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| 1 | Management of oligometastatic non-small cell lung cancer patients:Current controversies and future directions显示文摘Oligometastatic non-small cell lung cancer(NSCLC)describes an intermediate stage of NSCLC between localized and widely-disseminated disease.This stage of NSCLC is characterized by a limited number of metastases and a more indolent tumor biology.Currently,the management of oligometastatic NSCLC involves radical treatment(radiotherapy or surgery)that targets the metastatic lesions and the primary tumor to achieve disease control.This approach offers the potential to achieve prolonged survival in patients who,in the past,would have only received palliative measures.The optimal therapeutic strategies for the different scenarios of oligometastatic disease(intracranial vs extracranial disease,synchronous vs metachronous)remain undefined.Given the lack of head-to-head studies comparing radiotherapy to surgery in these patients,the decision to apply surgery or radiotherapy(with or without systemic treatment)must be based on prognostic factors that allow us to classify patients.This classification will allow us to select the most appropriate therapeutic strategy on an individualized basis.In the future,the molecular or microRNA profiles will likely improve the treatment selection process.The objective of the present article is to review the most relevant scientific evidence on the management of patients with oligometastatic NSCLC,focusing on the role of radiotherapy and surgery.We also discuss areas of controversy and future directions. | Felipe Counago Javier Luna Luis Leonardo Guerrero Blanca Vaquero María Cecilia Guillén-Sacoto Teresa González-Merino Begona Taboada Verónica Díaz Belén Rubio-Viqueira Ana Aurora Díaz-Gavela Francisco JoséMarcos Elia del Cerro | 2019 | World Journal of Clinical Oncology2019，10，10： | 5 |
| 2 | Treatment of the collapsed femoral head by containment in Legg-Calve-Perthes disease显示文摘 | Grzegorzewski A Bowen JR Guille JT | 2003 | J Pediatr Orthop2003，23，1： | 1 |
| 3 | Effect of ethylene concentration on quality parameters of fresh tomatoes stored using a carbon-heat hybrid ethylene scrubber显示文摘 | Domingo Martínez-Romero Fabián Guillén Salvador Castillo Pedro Javier Zapata Daniel Valero María Serrano | 2008 | Postharvest Biology and Technology2008，，2： | 1 |
| 4 | Antioxidant and antimicrobial peptide fractions from squid and tuna skin gelatin显示文摘 | GUILL N G L PEZ CABALLERO M ALEM N A | 2010 | 2010，，： | 1 |
| 5 | Early endoscopic realignment of post-traumatic posterior urethral disruption显示文摘 | S.M Moudouni J.J Patard A Manunta P Guiraud B Lobel F Guillé | 2001 | Urology2001，，4： | 1 |
| 6 | The treatment of bladder endometriosis显示文摘 | Sánchez Merino JM Guillán Maquieira C García Alonso J | 2005 | Arch Esp Urol2005，58，： | 1 |
| 7 | SnO2:F thin films deposited by RF magnetron sputtering: effect of the SnF2 amoun! in the target on the physical properties显示文摘 | Moure-Floresa F de Guill' en-Cervantesb A Nieto-Zepedab K E et aI | 2013 | Revista Mexicana de Fisica2013，59，： | 1 |
| 8 | Evaluation and management of the pediatric thyroid nodule 显示文摘 | Guille JT Opoku - Boateng A Thiheault SL | 2015 | Oneologist2015，，： | 1 |
| 9 | Claudin-low breast cancers:clinical,pathological,molecular and prognostic characterization显示文摘 | Sabatier R Finetti P Guille A | 2014 | Mol Cancer2014，13，： | 1 |
| 10 | Brief reports: A distinct DNA methylation signature defines breast cancer stem cells and pre- dicts cancer outcome显示文摘 | E1 Helou R Wieinski J Guille A | 2014 | Stem Cells2014，32，11： | 1 |
| 11 | Evalution and treatment of diastematomyelia显示文摘 | Miller A Guille JT Bowen JR | 1993 | J Bone Joint Surg(Am)1993，75，9： | 1 |
| 12 | Event detection, tracking, and visual- ization in Twitter: a mention-anomaly-based approach 显示文摘 | GUILLE A FAVRE C | 2015 | Social Network Analysis and Mining2015，5，1： | 1 |
| 13 | Study of thepolyphenol content of red and white grape varieties by liquid chromatogra-phy-mass spectrometry and its relationship to antioxidant power显示文摘 | ALONSO BORBALNM ZORRO L GUILLN D A | 2003 | Jour-nal of Chromatography A2003，1012，： | 1 |
| 14 | Ethanol consumption impairs regulation of fatty acid metabolism by decreasing the activity of AMP-activated protein kinase in rat liver显示文摘 | García-Villafranca J Guillén A Castro J | 2008 | Biochimie2008，90，： | 1 |
| 15 | Automated solid-phaseextraction for sample preparation followed by high-performance liquid chro-matography with diode array and mass spectrometric detection for the anal-ysis of resveratrol derivatives in wine显示文摘 | DOMNGUEZ C GUILLN D A BARROSO C G | 2001 | Journal of Chromatography A2001，918，： | 1 |
| 16 | The treatment of bladder endometriosis显示文摘 | Sánchez Merino JM Guillán Maquieira C García Alonso J | | 0，，03： | 1 |
| 17 | Evaluation and treatment of diastematomyelia显示文摘 | Guille JT Bowen JR | 1993 | J Bone Joint Surg Am1993，75，： | 1 |
| 18 | Changes in cell-wall-degrading enzyme activities in stored olives in relation to respiration and ethylene production Influence of exogenous ethylene显示文摘 | Juan Fernández-Bola?os A. Heredia Blanca Vioque José María Castellano Rafael Guillén | 1997 | Zeitschrift für Lebensmitteluntersuchung und - forschung A1997，，4： | 1 |
| 19 | Complications related to ovarian stimulation and oocyte retrieval in 4052 oocyte donor cycles显示文摘 | Bodri D Guillén JJ Polo A | | 0，，： | 1 |
| 20 | Low-density parity-check codes for nonergodic block-fading channels 显示文摘 | Boutros J J Guill~n i Fabregas A Bigliefi E | 2010 | IEEE Transactions on Information Theory2010，56，9： | 1 |
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