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| 1 | Differing coping mechanisms, stress level and anorectal physiology in patients with functional constipation显示文摘AIM: To investigate coping mechanisms, constipation symptoms and anorectal physiology in 80 constipated subjects and 18 controls.METHODS: Constipation was diagnosed by Rome Ⅱ criteria.Coping ability and anxiety/depression were assessed by validated questionnaires. Transit time and balloon distension test were performed.RESULTS: 34.5% patients were classified as slow transit type of constipation. The total colonic transit time (56 h vs 10 h, P<0.0001) and rectal sensation including urge sensation (79 mL vs 63 mL, P = 0.019) and maximum tolerable volume (110 mL vs95 mL, P = 0.03) differed in patients and controls. Constipated subjects had significantly higher anxiety and depression scores and lower SF-36 scores in all categories. They also demonstrated higher scores of'monitoring' coping strategy (14+6 vs9+3, P = 0.001),which correlated with the rectal distension sensation (P = 0.005), urge sensation (P=0.002), and maximum tolerable volume (P = 0.035). The less use of blunting strategy predicted slow transit constipation in both univariate (P = 0.01) and multivariate analysis (P = 0.03).CONCLUSION: Defective or ineffective use of coping strategies may be an important etiology in functional constipation and subsequently reflected in abnormal anorectal physiology. | Annie OO Chan Cecilia Cheng Wai Mo Hui Wayne HC Hu Nina YH Wong KF Lam Wai Man Wong Kam Chuen Lai Shiu Kum Lam Benjamin CY Wong | 2005 | World Journal of Gastroenterology2005，11，34： | 92 |
| 2 | Escheriehia coli outer membrane protease OmpT con- fers resistance to urinary cationic peptides 显示文摘 | Hui CY Guo Y He QS Peng L Wu SC Cao H Huang SH | 2010 | Microbiol Immunol2010，54，8： | 1 |
| 3 | Inhibition of endothelium-dependent vascular relaxation by tetrandrine显示文摘 | KWAN CY MA FM HUI SC | 1999 | Life Sci1999，64，25： | 1 |
| 4 | Elevated circulating pig- ment epithelium-derived factor predicts the progression of diabetic nephropathy in patients with type 2 diabetes 显示文摘 | Hui E Yeung CY Lee PC | 2014 | J Clin Endocrinol Metab2014，99，11： | 1 |
| 5 | Elevated circulating pig-ment epithelium -derived factor predicts the progression of dia-betic nephropathy in patient with type 2 diabetes显示文摘 | Hui E Yeung CY Lee PC | 2014 | Clin En-dorinol Metab2014，99，11： | 1 |
| 6 | Elevated circulatingpigment epithelium-derived factor predicts the progression ofdiabetic nephropathy in patients with type 2 diabetes显示文摘 | Hui E Yeung CY Lee PC | 2014 | JClin Endocrinol Metab2014，99，11： | 1 |
| 7 | Inhibition of endothelium-dependent vascular relaxation by tetrandrine显示文摘 | Kwan CY Ma FM Hui SC | 1999 | Life Sci1999，64，25： | 1 |
| 8 | Escherichia coli outer membrane protease OmpT confers resistance to urinary cationic peptides显示文摘 | Hui CY Guo Y He QS | | 0，，08： | 1 |
| 9 | Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK 显示文摘 | Hui KP Lee SM Cheung CY | 2009 | J Immunol2009，182，2： | 1 |
| 10 | Increasing prevalence of advanced colonic polyps in young patients undergoing colonoscopy in a referral academic hospital in Hong Kong显示文摘AIM: To investigate the distribution and frequency of advanced polyps over eight years. METHODS: 6424 colonoscopies were reviewed during the study period 1998 to 2005. The study period was subdivided into period Ⅰ: 1998 to 2001 and period Ⅱ: 2002-2005. RESULTS: 1856 polyps (33% advanced polyps) and 328 CRCs were detected. The mean ages of the patients with advanced polyps and cancer were 69.2 ± 12.0 and 71.6 ± 13.8 years, respectively. Advanced polyps were mainly left sided (59.5%). Advanced polyps were found in patients ≤ 60 years from 17.7% in periodⅠto 26.3% in period Ⅱ (P < 0.05), especially in male subjects ≤ 60 years (21.6% vs 31.6%, P < 0.05). Advanced tubulovillous polyps rose from 21.5% in period Ⅰto 29.5% in period Ⅱ (P < 0.05). Whereas cancers in male patients ≤ 60 years were similar in both periods: 23.2% vs 16.5% (P > 0.05). CONCLUSION: Advanced polyps increased significantly in the younger male group in the most recent period and there seems to be a shift towards a proximal location. | Tze Jui Lam Benjamin CY Wong Chris JJ Mulder A Salvador Pea Wai Mo Hui Shiu Kum Lam Annie On On Chan | 2007 | World Journal of Gastroenterology2007，13，28： | 1 |
| 11 | Escherichia coli outer membrane protease OmpT confers resistance to urinary cationic peptides显示文摘 | Hui CY Guo Y He QS | 2010 | Microbiol Immunol2010，54，8： | 1 |
| 12 | Surface-freezing transitions and novel tilted hexatic phases in smectic liquid-crystal films显示文摘 | Chao CY Hui S W Maclennan J E ChouC F HoJ T | | 0，，： | 1 |
| 13 | Soluble E-cadherin is a valid prognostie marker in gastric carcinoma显示文摘 | Chan AO Lam SK Chu KM Lam CM Kwok E Leung SY Yuen ST Law SY Hui WM Lai KC Wong CY Hu HC Lai CL Wong J | | 0，，： | 1 |
| 14 | Escherichia coil outer membrane protease OmpT confers resistance to urinary cationic peptides 显示文摘 | Hui CY Guo Y He QS | 2010 | Microbiol Immunol2010，54，8： | 1 |
| 15 | Escherichia coli outer membrane protease OmpT confers resistance to urinary cationic peptides显示文摘 | Hui CY Guo Y He QS | | 0，，08： | 1 |
| 16 | Escherichia coli outer membrane protease OmpT confers resistance to urinary cationic peptides 显示文摘 | Hui CY Guo Y He QS | 2010 | Microbiol lmmuno12010，54，8： | 1 |
| 17 | The 50% and 95% effective doses of desflurane for removal of the classic laryngeal mask airway in sponta- neously breathing anaesthetised adults 显示文摘 | Hui MT Subash S Wang CY | 2011 | Anaesthesia2011，66，4： | 1 |
| 18 | Genetic and phenotypic characterization of drug-resistant Mycobacterium tuberculosis isolates in Hong Kong显示文摘 | Chan RC Hui M Chan EW Au TK Chin ML Yip CK AuYeang CK Yeung CY Kam KM Yip PC Cheng AF | 2007 | J Antlmicrobial Chemotherapy2007，59，5： | 1 |
| 19 | Oligodeoxyribonucleotides derived from salmon sperm DNA: an alternative to defibrotide 显示文摘 | Hui CY Guo Y Zhang X | 2013 | Biologicals2013，41，3： | 1 |
| 20 | Intense pulsed light for the treatment of refractory melasma in Asian patients显示文摘 | Wang CC Hui CY Sue YM | 2004 | Dermatol Surg2004，30，9： | 1 |
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