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| 1 | An Overview on Advanced Grid-connected Inverters Used for Decentralized Renewable Energy Resources显示文摘并网逆变器是分散式可再生能源接入配电网的重要接口,随着分布式可再生能源渗透率的不断提高,并网逆变器在传统配电网中的地位越发突出。为了高效完成可再生能源分散式并网,并有效降低并网逆变器对电网的冲击,一些在装置上、结构上和功能上更加先进的并网逆变器成为了迫切的需求。针对现有的一些先进并网逆变器进行比较、分析和研究,从装置级、功能级和控制级的角度对现有先进并网逆变器进行综述。给出一些在结构上能更加灵活地将可再生能源分散接入配电网的硬件电路。研究一些适用于可再生能源分散接入的,使并网逆变器能虚拟同步发电机完成自治运行、电能质量治理、系统阻抗检测、网络阻抗控制等辅助控制功能。同时还对并网逆变器的并网同步算法和电流跟踪控制策略进行了探讨。最后,提出一个适合于可再生能源分散并网的先进并网逆变器框架。 | ZENG Zheng ZHAO Rongxiang TANG Shengqing YANG Huan LU Zhipeng | 2013 | 中国电机工程学报2013，33，24： | 76 |
| 2 | Coinfection with influenza A virus enhances SARS-CoV-2 infectivity显示文摘The upcoming flu season in the Northern Hemisphere merging with the current COVID-19 pandemic raises a potentially severe threat to public health.Through experimental coinfection with influenza A virus(IAV)and either pseudotyped or live SARS-CoV-2 virus,we found that IAV preinfection significantly promoted the infectivity of SARS-CoV-2 in a broad range of cell types.Remarkably,in vivo,increased SARS-CoV-2 viral load and more severe lung damage were observed in mice coinfected with IAV.Moreover,such enhancement of SARS-CoV-2 infectivity was not observed with several other respiratory viruses,likely due to a unique feature of IAV to elevate ACE2 expression.This study illustrates that IAV has a unique ability to aggravate SARS-CoV-2 infection,and thus,prevention of IAV infection is of great significance during the COVID-19 pandemic. | Lei Bai Yongliang Zhao Jiazhen Dong Simeng Liang Ming Guo Xinjin Liu Xin Wang Zhixiang Huang Xiaoyi Sun Zhen Zhang Lianghui Dong Qianyun Liu Yucheng Zheng Danping Niu Min Xiang Kun Song Jiajie Ye Wenchao Zheng Zhidong Tang Mingliang Tang Yu Zhou Chao Shen Li Zhou Yu Chen Huan Yan Ke Lan Ke Xu | 2021 | Cell Research2021，31，4： | 16 |
| 3 | Behavior of Mold Slag Used for 20Mn23Al Nonmagnetic Steel During Casting显示文摘Because of the addition of significant quantities of aluminum and manganese,the great challenge of casting 20Mn23Al nonmagnetic steel is to design a mold slag that is chemically compatible with this steel composition.A new mold slag with low melting point and low basicity was proposed.The initial slag(the base mold slag)and two corresponding mold slags sampled after 8 min and 15 min were investigated,and the changes of mold slag composition and properties of molten slag were discussed.The results showed that the slag quickly changed in chemical composition to a slag that contained a small quantity of silica and a larger quantity of alumina,and the basicity increased obviously;the heat flux density through the slag film decreased slightly compared with the slag film at 0 min,8 min and 15 min;the mold slag used for nonmagnetic steel was precipitated as CaF2 crystals.The casting experiment shows that the slab has good surface quality without longitudinal face cracks and slag inclusions;the Al2O3 content in the molten slag pool increased with time at the beginning stage,and it can approach equilibrium state after about 600 s. | YU Xiong WEN Guang-hua TANG Ping MA Fan-jun WANG Huan | 2011 | Journal of Iron and Steel Research(International)2011，18，1： | 15 |
| 4 | Evolution of boundary layer ozone in Shijiazhuang,a suburban site on the North China Plain显示文摘The structure of the boundary layer affects the evolution of ozone(O3), and research into this structure will provide important insights for understanding photochemical pollution.In this study, we conducted a one-month observation(from June 15 to July 14, 2016) of the boundary layer meteorological factors as well as O3 and its precursors in Luancheng County,Shijiazhuang(37°53′N, 114°38′E). Our research showed that photochemical pollution in Shijiazhuang is serious, and the mean hourly maximum and mean 8-hr maximum O3 concentrations are 97.9 ± 26.1 and 84.4 ± 22.4 ppbV, respectively. Meteorological factors play a significant role in the formation of O3. High temperatures and southeasterly winds lead to elevated O3 values, and at moderate relative humidity(40%–50%) and medium boundary layer heights(1200–1500 m), O3 production sensitivity occurred in the transitional region between volatile organic compounds(VOC) and nitrogen oxides(NOx) limitations,and the O3 concentration was the highest. The vertical profiles of O3 were also measured by a tethered balloon. The results showed that a large amount of O3 was stored in the residual layer, and the concentration was positively correlated with the O3 concentration measured the previous day. During the daytime of the following day, the contribution of O3 stored in the residual layer to the boundary layer reached 27%± 7% on average. | Wei Zhao Guiqian Tang Huan Yu Yang Yang Yinghong Wang Lili Wang Junlin An Wenkang Gao Bo Hu Mengtian Cheng Xingqin An Xin Li Yuesi Wang | 2019 | Journal of Environmental Sciences2019，31，9： | 15 |
| 5 | Enriching short text representation in microblog for clustering显示文摘社会媒介网站允许用户交换短文章例如在友谊网络经由 microblogs 和用户地位鸣叫。他们的有限长度,弥漫的缩写,和制造缩略词和词加重同义和一词多义的问题,并且引起新挑战到象聚类的文本和分类那样的数据采矿应用程序。处理这些问题,我们把一些潜在的原因并且设计由采用机器翻译从不同语言增加特征的数字充实数据表示的一条有效途径。然后,我们建议通过矩阵因式分解技术同时执行多语言知识集成和特征减小的一个新奇框架。建议途径从 Facebook 和 Twitter 在二社会媒介数据集上以有效性广泛地被评估。与它的重要表演改进,我们进一步调查贡献改进表演的潜在的因素。 | Jiliang TANG Xufei WANG Huiji GAO Xia HU Huan LIU | 2012 | Frontiers of Computer Science2012，6，1： | 14 |
| 6 | LA-ICP-MS Zircon U-Pb Dating of Intermediate-Acidic Intrusive Rocks and Molybdenite Re-Os Dating from the Bangpu Mo (Cu) Deposit, Tibet and its Geological Implication显示文摘The multi-stage intrusions of intermediate-acid magma occur in the Bangpu mining district, the petrogenic ages of which have been identified. The times and sequences of their emplacement have been collated and stipulated in detail in this paper by using the laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) zircon U-Pb dating method. The ages of biotite monzogranite that were formed before mineralization in the southwest of this mining district are 70±1 Ma (mean square of weighted deviates (MSWD) =9.5, n=8) and 60.60±0.31 Ma (MSWD=3.8, n=16), which belong to the late Cretaceous-early Paleocene in age. That means, they are products of an early tectonicmagmatic event of the collision between the Indian and Asian continentals. The ages of ore-bearing monzogranite porphyry and ore-bearing diorite porphyrite are 16.23±0.19 Ma (MSWD=2.0, n=26) and 15.16±0.09 Ma (MSWD=3.9, n=5) separately, which belong to the middle Miocene in age; namely, they are products of the Gangdese post-collision extensional stage when crust-mantle materials melted and mixed as well as magmatic intrusion simultaneously occurred. Some zircons with ages of 203.6±2.2 Ma (MSWD=1.18, n=7) were captured in the ore-bearing diorite porphyrite, which shows that there had been tectono-magmatic events in the late Triassic-early Jurassic. Molybdenum (copper) ore-bodies produced in the monzogranite porphyry and copper (molybdenum) ore-bodies produced in the diorite porphyrite are the main ore types in this ore deposit. The model ages of Re-Os isotopic dating for the 11 molybdenite are 13.97-15.84 Ma, while isochron ages are 14.09±0.49 Ma (MSWD=26). The isochron ages of seven molybdenite from molybdenum (copper) ore with monzogranite porphyry type are 14.11±0.31 Ma (MSWD=5.2). There is great error in the isochron ages of four molybdenite from copper (molybdenum) ore with diorite porphyrite type, and their weighted average model ages of 14.6±1.2 Ma (MSWD=41), which generally represent the mineralization age. The results about the Re-Os isotopic dating of molybdenite in the ore of different types have limited exactly that, the minerlazation age of this ore deposits is about 14.09 Ma, which belongs to the middle Miocene mineralization. The Bangpu deposit has a uniform metallogenic dynamics background with the porphyry type and skarn-type deposits such as Jiama, Qulong and others. | WANG Liqiang CHEN Yuchuan TANG Juxing LU Pengrui LUO Maocheng WANG Huan CHEN Wei LENG Qiufeng | 2012 | Acta Geologica Sinica(English Edition)2012，86，5： | 13 |
| 7 | Estimating grassland LAI using the Random Forests approach and Landsat imagery in the meadow steppe of Hulunber, China显示文摘Leaf area index(LAI) is a key parameter for describing vegetation structures and is closely associated with vegetative photosynthesis and energy balance. The accurate retrieval of LAI is important when modeling biophysical processes of vegetation and the productivity of earth systems. The Random Forests(RF) method aggregates an ensemble of decision trees to improve the prediction accuracy and demonstrates a more robust capacity than other regression methods. This study evaluated the RF method for predicting grassland LAI using ground measurements and remote sensing data. Parameter optimization and variable reduction were conducted before model prediction. Two variable reduction methods were examined: the Variable Importance Value method and the principal component analysis(PCA) method. Finally,the sensitivity of RF to highly correlated variables was tested. The results showed that the RF parameters have a small effect on the performance of RF,and a satisfactory prediction was acquired with a root mean square error(RMSE) of 0.1956. The two variable reduction methods for RF prediction produced different results; variable reduction based on the Variable Importance Value method achieved nearly the same prediction accuracy with no reduced prediction,whereas variable reduction using the PCA method had an obviously degraded result that may have been caused by the loss of subtle variations and the fusion of noise information. After removing highly correlated variables,the relative variable importance remained steady,and the use of variables selected based on the best-performing vegetation indices performed better than the variables with all vegetation indices or those selected based on the most important one. The results in this study demonstrate the practical and powerful ability of the RF method in predicting grassland LAI,which can also be applied to the estimation of other vegetation traits as an alternative to conventional empirical regression models and the selection of relevant variables used in ecological models. | LI Zhen-wang XIN Xiao-ping TANG Huan YANG Fan CHEN Bao-rui ZHANG Bao-hui | 2017 | Journal of Integrative Agriculture2017，16，2： | 11 |
| 8 | Dynamic immune profiling identifies the stronger graft-versus-leukemia (GVL) effects with haploidentical allografts compared to HLA-matched stem cell transplantation显示文摘Haploidentical stem cell transplantation(haplo-SCT)achieves superior or at least comparable clinical outcomes to HLA-matched sibling donor transplantation(MSDT)in treating hematological malignancies.To define the underlying regulatory dynamics,we analyzed time courses of leukemia burden and immune abundance of haplo-SCT or MSDT from multiple dimension.First,we employed two nonirradiated leukemia mouse models which carried human AML-ETO or MLL-AF9 fusion gene to establish haplo-identical and major histocompatibility(MHC)-matched transplantation models and investigated the immune cell dynamic response during leukemia development in vivo.We found that haplo-matching the MHCs of leukemia cells with recipient mouse T cells prolonged leukemic mice survival and reduced leukemia burden.The stronger graft-versus-leukemia activity in haplo-SCT group mainly induced by decreased apoptosis and increased cytotoxic cytokine secretion including tumor necrosis factor–α,interferon-γ,pore-forming proteins and CD107a secreted by T cells or natural killer cells.Furthermore,we conducted a prospective clinical trial which enrolled 135 patients with t(8;21)acute myeloid leukemia that displayed minimal residual disease before transplantation and underwent either haplo-SCT or MSDT.The results showed that the haplo-SCT slowed the kinetics of the leukemia burden in vivo and reduced the cumulative incidence of relapse compared with MSDT.Ex vivo experiments showed that,1 year after transplantation,cytotoxic T lymphocytes from the haplo-SCT group had higher cytotoxicity than those from the MSDT group during the same period.Our results unraveled the role of immune cells in superior antileukemia effects of haplo-SCT compared with MSDT. | Huidong Guo Ying-Jun Chang Yan Hong Lan-Ping Xu Yu Wang Xiao-Hui Zhang Ming Wang Huan Chen Yu-Hong Chen Feng-Rong Wang Wei-Han Yu-Qian Sun Chen-Hua Yan Fei-Fei Tang Xiao-Dong Mo Kai-Yan Liu Xiao-Jun Huang | 2021 | Cellular & Molecular Immunology2021，18，5： | 11 |
| 9 | Low-Dimensional Halide Perovskites and Their Advanced Optoelectronic Applications显示文摘Metal halide perovskites are crystalline materials originally developed out of scientific curiosity. They have shown great potential as active materials in optoelectronic applications. In the last 6 years, their certified photovoltaic efficiencies have reached 22.1%. Compared to bulk halide perovskites, low-dimensional ones exhibited novel physical properties. The photoluminescence quantum yields of perovskite quantum dots are close to 100%. The external quantum efficiencies and current efficiencies of perovskite quantum dot light-emitting diodes have reached 8% and 43 cd A^(-1),respectively, and their nanowire lasers show ultralow-threshold room-temperature lasing with emission tunability and ease of synthesis. Perovskite nanowire photodetectors reached a responsivity of 10 A W^(-1)and a specific normalized detectivity of the order of 10^(12 )Jones. Different from most reported reviews focusing on photovoltaic applications, we summarize the rapid progress in the study of low-dimensional perovskite materials, as well as their promising applications in optoelectronic devices. In particular, we review the wide tunability of fabrication methods and the state-of-the-art research outputs of low-dimensional perovskite optoelectronic devices. Finally, the anticipated challenges and potential for this exciting research are proposed. | Jian Zhang Xiaokun Yang Hui Deng Keke Qiao Umar Farooq Muhammad Ishaq Fei Yi Huan Liu Jiang Tang Haisheng Song | 2017 | Nano-Micro Letters2017，9，3： | 10 |
| 10 | Cloning and characterization of squalene synthase and cycloartenol synthase from Siraitia grosvenorii显示文摘Mogrosides and steroid saponins are tetracyclic triterpenoids found in Siraitia grosvenorii.Squalene synthase(SQS) and cycloartenol synthase(CAS) are key enzymes in triterpenoid and steroid biosynthesis.In this study,full-length cDNAs of SgSQS and SgCAS were cloned by a rapid amplification of cDNA-ends with polymerase chain reaction(RACE-PCR) approach.The SgSQS cDNA has a 1254 bp open reading frame(ORF) encoding 417 amino acids,and the SgCAS cDNA contains a 2298 bp ORF encoding 765 amino acids.Bioinformatic analysis showed that the deduced SgSQS protein has two transmembrane regions in the C-terminal.Both SgSQS and SgCAS have significantly higher levels in fruits than in other tissues,suggesting that steroids and mogrosides are competitors for the same precursors in fruits.Combined in silico prediction and subcellular localization,experiments in tobacco indicated that SgSQS was probably in the cytoplasm or on the cytoskeleton,and SgCAS was likely located in the nucleus or cytosol.These results will provide a foundation for further study of SgSQS and SgCAS gene functions in S.grosvenorii,and may facilitate improvements in mogroside content in fruit by regulating gene expression. | Huan Zhao Qi Tang Changming Mo Longhua Bai Dongping Tu Xiaojun Ma | 2017 | Acta Pharmaceutica Sinica B2017，7，2： | 10 |
| 11 | Pharmacokinetics and pharmacodynamics of Shengjiang decoction in rats with acute pancreatitis for protecting against multiple organ injury显示文摘AIM To explore the pharmacokinetics and pharmacodynamics of Shengjiang decoction(SJD) in rats with acute pancreatitis(AP) for protecting against multiple organ injury.METHODS An AP model was established by retrograde perfusion of 3.5% sodium taurocholate into the biliopancreatic duct, and a control group(CG) received 0.9% sodium chloride instead. Twelve male Sprague-Dawley rats were randomly divided into a CG treated with SJD(CG + SJD) and a model group treated with SJD(MG + SJD), both of which were orally administered with SJD(5 g/kg) 2 h after surgery. Blood samples were collected via the tail vein at 10, 20, and 40 min and 1, 2, 3, 4, 6, 8, and 12 h after a single dose of SJD to detect its main components using high-performance liquid chromatography-tandem mass spectrometry. The pharmacokinetic parameters were compared. In the pharmacodynamic experiment, 18 male SpragueDawley rats were randomly divided into a CG, an AP model group(MG), and an SJD treated AP group(SJDG). Serum amylase, lipase, and inflammatory cytokines were measured, and heart, lung, liver, spleen, pancreas, kidney, and intestine tissues were collected for pathological examination.RESULTS The MG + SJD displayed significantly shorter mean residence time(MRT) and higher clearance(CL) for emodin and aloe-emodin; significantly shorter time of maximum concentration and T1/2 and a lower area under curve(AUC) for aloe-emodin; a significantly higher AUC and lower CL for rhein; and longer MRT and lower CL for chrysophanol than the CG + SJD. In the pharmacodynamic experiment, the amylase, interleukin(IL)-6, IL-10, and tumor necrosis factor(TNF)-α levels in the MG were higher than those in the CG(P < 0.05). After the herbal decoction treatment, the SJDG had higher IL-10 and lower TNF-α levels than the MG(P < 0.05). The MG had the highest pathological scores, and the pathological scores of the lung, pancreas, kidney, and intestine in the SJDG were significantly lower than those in the MG(P < 0.05).CONCLUSION AP may have varying effects on the pharmacokinetics of the major SJD components in rats. SJD might alleviate pathological injuries of the lung, pancreas, kidney, and intestine in rats with AP via regulating pro-and antiinflammatory responses, which might guide the clinical application of SJD for AP treatment. | Lv Zhu Jun-Yi Li Yu-Mei Zhang Hong-Xin Kang Huan Chen Hang Su Juan Li Wen-Fu Tang | 2017 | World Journal of Gastroenterology2017，23，46： | 10 |
| 12 | Effects of Coal Rank and High Organic Sulfur on the Structure and Optical Properties of Coal-based Graphene Quantum Dots显示文摘Coal-based graphene quantum dots(GQDs) were successfully produced via a one-step chemical synthesis from six different coal ranks, from which two superhigh organic sulfur(SHOS) coals were selected as natural S-doped carbon sources for the preparation of S-doped GQDs. The effects of coal properties on coal-based GQDs were analyzed by means of high-resolution transmission electron microscopy(HRTEM), X-ray diffraction(XRD), Fourier transform infrared(FTIR) spectroscopy, X-ray photoelectron spectroscopy(XPS), ultraviolet-visible(UV-Vis) absorption spectroscopy, and fluorescence emission spectra. It was shown that all coal samples can be used to prepare GQDs, which emit bluegreen and blue fluorescence under ultraviolet light. Anthracite-based GQDs have a hexagonal crystal structure without defects, the largest size, and densely arranged carbon rings in their lamellae; the highrank bituminous coal-based GQDs are relatively reduced in size, with their hexagonal crystal structure being only faintly visible; the low-rank bituminous coal-based GQDs are the smallest, with sparse lattice fringes and visible internal defects. As the metamorphism of raw coals increases, the yield decreases and the fluorescence quantum yield(QY) initially increases and then decreases. Additionally, the surface of GQDs that were prepared using high-rank SHOS coal(high-rank bituminous coal) preserves rich sulfur content even after strong oxidation, which effectively adjusts the bandgap and improves the fluorescence QY. Thus, high-rank bituminous coal with SHOS content can be used as a natural S-doped carbon source to prepare S-doped GQDs, extending the clean utilization of low-grade coal. | TANG Yuegang HUAN Xuan LAN Chunyuan XU Miaoxin | 2018 | Acta Geologica Sinica(English Edition)2018，92，3： | 10 |
| 13 | Thermodynamic modeling and phase diagram prediction of salt lake brine systems.Ⅰ. Aqueous Mg^2+–Ca^2+–Cl^- binary and ternary systems显示文摘Salt lake brine is a complex salt-water system under natural environment.Although many models can express the thermodynamic properties and phase equilibrium of electrolyte aqueous solution,the multi-temperature characteristics and predictability are still the goals of model development.In this study,a comprehensive thermodynamic model system is re-established based on the eNRTL model and some improvements:(1) new expression of long-range electrostatic term with symmetrical reference state is proposed to handle the electrolyte solution covering entire concentration range;(2) the temperature dependence of the binary interaction parameters is formulated with a Gibbs Helmholtz expression containing three temperature coefficients,the liquid parameters,which associated with Gibbs energy,enthalpy,and heat capacity contribution;and(3) liquid parameters and solid species data are regressed from properties and solubility data at full temperature range.Together the activity coefficient model,property models and parameters of liquid and solid offer a comprehensive thermodynamic model system for the typical bittern of MgCl2-CaCl2-H2 O binary and ternary systems,and it shows excellent agreement with the literature data for the ternary and binary systems.The successful prediction of complete phase diagram of ternary system shows that the model has the ability to deal with high concentration and high non-idealitv system,and the ability to extrapolate the temperature. | Huan Zhou Xiaolong Gu Yaping Dai Jingjing Tang Jian Guo Guangbi Li Xiaoqin Bai | 2020 | Chinese Journal of Chemical Engineering2020，28，9： | 9 |
| 14 | Polymorphisms of three gene-derived STS on pig chromosome 13q41 are associated with susceptibility to enterotoxigenic Escherichia coli F4ab/ac in pigs显示文摘Neonatal diarrhea caused by enterotoxigenic Escherichia coli(ETEC)F4 is a common and serious disease,resulting in significant economical loss in the pig industry.The locus encoding ETEC F4 receptor has been mapped to pig chromosome(SSC)13q41,and one of the most significantly linked markers is S0075.In this study,we selected three genes including SLC12A8,MYLK and KPNA1 from a chromosomal region flanking S0075 on SSC13 to develop pig specific sequence tagged sites(STS). Seven single nucleotide polymorphisms were identified in the three pig STS using DNA of four full-sib susceptible and resistant animals in a White Duroc×Erhualian intercross.All grandparents,parents and 755 offspring in the intercross were genotyped for three polymorphisms,including SLC12A8 g.159A>G,MYLK g.1673A>G and KPNA1 g.306A>G.Family-based transmission disequilibrium test(TDT) revealed that all polymorphisms and the corresponding haplotypes are significantly associated with ETEC F4ab/ac(especially F4ac)brush border adhesion phenotypes,indicating that these polymor- phism are in linkage disequlibrium with causal mutation(s)of the gene encoding ETEC F4ab/ac receptor. Our results strengthen the evidence for the involvement of SSC13q41 in high acquiring risk of ETEC F4ab/ac infection,and provide novel polymorphic markers for fine mapping of the ETEC F4ab/ac receptor locus. | HUANG Xiang 1 ,REN Jun 1 ,YAN XueMing 1,2 ,PENG QiuLing 1 ,TANG Huan 1 ,ZHANG Bo 1 ,JI HuaYuan 1 , YANG ShuJin1&HUANG LuSheng 1 1Key Laboratory for Animal Biotechnology of Jiangxi Province and the Ministry of Agriculture of China,Jiangxi Agricultural University, Nanchang 330045,China 2Department of Biology,Nanchang University of Science and Technology,Nanchang 330038,China | 2008 | Science China(Life Sciences)2008，51，7： | 8 |
| 15 | Prediction of the globally ecological suitability of Panax quinquefolius by the geographic information system for global medicinal plants(GMPGIS)显示文摘American ginseng(Panax quinquefolius L.) is a well-known Asian traditional herbal medicine with a large market demand. The plant is native to eastern North America, and its main producing areas worldwide are decreasing due to continuous cropping obstacles and environmental changes. Therefore, the identification of maximum similarities of new ecological distribution of P.quinquefolius, and prediction of its response to climate change in the future are necessary for plant introduction and cultivation. In this study, the areas with potential ecological suitability for P. quinquefolius were predicted using the geographic information system for global medicinal plants(GMPGIS) based on 476 occurrence points and 19 bioclimatic variables. The results indicate that the new ecologically suitable areas for P. quinquefolius are East Asia and the mid-eastern Europe, which are mainly distributed in China, Russia, Japan, Ukraine, Belarus, North Korean, South Korea, and Romania. Under global climate change scenarios, the suitable planting areas for P. quinquefolius would be increased by 9.16%–30.97%, and expanding north and west over the current ecologically suitable areas by 2070. The potential increased areas that are ecologically suitable include northern Canada, Eastern Europe, and the Lesser Khingan Mountains of China, and reduced regions are mainly in central China, the southern U.S., and southern Europe. Jackknife tests indicate that the precipitation of the warmest quarter was the important climatic factor controlling the distribution of P. quinquefolius.Our findings can be used as a useful guide for P. quinquefolius introduction and cultivation in ecologically suitable areas. | SHEN Liang LI Xi-Wen MENG Xiang-Xiao WU Jie TANG Huan HUANG Lin-Fang XIAO Shui-Ming XU Jiang CHEN Shi-Lin | 2019 | Chinese Journal of Natural Medicines2019，17，7： | 7 |
| 16 | Homozygous loss-of-function mutations in FSIP2 cause male infertility with asthenoteratospermia显示文摘Male infertility, as a major issue of human reproduction health, prevents successful natural conception. Asthenoteratospermia mainly presents one or multiple anomalies in head, neck and tail of spermatozoa, and impairs sperm function and motility (Coutton et al., 2015). Recurrent abnormalities of the fibrous sheath lead to multiple morphological abnormaliries of the sperm flagella (MMAF), which is a quite frequent type of asthenoteratospermia in male infertility (Chemes et al., 1987;Ben Khelifa et al, 2014). | Wangjie Liu Huan Wu Li Wang Xiaoyu Yang Chunyu Liu Xiaojin He Weiyu Li Jiajia Wang Yujie Chen Hongyan Wang Yang Gao Shuyan Tang Shenmin Yang Li Jin Feng Zhang Yunxi Cao | 2019 | Journal of Genetics and Genomics2019，46，1： | 7 |
| 17 | ^(40)Ar/^(39)Ar geochronology constraints on hydrocarbon accumulation and destruction periods in the Bankeng paleo-reservoir in the southern margin of the middle Yangtze block显示文摘The exact determination of isotopic ages of hydrocarbon accumulation,reconstruction and destruction periods using traditional isotopic dating methods is complex because of the small numbers of minerals that correlate with hydrocarbons.The quantitative and direct study of hydrocarbon geochronology is therefore an important scientific problem for isotope geochronology and petroleum geology.This study obtains two isotopic ages from a quartz vein sample associated with bitumen in a reverse fault located in the Bankeng paleo-reservoir on the southern margin of the middle Yangtze block (the northern margin of the JiangnanXuefeng uplift) by inclusion 40Ar/39Ar stepwise crushing in a vacuum.Two different and good linear inverse isochrons that correspond to two age plateaus were determined.The two ages correspond to primary inclusions of about 228 Ma and secondary inclusions of about 149 Ma.These inclusion groups represent two distinct kinds of fluids.Quartz veins associated with bitumen in faulted paleo-reservoirs,which have a strict response relationship with tectonization and hydrocarbon accumulation,are the unified products of tectonic processes,hydrocarbon accumulation and reconstruction.Therefore,they can be used to constrain the hydrocarbon accumulation,reconstruction and destruction periods that are controlled by multiphase and complicated tectonic actions.The evolutionary processes of hydrocarbon accumulation can be divided into two periods consisting of a primary oil and gas reservoir formation period in the late Indosinian epoch (about 228 Ma) and a period of oil and gas reservoir reconstruction in the early Yanshan epoch (about 149 Ma).This study quantitatively reconstructs the hydrocarbon accumulation and destruction chronological framework of a giant hydrocarbon accumulation belt along the southern margin of the middle Yangtze block (the northern margin of the Jiangnan-Xuefeng uplift) controlled by multiphase and complicated tectonism.The two ages associated with hydrocarbons here correspond to the special controlling actions of continental tectonics in the Jiangnan-Xuefeng uplift that affected the timeline of reconstruction and destruction in this giant marine hydrocarbon accumulation.This study shows the feasibility and usefulness of dating inclusions with the 40Ar/39Ar technique for hydrocarbon geochronology,especially in the marine hydrocarbon accumulation region of southern China within a geological setting of old strata,high thermal evolution hydrocarbons,and complex,multiphase and multicycle tectonization. | LIU ZhaoQian MEI LianFu QIU HuaNing SHEN ChuanBo TANG JiGuang YUN JianBing | 2011 | Chinese Science Bulletin2011，56，26： | 7 |
| 18 | Comparison of paleotemperature reconstructions using microbial tetraether thermometers of the Chinese loess-paleosol sequence for the past 350000 years显示文摘The recently proposed global and local calibrations for the mean annual air temperature(MAT) reconstruction on the basis of 5-and 6-methyl brGDGTs have rarely been applied to the Chinese LPS yet, leaving the applicability of these calibrations unclear. Here, we used the improved chromatography method to analyze 198 loess-paleosol samples from the Weinan section in the southern CLP for the past 350 kyr. The 6-methyl brGDGTs comprise a major proportion of total brGDGTs, pointing to alkaline conditions for most soil samples from the Weinan LPS. The decoupled profile variation of MBT′6ME and MBT′_(5ME) suggests their response to different enviromental factors, possibly soil pH(or soil moisture) and temperature, respectively. This discrimination further corraborates that temperature and monsoonal precipitation were not in phase during the last four deglaciations on the CLP. Temperature estimates for the six calibrations tested show similar trends but remarkably differ in amplitudes. The soil moisture appears to affect the global MBT′/CBT calibration, the global MATmr calibration(a calibration based on the multiple linear regression) and the Chinese local SSM(Stepwise Selection Method) calibration, resulting in a significant underestimation of late Holocene temperature. In contrast, the dry climate has no effect on the global MBT′5ME calibration. Of the six calibrations,only the Chinese local SSM calibration and global MATmr calibration produce temperature variation amplitude over the past 350 ka that is consistent with other independent proxy data. The recently proposed local calibrations based on 5-and 6-methyl brGDGTs for North China yield the amplitude of temperature changes that is much larger than the results determined by other approaches.All the six calibrations have their own weakness in the MAT reconstruction, due partly to the inconsistency between the brGDGT distribution in the Weinan LPS and the modern soils used to establish these calibrations. | TANG ChangYan YANG Huan DANG XinYue XIE ShuCheng | 2017 | Science China Earth Sciences2017，60，6： | 7 |
| 19 | Spatial Distribution of Liver Cancer Incidence in Shenqiu County,Henan Province,China:a Spatial Analysis显示文摘Liver cancer is a common and leading cause of cancer death in China.We used the cancer registry data collected from 2009 to 2011 to describe the spatial distribution of liver cancer incidence at village level in Shengqiu county,Henan province,China.Spatial autocorrelation analysis was employed to detect significant differences from a random spatial distribution of liver cancer incidence.Spatial scan statistics were used to detect and evaluate the clusters of liver cancer cases. | SUN Jie HUANG Hui XIAO Ge Xin FENG Guo Shuang YU Shi Cheng XUE Yu Tang WAN Xia YANG Gong Huan SUN Xin | 2015 | Biomedical and Environmental Sciences2015，28，3： | 7 |
| 20 | BACKGROUND: Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 (HMGB1) is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS: Sixty rats were randomly divided into a normal control group (group A, n=10) anda Vibrio vulnificus sepsis group (group B, n=50). Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus (concentration 6×108 cfu/mL, volume 0.1 mL/100g)) into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance(ANOVA) and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS: Compared to group A (0.652±0.177), HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour (1.161±0.358, P=0.013), 24 hours (1.679±0.235, P=0.000),and 48 hours (1.258±0.274, P=0.004) (P〈0.05), and peaked at 24 hours. Compared to group A(0.594±0.190), HMGB1 protein expression at 6 hours (1.408±0.567, P=0.026) after infection wassignificantly increased (P〈0. 05), and peaked at 24 hours (2.415±1.064, P=0.000) after infection.Compared to group A (0.699±0.054), lung water content was significantly increased at 6 hours(0.759±0.030, P=0.001),12 hours (0.767±0.023, P=0.000), 24 hours (0.771±0.043, P=0.000) and 48hours (0.789±0.137, P=0.000) after infection (P〈0.05). Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION: Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis.显示文摘BACKGROUND: Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 (HMGB1) is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS: Sixty rats were randomly divided into a normal control group (group A, n=10) anda Vibrio vulnificus sepsis group (group B, n=50). Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus (concentration 6×108 cfu/mL, volume 0.1 mL/100g)) into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance(ANOVA) and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS: Compared to group A (0.652±0.177), HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour (1.161±0.358, P=0.013), 24 hours (1.679±0.235, P=0.000),and 48 hours (1.258±0.274, P=0.004) (P〈0.05), and peaked at 24 hours. Compared to group A(0.594±0.190), HMGB1 protein expression at 6 hours (1.408±0.567, P=0.026) after infection wassignificantly increased (P〈0. 05), and peaked at 24 hours (2.415±1.064, P=0.000) after infection.Compared to group A (0.699±0.054), lung water content was significantly increased at 6 hours(0.759±0.030, P=0.001),12 hours (0.767±0.023, P=0.000), 24 hours (0.771±0.043, P=0.000) and 48hours (0.789±0.137, P=0.000) after infection (P〈0.05). Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION: Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. | Qiao-meng Qiu Zhong-wang Li Lu-ming Tang Qi Sun Zhong-qiu Lu Huan Liang Guang-liang Hong Meng-fang Li | 2011 | World Journal of Emergency Medicine2011，2，4： | 7 |
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