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| 1 | Human papillomavirus DNA and P16~(INK4A) expression in concurrent esophageal and gastric cardia cancers显示文摘AIM:To investigate the relationship between human papillomavirus (HPV) infection and concurrent esophagus and gastric cardia cancer from the same patient (CC) and examine the significance of P16 INK4A protein expression.METHODS:Polymerase chain reaction was used to detect the presence of HPV type16 (HPV16).The expression of P16 INK4A protein was detected using immunohistochemistry.RESULTS:Among the CC specimens,HPV16-DNA was found in eight cases of esophageal squamous cell carcinoma (ESCC) and five cases of gastric cardia adenocarcinoma (GCA),respectively (47% vs 29%),and two of both ESCC and GCA.P16 INK4A was highly expressed in both ESCC and GCA.In the HPV-associated positive CC,higher P16 INK4A expression was observed in the GCA than in the ESCC (75% vs 25%,P < 0.05).CONCLUSION:HPV16 as a correlated risk factor may play an important role in the development of ESCC and GCA.P16 INK4A may be a screening index in the HPVassociated carcinoma of gastric cardia. | Guang-Cheng Ding,Tao Guo,Department of Gastroenterology,The First Affiliated Hospital and The Fifth Affiliated Hospital,Zhengzhou University,Zhengzhou 450052,Henan Province,China Jing-Li Ren,Xin Song,Sheng-Li Zhou,Zong-Min Fan,LiDong Wang,Henan Key Laboratory for Esophageal Cancer Research,Department of Gastroenterology,The First Affiliated Hospital,College of Basic Medicine,Zhengzhou University,Zhengzhou 450052,Henan Province,China Fu-Bao Chang,Department of Thoracic Surgery,Linzhou Center Hospital,Linzhou 456500,Henan Province,China Ji-Lin Li,Department of Pathology,Yaocun Esophageal Cancer Hospital,Linzhou 456500,Henan Province,China Ling Yuan,Department of Oncoradiotherapy,Henan Province Tumor Hospital,Zhengzhou 450003,Henan Province,China Yi Zeng,Institute of Virology,Chinese Academy of Preventive Medicine,Beijing 100052,China | 2010 | World Journal of Gastroenterology2010，16，46： | 11 |
| 2 | TEM Study on the Formation Process of TiO_2 Nanotubes显示文摘The process, that the polycrystalline TiO2 powders were converted into TiO2 nanotubes, was observed with transmission electron microscope. The results obtained indicated that in concentrated NaOH aqueous solution, anisotropic swelling appears on the polycrystalline TiO2 granula at first, and then the nanotubes are formed. | Jing Wei ZHANG, Xin Yong GUO, Zhen Sheng JIN*, Shun Li ZHANG, Jing Fang ZHOU, Zhi Jun ZHANG* Lab of Special Functional Materials, Henan University, Kaifeng 475001 | 2003 | Chinese Chemical Letters2003，14，4： | 7 |
| 3 | CONCEPT, DISTRIBUTION LAW AND FORMATION MACHANISM OF INLAND SALINE ALKALINE WETLAND─ ─ Taking Songliao Plain for Example显示文摘The paper, taking Songliao Plain for example, studied the concept, distribution law and formation mechanism of inland saline alkaline wetland. The inland saline alkaline wetland is distributed over the inland region of arid or semi arid climate; it is the wet or slightly stagnant environment, forming saline alkaline soil and salt vegetation and making the geogra phical environment fonming complex with an ecosystem of saline alkaline wetland. The laws of zone nature and non zone nature control the distribution of the inland saline alkaline wetland that extensively spreads in north part of China and other countries. The inland saline alkaline wetland is formed jointly by atmosphere, hydrosphere, lithosphere and biosphere including intellectual sphere. Under the special condition, the artificial activity is possibly the key function. In order to improve the human environment, it is a great duty confronting the whole world to rationally transform the inland saline alkaline wetland. Therefore, we presented an anti inland theory to promote the environment transformation. | SUN Guang you1, LUO Xin zheng2 , YI Fu ke1 , ZHANG Xiao ping1 (1.Changchun Institute of Geography, the Chinese Academy of Sciences,Changchun 130021,P.R.China 2.Institute of Geography, Academy of Henan Province, Zhengzhou 450052,P.R.China) | 2000 | Chinese Geographical Science2000，10，3： | 5 |
| 4 | A Novel Green Preparation ofα,α′-Bis(substituted benzylidene)-cycloalkanones Promoted by FeCl3·6H2O in Ionic Liquid显示文摘α, α'-Bis(substituted benzylidene)cycloalkanones were efficiently prepared fromcycloalkanones and benzaldehydes in [bmim][BF4] by using iron(Ⅲ) chloride hexahydrate as acatalyst. It is shown that [bmim][BF4] and iron(Ⅲ) chloride hexahydrate can be quantitativelyrecovered and be reused effectively for many times. Compared with the known methods, thisnovel process has the advantage of being an environmentally benign process together with goodyields and mild reaction conditions. | Xin Ying ZHANG, Xue Sen FAN, Hong Ying NIU, Jian Ji WANGSchool of Chemical and Environmental Sciences, Henan Normal University, Key Laboratory ofEnvironmental Science and Engineering of Henan Education Department,Xinxiang 453002 | 2003 | Chinese Chemical Letters2003，14，10： | 5 |
| 5 | Testing of tuberculosis infection among Chinese adolescents born after terminating the Bacillus Calmette-Guerin booster vaccination: subgroup analysis of a population-based cross-sectional study显示文摘 | Hengjing Li Henan Xin Shukun Qian Xiangwei Li Haoran Zhang Mufei Li Boxuan Feng Qi Jin Lei Gao | 2017 | Frontiers of Medicine2017，11，4： | 5 |
| 6 | Isolation and characterization of emerging subgroup J avian leukosis virus associated with hemangioma in egg-type chickens显示文摘 | Hanzhang Lai Henan Zhang Zhangyong Ning Ruiai Chen Wenyan Zhang Aijian Qing Chaoan Xin Kangzhen Yu Weisheng Cao Ming Liao | 2011 | Veterinary Microbiology2011，，3： | 3 |
| 7 | A Mild Oxidant for the Regeneration of Carbonyl Compounds from Oximes in Nonaqueous Condition显示文摘Dioxane-NO2 was employed to oxidize oximes to corresponding aldehydes and ketones in high yield in nonaqueous condition at room temperature. The reaction proved to be mild and selective. | Qing Zhi ZHANG*, Shen Song ZHANG, Xin Ming LIU, Jin Ming ZHANG College of Chemistry and Environmental Science, Henan Normal University, Xinxiang 453002 | 2001 | Chinese Chemical Letters2001，12，2： | 1 |
| 8 | Studies on the Absorption of NO_2 by Polyethylene Glycol and the Oxidizing Properties of the Resulting Absorbent Product显示文摘PEG (Polyethylene glycol average molecular weight 300) is used as absorbent of NO2. The absorption efficiency is found to reach up to 97%. The absorbing product, PEG NO2, can be used to cleave benzyl ethers mildly and selectively to benzaldehyde and corresponding fatty alcohols, showing that PEG is a valuable oxidizing agent of benzyl ethers. As a carrier of NO2.PEG can be recovered and utilized repeatedly after the oxidation. | Xue Sen FAN Qing Zhi ZHANG Xin Ying ZRANG Sen Song ZHANG (Department of Chemistry, Henan Normal University, Xinxiang, 453002) | 1997 | Chinese Chemical Letters1997，8，9： | 0 |
| 9 | A Novel Unsupervised MRI Synthetic CT Image Generation Framework with Registration Network显示文摘In recent years,radiotherapy based only on Magnetic Resonance(MR)images has become a hot spot for radiotherapy planning research in the current medical field.However,functional computed tomography(CT)is still needed for dose calculation in the clinic.Recent deep-learning approaches to synthesized CT images from MR images have raised much research interest,making radiotherapy based only on MR images possible.In this paper,we proposed a novel unsupervised image synthesis framework with registration networks.This paper aims to enforce the constraints between the reconstructed image and the input image by registering the reconstructed image with the input image and registering the cycle-consistent image with the input image.Furthermore,this paper added ConvNeXt blocks to the network and used large kernel convolutional layers to improve the network’s ability to extract features.This research used the collected head and neck data of 180 patients with nasopharyngeal carcinoma to experiment and evaluate the training model with four evaluation metrics.At the same time,this research made a quantitative comparison of several commonly used model frameworks.We evaluate the model performance in four evaluation metrics which achieve Mean Absolute Error(MAE),Root Mean Square Error(RMSE),Peak Signal-to-Noise Ratio(PSNR),and Structural Similarity(SSIM)are 18.55±1.44,86.91±4.31,33.45±0.74 and 0.960±0.005,respectively.Compared with other methods,MAE decreased by 2.17,RMSE decreased by 7.82,PSNR increased by 0.76,and SSIM increased by 0.011.The results show that the model proposed in this paper outperforms other methods in the quality of image synthesis.The work in this paper is of guiding significance to the study of MR-only radiotherapy planning. | Liwei Deng Henan Sun Jing Wang Sijuan Huang Xin Yang | 2023 | Computers, Materials & Continua2023，77，11： | 0 |
| 10 | Synthesis of Macrocyclic Arsinous Acid Esters显示文摘The reactions of the his (dimethylamino) alkylarsine with dids lead to the formations ofmacrocyclic arsinous acid esters. The synthesis of title compounds was described and theirslructures were characterized by elemental analysis, IR, 1HNMR, and MS. | Xin You CHENI Ying Qin YANG Wen Tian TAO(1’Department of Chemistry, Xiaogan Teachers College, Hubei 432100)(2Department of Chemistry, Xinyang Teachers College, Henan 464000)(3Department of Chemistry, Wuhan University, Wuhan 430072) | 1999 | Chinese Chemical Letters1999，10，12： | 0 |
| 11 | Ultrasonic investigations on elastic properties of (Bi,Pb)-Sr-Ca-Cu oxide ceramic superconductors显示文摘Ultrasonic velocities have been measured in single phaseBi1.7Pb0.3Sr2 CaCu2O8+x and Bi1.7Pb0.3Sr2Ca2O10+x polycrystalline samples.Anomalous changes of both longitudinal and transverse velocities wereobserved near 200K,which indicates that some structural phase transitiomight occur.The elastic constants of these samples have been determinedfrom the measured ultrasonic velocity data,which are much smaller thanthose of YBa2Cu3O7-yand BaTiO3,manifesting that the interlayer coup-ling will dramatically decrease when the c-axes of the unit cells of theseperovstite-like multilayer ceramics increase.The values of Poisson ratio,however,of those ceramics are very close,implying similar interatomicbonding forces.Corrected to void-free state,the Debye temperature ofthese materials is estirnated as 270±20k.The temperature dependence ofDebye temperatures for these materials is also calculated by using thesame method and reported for the first time. | HE Yusheng XIANG Jiong WANG Xin(Department of Physics, Tsinghua University)ZHANG Jincang CHANG Fanggao(Department of Physics, Henan Normal University)HE Aisheng(Physics Division, North University of Technology) | 1990 | Chinese Journal of Acoustics1990，9，3： | 0 |
| 12 | Selective hydrolysis of lignocelluloses from corn stalk in an ionic liquid显示文摘Although lots of basic studies , such as the hydrolysis and dissolution of lignocelluloses has made great progress in recent years , the hydrolysates containing complex mixture of pentose and hexose are very hard to be separated , and these process sometimes cause serious environmental problems in practical application of cellulose polymer degradation science.Herein , an efficient two-stage method for selective hydrolysis of lignocelluloses biomass is being developed in this paper by controlling of pH in an ionic liquid.The lignin-hemicelluloses matrix in corn stalk was hydrolyzed into xylose in 23.1% yield in the first stage ; and cellulose-rich residues from the first stage was by farther hydrolyzed to provide a glucose in 26.9%yield.Structure of the products were identified by 13 C NMR.It should be mentioned that , the ionic liquid which can be regenerated and reused throughout the process. The present work significantly opens an a new path to utilize each component of lignocellulose as raw materials producing biofuels , renewable energy and fine chemicals. | YIN WeiPing 1 , 2 , LI Xin 1 , REN YunLai 1 , ZHAO Shuang 1 , 2 , WANG JianJi 1 , 2 ( 1 School of Chemical Engineering and Pharmaceutics , Henan University of Science and Technology , Luoyang 471003 , Henan , China 2 The key laboratory for biomass clean energy , Henan University of Science and Technology , Luoyang 471003 , Henan , China ) | 2012 | 化工进展2012，31，S1： | 0 |
| 13 | Diversity and independent evolutionary profiling of rodent-borne viruses in Hainan,a tropical island of China显示文摘The risk of emerging infectious diseases(EID)is increasing globally.More than 60%of EIDs worldwide are caused by animal-borne pathogens.This study aimed to characterize the virome,analyze the phylogenetic evolution,and determine the diversity of rodent-borne viruses in Hainan Province,China.We collected 682 anal and throat samples from rodents,combined them into 28 pools according to their species and location,and processed them for next-generation sequencing and bioinformatics analysis.The diverse viral contigs closely related to mammals were assigned to 22 viral families.Molecular clues of the important rodent-borne viruses were further identified by polymerase chain reaction for phylogenetic analysis and annotation of genetic characteristics such as arenavirus,coronavirus,astrovirus,pestivirus,parvovirus,and papillomavirus.We identified pestivirus and bocavirus in Leopoldoms edwardsi from Huangjinjiaoling,and bocavirus in Rattus andamanensis from the national nature reserves of Bangxi with low amino acid identity to known pathogens are proposed as the novel species,and their rodent hosts have not been previously reported to carry these viruses.These results expand our knowledge of viral classification and host range and suggest that there are highly diverse,undiscovered viruses that have evolved independently in their unique wildlife hosts in inaccessible areas. | Youyou Li Chuanning Tang Yun Zhang Zihan Li Gaoyu Wang Ruoyan Peng Yi Huang Xiaoyuan Hu Henan Xin Boxuan Feng Xuefang Cao Yongpeng He Tonglei Guo Yijun He Haoxiang Su Xiuji Cui Lina Niu Zhiqiang Wu Jian Yang Fan Yang Gang Lu Lei Gao Qi Jin Meifang Xiao Feifei Yin Jiang Du | 2023 | Virologica Sinica2023，38，5： | 0 |
| 14 | 不同模具结构模仁尺寸对模仁变形的影响显示文摘利用有限元方法,以方形塑件为例,同时考虑温度场和压力场等因素,对不同模具结构的模仁进行了变形分析。并考虑刚度和成本因素,优化了成型该塑件的模仁结构尺寸。结果表明,相同条件下,该塑件三板模模仁变形比两板模小,模仁宽度对两种模具结构的模仁变形的影响都较大,下模仁高度对下模仁变形影响较大,而上模仁高度对上模仁变形的影响较小。 | WANG Xin FAN Jiuhong Mechanical Engineering College,Henan Engineering College Department of Intelligent Engineering,Henan Mechanical and Electrical Career College | 2016 | 中国塑料2016，30，9： | 0 |
| 15 | Study on the Unequal Weight Moving Average Predition Model Based on the Neur | TAO Youde YANG Hongzhi(Xin Yang Teachers Collere,HeNan 464000) | 1995 | Systems Science and Systems Engineering1995，5，3： | 0 |
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