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| 1 | 畸胎瘤细胞源性生长因子和血管内皮生长因子在食管鳞癌中的表达及临床意义显示文摘目的探讨食管鳞癌(ESCC)中畸胎瘤细胞源性生长因子(PCDGF)、血管内皮生长因子(VEGF)的表达与肿瘤临床病理参数之间的关系,明确PCDGF和VEGF在血管生成中的作用。方法以免疫组化方法检测郑州大学第一附属医院2005年7月至2006年5月收治的50例食管鳞癌患者手术切除标本PCDGF与VEGF的表达,并以CD105抗体标记肿瘤组织血管内皮细胞,计算肿瘤间质微血管密度(MVD)。结果食管鳞癌中PCDGF、VEGF的表达较正常食管上皮明显增加(P<0.01);PCDGF和VEGF与肿瘤的浸润深度、TNM分期和淋巴结转移呈正相关(P均<0.05);PCDGF、VEGF的表达与MVD值呈显著正相关(P<0.01);PCDGF的表达与VEGF的表达呈正相关(P<0.05)。结论PCDGF标记癌组织的敏感性较高,有望成为一种新的食管鳞癌肿瘤标志物。食管鳞癌中PCDGF、VEGF的表达与血管生成关系密切,可能通过促进肿瘤新生血管生成参与肿瘤的生长、浸润和转移。 | 梁倩萍 李建生 Ginette Serrero 贺德志 苏惠 | 2008 | 中国实用内科杂志2008，28，1： | 6 |
| 2 | Association between early viral lower respiratory tract infections and subsequent asthma development显示文摘BACKGROUND The association between hospitalization for human respiratory syncytial virus(HRSV)bronchiolitis in early childhood and subsequent asthma is well established.The long-term prognosis for non-bronchiolitis lower respiratory tract infections(LRTI)caused by viruses different from HRSV and rhinovirus,on the other hand,has received less interest.AIM To investigate the relationship between infant LRTI and later asthma and examine the influence of confounding factors.METHODS The PubMed and Global Index Medicus bibliographic databases were used to search for articles published up to October 2021 for this systematic review.We included cohort studies comparing the incidence of asthma between patients with and without LRTI at≤2 years regardless of the virus responsible.The meta-analysis was performed using the random effects model.Sources of heterogeneity were assessed by stratified analyses.RESULTS This review included 15 articles(18 unique studies)that met the inclusion criteria.LRTIs at≤2 years were associated with an increased risk of subsequent asthma up to 20 years[odds ratio(OR)=5.0,95%CI:3.3-7.5],with doctor-diagnosed asthma(OR=5.3,95%CI:3.3-8.6),current asthma(OR=5.4,95%CI:2.7-10.6),and current medication for asthma(OR=1.2,95%CI:0.7-3.9).Our overall estimates were not affected by publication bias(P=0.671),but there was significant heterogeneity[I 2=58.8%(30.6-75.5)].Compared to studies with hospitalized controls without LRTI,those with ambulatory controls had a significantly higher strength of association between LRTIs and subsequent asthma.The strength of the association between LRTIs and later asthma varied significantly by country and age at the time of the interview.The sensitivity analyses including only studies with similar proportions of confounding factors(gender,age at LRTI development,age at interview,gestational age,birth weight,weight,height,smoking exposure,crowding,family history of atopy,and family history of asthma)between cases and controls did not alter the overall estimates.CONCLUSION Regardless of the causative virus and confounding factors,viral LRTIs in children<2 years are associated with an increased risk of developing a subsequent asthma.Parents and pediatricians should be informed of this risk. | Sebastien Kenmoe Etienne Atenguena Okobalemba Guy Roussel Takuissu Jean Thierry Ebogo-Belobo Martin Gael Oyono Jeannette Nina Magoudjou-Pekam Ginette Irma Kame-Ngasse Jean Bosco Taya-Fokou Chris Andre Mbongue Mikangue Raoul Kenfack-Momo Donatien Serge Mbaga Arnol Bowo-Ngandji Cyprien Kengne-Ndé Seraphine Nkie Esemu Richard Njouom Lucy Ndip | 2022 | World Journal of Critical Care Medicine2022，11，4： | 3 |
| 3 | FGF-2 and FGF-1 expressed in rat bladder carcinoma cells have similar angiogenic potential but different tumorigenic properties in vivo显示文摘 | JACQEUELINE J JEAN P GINETTE M | 1997 | Ocogene1997，14，6： | 1 |
| 4 | Recurrent and novel LDL receptor gene mutations causing heterozygous familial hypercholesterolemia in La Habana显示文摘 | Erasmo Pereira Raoul Ferreira Brigitte Hermelin Ginette Thomas Chantal Bernard Véronique Bertrand Hadad Nassiff Dora Mendez Castillo Gilbert Bereziat Pascale Benlian | 1995 | Human Genetics1995，，3： | 1 |
| 5 | Social Support, Depression, and Mortality During the First Year After Myocardial Infarction显示文摘 | Nancy Frasure-Smith Fran?ois Lespérance Ginette Gravel Aline Masson Martin Juneau Mario Talajic Martial G. Bourassa | 2000 | Circulation: Journal of the American Heart Association2000，，16： | 1 |
| 6 | Two Brassica napus polygalacturonase inhibitory protein genes are expressed at different levels in response to biotic and abiotic stresses显示文摘 | Rugang Li Roger Rimmer Min Yu Andrew G. Sharpe Ginette Séguin-Swartz Derek Lydiate Dwayne D. Hegedus | 2003 | Planta2003，，2： | 1 |
| 7 | Determination of Free and Liposome-Associated Doxorubicin and Vincristine Levels in Plasma under Equilibrium Conditions Employing Ultrafiltration Techniques显示文摘 | Lawrence D. Mayer Ginette St.-Onge | 1995 | Analytical Biochemistry1995，，2： | 1 |
| 8 | FGF-2 and FGF-1 expressed in rat bladder carcinoma cells have similar angiogenic potential but different tumorigenic properties in vivo 显示文摘 | Jean P Ginette M | 1997 | Ocogene1997，14，： | 1 |
| 9 | In vivo transfer interleukin-1 receptor antagonist gene in osteoarthritic rabbit knee joints显示文摘 | Julio F Ginette T Johanne MP | | 0，，： | 1 |
| 10 | Role of interleukin‐1 and tumor necrosis factor α in matrix degradation of human osteoarthritic cartilage显示文摘 | MasahikoKobayashi Ginette R.Squires AishaMousa MichaelTanzer David J.Zukor JohnAntoniou UlrichFeige A. RobinPoole | 2005 | Arthritis & Rheumatism2005，，1： | 1 |
| 11 | Inhibition of PC cell-derived growth factor (PCDGF, epithelinygranulin precursor) expression by antisense PCDGF cDNA transfection inhibits tumorigenicity of the human breast carcinoma cell line MDA-MB-468 显示文摘 | Runqing Lu Ginette S | 2000 | PNAS2000，97，8： | 1 |
| 12 | Communication Skills in Standardized-Patient Assessment of Final-Year Medical Students: A Psychometric Study显示文摘 | Gretchen Guiton Carol S. Hodgson Ginett Delandshere Luann Wilkerson | 2004 | Advances in Health Sciences Education2004，，3： | 1 |
| 13 | Influence of service cracking on reinforcement steel corrosion显示文摘 | RAOUL F GINETTE A | 1998 | Journal of Materials in Civil Engineering1998，，： | 1 |
| 14 | Occurrence and spatial and temporal variations of disinfection by-products in the water and air of two indoor swimming pools 显示文摘 | CATTO C SABRINA S GINETTE CT | 2012 | Inter J Env Res Pub Heal2012，9，8： | 1 |
| 15 | Mediation of estrogen mitogenic effect in human breast cancer MCF-7 cells by PC-cell-derived growth factor (PCDGF/granulin precursor)显示文摘 | Runqing Lu Ginette Serrero | 2001 | Proc Natl Acad Sci2001，98，： | 1 |
| 16 | Inhibition of PC cell-derived growth factor (PCDGF, epithelin/granulin precursor) expression by antisense PCDGF cDNA transfection inhibits tumorigenicity of the human breast carcinoma cell line MDA-MB-468显示文摘 | Runqing Lu Ginette Serrero | | Proc Natl Acad Sc0，，： | 1 |
| 17 | Induction of Transglutaminase 2 by a Liver X Receptor/Retinoic Acid Receptor α Pathway Increases the Clearance of Apoptotic Cells by Human Macrophages显示文摘 | Cédric Rébé Magalie Raveneau Angélique Chevriaux Daniela Lakomy Anne-Laure Sberna Annie Costa Ginette Bessède Anne Athias Eric Steinmetz Jean Marc A. Lobaccaro Georges Alves Alexandre Menicacci Sébastien Vachenc Eric Solary Philippe Gambert David Masson | 2009 | Circulation Research2009，，4： | 1 |
| 18 | Communication Skills in Standardized-Patient Assessment of Final-Year Medical Students: A Psychometric Study显示文摘 | Gretchen Guiton Carol S. Hodgson Ginett Delandshere Luann Wilkerson | | 0，，： | 1 |
| 19 | Methods for in vivo dosimetry in external radiotherapy 显示文摘 | JAN V D GINETTE M | 1994 | Physics for clinical radiotherapy1994，160，： | 1 |
| 20 | Role of interleukin and tumor necrosis factorc in mat rix degradalion of human osteoarlhri- ic cartilage显示文摘 | Masahiko K Ginette RS Aisha M | 2005 | Art hritis & Rheum2005，52，1： | 1 |
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