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| 1 | Retrospective analysis of extra-gastrointestinal stromal tumors显示文摘AIM:To investigate the clinicopathologic features of patients with extra-gastrointestinal stromal tumors(EGISTs)in South Korea.METHODS:A total of 51 patients with an EGIST were identified.The clinicopathologic features,including sex,age,location,tumor size,histology,mitotic rate,immunohistochemical features,genetic status and survival data,were analyzed.RESULTS:The median age was 55 years(range:29-80years),and male:female ratio was 1:1.04.The most common site was in the mesentery(n=15)followed by the retroperitoneum(n=13)and omentum(n=8).The median tumor size was 9.0 cm(range:2.6-30.0cm)and the median mitotic rate was 5.0/50HPF.(1/50-185/50).KIT was analyzed in 16,which revealed 10cases with wild-type KIT and 6 cases with an exon 11mutation.Among 51 patients,31 patients had undergone surgery,and 10 had unresectable disease and had taken palliative imatinib,which resulted in 22.7 mo of progression-free survival.Of the patients who had undergone surgery,18 did not take adjuvant imatinib,and 8 of these were categorized as'high risk'according to the risk criteria.However,the relapse-free survival was not different(P=0.157)between two groups.CONCLUSION:Because the biologic behaviors of GISTs differ according to the location of the tumor,a more stratified strategy is required for managing EGISTs including incorporation of molecular features. | Jun Ho Yi Byeong-Bae Park Jung Hun Kang In Gyu Hwang Dong Bok Shin Sun Jin Sym Hee Kyung Ahn Soon Il Lee Do Hyoung Lim Keon Woo Park Young-Woong Won Sung Hee Lim Se Hoon Park | 2015 | World Journal of Gastroenterology2015，21，6： | 9 |
| 2 | Efficacy of Pegylated Interferon Monotherapy versus Sequential Therapy of Entecavir and Pegylated Interferon in Hepatitis B e Antigen-Positive Hepatitis B Patients: A Randomized, Multicenter, Phase IIIb Open-Label Study (POTENT Study)显示文摘 | Dae Won Jun Sang Bong Ahn Tae Yeob Kim Joo Hyun Sohn Sang Gyune Kim Se Whan Lee Byung Ho Kim Dong Joon Kim Ja Kyung Kim Hyoung Su Kim Seong Gyu Hwang Won Choong Choi Won Young Tak Heon Ju Lee Ki Tae Yoon Byung Cheol Yun Sung Wook Lee Soon Koo Baik Seung Ha Park Ji Won Park Sol Ji Park Ji Sung Lee | 2018 | Chinese Medical Journal2018，，14： | 5 |
| 3 | Cryptogenic multifocal ulcerous stenosing enteritis: Radiologic features and clinical behavior显示文摘AIM To investigate the characteristic radiologic findings of cryptogenic multifocal ulcerous stenosing enteritis(CMUSE) which can be differentiated from other similar bowel disease and to assess their clinical behavior.METHODS Twenty pathologically and clinically confirmed CMUSE patients(males:females = 8:12; mean age: 40.4 years) between March 2002 and August 2015 from seven academic centers in South Korea were retrospectively reviewed. We evaluated small bowel series(SBS; n = 25), computed tomography(CT) enterography(n = 21), magnetic resonance(MR) enterography(n = 2), and abdominopelvic CT(n = 18) images, focusing on enteric and perienteric manifestations. Any change in radiologic features during followup period was recorded. We evaluated clinical data including presenting symptoms, laboratory finding and presence of relapse from electronic medical records. Histopathologic findings were also evaluated. RESULTS The main symptoms were abdominal pain(n = 12) and anemia(n = 10). All patients showed small bowel strictures(n = 52, mean: 2.6 per patient) on initial CT/MR, located in the ileum(n = 47) or jejunum(n = 5). Strictures showed short-length(mean: 10.44 mm) and circumferential bowel wall thickening(mean: 5.56 mm) with layered enhancement(n = 48) that were also noted on initial SBS(n = 36) with shallow ulcers(n = 10). Some ulcerative lesions or wall thickening progressed into strictures on follow-up SBS/CT, and some strictures revealed recurrent ulceration on followup SBS. There were no penetrating disease features like fistula or abscess and no gastrointestinal tract involvement except the small bowel. Nine patients experienced disease recurrence(median relapse-free period: 32 mo) even post-operatively. Histopathologic features of surgically resected specimens were characterized as multiple superficial ulcerations confined to mucosa or submucosa and multiple strictures.CONCLUSION Under characteristic radiologic findings with multiple short-segmental strictures and/or shallow ulcers of the small intestine, CMUSE should be considered when assessing patients with recurrent abdominal pain and anemia. | Jiyoung Hwang Jin Sil Kim Ah Young Kim Joon Seok Lim Se Hyung Kim Min Ju Kim Mi Sung Kim Kyoung Doo Song Ji Young Woo | 2017 | World Journal of Gastroenterology2017，23，25： | 4 |
| 4 | 建筑物在城市更新中的角色显示文摘随着气候变化越来越受关注,环境恶化的情况越来越严重,加上能源安全和主权之间有著急剧动荡的关系,碳排放和节能减排已经成为大多数国家决策中的首要问题之一。
许多国家继续将碳减排作为全国性的目标,其目的在于减少大气中的碳含量,从而缓减其可能造成的灾难。这种渗透效应包括能源生产、传输以及从小至家用电器,大至汽车,再到巨大的建筑物在内能源消耗装置的设计和使用的法律法规。 | 郑世有 Iris Se Young Hwang | 2012 | 世界建筑导报2012，，2： | 2 |
| 5 | Factors Predictive of Adverse Events Following Endoscopic Papillary Large Balloon Dilation: Results from a Multicenter Series显示文摘 | Soo Jung Park Jin Hong Kim Jae Chul Hwang Ho Gak Kim Don Haeng Lee Seok Jeong Sang-Woo Cha Young Deok Cho Hong Ja Kim Jong Hyeok Kim Jong Ho Moon Sang-Heum Park Takao Itoi Hiroyuki Isayama Hirofumi Kogure Se Joon Lee Kyo Tae Jung Hye Sun Lee Todd H. Baron | 2013 | Digestive Diseases and Sciences2013，，4： | 2 |
| 6 | Weekly docetaxel and gemcitabine in previously treated metastatic esophageal squamous cell carcinoma显示文摘AIM: To assess the efficacy and safety of weekly docetaxel plus a fixed-dose rate(FDR) of gemcitabine in metastatic esophageal squamous cell carcinoma(SCC).METHODS: A multi-center, open-label, prospective phase Ⅱ study was designed.Thirty-three esophageal SCC patients with documented progression after fluoropyrimidine/platinum-based first-line chemotherapy were enrolled and treated with docetaxel 35 mg/m2 and gemcitabine 1000 mg/m2 iv at a FDR(10 mg/m2 per minute) on days 1 and 8.Treatment was repeatedevery twenty-one days until disease progression, unacceptable toxicity, or consent withdrawal.The primary endpoint was response rate(RR), and secondary endpoints were safety, progression-free survival(PFS) and overall survival(OS).RESULTS: Combination of weekly docetaxel and FDR gemcitabine was well tolerated: the most common treatment-related adverse events were anemia(97%), fatigue(64%) and neutropenia(55%).One patient with multiple lung and lymph node metastases died of respiratory failure after receiving four cycles of chemotherapy, and the possibility of drug-induced pneumonitis could not be completely excluded.Disease control(objective response plus stable disease) in the ITT population was achieved in 88% of patients, and the overall RR was 30%(95%CI: 15%-46%).The median PFS and OS were 4.0(95%CI: 3.4-4.6) and 8.8 mo(95%CI: 7.8-9.8 mo), respectively.CONCLUSION: A combination of weekly docetaxel and FDR gemcitabine showed promising antitumor activity and tolerability in previously treated, metastatic esophageal SCC. | Min-Young Lee Ki Sun Jung Hae Su Kim Ji Yun Lee Sung Hee Lim Moonjin Kim Hyun Ae Jung Sung Min Kim Jong Mu Sun Myung-Ju Ahn Jeeyun Lee Se Hoon Park Seong Yoon Yi In Gyu Hwang Sang-Cheol Lee Hee Kyung Ahn Do Hyoung Lim Soon Il Lee Keon Woo Park | 2015 | World Journal of Gastroenterology2015，21，14： | 2 |
| 7 | Clinical features and outcome of solid pseudopapillary neoplasm:differences between adults and children 显示文摘 | Lee SE Jang JY Hwang DW | 2008 | Arch Surg2008，143，12： | 1 |
| 8 | GLQ223:an inhibitor of human immunodeficiency virus replication in acutely and chronically infected cells of lymphocyte and mononuclear phagocyte lineage 显示文摘 | Hwang KM Caldwell SE | 1989 | Proc Natl Acad Sci U S A1989，86，8： | 1 |
| 9 | Clinical features and outcome of solid pseudopapillary neoplasm:differences between adults and children显示文摘 | Lee SE Jang JY Hwang DW | 2008 | Arch Surg2008，143，12： | 1 |
| 10 | Light-weight RFID device interface for controlling RFID tag memory access显示文摘 | Se W O Bang H Hwang J G | 2010 | ICACT Feb2010，，710： | 1 |
| 11 | GLQ223 : an inhibitor of human immuno-deficiency virus replication in acutely and chronical- ly infected cells of lymphocyte and mononuclear phagocyte lineage显示文摘 | MeGrath MS Hwang KM Caldwell SE | 1989 | Prnc Natl Acad Sci U S A1989，86，8： | 1 |
| 12 | Deregulated expression of microRNA-221 with the potential for prognostic biomarkers in surgically resected hepatocellular carcinoma显示文摘 | Sun Och Yoon Sung-Min Chun Eun Hee Han Jene Choi Se Jin Jang Seung A Koh Shin Hwang Eunsil Yu | 2011 | Human Pathology2011，，10： | 1 |
| 13 | Denonvilliers' fascia revisited显示文摘 | Kim JH Kinugasa Y Hwang SE | 2015 | Surg Radiol Anat2015，37，2： | 1 |
| 14 | Radiologic correlates of symp- tom-based diagnostic criteria for chronic rhinosinusitis显示文摘 | Hwang P Irwin S Griest SE | 2003 | Otolaryn- gol Head Neck Surg2003，128，4： | 1 |
| 15 | Subconjunctivally injected,liposome-encapsulated streptokinase enhances the absorption rate of subconjunctival hemorrhages in rabbits显示文摘 | Baek SH Park SJ Jin SE Kim JK Kim CK Hwang JM | | 0，，03： | 1 |
| 16 | Screening of medicinal plant extracts for antioxidant activity显示文摘 | LEE SE HWANG HJ HA JS | 2003 | Life Sci2003，73，6： | 1 |
| 17 | Neuropathology and cellular pathogenesis of spinoce- rebellar ataxia type 12显示文摘 | O'Hearn EE Hwang HS Holmes SE | 2015 | Mov Disord2015，30，13： | 1 |
| 18 | GLQ223:an inhibitor of human immunodeficiency virus replication in acutely and chronically infected cells of lymphocyte and mononuclear phagocyte lineage显示文摘 | McGrath MS Hwang KM Caldwell SE | 1989 | Proc Natl Acad Sci USA1989，86，8： | 1 |
| 19 | F18-fluorodeoxyglucose- positron emission tomography for diagnosis of pelvic tuberculosis mimicking peritoneal careinomatosis 显示文摘 | Hwang JH Kim SE Lee JK | 2009 | Int J Gynaeeol Obstet2009，104，3： | 1 |
| 20 | Radio frequency ablation of small renal tumors:intermediate results显示文摘 | Hwang JJ Walther MM Pautler SE | 2004 | J Urol2004，171，5： | 1 |
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