.TNF activity inserum at 6 and 12 hours and in BALI:wassignificantly decreased in the'Tong Xia'treatment group than in the saline control one(q=21.11,q=12.07,q=9.03,respectively,P<0.01)and the lung injury was significantlyalleviated at 12 hours as compared with that inthe saline group,manifested as amelioration otthe lung wet/ dry weight ratio,decrease inprotein concentration and neutrophils count inBALF,and improvement of pulmonaryinflammatory changes.A positive correlationwas demonstrated between serum TNF activity and endotoxin level.CONCLUSION Hypersecretion of TNF is shownto be one of the major causes of lung injuryduring ANP;'Tong Xia'purgative method couldalleviate the degree of lung injury mediated byTNF. | Xia Q Jiang JM Gong X Chen GY Li L Huang ZW | 2000 | World Journal of Gastroenterology2000，6，1： | 31 |
| 2 | 全球沙尘气溶胶源汇分布及其变化特征的模拟分析显示文摘根据全球沙尘气溶胶气候模式GEM-AQ/EC模拟的1995~2004年的沙尘起沙量和干湿沉降量,分析了沙尘气溶胶源汇的全球时空变化特征.全球沙尘起沙量集中在各个主要沙漠地区,北非对全球沙尘气溶胶贡献最大为66.6%.沙尘气溶胶沉降的高值区分布在沙漠源区及其紧临的下风地区.最大净沙尘气溶胶接收主要分布在沙漠周围地区并形成净接收量大于10t/(km2·a)的位于0°N^60°N之间的北非、欧亚大陆、西太平洋、北印度洋、北美和大西洋的带状分布.在北非、阿拉伯半岛、中亚、东亚和澳大利亚5个主要沙漠地区中,起沙量和沉降量都存在明显的季节变化,除中亚其他4个区域干湿沉降量和起沙的季节变化基本一致;东亚地区沙尘气溶胶起沙量和总沉降量的季节变化最为明显,而北非沙漠起沙量和总沉降量的季节变化最小,其他3个区域的季节变化幅度基本相同.中亚起沙峰值和阿拉伯半岛起沙次峰值出现在夏季,其他区域的峰值均出现在春季.10年间全球陆地年平均起沙量为(1500±94)Mt,保持略微上升趋势.以北非沙漠起沙量年际变化率最低(6.3%),而以东亚(28.3%)和澳大利亚(45.0%)起沙量年际变化最为明显;全球陆地的沙尘气溶胶沉降量以约9.9Mt/a的速率递减,全球海洋的沙尘气溶胶沉降递增. | 刘建慧 赵天良 韩永翔 Gong S L 熊洁 | 2013 | 中国环境科学2013，33，10： | 19 |
| 3 | Establishment of hepatocellular carcinoma multidrug resistant monoclone cell line HepG2/mdr1显示文摘multidrug 抵抗(MDR ) 与 mdr1 基因和它的产品 P-glycoprotein 的表示联系了的背景是在癌房间(HCC ) 病人与化疗对待的 hepatocellular 的预后的一个主要因素。我们的学习是建立明确地,与转基因的 mdr1.Methods 的 overexpression 有关, 4.5-kb mdr1 cDNA 从 plasmid pHaMDR1-1 获得了的 multidrug 抵抗的 de novo 获得被克隆进 PCI-neo 哺乳动物的表示向量的一根稳定的 HCC MDR 房间线,后来被 liposome 转移到人的 hepatocarcinoma 房间线 HepG2 。然后,抵抗 G418 的 transfected HepG2 房间被聚类并且有教养并且在这些 HepG2 房间的 mdr1 cDNA, mRNA 和 P-glycoprotein (Pgp ) 的特定的碎片被 PCR, RT-PCR 和流动 cytometry 分别地检测。daunorubicin 的累积同时是由流动 cytometry 的 determinated。grafting 瘤的裸体老鼠模特儿被皮下地在正确腋下注射 HepG2/mdr1 房间建立。当瘤直径到达了 5 公里时, adriamycin 被注入腹洞。瘤的尺寸和生长抑制是 evaluated.Results mdr1 表示向量成功地被构造, MDR HCC 线 HepG2/mdr1 developed.The PCR 分析证明 mdr1 的特定的碎片在 HepG2/mdr1 的 cDNA 房间,然而并非在控制组 HepG2 房间。而且,在 HepG2/mdr1 房间的 mdr1 mRNA 和 Pgp 表示的特定的碎片的内容是(59. | CHEN Yong-bing YAN Mao-lin GONG Jian-ping XIA Ren-pin LIU Li-xin LI Ning LU Shi-chun ZHANG Jing-guang ZENG Dao-bing XIE Jian-guo YANG Jia-yin YAN Lü-nan | 2007 | Chinese Medical Journal2007，，8： | 16 |
| 4 | 1995~2004年东亚沙尘气溶胶的模拟源汇分布及垂直结构显示文摘利用全球气溶胶模式GEM-AQ/EC的1995-2004年10年沙尘气溶胶模拟,探讨了东亚地区沙尘气溶胶源汇分布和垂直结构特征.结果表明,东亚大陆沙尘气溶胶源区主要集中在东亚的沙漠地区,有两大沙尘主要源区:覆盖蒙古国南部及中国内蒙中西部的沙漠地区和南疆的塔克拉玛干沙漠.东亚沙尘排放量春季最大,占全年排放总量的66.81%,四月份达15.29Mt,夏季下降,秋季小幅度回升,冬季最小;东亚沙尘排放量呈现明显的年际变化及增强的趋势.东亚沙尘沉降高值区与源区一致,源区及附近以干沉降为主,远距离传输到中国东北、长江以南及西太平洋包括日本、朝鲜半岛,湿沉降占主导地位;沙尘沉降具有季节变化,其趋势与东亚沙尘排放量的季节变化大致相同,且模拟的10年沉降量呈上升趋势.东亚沙漠地区排放的沙尘主导了东亚沙尘气溶胶的变化,最大的净沙尘汇区集中在紧邻净沙尘源区的黄土高原及华北平原西部.东亚地区春夏秋3个季节均是沙尘的净源区,而冬季强西风急流输入东亚以外的沙尘使东亚整体上为沙尘净接收区.东亚大陆大部分地区,沙尘垂直分布主要集中在对流层低层3km高度以下,在西太平洋地区包括日本、朝鲜半岛沙尘高值中心位于在对流层中层5km高度上下,在沙漠以北地区沙尘垂直廓线的高值出现在对流层中上层6-8km高度. | 熊洁 赵天良 韩永翔 Gong S L | 2013 | 中国环境科学2013，33，6： | 15 |
| 5 | A study of hydrate plug formation in a subsea natural gas pipeline using a novel high-pressure flow loop显示文摘The natural gas pipeline from Platform QK18-1 in the southwest of Bohai Bay to the onshore processing facility is a subsea wet gas pipeline exposed to high pressure and low temperature for a long distance. Blockages in the pipeline occur occasionally. To maintain the natural gas flow in the pipeline, we proposed a method for analyzing blockages and ascribed them to the hydrate formation and agglomeration. A new high-pressure flow loop was developed to investigate hydrate plug formation and hydrate particle size, using a mixture of diesel oil, water, and natural gas as experimental fluids. The influences of pressure and initial flow rate were also studied. Experimental results indicated that when the flow rate was below 850 kg/h, gas hydrates would form and then plug the pipeline, even at a low water content (10%) of a water/oil emulsion. Furthermore, some practical suggestions were made for daily management of the subsea pipeline. | Li Wenqing Gong Jing Lü Xiaofang Zhao Jiankui Feng Yaorong Yu Da | 2013 | Petroleum Science2013，10，1： | 11 |
| 6 | Research on optimal immunization strategies for hepatitis B in different endemic areas in China显示文摘INTRODUCTION At present hepatitis B vaccine immunization is an unique effective measure for controlling hepatitis B.It is important o determine optimal immunization | Li H Wang L Wang SS Gong J Zeng XJ Li RC Nong Y Huang YK Chen XR Huang ZN | 2000 | World Journal of Gastroenterology2000，6，3： | 9 |
| 7 | Corrosion performance of Al–Al2O3 cold sprayed coatings on mild carbon steel pipe under thermal insulation显示文摘This paper focused on the corrosion resistance of cold spray Al–Al_2O_3composite coatings used on carbon steel pipe surfaces under thermal insulation. Al–Al_2O_3coatings were produced on the carbon steel pipe surface by cold spray(CS) technology. Experimental apparatus was built to test the corrosion resistance of coatings beneath mineral wool insulation under isothermal, thermal cycling and wet/dry conditions. The results showed that when α-Al_2O_3 was added in spraying powder, the coating could obtain higher hardness and a denser microstructure. From corrosionunder-insulation(CUI) tests, Al–Al_2O_3CS coatings were proven to be efficient in protecting carbon steel pipe from CUI mainly owning to lamellar microstructures of coatings. There was no evidence to show that α-Al_2O_3 might bring any negative effect on corrosion resistance. Al–Al_2O_3CS coatings were sensitive to the chloride ion concentration. When these coatings were exposed to higher concentrations of NaC l, the coating's exhibited faster degradation. | Xiaomin Bai Jianqun Tang Jianming Gong Xiaoliang Lü | 2017 | Chinese Journal of Chemical Engineering2017，25，4： | 7 |
| 8 | Purified human bone marrow multipotent mesenchymal stem cells regenerate infarcted myocardium in experimental rats显示文摘 | Zhang S Jia Z Ge J Gong L Ma Y Li T Guo J Chen P Hu Q Zhang P Liu Y Li Z Ma K Li L Zhou C | 2006 | 中国生物学文摘2006，20，5： | 5 |
| 9 | HBV编码的P蛋白通过FOXO3/miRNA-30b-5p/MINPP1轴启动糖酵解旁路促进HBV相关肝细胞癌的发展显示文摘[据Journal of Experimental&Clinical Cancer Research 2021年1月报道]题:HBV编码的P蛋白通过FOXO3/miRNA-30b-5p/MINPP1轴启动糖酵解旁路促进HBV相关肝细胞癌的发展(作者Chen W等)HBV慢性感染是引起肝癌的最主要病因,但其发病机制尚未完全阐明。 | 陈文标 刁宏燕 CHEN W JIANG J GONG L | 2021 | 临床肝胆病杂志2021，37，7： | 5 |
| 10 | JWA regulates melanoma metastasis by integrin alpha(V)beta(3) signaling(摘要)显示文摘 | Bai, J Zhang, J Wu, J Shen, L Zeng, J Ding, J Wu, Y Gong, Z Li, A Xu, S Zhou, J Li, G | 2010 | 南京医科大学学报(自然科学版)2010，30，8： | 4 |
| 11 | Grassland Degradation and Its Control in Region AroundQinghai Lake显示文摘A quite severe degradation was found in all seven types of grasslands in the study area involving 12counties of the northwestern Qinghai Province. The slightly, moderately and severely degraded grasslandsoccupied 49.7%, 32.0% and 18.3% of the area respectively. The major factors resulting in the degradationwere overgrazing, the damages from mice and grasshopper and blown sands, and improper use of grasslands.The measures to deal with these problems should be: 1) to make livestock development in accordancewith grassland carrying capacity for animals; 2) to build more artificial grasslands with a stable and highergraas yield; 3) to put more widely the rotation grazing system into practice; 4) to clear up the poisonousgrass species; and 5) to adopt more effective measures to deal with the damages to grasslands by mice andgrasshoppers. | JIANG JIANJUN NI SHAOXIANG GONG AIQI WANG WEIJUN ZHA YONG WANG JIECHENG F. VOSS(l College of Geographic Science, Nanjing Normal University, Nanjing 210097 (China))(2 General Grassland Station of Qinghai Province, Xining 810001 (China))(3 Institute of Ceog | 1999 | Pedosphere1999，9，4： | 4 |
| 12 | Tissue level microstructure and mechanical properties of the femoral head in the proximal femur of fracture patients显示文摘This study aims to investigate the regional variations of trabecular morphological parameters and mechanical parameters of the femoral head,as well as to determine the relationship between trabecular morphological and mechanical parameters.Seven femoral heads from patients with fractured proximal femur were scanned using a micro-CT system.Each femoral head was divided into 12 sub-regions according to the trabecular orientation.One 125 mm^3 trabecular cubic model was reconstructed from each sub-region.A total of 81 trabecular models were reconstructed,except three destroyed sub-regions from two femoral heads during the surgery.Trabecular morphological parameters,i.e.trabecular separation(Tb.Sp),trabecular thickness(Tb.Th),specific bone surface(BS/B V),bone volume fraction(BV/TV),structural model index(SMI),and degree of anisotropy(DA) were measured.Micro-finite element analyses were performed for each cube to obtain the apparent Young's modulus and tissue level von Mises stress distribution under 1%compressive strain along three orthogonal directions,respectively.Results revealed significant regional variations in the morphological parameters(P<0.05).Young's moduli along the trabecular orientation were significantly higher than those along the other two directions.In general,trabecular mechanical properties in the medial region were lower than those in the lateral region.Trabecular mechanical parameters along the trabecular orientation were significantly correlated with BS/BV,BV/TV,Tb.Th,and DA.In this study,regional variations of microstructural features and mechanical properties in the femoral head of patients with proximal femur fracture were thoroughly investigated at the tissue level.The results of this study will help to elucidate the mechanism of femoral head fracture for reducing fracture risk and developing treatment strategies for the elderly. | Linwei Lü Guangwei Meng He Gong Dong Zhu Jiazi Gao Yubo Fan | 2015 | Acta Mechanica Sinica2015，31，2： | 4 |
| 13 | Flexible Triboelectric Nanogenerator from Micro-nano Structured Polydimethylsiloxane显示文摘 | XIAO Xinze Lü Chao WANG Gong XU Ying WANG Jiping YANG Hai | 2015 | Chemical Research in Chinese Universities2015，31，3： | 3 |
| 14 | Simulation of the Accumulation Process of Biogenic Gas Hydrates in the Shenhu Area of Northern South China Sea显示文摘Objective Previous work has largely discussed the relations between sediment structures and accumulation of gas hydrates in the Shenhu area of South China Sea,but has not documented why the gas hydrates occurred at the seafloor topographic highs.Many gas hydrate exploration examples abroad also indicate that the saturation of | LIAO Jing GONG Jianming Lü Wanjun WU Nengyou YUE Baojing LUAN Xiwu HU Gaowei | 2016 | Acta Geologica Sinica(English Edition)2016，90，6： | 3 |
| 15 | Passively confined tests of axial dynamical compressive strength of concrete 显示文摘 | Gong J C Malvern L E | 1990 | Experimental Mechanics1990，，3： | 3 |
| 16 | Comparative mitochondrial genome analysis of Varunidae and its phylogenetic implications显示文摘Complete mitochondrial genomes(mitogenomes)can indicate phylogenetic relationships,as well as useful information for gene rearrangement mechanisms and molecular evolution.Currently,the phylogenetic location of the genus Varuna(Brachyura:Varunidae)has not been well resolved mainly because of limited representatives(only two extant species).Here,we determined a new mitogenome of this genus(Varuna litterata)and added the published mitogenomes to reconstruct the phylogeny of Varunidae.The 16368-bp mitogenome contains the entire set of 37 genes and a putative control region.The characteristics of this newly sequenced mitogenome were described and compared with the other 15 Varunidae mitogenomes.All 16 analyzed mitogenomes have identical gene order and similar molecular features.The sliding window and genetic distance analyses demonstrate highly variable nucleotide diversity,with comparatively low variability of COI and COII,and high variability of ND6.The nonsynonymous/synonymous substitution rates(dN/dS ratio)analysis shows that all 13 PCGs are under purifying selection and ATP8 gene evolves under the least selective pressure.Twelve tRNA genes,two rRNAs,one PCG,and the putative control region are found to be rearranged with respect to the pancrustacean ground pattern gene order.Tandem duplication/random loss model is adopted to explain the large-scale gene rearrangement events occurring in Varunidae mitogenomes.Phylogenetic analyses show that all Varunidae species are placed into one group,and form a sister clade with Macrophthalmidae.Nevertheless,the phylogenetic relationships within Varunidae are not completely consistent based on the two different datasets used in this study.These findings will contribute to a better understanding of gene rearrangement and molecular evolution in Varunidae mitogenomes,as well as provide insights into the phylogenetic studies of Brachyura. | Ying Zhang Li Gong Xinting Lu Zengliang Miao Lihua Jiang Bingjian Liu Liqin Liu Pengfei Li Xu Zhang Zhenming Lü | 2022 | Acta Oceanologica Sinica2022，41，6： | 2 |
| 17 | Effect of La on Partial Oxidation of Ethanol to Hydrogen over Ni/Fe Catalysts显示文摘The partial oxidation of ethanol to hydrogen was investigated over Ni/Fe/La catalysts prepared by the co precipitation method. The effects of introduction of La promoter and the reaction temperature on the catalytic performance were studied. It was found that the introduction of La into Ni/Fe catalysts is helpful to increase the selectivity to hydrogen and the stability of the catalysts. The results of XRD and XPS characterization show that the structure of the catalyst was changed during the reaction. The existence of LaFeO 3 species is possibly the main reason of the increase of the catalyst stability. | WANG Wei ping, WANG Zhi fei, DING Yan and LU¨ Gong xuan ** State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, P. R. China | 2003 | Chemical Research in Chinese Universities2003，19，2： | 2 |
| 18 | Base level change and depositional filling response of Jurassic in the Qiangtang Basin of Tibet显示文摘The base level during the deposition of Jurassic in the Qiangtang Basin shows a complete cycle from rising to falling. The base level change is closely connected with tectonic evolution of the basin,especially connected with Bangonghu-Nujiang ocean evolution process in the formation and evolution of the basin. It is also affected by climate. The Jurassic strata correspond to a long-term base level cycle sequence. The sequence is in fact a non-complete symmetrical cycle,consisting of rising hemicycle and falling hemicycle. It can be divided into 6 intermediate-term base level cycle sequences,including 2 carbonate sequences,3 mixture sedimentary sequences of carbonate and clastic rocks and one clastic sedimentary sequence. Depositional filling characteristics during base level change show that Bangonghu-Nujiang ocean spreads in Toarcian-Bajocian ages,and is at the height of spreading of Bangonghu-Nujiang ocean in Bathonian-Oxfordian ages. In that process,sea area became smaller because of the dry climate. Eventually,marine depositional filling is ended with the subduction and collision of Bangonghu-Nujiang ocean. | ZHANG ShangFeng1,2,ZHANG ChangMin1,HU MingYi1,GONG WenPing1,XIAO ChuanTao1,LIU AiHua1 & Lü Dong11 Remaining Resources Research Group of Geoscience College,Yangtze University,Jingzhou 434023,China 2 Key Laboratory of Exploration Technologies for Oil and Gas Resources,Ministry of Education of China,Yangtze University,Jingzhou 434023,China | 2009 | Science China Earth Sciences2009，52，S1： | 2 |
| 19 | Stromal cell derived factor-1 acutely promotes neural progenitor cell proliferation in vitro by a mechanism involving the ERK1/2 and PI-3K signal pathways显示文摘 | Gong X He X Qi L | 2006 | Cell Biol Int2006，30，5： | 1 |
| 20 | Effects of fish oil on lymphocyte proliferation cytokine production and intracellular signaling in weanling pigs显示文摘 | Liu Y Gong L Li D | 2003 | Arch Tieremah2003，57，： | 1 |
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