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| 1 | Potential and challenges of tannins as an alternative to in-feed antibiotics for farm animal production显示文摘Naturally occurring plant compounds including tannins, saponins and essential oils are extensively assessed as natural alternatives to in-feed antibiotics.Tannins are a group of polyphenolic compounds that are widely present in plant region and possess various biological activities including antimicrobial,anti-parasitic, anti-viral, antioxidant, anti-inflammatory, immunomodulation, etc.Therefore, tannins are the major research subject in developing natural alternative to in-feed antibiotics.Strong protein affinity is the well-recognized property of plant tannins, which has successfully been applied to ruminant nutrition to decrease protein degradation in the rumen, and thereby improve protein utilization and animal production efficiency.Incorporations of tannin-containing forage in ruminant diets to control animal pasture bloat, intestinal parasite and pathogenic bacteria load are another 3 important applications of tannins in ruminant animals.Tannins have traditionally been regarded as 'anti-nutritional factor' for monogastric animals and poultry, but recent researches have revealed some of them, when applied in appropriate manner, improved intestinal microbial ecosystem, enhanced gut health and hence increased productive performance.The applicability of plant tannins as an alternative to in-feed antibiotics depends on many factors that contribute to the great variability in their observed efficacies. | Qianqian Huang Xiuli Liu Guoqi Zhao Tianming Hu Yuxi Wang | 2018 | Animal Nutrition2018，，2： | 54 |
| 2 | Differential Hydrocarbon Enrichment and its Main Controlling Factors in Depressions of the Bohai Bay Basin Differential Hydrocarbon Enrichment and its Main Controlling Factors in Depressions of the Bohai Bay Basin显示文摘Significant differential hydrocarbon enrichment occurs in depressions in a petroliferous basin.There are multiple depressions in the Bohai Bay Basin, and each depression as a relatively independent unit of hydrocarbon generation, migration and accumulation, contains significantly different hydrocarbon generation conditions and enrichment degree. On the basis of previous documents and a large number of statistical data, this work comparatively analyzed the differential hydrocarbon enrichment and its major controlling factors in depressions of the Bohai Bay Basin. The results show that depressions in the Bohai Bay Basin have various hydrocarbon enrichment degrees, and can be categorized into four types, namely enormously oil-rich, oil-rich, oily and oil-poor depressions. In general, the enormously oil-rich and oil-rich depressions are distributed in the eastern part of the basin along the Tan-Lu and Lan-Liao faults, whereas depressions in the western part of the basin are poor in hydrocarbons. Moreover, the vertical distribution of hydrocarbons is also highly heterogeneous, with Pre-Paleogene strata rich in hydrocarbons in the northern and western depressions, Paleogene strata rich in hydrocarbons in the entire basin, and Neogene strata rich in hydrocarbons in the off-shore areas of the Bohai Bay Basin. From early depressions in onshore areas to the late depressions in offshore areas of the Bohai Bay Basin, the source rocks and source-reservoir-cap rock assemblages gradually become younger and shallower, and the hydrocarbon resource abundance gradually increases. Hydrocarbon supplying condition is the key factor constraining the hydrocarbon enrichment for different depressions,while the main source-reservoir-cap rock assemblage, sufficient hydrocarbons and the transportation capacity of faults control the vertical distribution of hydrocarbons. The main factors controlling hydrocarbon enrichment are different for different layers. The hydrocarbon supplying condition of source rocks is the key controlling factor, whereas the source-reservoir configuration, the main sourcereservoir-cap rock assemblages, and the fault transportation are the main factors of hydrocarbon enrichment in the Paleogene, Paleogene and Neogene, respectively. | JIANG Youlu LIU Hua SONG Guoqi WANG Yongshi LIU Jingdong ZHAO Kai LYU Xueying | 2017 | Acta Geologica Sinica(English Edition)2017，91，5： | 15 |
| 3 | Effects of dietary alfalfa flavonoids extraction on growth performance,organ development and blood biochemical indexes of Yangzhou geese aged from 28 to 70 days显示文摘This experiment was conducted to study the effects of dietary alfalfa flavonoids extraction supplemental level on growth performance, organ development and blood biochemical indexes of Yangzhou geese at the age of 28 to 70 days. Two hundred and forty 21-day-old healthy male geese with similar body weight were randomly distributed into 4 groups with 6 replicates per group and 10 geese per replicate. Geese in the control group were fed a basal diet and the others in the experimental groups(groups 1,2, and 3) were fed experimental diets supplemented with 150, 300 and 450 mg/kg alfalfa flavonoids extraction(the concentration of it was 81%), respectively. The experiment had 7 days for pre-test and 42 days for formal test.The results showed that the final body weight and average daily intake of group 2 were significantly higher than those of other groups(P < 0.05). The average daily gain of group 2 was significantly higher than that in the control group and group 1(P < 0.05). There was no significant difference in feed-to-gain ratio between each group(P > 0.05). Pre-slaughter live weight, carcass weight, slaughter rate, semieviscerated weight, semi-eviscerated rate, eviscerated weight, eviscerated rate, leg muscle weight and leg muscle rate had no significant difference between each group(P > 0.05). The breast muscle weight and ratio of each test group were significantly higher than those in the control group(P < 0.05) and the group2 was the best. The abdominal fat weight and ratio in the group 1 were significantly higher than those in the control group and group 3(P < 0.05) and the tibia weight in the group 2 was significantly higher than that in the control group and group 1(P < 0.05); There were no significant differences in heart weight,liver weight and the gland stomach weight among all groups(P > 0.05). Spleen weight in test groups was significantly higher than that in the control group(P < 0.05). The bursa weight and muscular stomach weight in the group 2 were significantly higher than those in the control group and group 1(P < 0.05). In serum, total cholesterol, triglycerides, low-density lipoprotein and urea nitrogen in the group 2 were significantly lower comparing with those in the control group(P < 0.05). High-density lipoprotein in the group 2 was significantly higher than that in other groups(P < 0.05). There were no significant differences in total serum protein, albumin, globulin and albumin/globulin among all groups(P > 0.05). Alanine aminotransferase and aspartate transaminase(AST) in groups 2 and 3 were higher than those in the group1 and control group but not obvious(P > 0.05) and alkaline phosphatase(ALP) in groups 1 and 2 was higher than that in the control group and group 3(P > 0.05). It is concluded that alfalfa flavonoids extraction added in dietary feed improve the growth performance, organ development and blood biochemical indexes of Yangzhou geese. It is concluded that 300 mg/kg supplemental level of the dietary alfalfa flavonoids extraction is optimal in this experiment. | Yinyin Chen Xiaoxiao Gong Guodong Li Miao Lin Yongjiu Huo Shengli Li Guoqi Zhao | 2016 | Animal Nutrition2016，，4： | 14 |
| 4 | Effects of bamboo vinegar powder on growth performance and mRNA expression levels of interleukin-10,interleukin-22,and interleukin-25 in immune organs of weaned piglets显示文摘The aim of this study was to explore the effects of bamboo vinegar powder on growth performance,diarrhea situation and mRNA expression levels of cytokines i.e., interleukin-10(IL-10), interleukin-22(IL-22), and interleukin-25(IL-25) in immune organs of weaned piglets, and to accumulate theoretical data for the application of bamboo vinegar powder in weaned piglet production. Forty-five crossbred(Duroc × Landrace × Yorkshire, all male) weaned piglets with similar body weight(6.74 ± 0.17 kg) at 31 days of age were randomly assigned to 5 treatments with 3 replicates per treatment and 3 piglets in each replicate. The five treatments were as follows: CON(a basal diet), ANT(the basal diet + 0.12% antibiotics),BV1(the basal diet + 0.1% bamboo vinegar powder), BV5(the basal diet + 0.5% bamboo vinegar powder),BV10(the basal diet + 1.0% bamboo vinegar powder). This experiment lasted 35 days. The growth performance and diarrhea situation were recorded. The relative mRNA expression levels of IL-10, IL-22 and IL-25 in liver, spleen, duodenum and mesenteric lymph nodes were detected by real-time PCR. Feed:gain of BV5 was significantly lower than that of CON(P < 0.05). In comparison with CON, diarrhea rate and diarrhea index of BV1 and BV5 all tended to decrease(P < 0.1). Compared with CON, mRNA expression level of IL-10 in liver of ANT tended to be lower(P < 0.1) and these of BV1, BV5 and BV10 were significantly reduced(P < 0.05). The mRNA expression levels of IL-10 in duodenum of ANT, BV1, BV5 and BV10 were all lower than those of CON, of which BV10 had significantly decreased IL-10 mRNA expression in duodenum(P < 0.05). The mRNA expression levels of IL-22 in duodenum of ANT, BV1, BV5 and BV10 all tended to be inhibited compared with CON(P < 0.1). With the increase of bamboo vinegar powder dosage, mRNA expression levels of IL-25 in spleen and mesenteric lymph nodes of BV1, BV5 and BV10 tended to be up-regulated. Overall, bamboo vinegar powder could improve growth performance,and regulate mRNA expression levels of IL-10, IL-22 and IL-25 in immune organs of weaned piglets. The dosage at 0.5% showed optimum effects. | Yongjiu Huo Zhengxu Liu Han Xuan Chunbin Lu Lihuai Yu Wenbin Bao Guoqi Zhao | 2016 | Animal Nutrition2016，，2： | 11 |
| 5 | Deformation and damage features of a Re/Ru-containing single crystal nickel base superalloy during creep at elevated temperature显示文摘The deformation and damage features of a 4.5%Re/3.0%Ru-containing single crystal nickel-based superalloy during the creep in the temperature range of 1040–1070 °C and stress range of 137–180 MPa was investigated by means of creep properties measurement and contrast analysis of dislocation configuration. The results showed that the alloy exhibited a better creep resistance in the range of the testing temperatures and stresses, the deformation mechanism of the alloy during steady state creep was dislocations climbing over the rafted γ′ phase.In the latter period of creep, the deformation mechanism of the alloy was dislocations shearing into the rafted γ′phase. It is believed that the dislocations shearing into γ′ phase may cross-slip from {111} to {100} planes for forming the K-W locks to restrain the slipping and cross-slipping of dislocations on {111} plane. As the creep goes on, the alternate slipping of dislocations results in the twisted of the rafted γ′ phase to promote the initiation and propagation of cracks along the γ/γ′ interfaces up to creep fracture, which is considered to be the damage and fracture feature of alloy during creep at high temperature. | Guoqi Zhao Sugui Tian Shunke Zhang Ning Tian Lirong Liu | 2019 | Progress in Natural Science:Materials International2019，29，2： | 4 |
| 6 | The protective roles of tea tree oil extracts in bovine mammary epithelial cells and polymorphonuclear leukocytes显示文摘Background: Tea tree oil(TTO) plays an important role in antibacterial activity and alleviating the inflammatory responses. Bovine mammary epithelium and polymorphonuclear leukocytes(PMNL) can actively respond to bovine mastitis infection. However, regulatory effects of TTO extracts on the innate immune response of bovine mammary epithelial cells(BMECs) and PMNL remain not reported. Therefore, aim of the study was to evaluate the effects of TTO extracts on the m RNA levels of the genes involved in the innate immune response of BMECs and PMNL.Results: Our results demonstrated that addition of 0.025% and 0.05% TTO increased the proliferation of BMECs, and significantly enhanced(P < 0.05) the viability of BMECs exposed to Staphylococcus aureus(S. aureus). An inhibitory effect was observed against the growth of S. aureus by TTO incubation. The 0.05% TTO reduced S. aureus biofilm formation, association and invasion of S. aureus to BMECs, and changed the morphological and structural features of S. aureus. The proinflammatory cytokines IL-1β, IL-6, and TNF-α were decreased(P < 0.001) by the incubation of TTO. Interestingly, the expression of IL-8 known for PMNL chemotactic function was elevated(P < 0.05) by 0.05%TTO treatment. Consistently, 0.05% TTO increased the migration of PMNL in S. aureus-exposed BMECs when compared with S. aureus treatment alone(P < 0.05). In addition, PMNL incubated with 0.05% TTO decreased the levels of NFKB inhibitor alpha(NFKBIA) and TNF-α.Conclusions: Our results indicate that use of TTO can relieve the BMECs pro-inflammatory response caused by S.aureus and promote the migration of PMNL to mount the innate immune responses, and it may be novel strategy for the treatment of bovine mastitis caused by S. aureus. | Kang Zhan Tianyu Yang Baobao Feng Xinyu Zhu Yinyin Chen Yongjiu Huo Guoqi Zhao | 2020 | Journal of Animal Science and Biotechnology2020，11，4： | 3 |
| 7 | Timing of granite pegmatite-type high-purity quartz deposit in the Eastern Qinling,China:constraints from in-situ LA-ICP-MS trace analyses of quartz and monazite U–Pb dating显示文摘Eastern Qinling,China is one of the important rare metal metallogenic provinces with extensively distributed granite pegmatite dikes.The No.5 granite pegmatite intruded into the granitic gneiss of the Qinling Group,and the major minerals are quartz(39.8%),K-feldspar(18.8%),albite(36.3%),muscovite(3.4%),and garnet(1.1%).Monazite U–Pb isotopic dating indicates that the No.5 pegmatite from the Eastern Qinling was emplaced at ca.420.2±2.2 Ma,which confirms that highpurity quartz mineralization probably formed during the Early Devonian.In-situ laser ablation inductively coupled plasma mass spectrometry analysis of quartz show that quartz samples from Eastern Qinling have total trace element concentrations(Al,Ti,Sc,Li,B,Cr,Mn,and Fe)ranging from 23.2 to 52.8 ppm,slightly higher than the quartz(impurity element content from 13.4 to 25.9 ppm)of the Spruce Pine high-purity quartz deposit in western North Carolina.The No.5 pegmatite of Eastern Qinling could be defined as one high-purity quartz deposit of China. | Yong Zhang Haibo Zhao Lei Liu Jiayong Pan Likuan Zhu Guoqi Liu Xiaotian Zhang | 2022 | Acta Geochimica2022，41，2： | 2 |
| 8 | Sinian gas sources and effectiveness of primary gas-bearing system in Sichuan Basin, SW China显示文摘Based on correlation between geochemical characteristics of Sinian and Cambrian source rocks and discovered gas reservoirs,paleoand the analysis on geological conditions of reservoir formation,the sources of natural gas in the Sinian of Sichuan Basin have been discussed to sort out the contribution of Sinian source rocks to the gas reservoirs and effectiveness of Sinian primary gas-bearing system.Through the analysis of natural gas composition,carbon and hydrogen isotopes and effectiveness of Sinian accumulation assemblages,it is concluded that:(1)The natural gas derived from the Sinian source rock is characterized by low ethane content,heavy ethane carbon isotope and light methane hydrogen isotope,and obviously different from the gas generated by the Cambrian source rock.(2)The gas reservoirs discovered in Sinian Dengying Formation are sourced by Sinian and Cambrian source rocks,and the Sinian source rock contributes different proportions to the gas in the 4th member and the 2nd member of the Dengying Formation,specifically,39%and 55%to the 4th member in marginal zone and intra-platform,54%and 68%to the 2th member in the marginal zone and intra-platform respectively.(3)The effectiveness of the Sinian primary gas-bearing system depends on the gas generating effectiveness of the source kitchen,reservoir and combination of gas accumulation elements.For high-over mature marine source rocks at the Ro of less than 3.5%,besides gas generated from the thermal cracking of liquid hydrocarbon,the kerogen still has some gas generation potential by thermal degradation.In addition,the Sinian microbial dolomite still preserves relatively good-quality reservoirs despite large burial depths,which match well with other basic conditions for gas accumulation in central Sichuan paleo-uplift,increasing the possibility of Sinian primary gas-bearing system.The research results confirm that the Sinian primary gas-bearing system is likely to form large-scale accumulation. | ZHAO Wenzhi XIE Zengye WANG Xiaomei SHEN Anjiang WEI Guoqi WANG Zecheng WANG Kun | 2021 | Petroleum Exploration and Development2021，48，6： | 1 |
| 9 | Bovine serum albumin-imprinted polymer gels prepared by graft copolymerization of acrylamide on chitosan显示文摘 | FU Guoqi ZHAO Jichao YU Hao | 2007 | Reactive and Ftmctional Polymers2007，67，5： | 1 |
| 10 | Bovine serum albumin-imprinted polymer gels prepared by graft copolymerization of acrylamide on chitosan 显示文摘 | FU Guoqi ZHAO Jichao YU Hao | 2007 | Reactive & Functional Polymers2007，67，： | 1 |
| 11 | Treatment of the wastewater containing low-level 241 Am using flocculation-microfiltration process显示文摘 | Gao Yong Zhao Jun Zhang Guanghui Zhang Dong Cheng Weiwen Yuan Guoqi Liu Xuejun Ma Bangzhong Zeng Junhui Gu Ping | 2004 | Separation and Purification Technology2004，，2： | 1 |
| 12 | Comparative proteomic analysis of cold responsive proteins in two wheat cultivars with different tolerance to spring radiation frost显示文摘Spring radiation frost(SRF)is a severe environmental stress which impairs wheat yield and productivity worldwide.To better understand the mechanism of wheat(Triticum aestivum)responding to SRF,a comparative proteomic analysis was performed to analyze the changes of the key proteins in two wheat cultivars Jimai22 and Luyuan301 with high and low tolerance to SRF respectively.A total of 43 differentially expressed proteins(DEPs)which mainly involved in carbohydrate metabolism,amino acid metabolism,resistance proteins and antioxidant enzymes,photosynthesis and cellular respiration proteins,cell-wall related proteins,protein translation/processing/degradation and signal transduction were isolated and identified by two-dimensional electrophoresis and MALDI-TOF-TOF MS.The results revealed that of the 21 DEPs in Jimai22 responding to the SRF,13 DEPs were upregulated and 8 DEPs were downregulated,and that of the 22 DEPs in Luyuan301,9 DEPs were upregulated and 13 DEPs were downregulated.These DEPs might be responsible for the stronger cold resistance of Jimai22 compared to Luyuan301.The expression pattern and function analysis of these DEPs were very significant to understanding the mechanism of the SRF responses in wheat. | Shujuan ZHANG Guoqi SONG Yulian LI Jie GAO Jiao WANG Guiju CHEN Haosheng LI Genying LI Zhendong ZHAO | 2014 | Frontiers of Agricultural Science and Engineering2014，1，1： | 1 |
| 13 | The mineralogy, petrology, metamorphic PTDt trajectory and exhumation mechanism of blueschists, south Tianshan, northwestern China显示文摘 | Jun Gao Guoqi He Maosong Li Xuchang Xiao Yaoqing Tang Jun Wang Min Zhao | 1995 | Tectonophysics1995，，1： | 1 |
| 14 | Identification and mapping of pm2026: a recessive powdery mildew resistance gene in an einkorn (Triticum monococcum L.) accession显示文摘 | Hongxing Xu Guoqi Yao Li Xiong Lili Yang Yumei Jiang Bisheng Fu Wenfang Zhao Zhengzhi Zhang Caiqin Zhang Zhengqiang Ma | 2008 | Theoretical and Applied Genetics2008，，4： | 1 |
| 15 | Al elopathic Effects of Melilotus officinalis Desr. against Weeds显示文摘In this study,the allelopathic effects of 100 g / L water extract of Melilotus officinalis Desr. on seed germination and seedling growth of Melilotus officinalis Desr.,Trifolium pretense L.,Medicago sativa L. cv. Victoria,Echinochloa crusgalli( L.) Beauv.,Lxeris chinensis( Thunb.) Nakai and Plantago asiatica L.were investigated by biological assay. Dried powder of Melilotus officinalis Desr. was applied to the field in spring and winter to verify the inhibitory effects of Melilotus officinalis Desr. on weed biomass in the experimental field and compare the effects between Melilotus officinalis Desr. and a variety of commonly used chemical herbicides on weed suppression. The results showed that water extract of Melilotus officinalis Desr. posed significant effects on seed germination and seedling growth of Trifolium pretense L.,Echinochloa crusgalli( L.) Beauv.,Lxeris chinensis( Thunb.) Nakai,Plantago asiatica L.,Melilotus officinalis Desr. and Medicago sativa L. cv. Victoria,exhibiting strong allelopathic effects,but the inhibition rate varied greatly among different plant species. Therefore,the allelopathic effects of Melilotus officinalis Desr. should be utilized appropriately in practical applications. Dried powder of Melilotus officinalis Desr. significantly reduced weed quantity in the field for a short duration,which should be administered multiple times in a sufficient amount for weed control in the production. | Caixia WU Sujiao LIU Guoqi ZHAO Jie NI | 2015 | Agricultural Biotechnology2015，4，6： | 1 |
| 16 | Differential Responses Between Monocytes and Monocyte-Derived Macrophages for Lipopolysaccharide Stimulation of Calves显示文摘由 lipopolysaccharide (LPS ) 在单核白血球和导出单核白血球的巨噬细胞在这试验像使用费的受体表示模式刺激被检验。颈部的静脉的血从四头日本小牛被收集,并且外部血 mononuclear 房间(PBMC ) 被孤立。房间直接被使用由磁性的房间排序收集单核白血球或为 7 天到有教养在 Repcell 收集导出单核白血球的巨噬细胞。然后,我们为 24 h 在 LPS 刺激以后在单核白血球和导出单核白血球的巨噬细胞分析了 TLR 和 cytokines 的 mRNA 表示模式。单核白血球和导出单核白血球的巨噬细胞的 LPS 刺激为 TNF- , IL-6 和 IL-8 导致了 mRNA 抄本的层次的增加。而且, TNF-6 和 IL-6 mRNA 表情被 LPS 刺激显著地在导出单核白血球的巨噬细胞扩充。TLR mRNA 表情在单核白血球的 LPS 刺激以后是未改变的,当在导出单核白血球的巨噬细胞的 TLR mRNA 表情是复杂的时。TLR1, 3, 5, 8 和 10 显著地在 LPS 刺激以后被减少,在 TLR2 的 mRNA 表情没有差别, 4, 6 和 7 在控制和 LPS 刺激的组之间。而且, TLR9 的表示都没被发现。作为介绍房间的抗原,单核白血球和导出单核白血球的巨噬细胞对 LPS 不同地作出回应,因此他们可以在天生的免疫系统有不同功能。 | Yijie Guo Guoqi Zhao Sachi Tanaka Takahiro Yamaguchi | 2009 | Cellular & Molecular Immunology2009，6，3： | 1 |
| 17 | Two-step colloidal synthesis of micron-scale Bi_(2)O_(2)Se nanosheets and their electrostatic assembly for thin-film photodetectors with fast response显示文摘Recently discovered bismuth oxychalcogenide(Bi_(2) O_(2) Se) has aroused great interest due to its ultrahigh carrier mobility,tunable band gap and good environmental stability,making it a promising candidate for high-performance electronics and optoelectronics.Their synthesis by colloidal approaches represents a cost-effective alternative to well-established chemical vapor deposition methods,and the resulting electronic-grade inks are important for large-area printed or wearable electronics.However,it is still challenging to control the colloidal growth of Bi_(2) O_(2) Se nanosheets in solution in addition to their assembly into high-performance thin films.Here,we report a two-step colloidal synthesis of Bi_(2) O_(2) Se nanosheets by separating the seeding and growth steps,thereby achieving controllable production of nanosheets with a lateral size of 1.4 mm and a thickness of 10 nm at optimized reaction conditions.These Bi_(2) O_(2) Se nanosheets are electrostatically assembled into large-area thin films,from which a photodetector is fabricated with a responsivity of 6.1 A/W and a short response time of 368 ms under the 520-nm laser illumination.The device exhibits fast response to modulations as high as 100 k Hz,along with a à3 dB bandwidth of 1 kHz.This work provides an important understanding of the controlled colloidal synthesis of Bi_(2) O_(2) Se nanosheets,and demonstrates their potential applications in fast photodetectors. | Xixi Pang Yingtao Zhao Xiangxiang Gao Guoqi Wang Hao Sun Jun Yin Jian Zhu | 2021 | Chinese Chemical Letters2021，32，10： | 1 |
| 18 | Words in the Paintiongs:Living Well显示文摘This book serves as a stage for historical background,structured around the crafting process of Pingyang woodblock New Year paintings.Through material selection,sketching,carving,coloring,and printing,it vividly interprets the splendor and vicissitudes experienced by Pingyang woodblock New Year paintings throughout history.Utimately,it depicts how they found renewed life,carrying the essence and soul of the nation. | Zhu Yiwen Zhao Guoqi | 2024 | China Book International2024，，1： | 0 |
| 19 | Alloy-induced reduction and anisotropy change of lattice thermal conductivity in Ruddlesden–Popper phase halide perovskites显示文摘The effective modulation of the thermal conductivity of halide perovskites is of great importance in optimizing their optoelectronic device performance.Based on first-principles lattice dynamics calculations,we found that alloying at the B and X sites can significantly modulate the thermal transport properties of 2D Ruddlesden−Popper(RP)phase halide perovskites,achieving a range of lattice thermal conductivity values from the lowest(κ_(c)=0.05 W·m^(−1)·K^(−1)@Cs_(4)AgBiI_(8))to the highest(κ_(a/b)=0.95 W·m^(−1)·K^(−1)@Cs4NaBiCl_(4)I_(4)).Compared with the pure RP-phase halide perovskites and three-dimensional halide perovskite alloys,the two-dimensional halide perovskite introduces more phonon branches through alloying,resulting in stronger phonon branch coupling,which effectively scatters phonons and reduces thermal conductivity.Alloying can also dramatically regulate the thermal transport anisotropy of RP-phase halide perovskites,with the anisotropy ratio ranging from 1.22 to 4.13.Subsequently,analysis of the phonon transport modes in these structures revealed that the lower phonon velocity and shorter phonon lifetime were the main reasons for their low thermal conductivity.This work further reduces the lattice thermal conductivity of 2D pure RP-phase halide perovskites by alloying methods and provides a strong support for theoretical guidance by gaining insight into the interesting phonon transport phenomena in these compounds. | Huimin Mu Kun Zhou Fuyu Tian Yansong Zhou Guoqi Zhao Yuhao Fu Lijun Zhang | 2023 | Frontiers of physics2023，18，6： | 0 |
| 20 | Butyrate inhibits the bovine rumen epithelial cell proliferation via downregulation of positive regulators at G0/G1 phase checkpoint显示文摘Short-chain fatty acids(SCFAs)butyrate promote the postnatal rumen epithelial development and maturation in ruminants.However,molecular mechanisms of effects of butyrate on the bovine rumen epithelial cells(BRECs)proliferation remain elusive.Therefore,purpose of this study was to investigate the effects of butyrate on the expression of genes and proteins at G0/G1 and S phase of BRECs cycle.Our results showed that BRECs treated with butyrate inhibited(P<0.05)the proliferation of BRECs,relatively to control.Flow cytometric assays revealed that butyrate triggers the BRECs cycle arrest at the G0/G1 phase.qRT-PCR analyses of mRNA level of genes involved in the G0/G1 phase of cell cycle showed that butyrate significantly upregulated(P<0.001)the expression of mRNA encoding p21^(Cip1)compared with control group,but it decreased(P<0.05)the mRNA levels of cyclin D1 and CDK4 genes at G0/G1 phase checkpoint compared with control.Moreover,Western blot also revealed that butyrate downregulated the expression of cyclin D3,CDK6,p-Rb,and E2F1 proteins involved in the modulation of G0/G1 phase of cell cycle.In conclusion,our results demonstrated that butyrate inhibits the proliferation of BRECs via downregulation of positive regulators at G0/G1 phase checkpoint. | KANG ZHAN MAOCHENG JIANG TIANYU YANG ZIXUAN HU GUOQI ZHAO | 2022 | BIOCELL2022，46，7： | 0 |
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