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| 1 | Near-diffraction-limited linearly polarized narrow-linewidth random fiber laser with record kilowatt output显示文摘In this paper, we propose and experimentally investigate a linearly polarized narrow-linewidth random fiber laser(RFL) operating at 1080 nm and boost the output power to kilowatt level with near-diffraction-limited beam quality using a master oscillation power amplifier. The RFL based on a half-opened cavity, which is composed of a linearly polarized narrow-linewidth fiber Bragg grating and a 500 m piece of polarization-maintained Ge-doped fiber, generates a 0.71 W seed laser with an 88 pm full width at half-maximum(FWHM) linewidth and a 22.5 dB polarization extinction ratio(PER) for power scaling. A two-stage fiber amplifier enhances the seed laser to the maximal 1.01 k W with a PER value of 17 dB and a beam quality of M_x^2=1.15 and M_y^2=1.13. No stimulated Brillouin scattering effect is observed at the ultimate power level, and the FWHM linewidth of the amplified random laser broadens linearly as a function of the output power with a coefficient of about 0.1237 pm∕W.To the best of our knowledge, this is the first demonstration of a linearly polarized narrow-linewidth RFL with even kilowatt-level near-diffraction-limited output, and further performance scaling is ongoing. | JIANGMING XU LONG HUANG MAN JIANG JUN YE PENGFEI MA JINYONG LENG JIAN WU HANWEI ZHANG PU ZHOU | 2017 | Photonics Research2017，5，4： | 20 |
| 2 | All-fiberized and narrow-linewidth 5 kW power-level fiber amplifier based on a bidirectional pumping configuration显示文摘In this paper,an all-fiberized and narrow-linewidth 5 kW power-level fiber amplifier is presented.The laser is achieved based on the master oscillator power amplification configuration,in which the phase-modulated single-frequency laser is applied as the seed laser and a bidirectional pumping configuration is applied in the power amplifier.The stimulated Brillouin scattering,stimulated Raman scattering,and transverse mode instability effects are all effectively suppressed in the experiment.Consequently,the output power is scaled up to 4.92 kW with a slope efficiency of as high as approximately 80%.The 3-dB spectral width is about 0.59 nm,and the beam quality is measured to be M^(2)~1.22 at maximum output power.Furthermore,we have also conducted a detailed spectral analysis on the spectral width of the signal laser,which reveals that the spectral wing broadening phenomenon could lead to the obvious decrease of the spectral purity at certain output power.Overall,this work could provide a reference for obtaining and optimizing high-power narrow-linewidth fiber lasers. | Pengfei Ma Hu Xiao Wei Liu Hanwei Zhang Xiaolin Wang Jinyong Leng Pu Zhou | 2021 | High Power Laser Science and Engineering2021，9，3： | 9 |
| 3 | Revealing the dynamics of intensity fluctuation transfer in a random Raman fiber laser显示文摘Temporal intensity fluctuation is one of the inherent features of fiber lasers.When utilizing the fiber lasers to pump a random Raman fiber laser(RRFL),the intensity fluctuation transfer from the pump to the random lasing could affect the output performance significantly.In this paper,we comprehensively compared the spectral,temporal,and power characteristics of an RRFL pumped by two different fiber lasers—a temporally unstable fiber oscillator and a temporally stable amplified spontaneous emission(ASE)source.Owing to less impact of the intensity fluctuation transfer,the ASE source-pumped RRFL shows∼45.3%higher maximum output power,higher spectral purity(>99.9%)and optical signal-to-noise ratio(>40dB),weaker spectral broadening,and more stable temporal behavior compared to the fiber oscillator-pumped RRFL.Furthermore,based on the temporal-spatial-coupled Raman equations and the generalized nonlinear Schrödinger equations,we numerically revealed the impact of the pump intensity fluctuations on the output characteristics of RRFLs,and found that the temporal walk-off effect played an important role in the dynamics of intensity fluctuation transfer.This work may provide a reference for designing and implementing high-performance RRFLs and promote their practicability in sensing,telecommunications,and high-power applications. | Jun Ye Xiaoya Ma Yang Zhang Jiangming Xu Hanwei Zhang Tianfu Yao Jinyong Leng Pu Zhou | 2022 | Photonics Research2022，10，3： | 1 |
| 4 | Characterization of uncommon portosystemic collateral circulations inpatients with hepatic cirrhosis显示文摘 | Qin Wu Lijun Shen Jindong Chu Xuemei Ma Bo Jin Fanping Meng Jinpin Chen Yanling Wang Libing Wu Jun Han Wenhui Zhang Wei Ma Huaming Wang Hanwei Li | 2015 | Oncology Letters2015，，1： | 1 |
| 5 | Insights into the rheological modeling of semi-solid metals:Theoretical and simulation study显示文摘The power law model is the most widely used model for the rheological behavior of semi-solid metals(SSMs)in the numerical simulation of semi-solid processing.However,it is still not known why the anomalous negative flow exponent exists in the power law model for SSMs and its influence on the simulation.In this research,the rheological behavior of semi-solid Al-7Si-0.3Mg aluminum alloy is experimentally studied followed by modeling.The power law model fitting results show flow curves deviate from the experimental data and negative flow exponents,which are physically nonsensical and inapplicable to the simulation of SSMs flow proved by hydrodynamic analysis.This drawback of the power law model stems from neglecting the yield stress of SSMs.By contrast,the model referring Herschel-Bulkley(HB)theory which takes yield stress into consideration has reasonable flow exponent and yields good agreement between the fitting and experimental results.Furthermore,the simulation of die filling process is conducted,suggesting that the power law model over-optimistically predicts the tendency of blistering and misrun defects at low temperature and high filling velocity during semi-solid processing. | Zhen Ma Huarui Zhang Hanwei Fu Yanzhao Yang Jianji Wang Ming Du Hu Zhang | 2022 | Journal of Materials Science & Technology2022，，5： | 0 |
| 6 | lncRNA ELFN1-AS1 promotes proliferation,migration and invasion and suppresses apoptosis in colorectal cancer cells by enhancing G6PD activity显示文摘Tumour cells change their metabolic patterns to support high proliferation rates and cope with oxidative stress.The lncRNA ELFN1-AS1 is highly expressed in a wide range of cancers and is essential to the proliferation and apoptosis of tumour cells.Nevertheless,its function in the metabolic reprogramming of tumour cells is unclear.Here we show that ELFN1-AS1 promotes glucose consumption as well as lactate and NADPH production.Database searching,bioinformatics analysis,RNA immunoprecipitation(RIP)and RNA pull-down assays show that ELFN1-AS1 enhances glucose-6-phosphate dehydrogenase(G6PD)expression and activates the pentose phosphate pathway(PPP)by promoting TP53 degradation.In addition,luciferase reporter assay and chromatin immunoprecipitation(ChIP)show that YY1 binds to the ELFN1-AS1 promoter to promote transcriptional activation of ELFN1-AS1.Consistent with the in vitro experiments,knockdown of ELFN1-AS1 impedes the growth of tumours transplanted into mice by inhibiting the expression of G6PD.In conclusion,this study reveals that ELFN1-AS1 activates the PPP,and validates the regulatory role of the YY1/ELFN1-AS1/TP53/G6PD axis in colorectal cancer. | Fahong Wu Wei Zhang Hangzhi Wei Hanwei Ma Guangxian Leng Youcheng Zhang | 2023 | Acta Biochimica et Biophysica Sinica2023，55，4： | 0 |
| 7 | Phosphorylation of the LCB1 subunit of Arabidopsis serine palmitoyltransferase stimulates its activity and modulates sphingolipid biosynthesis显示文摘Sphingolipids are the structural components of membrane lipid bilayers and act as signaling molecules in many cellular processes.Serine palmitoyltransferase(SPT)is the first committed and rate-limiting enzyme in the de novo sphingolipids biosynthetic pathway.The core SPT enzyme is a heterodimer consisting of LONG-CHAIN BASE1(LCB1)and LCB2 subunits.SPT activity is inhibited by orosomucoid proteins and stimulated by small subunits of SPT(ssSPTs).However,whether LCB1 is modified and how such modification might regulate SPT activity have to date been unclear.Here,we show that activation of MITOGEN-ACTIVATED PROTEIN KINASE 3(MPK3)and MPK6 by upstream MKK9 and treatment with Flg22(a pathogen-associated molecular pattern)increases SPT activity and induces the accumulation of sphingosine long-chain base t18:0 in Arabidopsis thaliana,with activated MPK3and MPK6 phosphorylating AtLCB1.Phosphorylation of AtLCB1 strengthened its binding with AtLCB2b,promoted its binding with ssSPTs,and stimulated the formation of higher order oligomeric and active SPT complexes.Our findings therefore suggest a novel regulatory mechanism for SPT activity. | Yuan Li Hanwei Cao Tingting Dong Xiaoke Wang Liang Ma Kun Li Huiqiang Lou Chun-Peng Song Dongtao Ren | 2023 | Journal of Integrative Plant Biology2023，65，6： | 0 |
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