|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Design, Synthesis, and Biological Activity of Novel Aromatic Amide Derivatives Containing Sulfide and Sulfone Substructures显示文摘In recent years,the damage caused by soil nematodes has become increasingly serious;however,the varieties and structures of the nematicides available on the market are deficient.Fluopyram,a succinate dehydrogenase inhibitor(SDHI)fungicide developed by Bayer AG in Germany,has been widely used in the prevention and control of soil nematodes due to its high efficiency and novel mechanism of action.In this paper,two series of novel target compounds were designed and synthesized with nematicidal and fungicidal fluopyram as the molecular skeleton in order to introduce sulfide and sulfone substructures.The structures were identified and characterized by 1H nuclear magnetic resonance(NMR),13C NMR,and high-resolution mass spectrometer(HRMS).The bioassays revealed that most of the compounds showed excellent nematicidal activities at 200 lgmL-1 in comparison with fluopyram,while the nematode mortality rate dropped sharply at 100μg·mL-1,except for compounds I-11 and II-6.In terms of fungicidal activity,compound I-9 was discovered to have an excellent inhibitory rate,and a molecular docking simulation was performed that can provide important guidance for the design and exploration of efficient fungicidal lead compounds. | Xuewen Hua Nannan Liu Sha Zhou Leilei Zhana Hao Yin Guiqing Wang Zhijin Fan Yi Mac | 2020 | Engineering2020，6，5： | 4 |
| 2 | Synthesis of Osthole Derivatives with Grignard Reagents and Their Larvicidal Activities on Mosquitoes显示文摘osthole 的结构被修改了对蚊子改进它的 larvicidal 活动。有 Grignard 试剂的 osthole 衍生物的新有效合成被开发了,它作为倡导者采用 CuI 和 LiCl 并且盖住大量底层负担得起相应产品在对好收益(多达 83%) 温和。简历活动评估证明几个产品比 osthole 展出了更好的活动。 | Ming Liu Yang Liu Xuewen Hua Changchun Wu Sha Zhou Baolei Wang Zhengming Li | 2015 | Chinese Journal of Chemistry2015，33，12： | 4 |
| 3 | Design, Synthesis and Herbicidal Activity of Novel Sulfonylureas Containing Tetrahydrophthalimide Substructure显示文摘 | HUA Xuewen ZHOU Sha CHEN Minggui ZHANG Dongkai LIU Ming LIU Jingbo WU Changchun LIU Yang LI Yonghong LI Zhengming | 2016 | Chemical Research in Chinese Universities2016，32，3： | 3 |
| 4 | Design, Synthesis and Insecticidal Evaluation of Anthranilic Diamides Containing Optically Pure Amino Acid Moiety显示文摘N-pyridylpyrazolecarboxamide 衍生物的二个系列被介绍 D 丙氨酸酸酉旨和 D 丝氨酸酸酉旨进 chlorantraniliprole 的骨骼设计并且综合。获得的结构被 1 H NMR, 13 C NMR,元素的分析和特定的光旋转分析。初步的生物鉴定显示一些混合物与 chlorantraniliprole 比较对分开的 Mythimna 和 Plutella xylostella 显示了优秀杀虫的活动。特别地, IIq 在 0.01 mg·L −1 与 90% 的死亡率对 Plutella xylostella 显示出优秀杀虫的活动。A 3D-QSAR (CoMSIA ) 学习被执行以便揭示杀虫的结构活动关系并且显示未来工作。CoMSIA 学习证明在 pyrazole 的 3 位置的缺乏的组打电话找的大候补选手和电子是有利的,与氨基酸的酉旨组附近的一个小组一样。 | Shaa Zhou Sha Zhou Xuewen Hua Wei Wei Yongtao Xie Minggui Chen Xiangde Meng Ming Liu Lixia Xiong Na Yang Baolei Wang Zhengming Li | 2016 | Chinese Journal of Chemistry2016，34，12： | 2 |
| 5 | Research on controllable alkaline soil degradation of 5-substituted chlorsulfuron显示文摘Sulfonylurea(SU) has become one class of the most important herbicides worldwide due to their ultralow application rate and mammalian toxicity. Recently application licenses of 3 classical SU herbicides chlorsulfuron, metsulfuron-methyl and ethametsulfuron were suspended due to their undesirable long persistence which is incompatible with the particular rotation planting system in China. Our previous study has discovered that electron-donating groups, especially dimethylamino and diethylamino substituents, on the 5 th position of the benzene ring in chlorsulfuron, greatly accelerated its degradation rate in an acidic soil(p H 5.41). Owing to the natural slower degradation of SUs in alkaline soil,dimethylamino and diethylamino substituted chlorsulfuron Ia and Ib were further studied in an alkaline soil(p H 8.46) with chlorsulfuron as a control. The experimental data indicated that the half-life of degradation(DT_(50)) of Ia was 3.36 days while Ib was 6.25 days which amounted to 30 and 15 folds faster than chlorsulfuron(DT_(50)84.53 days), respectively. The research confirmed that our newly-designed structures Ia and Ib can hasten their degradation rate in alkaline soil as well as in acidic soil. This structural modification of the classical SU provided an opportunity to control the degradation rate to reduce their impact on relevant environment and ecology. | Shaa Zhou Xuewen Hua Wei Wei Minggui Chen Yucheng Gu Sha Zhou Haibin Song Zhengming Li | 2018 | Chinese Chemical Letters2018，29，6： | 2 |
| 6 | Controllable Effect of Structural Modification of Sulfonylurea Herbicides on Soil Degradation显示文摘在与他们的不同结构的属性的关系的 sulfonylurea 除草剂的土壤降级行为的学习是为我们重要的最大可能理解新 eco 友好的除草剂的发展。化学结构的结构的修正能在土壤影响他们的降级率,这被要求。九设计结构被综合分别地学习他们的 herbicidal 活动以及他们的土壤降级行为。新奇混合物 I-3-I-7 被描绘由紫外, 1 H NMR 和 13 C NMR, MS 和 EA。生物鉴定显示大多数目标混合物与 Chlorsulfuron 比较显示了优异 herbicidal 活动。土壤降级结果进一步证实了我们以前的假设在 5 苯戒指的 th 位置清楚地增加了他们的降级率, dimethylamino 和 diethylamino 组能以更有利的地位在之中调整降级率。 | Xuewen Hua Shaa Zhou Minggui Chen Wei Wei Ming Liu Kang Lei Sha Zhou Yonghong Li Baolei Wang Zhengming Li | 2016 | Chinese Journal of Chemistry2016，34，11： | 2 |
| 7 | Design, Synthesis, Antifungal Activities and SARs of (R)-2-Aryl-4,5-dihydrothiazole-4-carboxylic Acid Derivatives显示文摘基于自然产品 2-aryl-4,5-dihydrothiazole-4-carboxylic 酸的结构,一系列新奇(R)-2-aryl-4,5-dihydrothiazole-4-carboxylic 酸衍生物被设计并且综合。他们的结构被 1 H NMR, 13 C NMR 和 HRMS。复合 9b 的单个水晶结构被 X 光检查衍射分析决定。抗真菌的活动第一次被评估。生物鉴定结果显示展出的大多数混合物节制到好抗真菌的活动。复合 13a 的抗真菌的活动(对 Cercospora arachidicola Hori ) , 13d (对 Alternaria solani ) ,并且 16e (对 Cercospora arachidicola Hori ) 分别地,是 61.9% , 67.3% 和 61.9% 它比商业杀真菌剂 chlorothalonil 和 carbendazim 的那些高。而且,复合 13d 对测试的 7 种真菌展出了优秀抗真菌的活动(66.7% , 77.3% , 63.0% , 87.9% , 70.0% , 70.0% 和 80.0% 在 50 µg ? mL ) 。因此, 13d 能为抗真菌的代理人的发展被用作新铅结构。 | Jingbo Liu Yuxin Li Youwei Chen Xuewen Hua Yingying Wan Wei Wei Haibin Song Shujing Yu Xiao Zhang Zhengming Li | 2015 | Chinese Journal of Chemistry2015，33，11： | 2 |
| 8 | Design, Synthesis and Fungicidal Activity of Novel Strobilurin-l,2,4-Triazole Derivatives Containing Furan or Thiophene Rings显示文摘A series of strobilurin-l,2,4-triazole derivatives containing a furan or thiophen ring was designed andsynthesized. The structures of the compounds were characterized by 1H NMR, 13C NMR and HRMS spectra. Thebioassays indicated that the fungicidal activities of compounds 10b(EC50=14.82 mg/L) and 10c(EC50=18.72 mg/L)against Cercospora arachidicola Hori in vitro were much higher than that of Azoxystrobin as control(EC50=40.54mg/L) and the fungicidal activities of compounds 10u(EC50=8.66 rag/L) and 10n(EC50=9.89 rag/L) against Rhizotoniacerealis in vitro were higher than that of the same control(EC50=10.86 rag/L). Compounds 10b, 10c, 1011 and 10kcould be considered as the leading compounds for further investigation. | LIU Yang LIU Ming ZHANG Dongkai HUA Xuewen WANG Baolei ZHOU Sha LI Zhengming | 2016 | Chemical Research in Chinese Universities2016，32，6： | 1 |
| 9 | Synthesis and Bioactivity Evaluation of Novel N-Pyridylpyrazolemethanamine Derivatives显示文摘 | HUA Xuewen WEI Wei ZHU Liangliang ZHOU Yunyun | 2018 | Chemical Research in Chinese Universities2018，34，5： | 1 |
| 10 | Design, Synthesis, Structure-Activity Relationship and Insecticidal Activities of Trifluoromethyl-Containing Sulfiliminyl and Sulfoximinyl Phthalic Acid Diamide Structure显示文摘Due to a novel mode action,low toxicity to mammals and low residue characteristics,phthalic acid diamides have aroused considerable interests in agricultural chemistry.With introduction of N-cyano,N-trifluoroacetyl,N-carbamoylsulfiliminyl and sulfoximinyl substituents into phthalamides,12 novel derivatives containing trifluoromethyl moiety were designed and synthesized.All title compounds were characterized by ^(1)H NMR and high-resolution mass spectrometry.The preliminary results of biological activity assessment indicated that some title compounds exhibited moderate to good insecticidal activities against oriental armyworm(Pseudaletia separata Walker).In particular,Va gave higher activity against oriental armyworm and diamondback moth.The present work reported that the new trifluoromethylated diamides incorporating N-trifluoroacetylsulfoximinyl moieties are potential lead compounds for further structure optimization,providing some insight into the relating structure-activity relationship. | Sha Zhou Tao Yan Sha Zhou Xuewen Hua Baolei Wang Yucheng Gu Lixia Xiong Yongqiang Li Zhengming Li | 2014 | Chinese Journal of Chemistry2014，32，7： | 1 |
| 11 | Design, Synthesis and Herbicidal Activity of Novel Sulfonylureas Containing Triazole and Oxadiazole Moieties显示文摘 | ZHANG Dongkai HUA Xuewen LIU Ming WU Changchun WEI Wei LIU Yang CHEN Minggui ZHOU Sha LI Yonghong LI Zhengming | 2016 | Chemical Research in Chinese Universities2016，32，4： | 1 |
| 12 | Design, Synthesis and Insecticidal Evaluation of Novel N-Pyridylpyrazolecarboxamide Derivatives Containing Isoxazole, Isoxazoline and 1,3,4-Thiadiazole Rings显示文摘 | HUA Xuewen LIU Chen ZHOU Sha CHEN Minggui XIONG Lixia LI Yongqiang LI Zhengming | 2017 | Chemical Research in Chinese Universities2017，33，6： | 1 |
| 13 | Vibration coupling effects between two concentric cylindrical shells through periodic annular plates and entrained fluid显示文摘有象乘火车的液体一样的周期的环形的盘子的二同心的圆柱的壳上的联合效果理论上被调查。为由环形的盘子的反应力量的表情在仅仅伪纵的波浪在环形的盘子中存在的假设上被导出,为外部壳的分析表情被开发。到为一个舱模型的测量数据的无限的二墙的圆柱的壳的数字结果的比较在好同意。数字结果为由于声学的液体分析装载的特征被介绍并且周期的环形的盘子,和他们对外部壳的远领域的影响声学的放射。 | YIN Xuewen WANG Gongxian HUA Hongxing SHEN Rongying | 2010 | Chinese Journal of Acoustics2010，29，4： | 1 |
| 14 | Design, Synthesis and Biological Activities of Novel 4,5-Disubstituted-3-S-(β-D-acetylglycosyl)- 1,2,4-triazole Derivatives显示文摘 | CHENG Dandan WEI Wei LI Yuxin HUA Xuewen ZHOU Yunyun LIU Jingbo LI Yonghong YU Shujing XIONG Lixia LI Zhengming | 2017 | Chemical Research in Chinese Universities2017，33，5： | 0 |
| 15 | Structure and enhanced dielectric temperature stability of BaTiO3- based ceramics by Ca ion B site-doping显示文摘Capacitor is an important part of many electronic devices,so the temperature stability as one key parameter of capacitor needs to be improved constantly for meeting the requirements of various application temperature.Here,combined with the X-ray diffraction(XRD),selected area electron diffraction(SAED)and Vienna Ab-initio Simulation Package(VASP)calculation,it was confirmed that Ca ion can substitute the Ti site in the BaTi1-xCaxO3-x[BTC100](0≤x≤0.05)ceramics synthesized by solid-phase method which greatly improved the low-temperature stability of dielectric constant.Moreover,introducing Bi3þand Zn^(2+) into BTC4 to form(1-y)BaTi0.6Ca0.04O2.96-yBi(Zn_(0.5)Ti_(0.5))O_(3)[(1-y)BTC4-yBZT](0.1≤y≤0.2)ceramics can further improve the dielectric-temperature stability by means of diffused phase transition and core-shell structure.Most importantly,the 0.85BTC4-0.15BZT ceramics with a pseudocubic perovskite structure possessed a temperature coefficient of capacitance at 25℃(TCC25℃)being less than±15%over a wide temperature range of 55℃-200℃and a temperate dielectric constant(ε=1060)and low dielectric loss(tanδ=1.5%),which measure up to the higher standard in the current capacitor industry such as X9R requirements. | Xuewen Jiang Hua Hao Yang Yang Enhao Zhou Shujun Zhang Ping Wei Minghe Cao Zhonghua Yao Hanxing Liu | 2021 | Journal of Materiomics2021，7，2： | 0 |
| 16 | Design, Synthesis, and Insecticidal Activities of Novel Pyranoside Derivatives Targeting at Potential Second Calcium Channel IP3 Receptor显示文摘以便与行动的新模式寻找有势力和环境友好杀虫药剂,一系列 pyranoside 衍生物 mimicking D-myo-inositol 1,4,5-trisphosphate (IP 3) 根据 bioisosteric 途径被设计并且综合。生物试金对东方粟蚕(Mythimna separata ) 和有菱形斑纹的蛾(Plutella xylostella ) 显示了对好杀虫的活动中等的显示出的新混合物的那个大多数。特别,复合 5g 在 50 mg/L 对东方粟蚕显示了 80% larvicidal 活动。同时, 5a 分别地在 50 和 25 mg/L 对有菱形斑纹的蛾显示出 100% 和 70% larvicidal 活动。为了推进,探索行动的模式,钙成像技术被使用在细胞内部的钙离子集中上学习 5a, 5g,和 5i 的效果([Ca 2+] 在从 Spodoptera exigua 孤立的中央神经原的 i ) 。结果显示测试混合物免除了存储的钙离子 endoplasmic 蜂窝胃。 | Changchun Wu Yuxin Li Ming Liu Jingbo Liu Xuewen Hua Dongkai Zhang Lixia Xiong Na Yang Baolei Wang Zhengming Li | 2016 | Chinese Journal of Chemistry2016，34，11： | 0 |
| 17 | Synthesis and Herbicidal Activity of 3-Acetyl-4-hydroxy-2,1-benzothiazine Derivatives显示文摘In order to develop a novel herbicide containing the 2,1-benzothiazine motif, a series of 3-acetyl-4- hydroxy-2,1-benzothiazine derivatives was synthesized. All the target compounds were confirmed by 1H NMR,13C NMR, and high-resolution mass spectrometry(HRMS).In addition,the crystal structure of compoimd T27 was detemiined by single crystal X-ray diflraction. The bioassay results showed that some of the 3-acetyl-4-hydroxy- 2,1-benzothiazine derivatives(T13, T15, T22, and T24) showed good herbicidal activity at a dosage of 100 pg/mL. Among them,compounds T22 and T24 showed promising post-emergent herbicidal activities against Brassica campestris and Amaranthus retroflexus even at a dosage of 375 g/ha(1ha=104 m^2) in the greeiiliouse test. Studies on the structure-activity relationship demonstrated that the type of acetyl group played an important role in the herbicidal activity, and that the introduction of a phenoxyacetyl group at the 3-position of 2,1-beiizothiazine was beneficial in improving the herbicidal activity. The present study also indicated that 3-phenoxyacetyl-4-hydroxy-2,1-benzothiazine could be a potential lead compound for fiirther development of novel 2,1 -benzothiazine-containing herbicides. | LEI Kang LIU Yang WANG Shiben SUN Bin HUA Xuewen XU Xiaohua | 2019 | Chemical Research in Chinese Universities2019，35，4： | 0 |
| 18 | Energy Band-gap Calculation of d-Ta_2O_5 Using sX-LDA and B3LYP Methods显示文摘The energy band-gap and related factors of tantalum pentoxide with hexagonal phase were investigated using hybrid functional B3 LYP and s X-LDA methods. The results showed that both s X-LDA and B3 LYP techniques reveal the indirect semiconductor nature of δ-Ta2O5, whereas the obtained value of energy band-gap is much higher than previous theoretical reports but closer to the experimental data. The optical bandgap of δ-Ta2O5 is expected to originate from the O 2p→Ta 5d transition which may benefit from the d-s-p hybridization. | 张光磊 GUO Xiaoyu LI Xuewen QIN Guoqiang FU Hua | 2015 | Journal of Wuhan University of Technology(Materials Science)2015，30，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员