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| 1 | Development, chromosome location and genetic mapping of EST-SSR markers in wheat显示文摘A number of 151695 wheat expression sequence tags (ESTs) that originated from GenBank/dbEST from July 14, 2003 to August 24, 2004 were used to search for simple sequence repeats (SSRs) with motif 2―5 bp, and 2038 simple sequence repeats (EST-SSRs), which accounted for 1.34% of EST database, were identified. Based on these SSR sequences, 249 EST-SSR primer pairs and 166 amplified clear bands in various wheat cultivars were designed. These EST-SSR markers can be used as new molecular markers in wheat and related species. Using Chinese Spring nulli-tetrasomic lines, 93 EST-SSR primer pairs and 193 EST-SSR loci were located on 19 wheat chromosomes except for 4A and 4B. Forty-three loci were mapped on 11 chromosomes of the genetic frame- work map previously constructed using recombinant inbred lines. | CHEN Haimei LI Linzhi WEI Xianyun LI Sishen LEI Tiandong HU Haizhou WANG Honggang ZHANG Xiansheng | 2005 | Chinese Science Bulletin2005，50，20： | 48 |
| 2 | A simple model of radial nerve injury in the rhesus monkey to evaluate peripheral nerve repair显示文摘Current research on bone marrow stem cell transplantation and autologous or xenogenic nerve transplantation for peripheral nerve regeneration has mainly focused on the repair of peripheral nerve defects in rodents.In this study,we established a standardized experimental model of radial nerve defects in primates and evaluated the effect of repair on peripheral nerve injury.We repaired 2.5-cm lesions in the radial nerve of rhesus monkeys by transplantation of autografts,acellular allografts,or acellular allografts seeded with autologous bone marrow stem cells.Five months after surgery,regenerated nerve tissue was assessed for function,electrophysiology,and histomorphometry.Postoperative functional recovery was evaluated by the wrist-extension test.Compared with the simple autografts,the acellular allografts and allografts seeded with bone marrow stem cells facilitated remarkable recovery of the wrist-extension functions in the rhesus monkeys.This functional improvement was coupled with radial nerve distal axon growth,a higher percentage of neuron survival,increased nerve fiber density and diameter,increased myelin sheath thickness,and increased nerve conduction velocities and peak amplitudes of compound motor action potentials.Furthermore,the quality of nerve regeneration in the bone marrow stem cells-laden allografts group was comparable to that achieved with autografts.The wrist-extension test is a simple behavioral method for objective quantification of peripheral nerve regeneration. | Dong Wang Xijun Huang Guo Fu Liqiang Gu Xiaolin Liu Honggang Wang Jun Hu Jianhua Yi Xiaofeng Niu Qingtang Zhu | 2014 | Neural Regeneration Research2014，9，10： | 3 |
| 3 | Comparison of dimension reduction-based logistic regression models for case-control genome-wide association study:principal components analysis vs.partial least squares显示文摘With recent advances in biotechnology, genome-wide association study(GWAS) has been widely used to identify genetic variants that underlie human complex diseases and traits. In case-control GWAS, typical statistical strategy is traditional logistical regression(LR) based on single-locus analysis. However, such a single-locus analysis leads to the well-known multiplicity problem, with a risk of inflating type I error and reducing power. Dimension reduction-based techniques, such as principal component-based logistic regression(PC-LR), partial least squares-based logistic regression(PLS-LR), have recently gained much attention in the analysis of high dimensional genomic data. However, the perfor?mance of these methods is still not clear, especially in GWAS. We conducted simulations and real data application to compare the type I error and power of PC-LR, PLS-LR and LR applicable to GWAS within a defined single nucleotide polymorphism(SNP) set region. We found that PC-LR and PLS can reasonably control type I error under null hypothesis.On contrast, LR, which is corrected by Bonferroni method, was more conserved in all simulation settings. In particular, we found that PC-LR and PLS-LR had comparable power and they both outperformed LR, especially when the causal SNP was in high linkage disequilibrium with genotyped ones and with a small effective size in simulation. Based on SNP set analysis, we applied all three methods to analyze non-small cell lung cancer GWAS data. | Honggang Yi Hongmei Wo Yang Zhao Ruyang Zhang Junchen Dai Guangfu Jin Hongxia Ma Tangchun Wu Zhibin Hu Dongxin Lin Hongbing Shen Feng Chen | 2015 | The Journal of Biomedical Research2015，29，4： | 2 |
| 4 | Numerical simulation on flow, combustion and heat transfer of ethylene cracking furnaces显示文摘 | Hu Guihua Wang Honggang Qian Feng | 2010 | Chemical Engineering Science2010，，8： | 2 |
| 5 | First identification of xanthone sulfonamides as potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors显示文摘 | Hu HongGang Liao HongLi Zhang Jun | 2010 | Bioorg Med Chem Lett2010，20，10： | 1 |
| 6 | Synthesis and in vitr o inhibitory activity of matrine derivatives towards pro - inflammatory cytokin es显示文摘 | Honggang Hu Shaozhan Wang Chunmei Zhang | 2010 | Bioorganic & Medicinal Chemistry Letters2010，20，24： | 1 |
| 7 | Insulin-like growth factor 1 improves the efficacy of mesenchymal stem cells transplantation in a rat model of myocardial infarction显示文摘 | Jun Guo Guosheng Lin Cuiyu Bao Zhimin Hu Honggang Chu Mingyan Hu | 2008 | Journal of Biomedical Science2008，，1： | 1 |
| 8 | Generalized cryptanalysis of RSA with small public exponent显示文摘In this paper, we demonstrate that there exist weak keys in the RSA public-key cryptosystem with the public exponent e = N~α N^(0.5). In 1999, Boneh and Durfee showed that when α≈ 1 and the private exponent d = N~β< N^(0.292), the system is insecure. Moreover, their attack is still effective for 0.5 < α < 1.875.We propose a generalized cryptanalytic method to attack the RSA cryptosystem with α≤0.5. For c = [(1-α)/α] and e^(γc)≡ d(mod e^c), when γ, β satisfy γ < 1+1/c-1/(2αc) and β < αc +7/6- αγc-1/3(6α + 6αc + 1- 6αγc)^(1/2), we can perform cryptanalytic attacks based on the LLL algorithm. The basic idea is an application of Coppersmith's techniques and we further adapt the technique of unravelled linearization, which leads to an optimized lattice.Our advantage is that we achieve new attacks on RSA with α 0.5 and consequently, there exist weak keys in RSA for most α. | Mengce ZHENG Honggang HU Zilong WANG | 2016 | Science China(Information Sciences)2016，59，3： | 1 |
| 9 | On a Class of Pseudorandom Sequences from Elliptic Curves over Finite Fields显示文摘 | Hu Honggang Hu Lei Feng Dengguo | 2007 | IEEE Transactions on Information Theory2007，53，2： | 1 |
| 10 | Dissimi- lar metal joining of aluminum alloy to galvanized steel with A1-Si, A1-Cu,A1-Si-Cu and Zn-A1 filler wires显示文摘 | Dong Honggang Hu Wenjin Duan Yuping | 2012 | J Mater Processing Techn2012，212，： | 1 |
| 11 | Efficient Pairing Computation on Twisted Weierstrass Curves显示文摘In this paper, we construct the twists of twisted Edwards curves in Weierstrass form. Then we define a new twisted Ate pairing on twisted Weierstrass curves named the Tx-Ate pairing. Following Miller's algorithm, we give a computation of the Tx-Ate pairing on high degree twisted Weierstrass curves, where the point operations are over Edwards form, and the computation of Miller function is over Weierstrass form. Although, in one doubling loop, our method to compute the Tx-Ate pairing is a litter slower than the previously fastest method.By twists, the Tx-Ate pairing can be calculated on more twisted Weierstrass curves with short loop length. The TxAte pairing is even competitive with optimal Ate pairing when they have the same short loop length. | WANG Bei OUYANG Yi HU Honggang | 2018 | Chinese Journal of Electronics2018，27，4： | 1 |
| 12 | Periods on Two Kinds of Nonlinear Feedback Shift Registers with Time Varying Feedback Functions显示文摘 | Hu Honggang | 2011 | International Journal of Foundations of Computer Science2011，22，6： | 1 |
| 13 | Dissimilar metal joining of aluminum alloy to galvanized steel with AI-Si, A1-Cu, A1-Si-Cu, and Zn-A1 filler wires显示文摘 | DONG Honggang HU Wenjin DUAN Yuping | 2012 | Journal of Materials Processing Technology2012，212，2： | 1 |
| 14 | First identification of xanthone sulfonamides as potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors显示文摘 | Honggang Hu Hongli Liao Jun Zhang Weifeng Wu Jufang Yan Yonghong Yan Qingjie Zhao Yan Zou Xiaoyun Chai Shichong Yu Qiuye Wu | 2010 | Bioorganic & Medicinal Chemistry Letters2010，，10： | 1 |
| 15 | Dissimilar metal joining of aluminum alloy to galvanized steel with Al–Si, Al–Cu, Al–Si–Cu and Zn–Al filler wires显示文摘 | Honggang Dong Wenjin Hu Yuping Duan Xudong Wang Chuang Dong | 2011 | Journal of Materials Processing Tech2011，，2： | 1 |
| 16 | Numerical simulation on flow, combustion and heat transfer of eth- ylene cracking furnaces 显示文摘 | Hu Guihua Wang Honggang Qian Feng | 2011 | Chemical Engineering Sci- ence2011，66，： | 1 |
| 17 | A scoring system for prediction of early recurrence after liver resection for Barcelona Clinic Liver Cancer stage B hepatocellular carcinoma显示文摘 | Qian Honggang Wei Meng Qiu Hu Wu Jianhui Liu Bonan Lyu Ang Liu Qiao Li Chengpeng Leng Jiahua | 2014 | Chinese Medical Journal2014，，24： | 1 |
| 18 | On quadratic Bent functions in polynomial forms 显示文摘 | Hu Honggang Feng Dengguo | 2007 | IEEE Trans on Inform Theory2007，53，7： | 1 |
| 19 | Numerical simulation on flow,combustion and heat transfer of ethylene cracking furnaces显示文摘 | Hu Guihua Wang Honggang Qian Feng | | 0，，08： | 1 |
| 20 | Progress in studies on the DEK protein and its involvement in cellular apoptosis显示文摘DEK protein is an ubiquitous phosphorylated nuclear protein.Specific binding of DEK to DNA could change the topology of DNA and then affect the gene activity of the underlying DNA sequences.It is speculated that there might be some potential relationship between the stress reaction of cells and DEK proteins.The phosphorylation status of DEK protein is altered during death-receptor-mediated cell apoptosis.Both phosphorylation and poly(ADP-ribosyl)ation could promote the release of DEK from apoptotic nuclei to extracellular environment,and in this case DEK becomes a potential autoantigen of some autoimmune diseases.The available evidence powerfully suggests that DEK protein is closely relevant to apoptosis.The overexpression of DEK protein has dual function in cell apoptosis,in terms of inhibiting or triggering cell apoptosis. | HUA Ying,HU HongGang & PENG XiangLei College of Life Sciences and Bioengineering,School of Science,Beijing Jiaotong University,Beijing 100044,China | 2009 | Science China(Life Sciences)2009，52，7： | 1 |
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