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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Sensory innervation around immediately vs. delayed loaded implants: a pilot study显示文摘Although neurophysiological and psychophysical proof of osseoperception is accumulating, histomorphometric evidence for the neural mechanisms of functional compensation following immediate and delayed implant loading is still lacking. For this randomized split-mouth study, six mongrel dogs randomly received one of four treatment protocols at 36 implant-recipient sites over 16 weeks(third maxillary incisor, third and fourth mandibular premolar): immediate implant placement and immediate loading(IIP1IL);delayed implant placement and delayed loading(DIP1DL); delayed implant placement and immediate loading(DIP1IL); and natural extraction socket healing(control). Histomorphometry was performed in the peri-implant bone and soft tissues within 300 mm around the implants. Immunocytochemistry and transmission electron microscopy were used to confirm the presence of neural structures and to reveal their ultrastructural characteristics, respectively. Myelinated nerve fibres densely populated the peri-implant crestal gingival and apical regions, although they were also identified in the woven bone and in the osteons near the implant threads. Compared with the control group in the mandible, the group that received IIP1 IL showed a higher innervation(in Nmm22, 5.9461.12 vs. 3.1560.63,P,0.001) and smaller fibre diameter(in mm, 1.3760.05 vs. 1.6460.13, P50.016), smaller axon diameter(in mm, 0.8960.05 vs.1.2460.10, P50.009) and g-ratio(0.6460.04 vs. 0.7660.05, P,0.001) in the middle region around the implants. Compared with DIP1 IL in the mandible, IIP1 IL had a higher nerve density(in Nmm22, 13.2362.54 vs. 9.6461.86, P50.027), greater fibre diameter(in mm, 1.3260.02 vs. 1.2060.04, P50.021), greater axon diameter(in mm, 0.9260.01 vs. 0.8960.03, P50.035) and lower g-ratio(0.6960.01 vs. 0.7460.01, P50.033) in the apical region around the implants. It may be assumed that the treatment protocol with IIP1 IL is the preferred method to allow optimized peri-implant re-innervation, but further functional measurements are still required. | Yan Huang Jeroen van Dessel Wendy Martens Ivo Lambrichts Wei-Jian Zhong Guo-Wu Ma Dan Lin Xin Liang Reinhilde Jacobs | 2015 | International Journal of Oral Science2015，7，1： | 7 |
| 3 | Sensitivity of Fusarium graminearum to Carbendazim and Prochloraz显示文摘[Objective]The paper was to understand the resistance of Fusarium graminearum to carbendazim and prochloraz in the main wheat producing areas in Hubei Province.[Method] Totally 350 F. graminearum strains isolated in 2014 were determined to clear their sensitivity to carbendazim and prochloraz. [Result]All isolates were sensitive to carbendazim and prochloraz in Hubei Province,and carbendazim was still valuable in controlling Fusarium head blight. The control effect of prochloraz was better than that of carbendazim,and the combination of prochloraz and carbendazim at the proportion of 1∶ 7 received the best control effect.[Conclusion]Combination of chemical agents will occupy a more and more important position in future prevention and control against Fusarium head blight. | Ma Dongfang Huang Shi Zhang Peng Sun Cai Huang Wendi Li Guangjun Zhang Changqing Fang Zhengwu | 2017 | Plant Diseases and Pests2017，8，1： | 2 |
| 4 | The impact of maternal weight discrepancies on prenatal screening results for Down syndrome 显示文摘 | Tianhua Huang Wendy S | 2013 | Prenat Diagn2013，3316，： | 1 |
| 5 | EMG biofeed- back effectiveness to alter muscle activity pattern and scapular kinemat- ics in subjects with and without shoulder impingeme,t 显示文摘 | Han-Yi Huang Jiu-Jenq Lin Yueliang Leon Guo Wendy | 2012 | Journal of Electromyography and Kinesiology2012，，： | 1 |
| 6 | Chronic Gastrointestinal Inflammation Induces Anxiety-Like Behavior and Alters Central Nervous System Biochemistry in Mice显示文摘 | Premysl Bercik Elena F. Verdu Jane A. Foster Joseph Macri Murray Potter Xiaxing Huang Paul Malinowski Wendy Jackson Patricia Blennerhassett Karen A. Neufeld Jun Lu Waliul I. Khan Irene Corthesy–Theulaz Christine Cherbut Gabriela E. Bergonzelli Stephen M. | 2010 | Gastroenterology2010，，6： | 1 |
| 7 | Long-Term Use of Aspirin and the Risk of Gastrointestinal Bleeding显示文摘 | Edward S. Huang Lisa L. Strate Wendy W. Ho Salina S. Lee Andrew T. Chan | 2011 | The American Journal of Medicine2011，，5： | 1 |
| 8 | Human mobility data in the COVID-19 pandemic:characteristics,applications,and challenges显示文摘The COVID-19 pandemic poses unprecedented challenges around the world.Many studies have applied mobility data to explore spatiotemporal trends over time,investigate associations with other variables,and predict or simulate the spread of COVID-19.Our objective was to provide a comprehensive overview of human mobility open data to guide researchers and policymakers in conducting data-driven evaluations and decision-making for the COVID-19 pandemic and other infectious disease outbreaks.We summarized the mobility data usage in COVID-19 studies by reviewing recent publications on COVID-19 and human mobility from a data-oriented perspective.We identified three major sources of mobility data:public transit systems,mobile operators,and mobile phone applications.Four approaches have been commonly used to estimate human mobility:public transit-based flow,social activity patterns,index-based mobility data,and social media-derived mobility data.We compared mobility datasets’characteristics by assessing data privacy,quality,space–time coverage,high-performance data storage and processing,and accessibility.We also present challenges and future directions of using mobility data.This review makes a pivotal contribution to understanding the use of and access to human mobility data in the COVID-19 pandemic and future disease outbreaks. | Tao Hu Siqin Wang Bing She Mengxi Zhang Xiao Huang Yunhe Cui Jacob Khuri Yaxin Hu Xiaokang Fu Xiaoyue Wang Peixiao Wang Xinyan Zhu Shuming Bao Wendy Guan Zhenlong Li | 2021 | International Journal of Digital Earth2021，14，9： | 1 |
| 9 | A Validated Regulatory Network for Th17 Cell Specification显示文摘 | Maria Ciofani Aviv Madar Carolina Galan MacLean Sellars Kieran Mace Florencia Pauli Ashish Agarwal Wendy Huang Christopher N. Parkurst Michael Muratet Kim M. Newberry Sarah Meadows Alex Greenfield Yi Yang Preti Jain Francis K. Kirigin Carmen Birchmeier Er | 2012 | Cell2012，，2： | 1 |
| 10 | Prevalence of CKD and Comorbid Illness in Elderly Patients in the United States: Results From the Kidney Early Evaluation Program (KEEP)显示文摘 | Lesley A. Stevens Suying Li Changchun Wang Cindy Huang Bryan N. Becker Andrew S. Bomback Wendy Weinstock Brown Nilka Ríos Burrows Claudine T. Jurkovitz Samy I. McFarlane Keith C. Norris Michael Shlipak Adam T. Whaley-Connell Shu-Cheng Chen George L. Bakri | 2010 | American Journal of Kidney Diseases2010，，3： | 1 |
| 11 | Prevalence of Human Papillomavirus Types in Invasive Cervical Cancers From 7 US Cancer Registries Before Vaccine Introduction显示文摘 | Claudia Hopenhayn Amy Christian Warren Jay Christian Meg Watson Elizabeth R. Unger Charles F. Lynch Edward S. Peters Edward J. Wilkinson Youjie Huang Glenn Copeland Wendy Cozen Maria Sibug Saber Marc T. Goodman Brenda Y. Hernandez Martin Steinau Christoph | 2014 | Journal of Lower Genital Tract Disease2014，，2： | 1 |
| 12 | Amylase and lipase measurements in paediatric patients with traumatic pancreatic injuries显示文摘 | Wendy C. Matsuno Craig J. Huang Nilda M. Garcia Lonnie C. Roy Jacqueline Davis | 2008 | Injury2008，，： | 1 |
| 13 | The impact of maternal weight discrepancies on prenatal screening results for Down syndrome显示文摘 | Tianhua Huang Wendy S. Meschino Nan Okun Alan Dennis Barry Hoffman Nathalie Lepage Shamim Rashid Ritu Aul Sandra A. Farrell | 2013 | Prenat Diagn2013，，5： | 1 |
| 14 | Human Papillomavirus Prevalence in Invasive Anal Cancers in the United States Before Vaccine Introduction显示文摘 | Martin Steinau Elizabeth R. Unger Brenda Y. Hernandez Marc T. Goodman Glenn Copeland Claudia Hopenhayn Wendy Cozen Maria S. Saber Youjie Huang Edward S. Peters Charles F. Lynch Edward J. Wilkinson Mangalathu S. Rajeevan Christopher Lyu Mona Saraiya | 2013 | Journal of Lower Genital Tract Disease2013，，4： | 1 |
| 15 | Factors associated with kyphosis progression in older women: 15 years’ experience in the study of osteoporotic fractures显示文摘 | Deborah M Kado Mei‐Hua Huang Arun S Karlamangla Peggy Cawthon Wendy Katzman Teresa A Hillier Kristine Ensrud Steven R Cummings | 2012 | J Bone Miner Res2012，，1： | 1 |
| 16 | Therapeutic effect of Qinghuayin(清化饮)against chronic atrophic gastritis through the inhibition of toll or interleukin-1 receptor domain-containing adaptor inducing interferon-β signaling pathway显示文摘OBJECTIVE:To examine the efficacy of Qinghuayin(清化饮,QHY)in rat chronic atrophic gastritis(CAG)models and explored the molecular mechanism of QHY in treating CAG.METHODS:In total,65 Wistar rats were randomly divided into the control(n=10)and CAG groups(n=55).CAG model rats were further divided into five groups:model(n=10),vitacoenzyme(n=10),low-dose QHY(n=10),medium-dose QHY(n=10),and high-dose QHY groups(n=10).We analyzed histopathological changes using hematoxylin and eosin staining and measured interleukin(IL)-6 and IL-8 levels in serum using enzyme-linked immunosorbent assay(ELISA)(Boster Bio,Pleasanton,USA).In addition,gastrin(GAS),pepsinogen I(PGI),and PGII expressions were evaluated using ELISA.The protein and m RNA expression of toll-like receptor 4(TLR4)and toll or interleukin-1 receptor domaincontaining adaptor inducing interferon-β(TRIF)was detected by Western blotting and quantitative reverse transcription-polymerase chain reaction,respectively.RESULTS:Our results revealed that histopathological changes in CAG model rates could be restored by low-,medium-,and high-dose QHY.The changes in GAS and PGI/II expression demonstrated that QHY improved CAG.Serum IL-6 and IL-levels were decreased by QHY administration.TLR4 and TRIF were upregulated at the m RNA and protein levels in the model group but downregulated by QHY administration.CONCLUSION:We concluded that QHY could effectively improve the histopathological changes of the gastric mucosa induced by CAG in rats.The therapeutic mechanism of QHY may be related to inhibition of the inflammatory factors IL-6 and IL-8 and suppression of TLR4/TRIF m RNA and protein expression. | HE Youcheng YAO Xiaoling LI Sihan ZHOU Hongjian XU Ruoying ZHENG Rong XIAO Wendi SU Ning LIN Ping HUANG Minghan | 2022 | Journal of Traditional Chinese Medicine2022，42，2： | 1 |
| 17 | Three lactic acid bacteria with anti-obesity properties:In vitro screening and probiotic assessment显示文摘The worldwide obesity epidemic has imposed human being a huge burden and attention had been drawn to manipulating the lactic acid bacteria (LAB) to improve obesity symptoms.In this study,a more comprehensive and reliable in vitro method was established to screen LAB with greater potential against obesity.Firstly,twenty-eight human feces-derived LAB strains were selected by assessing bile salt-acid tolerance and cholesterol lowering capacity.Subsequently,the triglyceride lowering capacity,bile salt hydrolase (BSH) activity,α-glucosidase activity inhibition capacity and Enterobacter cloacae (E.cloacae) growth inhibition capacity were tested for further evaluating the anti-obesity properties of LAB strains.Principal component analysis (PCA) of these results indicated that Limosilactobacillus reuteri (L.reuteri) NCUH003,Lactiplantibacillus plantarum (L.plantarum) NCUH046 and Limosilactobacillus fermentum (L.fermentum) NCUH068 exhibited favorable anti-obesity properties.Besides,the LAB displayed good gastrointestinal adaptability and antioxidant activity but no hemolytic activity,and they were sensitive to various antibiotics.These results indicated that L.reuteri NCUH003,L.plantarum NCUH046 and L.fermentum NCUH068 are potential for application in obesity treatment. | Benliang Wei Zhen Peng Muyan Xiao Tao Huang Wendi Zheng Mingyong Xie Tao Xiong | 2022 | Food Bioscience2022，47，3： | 0 |
| 18 | Corrosion mechanism of ceramic glaze from the Yangtze EstuaryⅡ显示文摘Ancient lead-glazed ceramics frequently corrode physically,chemically,and biologically when buried in soil,submerged in water,or exposed to air.In comparison to the other two environments,relatively little research has been conducted on how leadglazed ceramics deteriorate in the water environment.Four lead-glazed ceramic samples from the Yangtze EstuaryⅡwere examined for their micromorphology and structural composition using scanning electron microscopy-energy spectrum analysis,micro-area X-ray diffraction analysis,fluorescence microanalysis,and Fourier infrared spectroscopy analysis.The results demonstrate the formation of deposits of PbCO_(3),Pb(OH)Cl,and Cu FeS_(2)and corrosion pits and fractures on the glaze layer surfaces.According to the corrosion phenomenon,the lead glaze layers of ceramics mainly underwent chemical and microbial corrosion in water,and the corrosion process of the lead glaze was expounded and modeled.The research results deepen the understanding of the corrosion mechanism of lead-glazed ceramics,which is of great significance for the study of the conservation of lead-glazed ceramics and other types of ceramic relics and can also provide a reference for the long-term preservation of contemporary silicate products. | YU WenDi ZHAO Luo ZHAI Yang ZHAO Jing ZHANG KeXin GE Yan LI Qiang ZHAO Meng HUANG JiZhong LUO HongJie | 2023 | Science China(Technological Sciences)2023，66，8： | 0 |
| 19 | Ammonium Impacts on Vibrations of Hydroxyl and Lattice of Phengite at High Temperature and High Pressure显示文摘Dehydration in hydrous phases of the downgoing slab controls water release processes in subduction zones. Interplay between volatiles in hydrous minerals has complicated the previous knowledge of their dehydration. Phengite is an essential mineral carrying both hydrogen and nitrogen to the deep Earth. To further understand the link between nitrogen and dehydration process of phengite at an atomic level, we here carry out high temperature and high pressure vibrational spectroscopic investigations on hydroxyl and lattice of ammonium-bearing and ammonium-free phengites. The results show that heating to 800 oC hardly influences hydroxyl bonding strength, whereas pressure induces strengthening of hydrogen bonding until 10 GPa. Moreover, hydrogen transits between the sites with increasing temperature and pressure. The lattice modes soften with increasing temperature and stiffen under compression. Ammonium has no effect on hydroxyl bonding strength, but hinders hydrogen transition at high temperatures and high pressures. Ammonium does not influence the lattice at high pressures either, but delays softening of the lattice at high temperatures. These data unveil behavior of hydroxyl and lattice in phengite at high temperature and high pressure, and also evaluate ammonium impacts, shedding new lights on dehydration processes of phengite during subduction. | Weihua Huang Yan Yang Zeming Qi Wendi Liu Zhongping Wang Yan Liu Qunke Xia | 2021 | Journal of Earth Science2021，32，5： | 0 |
| 20 | Crystallography of low Z material at ultrahigh pressure:Case study on solid hydrogen显示文摘Diamond anvil cell techniques have been improved to allow access to the multimegabar ultrahigh-pressure region for exploring novel phenomena in condensedmatter.However,the onlyway to determine crystal structures of materials above 100 GPa,namely,X-ray diffraction(XRD),especially for lowZ materials,remains nontrivial in the ultrahigh-pressure region,even with the availability of brilliant synchrotron X-ray sources.In thiswork,we performa systematic study,choosing hydrogen(the lowest X-ray scatterer)as the subject,to understand how to better perform XRD measurements of low Z materials at multimegabar pressures.The techniques that we have developed have been proved to be effective in measuring the crystal structure of solid hydrogen up to 254GPa at room temperature[C.Ji et al.,Nature 573,558–562(2019)].Wepresent our discoveries and experienceswith regard to several aspects of thiswork,namely,diamond anvil selection,sample configuration for ultrahigh-pressure XRDstudies,XRDdiagnostics for low Z materials,and related issues in data interpretation and pressure calibration.Webelieve that these methods can be readily extended to other low Z materials and can pave the way for studying the crystal structure of hydrogen at higher pressures,eventually testing structural models of metallic hydrogen. | Cheng Ji Bing Li Wenjun Liu Jesse S.Smith Alexander Bjoorling Arnab Majumdar Wei Luo Rajeev Ahuja Jinfu Shu Junyue Wang Stanislav Sinogeikin Yue Meng Vitali B.Prakapenka Eran Greenberg Ruqing Xu Xianrong Huang Yang Ding Alexander Soldatov Wenge Yang Guoyin Shen Wendy L.Mao Ho-Kwang Mao | 2020 | Matter and Radiation at Extremes2020，5，3： | 0 |
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