|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency显示文摘Pluripotency,一个细胞的能力区分并且产生所有胚胎的系,定义象胚胎的茎(ES ) 那样的哺乳动物的细胞类型的一个小数字细胞。当它通常被保持了时,那 pluripotency 是 transcriptional 的产品激活并且维持关键干细胞基因的表达式的规章的网络,积累的证据在建立并且保卫 ES 房间的 pluripotency 为 epigenetic 进程正在指向一个关键角色,象维持区分的房间类型的身份一样。以便更好在 pluripotency 理解 epigenetic 机制的角色,我们检验了在经历区别进一个 mesendodermal 系的人的 ES 房间(hESCs ) 染色体宽的染色质修正的动力学。我们发现在倡导者的染色质修正在区别期间仍然保持大部分不变,除了在在在 H3K27 的 acetylation 和 methylation 之间的一个动态开关标记在基因表示的激活和 silencing 之间的转变的倡导者的一个小数字,建议在在大多数差别上的房间命运承诺的一个层次表示了基因。我们也在 50 000 潜在的 enhancers 上印射,并且在染色质修正,特别 H3K4me1 和 H3K27ac 观察了大得多的动力学,它与他们的潜在的目标基因的表示相关。这些 enhancers 的进一步的分析揭示了 pluripotency 和可以在 hESCs 授与发展胜任的一个平衡状态的一口染色质签名陈述语气的潜在地关键的 transcriptional 管理者。我们的结果提供在定义 enhancers 和 pluripotency 支持染色质修正的角色的新证据。 | R David Hawkins Gary C Hon Chuhu Yang Jessica E Antosiewicz-Bourget Leonard K Lee Que-Minh Ngo Sarit Klugman Keith A Ching Lee E Edsall Zhen Ye Samantha Kuan Pengzhi Yu Hui Liu Xinmin Zhang Roland D Green Victor V Lobanenkov Ron Stewart James A Thomson Bing Ren | 2011 | Cell Research2011，21，10： | 6 |
| 2 | Structure-activity relationships in flexible protein domains: regulation of rho GTPases by RhoGDI and D4 GDI 1 1 Edited by P. E. Wright显示文摘 | Alexander P. Golovanov Tsung-Hsien Chuang Celine DerMardirossian Igor Barsukov Dawn Hawkins Ramin Badii Gary M. Bokoch Lu-Yun Lian Gordon C.K. Roberts | 2001 | Journal of Molecular Biology2001，，1： | 1 |
| 3 | Physiological responses of lactating dairy cattle to pelleted corn and oats显示文摘 | Hawkins George E Gary E Parr | 1963 | Journal of Dairy Science1963，46，： | 1 |
| 4 | The suffixing preference: a processing explanation显示文摘 | ANNE CUTLER JOHN A. HAWKINS GARY GILLIGAN | 2009 | Linguistics2009，，5： | 1 |
| 5 | Distinct Epigenomic Landscapes of Pluripotent and Lineage-Committed Human Cells显示文摘 | R. David Hawkins Gary C. Hon Leonard K. Lee QueMinh Ngo Ryan Lister Mattia Pelizzola Lee E. Edsall Samantha Kuan Ying Luu Sarit Klugman Jessica Antosiewicz-Bourget Zhen Ye Celso Espinoza Saurabh Agarwahl Li Shen Victor Ruotti Wei Wang Ron Stewart James A. | 2010 | Cell Stem Cell2010，，5： | 1 |
| 6 | Assessing Relative Risks of Infection and Rejection: A Meta-analysis using an Immune Function Assay显示文摘 | Richard J. Kowalski Diane R. Post Roslyn B. Mannon Anthony Sebastian Harlan I. Wright Gary Sigle James Burdick Kareem Abu Elmagd Adriana Zeevi Mayra Lopez-Cepero John A. Daller H Albin Gritsch Elaine F. Reed Johann Jonsson Douglas Hawkins Judith A. Britz | 2006 | Transplantation2006，，5： | 1 |
| 7 | Applying plant-based irrigation scheduling to assess water use efficiency of cotton following a high-biomass rye cover crop显示文摘Background:This study addressed the potential of combining a high biomass rye winter cover crop with predawn leaf water potential(ΨPD)irrigation thresholds to increase agricultural water use efficiency(WUE)in cotton.To this end,a study was conducted near Tifton,Georgia under a manually-controlled,variable-rate lateral irrigation system using a Scholander pressure chamber approach to measure leaf water potential and impose varying irrigation scheduling treatments during the growing season.ΨPDthresholds were-0.4 MPa(T1),-0.5 MPa(T2),and-0.7 MPa(T3).A winter rye cover crop or conventional tillage were utilized for T1-T3 as well.Results:Reductions in irrigation of up to 10%were noted in this study for the driest threshold(-0.7 MPa)with no reduction in lint yield relative to the-0.4 MPa and-0.5 MPa thresholds.Drier conditions during flowering(2014)limited plant growth and node production,hastened cutout,and decreased yield and WUE relative to 2015.Conclusions:We conclude thatΨPDirrigation thresholds between-0.5 MPa and-0.7 MPa appear to be viable for use in aΨPDscheduling system with adequate yield and WUE for cotton production in the southeastern U.S.Rye cover positively impacted water potential at certain points throughout the growing season but not yield or WUE indicating the potential for rye cover crops to improve water use efficiency should be tested under longer-term production scenarios. | MEEKS Calvin D SNIDER John L CULPEPPER Stanley HAWKINS Gary | 2020 | Journal of Cotton Research2020，3，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员