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| 1 | Spatial analyzing system for urban land-use management based on GIS and multi-criteria assessment modeling显示文摘城市的陆地管理在城市的计划和开发上在生态的过程,环境进程和过程上要求大量数据的集成。这篇论文联合了与遥感(RS ) 当模特儿的陆地适用性,美化生态的分析和地理信息系统(GIS ) 为城市的扩大陆地管理开发一个空间分析系统。空间分析系统为城市的扩大土地的适用性评估在 GIS 合并多标准机制的使用。灰关系分析(GRA ) 与分析层次过程(AHP ) 被相结合在评估的过程期间探讨不确定性。这条途径被使用明确地在长沙城市里为未来陆地保存和开发识别限制和机会,中国。方法论的确认关于生态的适用性与以前的独立研究显示出巧合的高度。方法论能在环境保护,陆地管理并且地区性的计划是有用的。 | Fu Yang Guangming Zeng Chunyan Du Lin Tang Jianfei Zhou Zhongwu Li | 2008 | Progress in Natural Science:Materials International2008，18，10： | 12 |
| 2 | Programmed Death Ligand-1 on Microglia Regulates Th1 Differentiation via Nitric Oxide in Experimental Autoimmune Encephalomyelitis显示文摘Microglia are considered to be potential antigen-presenting cells and have the ability to present antigen under pathological conditions. Nevertheless, whether and how microglia are involved in immune regulation are largely unknown. Here, we investigated the suppressive activity of microglia during experimental autoimmune encephalomyelitis(EAE) induced by myelin oligodendrocyte glycoprotein, with the goal of understanding their role in regulating the T cell reaction. Using flow cytometric analysis, we found that microglia were characterized by increased cell number and up-regulated programmed death ligand-1(PD-L1) at the peak phase of EAE. Meanwhile,both the CD^(4+)T cells and microglia that infiltrated the central nervous system expressed higher levels of PD1, the receptor for PD-L1, accompanied by a decline of Th1 cells.In an ex vivo co-culture system, microglia from EAE mice inhibited the proliferation of antigen-specific CD^(4+)T cells and the differentiation of Th1 cells, and this was significantly inhibited by PD-L1 blockade. Further,microglia suppressed Th1 cells via nitric oxide(NO), the production of which was dependent on PD-L1. Thus, these data suggest a scenario in which microglia are involved in the regulation of EAE by suppressing Th1-cell differentiation via the PD-L1-NO pathway. | Jingxia Hu Hao He Zhengang Yang Guangming Zhu Li Kang Xiuli Jing Hai Lu Wengang Song Bo Bai Hua Tang | 2016 | Neuroscience Bulletin2016，32，1： | 9 |
| 3 | Research on Key Technologies of Network Security Situational Awareness for Attack Tracking Prediction显示文摘This paper analyzed the existing network security situation evaluation methods and discovered that they cannot accurately reflect the features of large-scale,synergetic, multi-stage gradually shown by network attack behaviors. For this purpose, the association between attack intention and network configuration information was deep analyzed. Then a network security situation evaluation method based on attack intention recognition was proposed. Unlike traditional method, the evaluation method was based on intruder. This method firstly made causal analysis of attack event and discovered and simplified intrusion path to recognize every attack phases, then realized situation evaluation based on the attack phases. Lastly attack intention was recognized and next attack phase was forecasted based on achieved attack phases, combined with vulnerability and network connectivity. A simulation experiments for the proposed network security situation evaluation model is performed by network examples. The experimental results show that this method is more accurate on reflecting the truth of attack. And the method does not need training on the historical sequence, so the method is more effective on situation forecasting. | KOU Guang WANG Shuo TANG Guangming | 2019 | Chinese Journal of Electronics2019，28，1： | 6 |
| 4 | Development of an automatic calibration device for high-accuracy low temperature thermometers显示文摘Based on the analysis and investigation of calibration systems for high-accuracy low temperature thermometers,a new facility for automatic calibration of high-accuracy low temperature thermometers was developed.Continuous calibration for multiple points can be made automatically with this device.According to the thermophysical characteristics of the constant-temperature block in this device,segmented Fuzzy-PID (proportional-integral-differential) algorithm was applied.The experimental results showed that the temperature fluctuation was smaller than ±0.005 K in 30 min.Therefore,this new device can fully meet the calibration requirement of high-precision low temperature thermometers. | CHEN GuangMing,GAO Xu,ZHANG ShaoZhi,CHEN Qi,TANG LiMing & LAN YuQi Institute of Refrigeration and Cryogenics,Zhejiang University,Hangzhou 310027,China | 2010 | Science China(Technological Sciences)2010，53，9： | 6 |
| 5 | Identification and isolation of Mu-flanking fragments from maize显示文摘Transposable elements have been utilized as mutagens to create mutant libraries for functional genomics. Isolation of genomic seg-ments flanking the insertion Mutator (Mu) is a key step in insertion mutagenesis studies. Herein, we adopted a modified AFLP method to identify and isolate Mu-flanking fragments from maize. The method consists of the following steps: 1) double-digestion of genomic DNA with Bgl II/Msp I and ligation of digested fragments to the Bgl II-and Msp I-adaptors; 2) enrichment of a subset of Bgl II/Msp I fragments followed by selective amplification of the Mu-flanking fragments; 3) simultaneous display of AFLP bands derived from the flanking re-gions for both insert and native Mu transposons; 4) identification and isolation of AFLP bands resulting from Mu insertions by comparing the banding profiles between Mu-induced mutants and their parental lines; and 5) confirmation of flanking fragments related to these Mu insertions. Using this approach, we have isolated flanking fragment(s) resulting from Mu insertion for every Mu-induced mutant, and one such fragment, M196-FF, is found to contain a partial sequence of the DNA topoisomerase I gene Top1. Moreover, the modified AFLP method including all restriction enzymes, adaptors and primers has been optimized in this study. The modified AFLP method has been proved to be simple and efficient in the isolation of Mu-flanking fragments and will find its usefulness in the functional genomics of maize. | Yijun Wang Guangming Yin Qin Yang Jihua Tang Xiaomin Lu Schuyler S. Korban Mmghang Xu | 2008 | Journal of Genetics and Genomics2008，35，4： | 4 |
| 6 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 7 | Three-dimensional silk fibroin scaffolds enhance the bone formation and angiogenic differentiation of human amniotic mesenchymal stem cells:a biocompatibility analysis显示文摘Silk fibroin(SF)is a fibrous protein with unique mechanical properties,adjustable biodegradation,and the potential to drive differentiation of mesenchymal stem cells(MSCs)along the osteogenic lineage,making SF a promising scaffold material for bone tissue engineering.In this study,hAMSCs were isolated by enzyme digestion and identified by multiple-lineage differentiation.SF scaffold was fabricated by freeze-drying,and the adhesion and proliferation abilities of hAMSCs on scaffolds were determined.Osteoblast differentiation and angiogenesis of hAMSCs on scaffolds were further evaluated,and histological staining of calvarial defects was performed to examine the cocultured scaffolds.We found that hAMSCs expressed the basic surface markers of MSCs.Collagen type I(COLI)expression was observed on scaffolds cocultured with hAMSCs.The scaffolds potentiated the proliferation of hAMSCs and increased the expression of COL-I in hAMSCs.The scaffolds also enhanced the alkaline phosphatase activity and bone mineralization,and upregulated the expressions of osteogeniorelated factors in vitro.The scaffolds also enhanced the an gioge nic differe ntiati on of hAMSCs.The cocultured scaffolds in creased bone formati on in treating critical calvarial defects in mice.This study first demonstrated that the application of 3D SF scaffolds co-cultured with hAMSCs greatly enhaneed osteogenic differentiation and angiogenesis of hAMSCs in vitro and in vivo.Thus,3D SF scaffolds cocultured with hAMSCs may be a better alter native for bone tissue engin eering. | Yuwan Li Ziming Liu Yaping Tang Qinghong Fan Wei Feng Changqi Luo Guangming Dai Zhen Ge Jun Zhang Gang Zou Yi Liu Ning Hu Wei Huang | 2020 | Acta Biochimica et Biophysica Sinica2020，52，6： | 2 |
| 8 | Ultrawideband chromatic aberration-free meta-mirrors显示文摘Chromatic aberration-free meta-devices(e.g.,achromatic meta-devices and abnormal chromatic meta-devices)play an essential role in modern science and technology.However,current efforts suffer the issues of low efficiency,narrow operating band,and limited wavefront manipulation capability.We propose a general strategy to design chromatic aberration-free meta-devices with high-efficiency and ultrabroadband properties,which is realized by satisfying the key criteria of desirable phase dispersion and high reflection amplitudes at the target frequency interval.The phase dispersion is tuned successfully based on a multiresonant Lorentz model,and high reflection is guaranteed by the presence of the metallic ground.As proof of the concept,two microwave meta-devices are designed,fabricated,and experimentally characterized.An achromatic meta-mirror is proposed within 8 to 12 GHz,and another abnormal chromatic meta-mirror can tune the reflection angle as a linear function.Both meta-mirrors exhibit very high efficiencies(85%to 94%in the frequency band).Our findings open a door to realize chromatic aberration-free meta-devices with high efficiency and wideband properties and stimulate the realizations of chromatic aberration-free metadevices with other functionalities or working at higher frequency. | Tong Cai Shiwei Tang Bin Zheng Guangming Wang Wenye Ji Chao Qian Zuojia Wang Erping Li Hongsheng Chena | 2021 | Advanced Photonics2021，3，1： | 2 |
| 9 | Biotinylated dextran amine anterograde tracing of the canine corticospinal tract显示文摘In this study, biotinylated dextran amine (BDA) was microinjected into the left cortical motor area of the canine brain. Fluorescence microscopy results showed that a large amount of BDA-labeled pyramidal cells were visible in the left cortical motor area after injection. In the left medulla oblongata, the BDA-labeled corticospinal tract was evenly distributed, with green fluorescence that had a clear boundary with the surrounding tissue. The BDA-positive corticospinal tract entered into the right lateral funiculus of the spinal cord and descended into the posterior part of the right lateral funiculus, close to the posterior horn, from cervical to sacral segments. There was a small amount of green fluorescence in the sacral segment. The distribution of BDA labeling in the canine central nervous system was consistent with the course of the corticospinal tract. Fluorescence labeling for BDA gradually diminished with time after injection. Our findings indicate that the BDA anterograde tracing technique can be used to visualize the localization and trajectory of the corticospinal tract in the canine central nervous system. | Xiao Han Guangming Lv Huiqun Wu Dafeng Ji Zhou Sun Yaofu Li Lemin Tang | 2012 | Neural Regeneration Research2012，7，11： | 2 |
| 10 | Conductive resilient graphene aerogel via magnesio- thermic reduction of graphene oxide assemblies显示文摘Graphene aerogels 为精力存储和变换是合乎需要的,作为催化作用支持,并且作为为环境补习的吸附物。当维持高电的电导率和强壮的技工性能时,与低密度生产 graphene aerogels,我们综合了由 freeze-dried graphene 氧化物的 magnesiothermic 减小的 graphene aerogels (去) 自己组装、随后在酸形成的 MgO 蚀刻答案。减少的 graphene 氧化物( rGO ) aerogel 样品展出了象 1.1 mg 一样低的密度????????????????????????????????????????吗???敤牧摡'L汩瑩????????????????????? | Huang Tang Peibo Gao Zhihao Bao Bin Zhou Jun Shen Yongfeng Mei Guangming Wu | 2015 | Nano Research2015，8，5： | 2 |
| 11 | Anovel three - axis force sensor for advanced training ofshot - put athletes 显示文摘 | Guangming Song Hongyan Yuan Yi Tang | 2006 | Sensors and Actuators2006，，： | 1 |
| 12 | A novel ejector-absorption eombined refrigeration cycle 显示文摘 | Hong Daliang Chen Guangming Tang Liming | 2011 | lnterantional Journal of Refrigeration2011，34，7： | 1 |
| 13 | DETERMINATION OF CHLORPYRIFOS AND ITS MAIN DEGRADATION PRODUCT TCP IN WATER SAMPLES BY DISPERSIVE LIQUID–LIQUID MICROEXTRACTION BASED ON SOLIDIFICATION OF FLOATING ORGANIC DROPLET COMBINED WITH HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY显示文摘 | Jianfei Xiong Guangming Zhou Zhuo Guan Xiangyu Tang Qiang He Limin Wu | 2014 | Journal of Liquid Chromatography & Related Technologies2014，，11： | 1 |
| 14 | Offshore and near shore chlorophyll increases induced by typhoon and typhoon rain显示文摘 | Guangming Zheng Danling Tang | 2007 | Marine Ecology Progress Series2007，333，3： | 1 |
| 15 | Effect of biodelignification of rice straw on humification and humus quality by Phanerochaete chrysosporium and Streptomyces badius显示文摘 | HongLi Huang GuangMing Zeng Lin Tang HongYan Yu XingMei Xi ZhaoMeng Chen GuoHe Huang | 2007 | International Biodeterioration & Biodegradation2007，，4： | 1 |
| 16 | Detection of phenylhydrazine based on lectin-glycoenzyme multilayer-film modified biosensor显示文摘 | TANG Lin ZENG Guangming YANG Yunhui | 2005 | Int J Environ Anal Chem2005，85，2： | 1 |
| 17 | Offshore and nearshore chlorophyll increases induced by typhoon winds and subsequent terrestrial rainwater runoff显示文摘 | ZHENG Guangming TANG Danling | 2007 | Marine Ecology Progress Series2007，333，： | 1 |
| 18 | A novel ejector-absorption combined refrigeration cycle 显示文摘 | Hong Daliang Chen Guangming Tang Liming | 2010 | International Journal of Refrigeration2010，34，7： | 1 |
| 19 | Combining AHP with GIS in synthetic evaluation of eco-environment quality-A case study of Hunan Province显示文摘 | Ying Xiong Zeng Guangming Chen Guiqiu Tang Lin Wang Kelin Huang Daoyou | 2007 | Ecological Modelling2007，209，24： | 1 |
| 20 | A novel ejector - absorption combined refrigeration cycle 显示文摘 | Daliang Hong Guangming Chen Liming Tang | 2011 | International Journal of Refrigeration2011，34，： | 1 |
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