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| 1 | The preliminary efficacy of interferon-α and ribavirin combination treatment of chronic hepatitis C in HIV-infected patients显示文摘Background It is internationally accepted that in drug-nave individuals with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) co-infection, chronic hepatitis C should be treated first if the CD4 cell count does not require the initiation of anti-retroviral therapy. Present paper evaluated the clinical effect and side-effect of interferon-α (IFN-α) and ribavirin (RBV) combination therapy for Chinese patients with HCV-HIV co-infection, and compared with them for HIV infection alone. Methods Ten patients with HCV-HIV and 17 patients with HCV received 5 million unit IFNα-2b every other day intramuscularly, and 300 mg RBV triple daily by oral. Dynamic observations were made for HCV RNA and HIV RNA loads, CD4^+ and CD8^+ T lymphocyte counts, liver function and blood cell measurement, and the medicine side-effects. Results After 12-week and 24-week treatments of IFN-α and RBV combination therapy, mean HCV RNA levels reduced 1.14 logs and 1.56 logs from the baseline at week 0 in HCV-HIV co-infection, and reduced 1.48 logs and 1.75 logs in HCV infection, respectively. The HIV RNA levels decreased 1.22 logs and 1.32 logs from the base line; however, there were no obvious different changes at T lymphocyte counts of HCV-HIV and HCV patients through 24-week treatments. Whole 27 patients showed satisfactory biochemical response to therapy. There were some mild or mediate influence-like symptoms, intestinal uncomfortable and depressed blood cell counts in early stage of the treatments. No neuropsychiatric and auto-immune disorders were found. Conclusions IFN-α and RBV combination therapy had similar anti-HCV effects during 24-week treatment for HCV-HIV and HCV infected Chinese patients, and some anti-HIV effect. There were no obvious different biochemical responses and side-effects between two groups above. | ZHENGYu-huang ZHANGChun-ying HEYan ZHOUHua-ying ZOUWen DINGPei-pei HUANGLi LIHui | 2005 | Chinese Medical Journal2005,,14: | 2 |
| 2 | Portability of WSN sensor driver using abstraction layer and FSM 显示文摘 | Song Yin Li Huangli Zhao Hong | 2011 | Applied Mechanics and Materials2011,,44: | 1 |
| 3 | Photosensitive YBCO gel film and its patterning by sol - gel process 显示文摘 | Zhang Huangli Zhao Gaoyang | 2012 | Physica C2012,472,: | 1 |
| 4 | In vitro studies of polyethyleneimine coated miRNA microspheres as anticancer agents显示文摘RNA 作为一个基因沉默代理人起重要作用,为临床的处理的一个治疗学的代理人,并且在房间的区别,增长,和发展。然而, RNA 是很困难的工作与由于它的敏感和脆弱。在为基因交货 / 沉默使用 RNA 的另一个障碍是它的否定费用,它由房间膜引起它的排斥,它否定地也被控告。我们的最近的学习证明 miR-125b 是在 glioblastoma (GMB ) 的 upregulated 并且由支持房间增长并且禁止 apoptosis 在 GMB 房间起一个 oncogenic 作用。内长的 miR-125b 能被它的 antisense RNA 分子的 transfection 堵住, miR-125b antisense (miR-125b-AS ) 。因此,米尔 -- 125b-AS 能为癌症治疗作为一个基于 RNA 的代理人被开发。然而,不稳定性远这样在在进房间的交货的存储和困难期间限制了基于 RNA 的治疗的使用。在当前的工作,我们为断然控告的 RNA nanospheres (miR-125b-RNS 和 miR-125b-AS-RNS ) 的准备表明一种短、简单的一步舞技术与 bioavailable 聚合物涂, polyethylenimine (PEI ) 。这些 RNA nanospheres 能没有 liposomes 的使用,直接渗透房间。我们的学习证实进 nanospheres 的那变换 miR-125b 和 miR-125b-AS 是为存储 RNA 的一条可行途径。另外,这研究提供证据那 PEI 涂的 RNA nanospheres 有潜力被用作 anticancer 代理人的一个新奇的班。 | Irena Rytblat Ning Wu Huangli Xu Aharon Gedanken Xiukun Lin | 2016 | Nano Research2016,9,6: | 1 |
| 5 | Preparation of YBCO superconducting films by sol-gel process显示文摘 | Zhao Gaoyang Zhang Huangli Xue Renzhong | 2007 | Light Metals Aerospace Materials and Superconductors2007,,: | 1 |
| 6 | 显示文摘 | HUANGLi(黄丽) FANGBo(方波) ZHUYe(朱叶) etal | | ZhongguoXueyeLiubianxueZazhi0,,: | 1 |
| 7 | 显示文摘 | HUANGLi HONGJun LIUFan etal(黄丽 洪军 刘凡 等) | | 矿物学报0,,: | 1 |
| 8 | 显示文摘 | HUANGZong-ping HUANGLi LANGuang-lin etal(黄宗平 黄丽 蓝光琳 等) | 2012 | 分析试验室2012,31,2: | 1 |
| 9 | Preparation of the photosensitive copper complex and CuO film pattern显示文摘 | Zhang Huangli Zhao Gaoyang Xu Lanzhen | | 0,,: | 1 |
| 10 | Fabrication of YBCO film patterns and their properties显示文摘 | Zhao Gaoyang Zhang Huangli Chen Yuanqing | | 0,,12: | 1 |
| 11 | ImprovementoflocationmethodsbasedonRFID显示文摘 | WUL HUANGLY | 2013 | JChinaUnivPostsTelecom2013,20,1: | 1 |