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| 1 | Evaluation of biological pretreatment with white rot fungi for the enzymatic hydrolysis of bamboo culms 显示文摘 | Zhang Xiaoyu Yu Hongbo Huang Huiyan | 2007 | International Biodeterioration & Biodegradation2007，60，3： | 1 |
| 2 | Thermal stability of nanostructured 13wt% A1203-8wt% Y203-ZrO2 thermal barrier coatings 显示文摘 | Yu Qinghe Zhou Chungen Zhang Huiyan | 2010 | Journal of the European Ceramic Society2010，30，： | 1 |
| 3 | Analysis of Clinicopathologic Features and Prognostic Factors in Hepatoid Adenocarcinoma of the Stomach显示文摘 | Xiaowen Liu Yufan Cheng Weiqi Sheng Hongfen Lu Xiaoli Xu Yu Xu Ziwen Long Huiyan Zhu Yanong Wang | 2010 | The American Journal of Surgical Pathology2010，，10： | 1 |
| 4 | Highly Efficient Image Stitching Based on Energy Map显示文摘 | Yu Tang Huiyan Jiang | 2009 | IEEE CISP''092009，，： | 1 |
| 5 | Analysis of Phase Coexistence in Fe2O3‐Doped 0.2PZN–0.8PZT Ferroelectric Ceramics by Raman Scattering Spectra显示文摘 | Man‐KangZhu Peng‐XianLu Yu‐DongHou Xue‐MeiSong HaoWang HuiYan | 2006 | Journal of the American Ceramic Society2006，，12： | 1 |
| 6 | A broadly neutralizing human monoclonal antibody against the hemagglutinin of avian influenza virus H7N9显示文摘Background:The new emerging avian influenza A H7N9 virus,causing severe human infection with a mortality rate of around 41%.This study aims to provide a novel treatment option for the prevention and control of H7N9.Methods:H7 hemagglutinin(HA)-specific B cells were isolated from peripheral blood plasma cells of the patients previously infected by H7N9 in Jiangsu Province,China.The human monoclonal antibodies(mAbs)were generated by amplification and cloning of these HA-specific B cells.First,all human mAbs were screened for binding activity by enzyme-linked immunosorbent assay.Then,those mAbs,exhibiting potent affinity to recognize H7 HAs were further evaluated by hemagglutination-inhibiting(HAI)and microneutralizationin vitro assays.Finally,the lead mAb candidate was selected and tested against the lethal challenge of the H7N9 virus using murine models.Results:The mAb 6-137 was able to recognize a panel of H7 HAs with high affinity but not HA of other subtypes,including H1N1 and H3N2.The mAb 6-137 can efficiently inhibit the HA activity in the inactivated H7N9 virus and neutralize 100 tissue culture infectious dose 50(TCID_(50))of H7N9 virus(influenza A/Nanjing/1/2013)invitro,with neutralizing activity as low as 78 ng/mL.In addition,the mAb 6-137 protected the mice against the lethal challenge of H7N9 prophylactically and therapeutically.Conclusion:The mAb 6-137 could be an effective antibody as a prophylactic or therapeutic biological treatment for the H7N9 exposure or infection. | Jingxin Li Li Zhang Linlin Bao Yuxiao Wang Lin Qiu Jialei Hu Rong Tang Huiyan Yu Jun Shan Yan Li Chuan Qin Fengcai Zhu | 2022 | Chinese Medical Journal2022，，7： | 1 |
| 7 | Key-insulated aggregate signature显示文摘为了最小化损坏,在总数签名由关键暴露引起了,一个绝缘钥匙的总数签名计划在这份报纸被建议。我们给定义和绝缘钥匙的总数签名的安全模型。我们也构造满足我们的定义的一个具体绝缘钥匙的总数签名计划。我们的计划有有效确认和短签名长度的性质。我们在计算 Diffie-Hellman 假设下面在随机的神谕模型证明我们的计划的安全。 | Huiyan ZHAO Jia YU Shaoxia DUAN Xiangguo CHENG Rong HAO | 2014 | Frontiers of Computer Science2014，8，5： | 1 |
| 8 | Dietary Epimedium extract supplementation improves intestinal functions and alters gut microbiota in broilers显示文摘Background Growth-promoting antibiotics have been banned by law in the livestock and poultry breeding industry in many countries.Various alternatives to antibiotics have been investigated for using in livestock.Epimedium(EM)is an herb rich in flavonoids that has many beneficial effects on animals.Therefore,this study was planned to explore the potential of EM as a new alternative antibiotic product in animal feed.Methods A total of 7201-day-old male broilers(Arbor Acres Plus)were randomly divided into six groups and fed basal diet(normal control;NC),basal diet supplemented with antibiotic(75 mg/kg chlortetracycline;CTC),and basal diet supplemented with 100,200,400 or 800 mg/kg EM extract for 6 weeks(EM100,EM200,EM400 and EM800 groups).The growth performance at weeks 3 and 6 was measured.Serum,intestinal tissue and feces were collected to assay for antioxidant indexes,intestinal permeability,lactic acid and short-chain fatty acids(SCFAs)profiles,microbial composition,and expression of intestinal barrier genes.Results The average daily feed intake in CTC group at 1-21 d was significantly higher than that in the NC group,and had no statistical difference with EM groups.Compared with NC group,average daily gain in CTC and EM200 groups increased significantly at 1-21 and 1-42 d.Compared with NC group,EM200 and EM400 groups had significantly decreased levels of lipopolysaccharide and D-lactic acid in serum throughout the study.The concentrations of lactic acid,acetic acid,propionic acid,butyric acid and SCFAs in feces of birds fed 200 mg/kg EM diet were significantly higher than those fed chlortetracycline.The dietary supplementation of chlortetracycline and 200 mg/kg EM significantly increased ileal expression of SOD1,Claudin-1 and ZO-1 genes.Dietary supplemented with 200 mg/kg EM increased the relative abundances of g_NK4A214_group and Lactobacillus in the jejunal,while the relative abundances of Microbacterium,Kitasatospora,Bacteroides in the jejunal and Gallibacterium in the ileum decreased.Conclusion Supplementation with 200 mg/kg EM extract improved the composition of intestinal microbiota by regulating the core bacterial genus Lactobacillus,and increased the concentration of beneficial metabolites lactic acid and SCFAs in the flora,thereby improving the antioxidant capacity and intestinal permeability,enhancing the function of tight junction proteins.These beneficial effects improved the growth performance of broilers. | Jiaqi Zhang Haitao Yu Huiyan Zhang Qingyu Zhao Wei Si Yuchang Qin Junmin Zhang | 2023 | Journal of Animal Science and Biotechnology2023，14，4： | 1 |
| 9 | Effect of sodium ozagrel on the activity of rat CYP2D6显示文摘 | Hong Wu Weijiang Yu Lijun Huang Jing Wang Xiaobo Tang Wei Yang Yan Liu Huiyan Yu Daling Zhu | 2007 | European Journal of Pharmacology2007，，1： | 1 |
| 10 | Carotenoid enrichment in eggs:From biochemistry perspective显示文摘The emergence of safe and functional eggs for consumer acceptance has gained focus.The production of carotenoid-enriched eggs has received attention due to its multifunctional biological properties.Nutritional modification of laying hens’diet can be a strategy to produce such eggs.This review presents the chemistry of carotenoids in nature and eggs,the accumulation process of carotenoids into eggs,and the functions of carotenoids in eggs.Our findings showed that carotenoids can be deposited into the egg and contribute to improving its nutritive value.The biosynthesis,chemical structure,and metabolism pathways of carotenoids lead to the deposition of carotenoids into eggs in their original or metabolized forms.Also,some factors modulate the efficiency of carotenoids in fowls before accumulation into eggs.Carotenoid-enriched eggs may be promising,ensuring the availability of highly nutritive eggs.However,further studies are still needed to comprehend the full metabolism process and the extensive functions of carotenoids in eggs. | Dieudonne M.Dansou Huiyan Zhang Yanan Yu Hao Wang Chaohua Tang Qingyu Zhao Yuchang Qin Junmin Zhang | 2023 | Animal Nutrition2023，，3： | 0 |
| 11 | Research on Reimbursement Management of Innovative Drugs Abroad and Its Enlightenment to China显示文摘Objective To analyze the reimbursement policies of innovative drugs in some developed countries,and to provide reference for future reimbursement management in China.Methods Literature research method was used to study the policies related to the reimbursement management of innovative drugs in Germany,France and Japan,and their successful experience was summarized.Results and Conclusion China should establish an open and transparent value evaluation standard to improve the medical insurance reimbursement management of innovative drugs.Besides,the value of innovative drugs should be taken as an important basis for reimbursement decisions,and an independent third-party value evaluation agency must be established. | Yu Hanshuang Huang Xianqin Wang Huiyan Sun Lihua | 2024 | Asian Journal of Social Pharmacy2024，19，1： | 0 |
| 12 | Energy-Efficient Deployment of Water Quality Sensor Networks显示文摘Water quality sensor networks are promising tools for the exploration of oceans.Some key areas need to be monitored effectively.Water quality sensors are deployed randomly or uniformly,however,and understanding how to deploy sensor nodes reasonably and realize effective monitoring of key areas on the basis of monitoring the whole area is an urgent problem to be solved.Additionally,energy is limited in water quality sensor networks.When moving sensor nodes,we should extend the life cycle of the sensor networks as much as possible.In this study,sensor nodes in non-key monitored areas are moved to key areas.First,we used the concentric circle method to determine the mobile sensor nodes and the target locations.Then,we determined the relationship between the mobile sensor nodes and the target locations according to the energy matrix.Finally,we calculated the shortest moving path according to the Floyd algorithm,which realizes the redeployment of the key monitored area.The simulation results showed that,compared with the method of direct movement,the proposed method can effectively reduce the energy consumption and save the network adjustment time based on the effective coverage of key areas. | Qian Sun Zhiping Shen Jinglin Liang Xiaoyi Wang Jiping Xu Li Wang Huiyan Zhang Jiabin Yu Ning Cao Ruichao Wang | 2021 | Computers, Materials & Continua2021，，9： | 0 |
| 13 | Precise Positions of Triton in 2010–2014 based on Gaia-DR2显示文摘With unique orbital and physical characteristics,Triton is a very important target because it may contain information of the origin and evolution of the solar system.Besides space explorations,ground-based observations over long time also play a key role on research of Triton.High-precision positions of Triton obtained from ground telescopes are of great significance for studying its orbital evolution and the physical properties of Neptune.As a long-term observational target,Triton has been observed by the 1.56 m telescope of Shanghai Astronomical Observatory since 1996.In this paper,based on our AAPPDI software and with Gaia DR2 as the reference catalog,604 positions of Triton during 2010–2014 are calculated,with standard errors of 19–88 mas.A comparison between our results and the ephemeris(DE431+nep096)is also given. | Huiyan Zhang Yong Yu Dan Yan Kai Tang Rongchuan Qiao | 2022 | Research in Astronomy and Astrophysics2022，22，3： | 0 |
| 14 | Network Invulnerability Enhancement Algorithm Based on WSN Closeness Centrality显示文摘Wireless Sensor Network(WSN)is an important part of the Internet of Things(IoT),which are used for information exchange and communication between smart objects.In practical applications,WSN lifecycle can be influenced by the unbalanced distribution of node centrality and excessive energy consumption,etc.In order to overcome these problems,a heterogeneous wireless sensor network model with small world characteristics is constructed to balance the centrality and enhance the invulnerability of the network.Also,a new WSN centrality measurement method and a new invulnerability measurement model are proposed based on the WSN data transmission characteristics.Simulation results show that the life cycle and data transmission volume of the network can be improved with a lower network construction cost,and the invulnerability of the network is effectively enhanced. | Qian Sun Fengbo Yang Xiaoyi Wang Jing Li Jiping Xu Huiyan Zhang Li Wang Jiabin Yu Xiao Peng Ruichao Wang | 2022 | Computers, Materials & Continua2022，，11： | 0 |
| 15 | Optimal Deployment of Heterogeneous Nodes to Enhance Network Invulnerability显示文摘Wireless sensor networks(WSN)can be used in many fields.In wireless sensor networks,sensor nodes transmit data in multi hop mode.The large number of hops required by data transmission will lead to unbalanced energy consumption and large data transmission delay of the whole network,which greatly affects the invulnerability of the network.Therefore,an optimal deployment of heterogeneous nodes(ODHN)algorithm is proposed to enhance the invulnerability of the wireless sensor networks.The algorithm combines the advantages of DEEC(design of distributed energy efficient clustering)clustering algorithm and BAS(beetle antenna search)optimization algorithm to find the globally optimal deployment locations of heterogeneous nodes.Then,establish a shortcut to communicate with sink nodes through heterogeneous nodes.Besides,considering the practical deployment operation,we set the threshold of the mobile location of heterogeneous nodes,which greatly simplifies the deployment difficulty.Simulation results show that compared with traditional routing protocols,the proposed algorithm can make the network load more evenly,and effectively improve energy-utilization and the fault tolerance of the whole network,which can greatly improve the invulnerability of the wireless sensor networks. | Qian Sun Fengbo Yang Xiaoyi Wang Jiping Xu Huiyan Zhang Li Wang Jiabin Yu Xiao Peng Ruichao Wang | 2022 | Computers, Materials & Continua2022，，11： | 0 |
| 16 | Foreign Experience and Enlightenment of Reimbursement Management of Multi-indication Drugs显示文摘Objective To provide reference for China’s medical insurance reimbursement plan of multi-indication drugs.Methods By referring to relevant foreign literature,the implementation process and conditions of different reimbursement management modes of multi-indication drugs were analyzed to provide suggestions for reimbursement of multi-indication drugs in China.Results and Conclusion It is suggested to further explore the suitable conditions and select the corresponding mode in China.Payment standards should be set according to value pricing and budget impact analysis.Besides,data collection and analysis mechanism must be improved.Lastly,reward and punishment mechanism can be adopted to improve management efficiency. | Wang Huiyan Yu Hanshuang Sun Lihua | 2023 | Asian Journal of Social Pharmacy2023，18，4： | 0 |
| 17 | Soil phosphorus fractions and their availability over natural succession from clear-cut of a mixed broadleaved and Korean pine forest in northeast China显示文摘To assess phosphorus(P)status of forest soil under naturally restored vegetation,P fractions in the 10-cm soil layer were quantified at different successional stages on the clear-cut site of mixed broadleaved and Korean pine forest.Four communities of shrub,softwood broad-leaved forest,softwood and hardwood broad-leaved forest,and hardwood broad-leaved forest represented different successional stages.A soil sample from a primary broad-leaved and Korean pine stand was the control.A sequential P fractionation scheme extracted empirically defined pools of P and path analysis used to partition the direct and indirect contribution of soil P fractions to available P.The results show that available P increased significantly with long-term succession,while both sodium bicarbonate-extractable P(NaHCO_(3)-P)and sodium hydroxide-extractable P(NaOHP)fractions were reduced in early successional stages and increased in late stages.Compared to the primary forest,concentrations of P fractions in the four stages significantly decreased except for HCl-P,indicating that soil P supplements over the long-term did not return to primary forest levels.The results of related analysis also showed that NaHCO_(3)-P_(i)levels were significantly related to available phosphorus.According to the path analysis coefficient,NaHCO_(3)-P_(i)exhibited the highest effect on available P among eight P fractions;the indirect effects of other P fractions via NaHCO_(3)-P_(i)were larger than those with other P fractions.Overall,this study suggests that soil P bioavailability gradually improved during natural vegetation restoration on clear-cut sites mainly through the increase of NaHCO_(3)-P,where phosphorous is immediately available,and subsequently available phosphorus Na OH-P. | Peng Yu Xin Zhang Huiyan Gu Jianping Pan Xiangwei Chen | 2022 | Journal of Forestry Research2022，33，1： | 0 |
| 18 | Expression profiles of genes regulated by BplMYB46 in Betula platyphylla显示文摘The transcription factor BplMYB46 has been identified as a regulator of abiotic stress responses and promoter of secondary wall deposition in Betula platyphylla.To investigate the downstream targets of BplMYB46,the expression profiles of genes in stems from BplMYB46-overexpressing(OE)and BplMYB46-silencing(SE)plants were studied.In OE stems,952 genes were upregulated,and 1469 were downregulated in comparison to SE stems.In a KEGG pathway enrichment analysis of differentially expressed genes(DEGs),1387 differentially expressed genes were annotated for 117 metabolic pathways.DEGs were abundant for metabolic pathway,secondary metabolite biosynthesis,plant hormone signal transduction,phenylpropanoid and flavonoid biosynthesis.DEGs were implicated lignin or cellulose biosynthesis,cell wall modification,xylem development,disease resistance,stress responses,and anthocyanin biosynthesis.These results suggested that BplMYB46 regulates cell wall development and stress resistance by affecting the expression of these genes.Our study further elucidates the mechanism by which BplMYB46 mediates abiotic stress responses and secondary cell wall biosynthesis in birch. | Huiyan Guo Chunrui Zhang Yanmin Wang Yiming Zhang Yu Zhang Yucheng Wang Chao Wang | 2019 | Journal of Forestry Research2019，30，6： | 0 |
| 19 | DNA methylation markers in the diagnosis and prognosis of common leukemias显示文摘The ability to identify a specific type of leukemia using minimally invasive biopsies holds great promise to improve the diagnosis,treatment selection,and prognosis prediction of patients.Using genome-wide methylation profiling and machine learning methods,we investigated the utility of CpG methylation status to differentiate blood from patients with acute lymphocytic leukemia(ALL)or acute myelogenous leukemia(AML)from normal blood.We established a CpG methylation panel that can distinguish ALL and AML blood from normal blood as well as ALL blood from AML blood with high sensitivity and specificity.We then developed a methylation-based survival classifier with 23 CpGs for ALL and 20 CpGs for AML that could successfully divide patients into high-risk and low-risk groups,with significant differences in clinical outcome in each leukemia type.Together,these findings demonstrate that methylation profiles can be highly sensitive and specific in the accurate diagnosis of ALL and AML,with implications for the prediction of prognosis and treatment selection. | Hua Jiang Zhiying Ou Yingyi He Meixing Yu Shaoqing Wu Gen Li Jie Zhu Ru Zhang Jiayi Wang Lianghong Zheng Xiaohong Zhang Wenge Hao Liya He Xiaoqiong Gu Qingli Quan Edward Zhang Huiyan Luo Wei Wei Zhihuan Li Guangxi Zang Charlotte Zhang Tina Poon Daniel Zhang Ian Ziyar Run-ze Zhang Oulan Li Linhai Cheng Taylor Shimizu Xinping Cui Jian-kang Zhu Xin Sun Kang Zhang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 0 |
| 20 | Coverage Control for Underwater Sensor Networks Based on Residual Energy Probability显示文摘Underwater sensor networks have important application value in the fields of water environment data collection,marine environment monitoring and so on.It has some characteristics such as low available bandwidth,large propagation delays and limited energy,which bring new challenges to the current researches.The research on coverage control of underwater sensor networks is the basis of other related researches.A good sensor node coverage control method can effectively improve the quality of water environment monitoring.Aiming at the problem of high dynamics and uncertainty of monitoring targets,the random events level are divided into serious events and general events.The sensors are set to sense different levels of events and make different responses.Then,an event-driven optimization algorithm for determining sensor target location based on self-organization map is proposed.Aiming at the problem of limited energy of underwater sensor nodes,considering the moving distance,coverage redundancy and residual energy of sensor nodes,an underwater sensor movement control algorithm based on residual energy probability is proposed.The simulation results show that compared with the simple movement algorithm,the proposed algorithm can effectively improve the coverage and life cycle of the sensor networks,and realize real-time monitoring of the water environment. | Jinglin Liang Qian Sun Xiaoyi Wang Jiping Xu Huiyan Zhang Li Wang Jiabin Yu Jing Li Ruichao Wang | 2022 | Computers, Materials & Continua2022，，12： | 0 |
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