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| 1 | A nomogramfor predicting overall survival in patients with low-grade endometrial stromal sarcoma: A population-based analysis显示文摘Background:Low-grade endometrial stromal sarcoma(LG-ESS)is a rare tumor that lacks a prognostic prediction model.Our study aimed to develop a nomogram to predict overall survival of LG-ESS patients.Methods:A total of 1172 patients confirmed to have LG-ESS between 1988 and 2015 were selected from the Surveillance,Epidemiology and End Results(SEER)database.They were further divided into a training cohort and a validation cohort.The Akaike information criterion was used to select variables for the nomogram.The discrimination and calibration of the nomogram were evaluated using concordance index(C-index),area under time-dependent receiver operating characteristic curve(time-dependent AUC),and calibration plots.The net benefits of the nomogram at different threshold probabilities were quantified and compared with those of the International Federation of Gynecology and Obstetrics(FIGO)criteria-based tumor staging using decision curve analysis(DCA).Net reclassification index(NRI)and integrated discrimination improvement(IDI)were also used to compare the nomogram’s clinical utilitywith that of the FIGO criteria-based tumor staging.The risk stratifications of the nomogram and the FIGO criteria-based tumor staging were compared.Results:Seven variables were selected to establish the nomogram for LG-ESS.The C-index(0.814 for the training cohort and 0.837 for the validation cohort)and the time-dependent AUC(>0.7)indicated satisfactory discriminative ability of the nomogram.The calibration plots showed favorable consistency between the prediction of the nomogram and actual observations in both the training and validation cohorts.The NRI values(training cohort:0.271 for 5-year and 0.433 for 10-year OS prediction;validation cohort:0.310 for 5-year and 0.383 for 10-year OS prediction)and IDI(training cohort:0.146 for 5-year and 0.185 for 10-year OS prediction;validation cohort:0.177 for 5-year and 0.191 for 10-year OS prediction)indicated that the established nomogram performed significantly better than the FIGO criteria-based tumor staging alone(P<0.05).Furthermore,DCA showed that the nomogram was clinically useful and had better discriminative ability to recognize patients at high risk than the FIGO criteria-based tumor staging.Conclusions:A prognostic nomogram was developed and validated to assist clinicians in evaluating prognosis of LG-ESS patients. | Jie Wu Huibo Zhang Lan Li Mengxue Hu Liang Chen Bin Xu Qibin Song | 2020 | Cancer Communications2020，40，7： | 35 |
| 2 | Lattice Boltzmann simulation of fluid flow through coal reservoir's fractal pore structure显示文摘The influences of fractal pore structure in coal reservoir on coalbed methane(CBM) migration were analyzed in detail by coupling theoretical models and numerical methods.Different types of fractals were generated based on the construction thought of the standard Menger Sponge to model the 3D nonlinear coal pore structures.Then a correlation model between the permeability of fractal porous medium and its pore-size-distribution characteristics was derived using the parallel and serial modes and verified by Lattice Boltzmann Method(LBM).Based on the coupled method,porosity(ф),fractal dimension of pore structure(Db),pore size range(rmin,rmax) and other parameters were systematically analyzed for their influences on the permeability(ф) of fractal porous medium.The results indicate that:① the channels connected by pores with the maximum size(rmax) dominate the permeability,approximating in the quadratic law;② the greater the ratio of r max and r min is,the higher is;③ the relationship between D b and follows a negative power law model,and breaks into two segments at the position where Db ≌2.5.Based on the results above,a predicting model of fractal porous medium permeability was proposed,formulated as k=cfrnmax,where C and n(approximately equal to 2) are constants and f is an expression only containing parameters of fractal pore structure.In addition,the equivalence of the new proposed model for porous medium and the Kozeny-Carman model k=Crn was verified at Db =2.0. | JIN Yi SONG HuiBo HU Bin ZHU YiBo ZHENG JunLing | 2013 | Science China Earth Sciences2013，56，9： | 15 |
| 3 | Roles of a sustained activation of NCED3 and the synergistic regulation of ABA biosynthesis and catabolism in ABA signal production in Arabidopsis显示文摘ABA, acting as a stress signal, plays crucial roles in plant resistance to water stress. Because ABA signal production is based on ABA biosynthesis, the regulation of NCED, a key enzyme in the ABA biosynthesis pathway, is normally thought of as the sole factor controlling ABA signal production. Here we demonstrate that ABA catabolism in combination with a synergistic regulation of ABA biosynthesis plays a crucial role in governing ABA signal production. Water stress induced a significant accumulation of ABA, which exhibited different patterns in detached and attached leaves. ABA catabolism followed a temporal trend of exponential decay for both basic and stress ABA, and there was little difference in the catabolic half-lives of basic ABA and stress ABA. Thus, the absolute rate of ABA catabolism, i.e. the amount of ABA catabolized per unit time, increases with increased ABA accumulation. From the dynamic processes of ABA biosynthesis and catabolism, it can be inferred that stress ABA accumulation may be governed by a synergistic regulation of all the steps in the ABA biosynthesis pathway. Moreover, to maintain an elevated level of stress ABA sustained activation of NCED3 should be required. This inference was supported by further findings that the genes encoding major enzymes in the ABA biosynthesis pathway, e.g. NCED3, AAO3 and ABA3 were all activated by water stress, and with ABA accumulation progressing, the expressions of NCED3, AAO3 and ABA3 remained activated. Data on ABA catabolism and gene expression jointly indicate that ABA signal production is controlled by a sustained activation of NCED3 and the synergistic regulation of ABA biosynthesis and catabolism. | REN HuiBo FAN YiJian GAO ZhiHui WEI KaiFa LI GuiFen LIU Jing CHEN Lin LI BingBing HU JianFang JIA WenSuo | 2007 | Chinese Science Bulletin2007，52，4： | 12 |
| 4 | Modulation of Root Signals in Relation to Stomatal Sensitivity to Root-sourced Abscisic Acid in Drought-affected Plants显示文摘到弄干的土壤导致的根信号的有气孔的敏感可以在环境和植物种类之间变化。这是可能的在根信号之中是相互作用和调整的结果。作为一个压力信号, abscisic 酸(骆驼毛的织物) 在根起一个中央作用射击发信号。pH 和水力的信号可以与骆驼毛的织物信号交往并且这样,联合调整有气孔的回答到改变的土壤水地位。pH 本身能被几个因素,在木部的化学组成在之中流修改,包围容器的实时房间起关键作用。除了木部 pH,更多的注意应该对叶 apoplastic pH 的直接调整被给予,因为当没在木部 pH 上有重要效果时,许多化学组成可能强烈修改叶 apoplastic pH。ABA 信号紧张的直接调整可能是更重要的让有气孔的回答的规定玷污比 ABA 信号本身弄干。如果射击弄干的土壤的通讯的一条持续的根在整个植物水平操作,骆驼毛的织物信号被 ABA 分解代谢和先锋的供应也调整到根。更重要地,骆驼毛的织物分解代谢能在 ABA 信号的命运的决心起关键作用并且从而控制采购根的骆驼毛的织物信号的有气孔的行为。 | Huibo Ren Kaifa Wei Wensuo Jia William John Davies Jianhua Zhang | 2007 | Journal of Integrative Plant Biology2007，49，10： | 11 |
| 5 | ROP GTPase-mediated auxin signaling regulates pavement cell interdigitation in Arabidopsis thaliana显示文摘In multicellular plant organs, cell shape formation depends on molecular switches to transduce developmental or environmental signals and to coordinate cell‐to‐cell communication. Plants have a specific subfamily of the Rho GT Pase family, usually called Rho of Plants(ROP), which serve as a critical signal transducer involved in many cellular processes. In the last decade, important advances in the ROP‐mediated regulation of plant cell morphogenesis have been made by using Arabidopsis thaliana leaf and cotyledon pavement cells.Especially, the auxin‐ROP signaling networks have been demonstrated to control interdigitated growth of pavement cells to form jigsaw‐puzzle shapes. Here, we review findings related to the discovery of this novel auxin‐signaling mechanism at the cell surface. This signaling pathway is to a large extent independent of the well‐known Transport Inhibitor Response(TIR)–Auxin Signaling F‐Box(AFB) pathway, and instead requires Auxin Binding Protein 1(ABP1) interaction with the plasma membrane‐localized, transmembrane kinase(TMK) receptor‐like kinase to regulate ROP proteins. Once activated, ROP influences cytoskeletal organization and inhibits endocytosis of the auxin transporter PIN1. The present review focuses on ROP signaling and its self‐organizing feature allowing ROP proteins to serve as a bustling signal decoder and integrator for plant cell morphogenesis. | Deshu Lin Huibo Ren Ying Fu | 2015 | Journal of Integrative Plant Biology2015，57，1： | 9 |
| 6 | Advances in luminescent lanthanide complexes and applications显示文摘Luminescent lanthanide complexes have been widely investigated as light emitting materials in bio-imaging and sensing, solid state lighting and display, anti-fake tags and light conversion films, due to their characterized photophysical properties including large Stokes shift, long lifetime, and sharp emission spectrum, arising from the sensitized f-f transitions. In this review, we summarize the most recent advances in luminescent lanthanide complexes and their applications from 2015 to August 2017 concerning of general concepts to potential applications. We first introduce the basic concept of sensitized luminescence of lanthanide complexes and the strategies used for highly luminescent complexes. Then recent varieties of luminescent lanthanide complexes and their hybrid materials are presented. Finally, applications are discussed in detail. | WEI Chen MA Li WEI HuiBo LIU ZhiWei BIAN ZuQiang HUANG ChunHui | 2018 | Science China(Technological Sciences)2018，61，9： | 8 |
| 7 | Chemical Synthesis Residual Pyrolysis and Combustion: Kinetics and Evolved Gases Investigated by TG-FTIR显示文摘Chemical synthetic residual is one of the solid wastes generated from pharmaceutical industry.The pyrolysis and combustion characteristics of chemical synthesis residual were investigated using a thermogravimetric analyser coupled with Fourier transform infrared spectroscopy(TG-FTIR)in this study.The processes of pyrolysis and combustion can be divided into three stages.The average weight loss rate of pyrolysis process at low temperature was higher than that of combustion.The kinetic parameters of chemical synthesis residual during pyrolysis and combustion were calculated based on the TG results.Acetic acid and 4-aminophenol were the main evolved matter observed in the pyrolysis process.The emission characteristics of combustion at low temperature were similar to that of the pyrolysis,while CO2 was found as the major gaseous product at high temperature.A high temperature about 850°C is needed to make sure the complete combustion of chemical synthesis residual. | FANG Chunqi JIANG Xuguang LV Guojun YAN Jianhua LIN Xuliang SONG Huibo CAO Junjun | 2020 | Journal of Thermal Science2020，29，1： | 3 |
| 8 | Demonstration of ultralow-threshold 2 micrometer microlasers on chip显示文摘We demonstrate ultralow-threshold thulium-doped, as well as thulium-holmium-codoped, microtoroid lasers on silicon chips, operating at the wavelength of around 2 ?m. High quality factor whispering gallery mode(WGM) microtoroid cavities with proper thulium and holmium concentrations are fabricated from the silica sol-gel films. The highly confined WGMs make the microcavity lasers operate with ultralow thresholds, approximately 2.8 ?W and 2.7 ?W for the thulium-doped and the thulium-holmium-codoped microlasers, respectively. | FAN HuiBo JIANG XiaoShun DING Yang XIAO Min | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，11： | 3 |
| 9 | Postconditioning of stellate ganglion block improves intestinal barrier function by inhibiting autophagy in conscious rats following hemorrhagic shock and resuscitation显示文摘To the Editor:Hemorrhagic shock is a critical pathological process characterized by microcirculation dysfunction and hypoperfusion,with severe consequences of cell damage and organ dysfunction.Intestinal barrier dysfunction is a critical link of distant organ injury caused by hemorrhagic shock.Prophylactic treatment with stellate ganglion block(SGB)significantly reduces hemorrhagic shock-induced intestinal barrier damage. | Zhonghua Li Wendi Wang Qi Sun Tingjiao Suo Jiayi Zhai Huibo Du Zhen’ao Zhao Fulong Li Chunyu Niu Zigang Zhao | 2022 | Chinese Medical Journal2022，，8： | 2 |
| 10 | Well-posedness of M/G/1 queueing model with second optional service显示文摘 | ZHAO Huibo Geni Gupur Muyidin Helil | | 0，，： | 1 |
| 11 | Non-Hanan routing显示文摘 | Huibo Hou Jiang Hu Sapatnekar S S | 1999 | Computer-Aided Design of Integrated Circuits and Systems IEEE Transactions on1999，18，4： | 1 |
| 12 | Hormone therapy and Alzheimer disease dementia:new findings from the Cache County Study显示文摘 | SHAO Huibo Breitner JC Whitmer RA | 2012 | Neurology2012，79，18： | 1 |
| 13 | Realizing the highly reversible Zn^(2+)and Na^(+) dual ions storage in high-crystallinity nickel hexacyanoferrate microcubes for aqueous zinc-ion batteries显示文摘Prussian blue analogues(PBAs)with the 3D open framework are regarded as promising cathode candidates for aqueous Zinc ion batteries(ZIBs).Among various PBAs,nickel hexacyanoferrate(NiHCF)has attracted considerable attention because of its high operating voltage and economic merit.However,the cyclability of NiHCF is unsatisfactory due to poor structural stability during Zn^(2+) ions insertion/deinsertion.Moreover,the ion storage mechanism of NiHCF in aqueous electrolytes has not been fully revealed yet.Herein,high-crystallinity NiHCF(HC-NiHCF)microcubes with improved structural stability and larger crystal plane spacing are synthesized.For the first time,highly reversible Zn2+ions and Na+ions co-insertion/extraction are achieved for the HC-NiHCF microcubes in mixed aqueous electrolyte,as evidenced by various observations including two separated discharge plateaus and sequential changes of Na 1s and Zn 2p signals in ex-situ X-ray photoelectron spectroscopy(XPS).As a result,a high specific capacity of 73.9 mAh g^(−1) is obtained for the HC-NiHCF microcubes at 0.1 A g−1,combined with enhanced cycle stability(75%vs.16.4%)over 1000 cycles at 2 A g^(−1).The reversible Zn^(2+) ions and Na+ions co-insertion in HC-NiHCF microcubes reveals a new ion storage mechanism of Ni-based PBAs in aqueous electrolytes. | Kexuan Wang Zhu Xu Heng Li Huibo Wang Mingzheng Ge Jilei Liu Shengwen Li Zekun Hu Mengyu Zhu Yanyan Zhang Yuxin Tang Shi Chen | 2023 | Journal of Materials Science & Technology2023，，33： | 1 |
| 14 | Geochemistry of the late Permian No. 30 coal seam, Zhijin Coalfield of Southwest China: influence of a siliceous low-temperature hydrothermal fluid显示文摘 | Shifeng Dai Dahua Li Deyi Ren Yuegang Tang Longyi Shao Huibo Song | 2004 | Applied Geochemistry2004，，8： | 1 |
| 15 | Analysis of indoor humidity environment in Chinese residential buildings显示文摘 | Huibo Zhang Hiroshi Yoshino | 2010 | Building and Environment2010，，10： | 1 |
| 16 | Comparison between single-mode treatment and multi mode treatment of a coaxial Bragg re sonator for a terahertz cyclotron autoresonance maser osciilator显示文摘 | Xin Qi Zhang Shichang Zhang Huibo | 2010 | J Infrared Milli Terahz Waves2010，31，9： | 1 |
| 17 | Zircon U-Pb Age,Geochemical,and Sr-Nd-Pb-Hf Isotopic Constraints on the Time Frame and Origin of Early Cretaceous Mafic Dykes in the Wuling Mountain Gravity Lineament,South China显示文摘In view of the importance of mafic dyke swarms and their contribution to current scientific problems relating to South China,herein,we present the findings of studies on twenty–five representative mafic dykes cropping out in Hunan Province and Guangxi Zhuang Autonomous Region,within the southern Wuling Mountain gravity lineament,China.These results include new zircon LA-ICP-MS U-Pb age,whole rock geochemical,Sr-Nd-Pb isotopic,and zircon Hf isotopic data for these dykes.The dykes formed between 131.5±1.2 and 121.6±1.1 Ma,and have typical doleritic textures.They fall into the alkaline and shoshonitic series,are enriched in light rare earth elements(LREE),some large ion lithophile elements(LILE;e.g.,Rb,Ba,and Sr),Th,U,and Pb,and are depleted in Nb,Ta,Hf,and Ti.Moreover,the dolerites have high initial 87 Sr/86 Sr ratios(0.7055–0.7057),negativeεNd(t)and zirconεHf(t)values(-14.8 to-11.9,-30.4 to-14.9),and relatively constant initial Pb isotopic ratios(that are EM1-like,16.77–16.94,15.43–15.47,and 36.84–36.92 for 206 Pb/204 Pb,207 Pb/204 Pb,and 208 Pb/204 Pb,respectively).These results indicate that the dykes were likely derived from magma generated through low-degree partial melting(1.0%–10%)of an EM1-like garnet–lherzolite mantle source.The parental magmas fractionated olivine,clinopyroxene,plagioclase,and Ti-bearing phases with negligible crustal contamination,during ascent and dyke emplacement.Several possible models have been proposed to explain the origin of Mesozoic magmatism along the Wuling Mountain gravity lineament.Herein we propose a reasonable model for the origin of these mafic dykes,involving the collision between the paleo-Pacific Plate and South China,which led to subsequent lithospheric extension and asthenosphere upwelling,resulting in partial melting the underlying mantle lithosphere in the Early Cretaceous,to form the parental magmas to the WMGL mafic dykes,as studied. | CHEN Xiaoqing LIU Shen FENG Caixia XU Jingyan ZHAO Huibo FENG Guangying Ian M.COULSON SUN Jinggui FAN Yan | 2021 | Acta Geologica Sinica(English Edition)2021，95，2： | 1 |
| 18 | Defective super-long carbon nanotubes and polypyrrole composite for high-performance supercapacitor electrodes显示文摘 | Yue Hu Yang Zhao Yan Li Hui Li Huibo Shao Liangti Qu | 2012 | Electrochimica Acta2012，，： | 1 |
| 19 | Hormone therapy and Alzheimer disease dementia: New findings from the Cache County Study显示文摘 | Huibo Shao John C.S. Breitner Rachel A. Whitmer Junmin Wang Kathleen Hayden Heidi Wengreen Chris Corcoran JoAnn Tschanz Maria Norton Ron Munger Kathleen Welsh-Bohmer Peter P. Zandi James Anthony Erin Bigler Ron Brookmeyer James Burke Eric Christopher Jane | 2012 | Neurology2012，，18： | 1 |
| 20 | Improving hydrogen pro-duction from cassava starch by combination of dark and photofermentation显示文摘 | Su Huibo Cheng Jun Zhou Junhu | 2009 | International Journal of Hydrogen Energy2009，34，4： | 1 |
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