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| 1 | Risk factors for small bowel angioectasia:The impact of visceral fat accumulation显示文摘AIM: To investigate visceral fat accumulation in association with the risk of small bowel angioectasia.METHODS: We retrospectively investigated 198 consecutive patients who underwent both capsule endoscopy and CT for investigation of obscure gastrointestinal bleeding(OGIB) from January 2009 to September 2013. The visceral fat area(VFA) and subcutaneous fat area were measured by CT, and information on comorbidities, body mass index, and medications was obtained from their medical records.Logistic regression analysis was used to evaluate associations.RESULTS: Capsule endoscopy revealed small bowel angioectasia in 18/198(9.1%) patients with OGIB.Compared to patients without small bowel angioectasia,those with small bowel angioectasia had a significantly higher VFA(96 ± 76.0 cm2 vs 63.4 ±51.5 cm2, P = 0.016) and a higher prevalence of liver cirrhosis(61% vs 22%, P < 0.001). The proportion of patients with chronic renal failure was higher in patients with small bowel angioectasia(22% vs 9%,P = 0.11). There were no significant differences in subcutaneous fat area or waist circumference. The prevalence of small bowel angioectasia progressively increased according to the VFA. Multivariate analysis showed that the VFA [odd ratio(OR) for each 10-cm2 increment = 1.1; [95% confidence interval(CI):1.02-1.19; P = 0.021] and liver cirrhosis(OR = 6.1,95%CI: 2.2-18.5; P < 0.001) were significant risk factors for small bowel angioectasia.CONCLUSION: VFA is positively associated with theprevalence of small bowel angioectasia, for which VFA and liver cirrhosis are independent risk factors in patients with OGIB. | Atsuo Yamada Ryota Niikura Yuka Kobayashi Hirobumi Suzuki Shuntaro Yoshida Hirotsugu Watabe Yutaka Yamaji Yoshihiro Hirata Kazuhiko Koike | 2015 | World Journal of Gastroenterology2015，21，23： | 4 |
| 2 | Impact of fecal occult blood on obscure gastrointestinal bleeding:Observational study显示文摘AIM: To elucidate the association between small bowel diseases(SBDs) and positive fecal occult blood test(FOBT) in patients with obscure gastrointestinal bleeding(OGIB).METHODS: Between February 2008 and August 2013, 202 patients with OGIB who performed both capsule endoscopy(CE) and FOBT were enrolled(mean age; 63.6 ± 14.0 years, 118 males, 96 previous overt bleeding, 106 with occult bleeding). All patients underwent immunochemical FOBTs twice prior to CE. Three experienced endoscopists independently reviewed CE videos. All reviews and consensus meeting were conducted without any information on FOBT results. The prevalence of SBDs was compared between patients with positive and negative FOBT.RESULTS: CE revealed SBDs in 72 patients(36%). FOBT was positive in 100 patients(50%) and negative in 102(50%). The prevalence of SBDs was significantly higher in patients with positive FOBT than those with negative FOBT(46% vs 25%, P = 0.002). In particular, among patients with occult OGIB, the prevalence of SBDs was higher in positive FOBT group than negative FOBT group(45% vs 18%, P = 0.002). On the other hand, among patients with previous overt OGIB, there was no significant difference in the prevalence of SBDs between positive and negative FOBT group(47% vs 33%, P = 0.18). In disease specific analysis among patients with occult OGIB, the prevalence of ulcer and tumor were higher in positive FOBT group than negative FOBT group. In multivariate analysis, only positive FOBT was a predictive factors of SBDs in patients with OGIB(OR = 2.5, 95%CI: 1.4-4.6, P = 0.003). Furthermore, the trend was evidentam on g patients with occult OGIB who underwent FOBT on the same day or a day before CE. The prevalence of SBDs in positive vs negative FOBT group were 54% vs 13% in patients with occult OGIB who underwent FOBT on the same day or the day before CE(P = 0.001), while there was no significant difference between positive and negative FOBT group in those who underwent FOBT two or more days before CE(43% vs 25%, P = 0.20).CONCLUSION: The present study suggests that positive FOBT may be useful for predicting SBDs in patients with occult OGIB. Positive FOBT indicates higher likelihood of ulcers or tumors in patients with occult OGIB. Undergoing CE within a day after FOBT achieved a higher diagnostic yield for patients with occult OGIB. | Yuka Kobayashi Hirotsugu Watabe Atsuo Yamada Hirobumi Suzuki Yoshihiro Hirata Yutaka Yamaji Haruhiko Yoshida Kazuhiko Koike | 2015 | World Journal of Gastroenterology2015，21，1： | 2 |
| 3 | Immunomodulatory Effects of Granulocyte and Monocyte Adsorption Apheresis as a Treatment for Patients with Ulcerative Colitis显示文摘 | Nobuhito Kashiwagi Kazuhito Sugimura Hirobumi Koiwai Hironori Yamamoto Toshikazu Yoshikawa Abby R. Saniabadi Masakazu Adachi Takashi Shimoyama | 2002 | Digestive Diseases and Sciences2002，，： | 1 |
| 4 | Cell cycle-dependent and ATM-independent expression of human Chkl kinase 显示文摘 | Yokos K Nobumoto W Hirobumi M | 1999 | Oncogene1999，18，： | 1 |
| 5 | Mitochondrial DNA Sequence-Based Population Genetic Structure of the Firefly, Pyrocoelia rufa (Coleoptera: Lampyridae)显示文摘 | Sang-Chul Lee Jin-Sik Bae Iksoo Kim Hirobumi Suzuki Seong-Ryul Kim Jong-Gill Kim Keun-Young Kim Won-Jin Yang Sang-Mong Lee Hung-Dae Sohn Byung-Rae Jin | 2003 | Biochemical Genetics (-)2003，，11： | 1 |
| 6 | Estimation of single event transient voltage pulses in VLSI circuits from heavy-ion-induced transient currents measured in a single MOSFET显示文摘 | DAISUKE K HIROBUMI S KAZUYUKI H | 2007 | IEEE Transactions on Nuclear Science2007，54，4： | 1 |
| 7 | Ultrathin endoscopy versus high-resolution endoscopy for diagnosing superficial gastric neoplasia显示文摘 | Hirobumi Toyoizumi Mitsuru Kaise Hiroshi Arakawa Jin Yonezawa Yukinaga Yoshida Masayuki Kato Noboru Yoshimura Ken-ichi Goda Hisao Tajiri | 2009 | Gastrointestinal Endoscopy2009，，2： | 1 |
| 8 | Phylogeographic Analysis of the Firefly, Luciola lateralis, in Japan and Korea Based on Mitochondrial Cytochrome Oxidase II Gene Sequences (Coleoptera: Lampyridae)显示文摘 | Hirobumi Suzuki Yasushi Sato Nobuyoshi Ohba Jin-Sik Bae Byung-Rae Jin Hung-Dae Sohn Sam-Eun Kim | 2004 | Biochemical Genetics (-)2004，，9： | 1 |
| 9 | Mitochondrial DNA Sequence-Based Population Genetic Structure of the Firefly, Pyrocoelia rufa (Coleoptera: Lampyridae)显示文摘 | Sang-Chul Lee Jin-Sik Bae Iksoo Kim Hirobumi Suzuki Seong-Ryul Kim Jong-Gill Kim Keun-Young Kim Won-Jin Yang Sang-Mong Lee Hung-Dae Sohn Byung-Rae Jin | 2003 | Biochemical Genetics (-)2003，，11： | 1 |
| 10 | Simultaneous intermetallics suppression and residual-stress relaxation of heat-resistant Nb-interlayer-inserted Ti-6Al-4V/Si_(3)N_(4)joints via one-step transient liquid phase bonding and brazing显示文摘This work has successfully proposed a solution to produce robust Nb-interlayer-inserted Ti-6Al-4V/Si_(3)N_(4)joints optimized for a maximum operating temperature of 873 K;transient liquid phase bonding(TLPB)of Ti-6Al-4V/Nb side was carried out with Cu and Ni fillers to suppress brittle intermetallic compounds(IMCs),whereas brazing of Nb/Si_(3)N_(4)side was performed using a highly ductile Ti-added Ag-rich filler for effective residual-stress relaxation.A sound yet simple one-step bonding process incorporating simul-taneous TLPB and brazing was achieved with a relatively short holding time of 10 min at 1213 K.TLPB of Ti-6Al-4V/Nb side with Cu and Ni foils of 2-μm-thick each as a laminated filler suppressed brittle Ti-based IMCs and developed a homogenized microstructure consisting mainly of(α+β)-Ti via isothermal solidification.Meanwhile,brazing of Nb/Si_(3)N_(4)side with 100-μm-thick SILVER-ABA filler(92.75Ag-5Cu-1Al-1.25Ti mass%)foil enhanced interfacial bonding with sufficient total Ti content and accommodated residual stress better than conventional eutectic Ag-Cu-based fillers,and it was verified by finite element analysis with consideration of materials’temperature-dependent elasto-plastic properties.All joints with a bonding area of 10 mm×10 mm were tested via symmetrical four-point bending from room temper-ature(RT)to 873 K fractured from Nb/Si_(3)N_(4)side.When re-heating the joints from RT to 673 K,frac-ture initiation gradually shifted from Si_(3)N_(4)towards interfacial-compounds/Si_(3)N_(4)interface and bending strengths maintained∼220 MPa as weakening of SILVER-ABA filler was compensated by residual-stress relaxation in Si_(3)N_(4).When tested at 873 K,joints fractured mainly across the Ag-rich solid solution in a ductile manner and bending strength degraded by∼20%to 171 MPa as weakening of SILVER-ABA filler dominated. | Fei Shen Ong Hirobumi Tobe Eiichi Sato | 2023 | Journal of Materials Science & Technology2023，，8： | 1 |
| 11 | Biochemical systematics of Japanese fireflies of the subfamily Luciolinae and their flash communication systems显示文摘 | Hirobumi Suzuki Yasushi Sato Shizuo Fujiyama Nobuyoshi Ohba | 1996 | Biochemical Genetics (-)1996，，5： | 1 |
| 12 | Acute interstitial nephritis associated with ulcerative colitis显示文摘 | Hirobumi Tokuyama Shu Wakino Konosuke Konishi Akinori Hashiguchi Koichi Hayashi Hiroshi Itoh | 2010 | Clinical and Experimental Nephrology2010，，5： | 1 |
| 13 | Sentinel Node Detection Method Using Contrast-Enhanced Ultrasonography with Sonazoid in Breast Cancer: Preliminary Clinical Study显示文摘 | Kiyoka Omoto Hiroaki Matsunaga Natsuki Take Yasuo Hozumi Megumi Takehara Yawara Omoto Mikio Shiozawa Hirobumi Mizunuma Hiroki Harashima Nobuyuki Taniguchi Mikihiko Kawano | 2009 | Ultrasound in Medicine & Biology2009，，8： | 1 |
| 14 | Callosal bleeding in a case of Marchiafava-Bignami disease显示文摘 | Mutsuo Kamaki Mitsuru Kawamura Hirobumi Moriya | 1996 | Journal of the Neurological Sciences1996，136，： | 1 |
| 15 | Development of High Ratio Coke Mixed Charging Technique to the Blast Furnace显示文摘 | Shiro Watakabe Kanji Takeda Hirobumi Nisinmra | 2006 | ISIJ International2006，46，4： | 1 |
| 16 | Preparation of highly dispersed core-shell-type titania nanocapsules containing a single Ag nanoparticle显示文摘 | Hideki Sakai Takashi Kanda Hirobumi Shibata | 2006 | The Journal of the American Chemical Society2006，128，15： | 1 |
| 17 | Ultrathin endoscopy versus high-resolution endoscopy for diagnosing superficial gastric neoplasia显示文摘 | Hirobumi Toyoizumi Mitsuru Kaise Hiroshi Arakawa Jin Yonezawa Yukinaga Yoshida Masayuki Kato Noboru Yoshimura Ken-ichi Goda Hisao Tajiri | 2009 | Gastrointestinal Endoscopy2009，，2： | 1 |
| 18 | Shape Memory Behavior of [111]-Oriented NiTi Single Crystals After Stress-Assisted Aging显示文摘The shape memory behavior of [111]-oriented Ni_(51)Ti_(49) (at.%) single crystals was investigated after stressassisted aging at 500 °C for 1.5 h under a compressive stress of-150 MPa.It was found that a single family of Ni_4Ti_3 precipitates with two crystallographically equivalent variants was formed after aging under compressive stress.Stressassisted aging resulted in tensile two-way shape memory effect strain of 1.56% under-5 MPa.Thermal cycling under-600 MPa resulted in a transformation strain of-2.15%,while the subsequent thermal cycling under-5 MPa resulted in a tensile two-way shape memory effect strain of 2.2%. | Irfan Kaya Hirobumi Tobe Haluk Ersin Karaca Emre Acar Yuriy Chumlyakov | 2016 | Acta Metallurgica Sinica(English Letters)2016，29，3： | 1 |
| 19 | Study on metal-base self-lubricating composites containing tungsten disulfide 显示文摘 | Tsuya Yuko Shimura Hirobumi Matsunaga Masahisa | 1973 | Lubrication Engineering1973，29，11： | 1 |
| 20 | Immunomodulatory Effects of Granulocyte and Monocyte Adsorption Apheresis as a Treatment for Patients with Ulcerative Colitis显示文摘 | Nobuhito Kashiwagi Kazuhito Sugimura Hirobumi Koiwai Hironori Yamamoto Toshikazu Yoshikawa Abby R. Saniabadi Masakazu Adachi Takashi Shimoyama | 2002 | Digestive Diseases and Sciences2002，，6： | 1 |
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