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| 1 | Experimental obstructive jaundice alters claudin-4 expression in intestinal mucosa: Effect of bombesin and neurotensin显示文摘瞄准:调查试验性的妨碍的黄疸和外长的 bombesin 和 neurotensin (NT )(BBS ) 的影响紧密的连接(TJ ) 的表示上的管理在老鼠的肠上皮的蛋白质 claudin-4。方法:四十只男 Wistar 老鼠随机被划分成五个组:我 = 控制, II = 假冒操作, III = 胆汁管结扎(BDL ) , IV = BDL+BBS (30 microg/kg 每 d ) , V = BDL+NT (300 microg/kg 每 d ) 。在 d 的实验的结束 10,内毒素在门和大动脉的血被测量。终端回肠的织物节组织学地被检验并且免疫组织化学地为在肠上皮的 claudin-4 表示的评估。结果:妨碍的黄疸导致了重要的门和大动脉的 endotoxemia 表明的肠的障碍失败。Claudin-4 表示显著地被增加在上面在 jaundiced 老鼠的第三根绒毛并且一起来它的侧面的分发的规定被注意。BBS 或 NT 的管理恢复了 claudin-4 表示到控制状态并且显著地减少了门和大动脉的 endotoxemia。结论:在肠上皮的试验性的妨碍的黄疸增加 claudin-4 表示,它可以是贡献粘膜障碍的混乱的一个关键因素。毁坏规章的肽 BBS, NT 能阻止这扇改变和还原剂门和全身的 endotoxemia。 | Stelios F Assimakopoulos Constantine E Vagianos Aristides S Charonis Ilias H Alexandris Iris Spiliopoulou Konstantinos C Thomopoulos Vassiliki N Nikolopoulou Chrisoula D Scopa | 2006 | World Journal of Gastroenterology2006,12,21: | 21 |
| 2 | 高强度粉末锻造连杆的研究显示文摘粉末锻造连杆由于具有重量轻、加工量少、强度高、质量一致性好的特点,在全球范围内已被广泛应用于现代高性能汽油机和柴油机。针对内燃机性能不断强化的需求,Metaldyne公司开发了一系列新的粉末配方,详细阐述粉末配方对材料机械强度以及对成型连杆强度的影响。与传统的锻造连杆的强度与失效模态进行了全面的比较,研究结果表明新粉末配方具有更优的机械强度特性、更高的连杆强度及更优的连杆成型质量一致性。 | Edmond Ilia George Lanni 辛军 Ryan Yan Edwin Zung | 2008 | 内燃机学报2008,26,5: | 12 |
| 3 | Role of IL-10 in the progression of kidney disease显示文摘Interleukin-10(IL-10), a cytokine with anti-inflammatory and immunomodulatory functions, regulates the biology of B and T cells. The present review describes the role of IL-10 in normal renal physiology, during acute kidney injury and in the development of chronic renal failure. We further discuss IL-10-induced cellular and molecular pathways and their link to the progression of kidney injury. | Inna Sinuani Ilia Beberashvili Zhan Averbukh Judith Sandbank | 2013 | World Journal of Transplantation2013,3,4: | 11 |
| 4 | Evidence for the role of gastric mucosa at the secretion of soluble triggering receptor expressed on myeloid cells(strem-1) in peptic ulcer disease显示文摘AIM: To investigate the role of gastric mucosa at the secretion of sTREM-1 in peptic ulcer. METHODS: Seventy two patients were enrolled; 35 with duodenal, 21 with gastric ulcer and 16 with chronic gastritis. Patients were endoscoped and gastric juice was aspirated. Patients with duodenal and gastric ulcer underwent a second endoscopy post-treatment. Biopsies were incubated in the absence/presence of endotoxins or gastric juice. Supernatants were collected and sTREM-1 and TNFα were measured by enzyme immunoabsorbent assays. Scoring of gastritis was performed before and after treatment according to updated Sydney score. RESULTS: Patients with duodenal and gastric ulcer and those with chronic gastritis had similar scores of gastritis. sTREM-1 was higher in supernatants of tissue samples of H pylori-positive than of H pylori-negative patients with gastric ulcer. Median (± SE) sTREM-1 was found increased in supernatants of patients with gastric ulcer before treatment (203.21 ± 88.91 pg/1000 cells) compared to supernatants either from the same patients post-treatment (8.23 ± 5.79 pg/1000 cells) or from patients with chronic gastritis (6.21 ± 0.71 pg/1000 cells) (P < 0.001 and < 0.001, respectively). Similar differences for sTREM-1 were recorded among LPS-stimulated tissue samples of patients (P = 0.001). Similar differences were not found for TNFα. Positive correlations were found between sTREM-1 of supernatants from patients withboth duodenal and gastric ulcer before treatment and the degree of infiltration of neutrophils and monocytes. CONCLUSION: sTREM-1 secreted by the gastric mucosa is an independent mechanism connected to the pathogenesis of peptic ulcer. sTREM-1 was released at the presence of H pylori from the inflamed gastric mucosa in the field of gastric ulcer. | Vassilios Koussoulas Spyridon Vassiliou Ekaterini Spyridaki Maria Demonakou Ilia Vaki Charalambos Barbatzas Helen Giamarellou Evangelos J Giamarellos-Bourboulis | 2007 | World Journal of Gastroenterology2007,13,34: | 11 |
| 5 | Predicting anatomical results of surgical treatment of idiopathic macular hole显示文摘AIM: To determine the parameters most informative in predicting the anatomical results of surgical treatment of idiopathic full-thickness macular hole(IMH).·METHODS: One hundred and sixty-two consecutive patients(170 eyes) after primary operation for IMH were enrolled. Outcomes were classified as anatomical success when both IMH closure and restoration of the outer retinal structure were achieved. 'Prospective' group included 108 patients(115 eyes) followed with optical coherence tomography(OCT) and microperimetry for 1y after surgery. Potential prognostic criteria, except microperimetry data, were tested in 'retrospective' group(54 patients, 55 eyes). Prognostic value of each parameter was determined using receiver operating characteristic(ROC) analysis. Combined predictive power of the best prognostic parameters was tested with the use of linear discriminant analysis.·RESULTS: IMH closure was achieved in 106 eyes(92%)in the prospective group and 49 eyes(89%) in the retrospective group. Despite anatomical closure, the outer retinal structure was not restored in two eyes in the first group and in one eye in the second group.Preoperative central subfield retinal thickness demonstrated the best discriminatory capability between eyes with anatomical success and failure: area under the ROC-curve(AUC) 0.938(95% CI: 0.881-0.995), sensitivity64% at fixed specificity 95%(cut-off value 300 μm) in the prospective group; sensitivity 57% and specificity 90% in the retrospective group. Other continuous parameters except tractional hole index(AUC: 0.796, 95% CI: 0.591-1.000) had significantly lower AUCs(P <0.05). The best combination of the parameters, established by discriminant analysis in the prospective group, could not confirm its predictive value in the retrospective group.· CONCLUSION: Preoperative central subfield retinalthickness is a strong and probably the best predictor of anatomical results of IMH surgical treatment. | Alexander A.Shpak Dmitry O.Shkvorchenko Ilias Kh.Sharafetdinov Olga A.Yukhanova | 2016 | International Journal of Ophthalmology(English edition)2016,9,2: | 10 |
| 6 | Effect of bombesin and neurotensin on gut barrier function in partially hepatectomized rats显示文摘AIM: To investigate the effect of regulatory peptides bombesin (BBS) and neurotensin (NT) on intestinal barrier function in partially hepatectomized rats.METHODS: Ninety male Wistar rats were randomly divided into five groups: Ⅰ (n = 10): controls, Ⅱ (n =20): sham operated, Ⅲ (n = 20): partial hepatectomy 70% (PHx), Ⅳ (n = 20): PHx+BBS (30 μg/kg/d), Ⅴ (n= 20): PHx+NT (300 μg/kg/d). Groups Ⅳ and Ⅴ were treated for 8 days before PHx and 48 h post surgery.At the end of the experiment, on day 10, intestinal barrier function was assessed by measuring endotoxin concentrations in portal and aortic blood. Tissue sections of the terminal ileum were examined histologically and villus density, mucosal thickness, mitotic activity and apoptosis in crypts were assessed. In addition, ileal mucosa was analyzed for DNA and protein content and microbiological analysis was performed in cecal contents.To estimate intestinal oxidative stress, lipid peroxidation was determined on tissue homogenates from terminal ileum.RESULTS: BBS or NT administration significantly reduced portal and systemic endotoxemia observed 48 h after partial hepatectomy. In hepatectomized rats (group Ⅲ), a trend towards induction of mucosal atrophy was observed, demonstrated by the reduction of villus density, mucosal thickness, protein content and significant reduction of DNA, while these alterations were reversed by regulatory peptides administration.This trophic effect of BBS and NT was accompanied by induction of mitoses above control levels and a significant reduction of apoptosis in intestinal crypts.Intestinal lipid peroxidation was found significantly lower in PHx group and regulatory peptides exerted an antioxidant action, further decreasing this parameter of oxidative stress. The bacterial population of E. coli and aerobic Gram (+) cocci was increased in cecal content of hepatectomized rats, while this parameter was not affected by the administration of BBS or NT.CONCLUSION: Gut regulatory peptides BBS and NT improve intestinal barrier function and reduce endotoxemia in experimental partial hepatectomy. This effect is, at least in part, mediated by their trophic,antiapoptotic, mitogenic, and antioxidant effect on the intestinal epithelium. This observation might be of potential value in patients undergoing liver resection. | Stelios F Assimakopoulos Ilias H Alexandris Chrisoula D Scopa Panagiotis G Mylonas Konstantinos C Thomopoulos Christos D Georgiou Vassiliki N Nikolopoulou Constantine E Vagianos | 2005 | World Journal of Gastroenterology2005,11,43: | 8 |
| 7 | Liver histology in ICU patients dying from sepsis:A clinico-pathological study显示文摘AIM:To determine end-stage pathologic changes in the liver of septic patients dying in the intensive care unit. METHODS: Needle liver biopsies obtained immediately after death from 15 consecutive patients with sepsis and no underlying liver disease were subjected to routine histological examination. Liver function tests and clinical monitoring measurements were also recorded. RESULTS: Liver biochemistries were increased in the majority of patients before death. Histology of liver bi- opsy specimens showed portal inflammation in 73.3%, centrilobular necrosis in 80%, lobular inflammation in 66.7%, hepatocellular apoptosis in 66.6% and cholan- gitis/cholangiolitis in 20% of patients. Mixed hepatitic/ cholestatic type of liver injury was observed in 6/15 (40%) patients and hepatitc in 9/15 (60%). Steatosis was ob- served in 11/15 (73.3%) patients affecting 5%-80% of liver parenchyma. Among the histological features, the presence of portal inflammation in liver biopsy was as- sociated with increased hospitalization in the ICU prior death (P = 0.026). CONCLUSION: Features of hepatitis and steatosis arethe main histological findings in the liver in the majority of patients dying from sepsis. | John Koskinas Ilias P Gomatos Dina G Tiniakos Nikolaos Memos Maria Boutsikou Aspasia Garatzioti Athanasios Archimandritis Alexander Betrosian | 2008 | World Journal of Gastroenterology2008,14,9: | 8 |
| 8 | Meta-analysis of subtotal stomach-preserving pancreaticoduodenectomy vs pylorus preserving pancreaticoduodenectomy显示文摘AIM: To investigate the differences in outcome following pylorus preserving pancreaticoduodenectomy(PPPD) and subtotal stomach-preserving pancreaticoduodenectomy(SSPPD).METHODS: Major databases including Pub Med(Medline), EMBASE and Science Citation Index Expanded and the Cochrane Central Register of Controlled Trials(CENTRAL) in The Cochrane Library were searched for comparative studies between patients with PPPD and SSPPD published between January 1978 and July 2014. Studies were selected based on specific inclusion and exclusion criteria. The primary outcome was delayed gastric emptying(DGE). Secondary outcomes included operation time, intraoperative blood loss, pancreatic fistula, postoperative hemorrhage, intraabdominal abscess, wound infection, time to starting liquid diet, time to starting solid diet, period of nasogastric intubation, reinsertion of nasogastric tube, mortality and hospital stay. The pooled odds ratios(OR) or weighted mean difference(WMD) with 95% confidence intervals(95%CI) were calculated using either a fixed-effects or random-effects model. RESULTS: Eight comparative studies recruiting 650 patients were analyzed, which include two RCTs, one non-randomized prospective and 5 retrospective trial designs. Patients undergoing SSPPD experienced significantly lower rates of DGE(OR = 2.75; 95%CI: 1.75-4.30, P < 0.00001) and a shorter period of nasogastric intubation(OR = 2.68; 95%CI: 0.77-4.58,P < 0.00001), with a tendency towards shorter time to liquid(WMD = 2.97, 95%CI:-0.46-7.83; P = 0.09) and solid diets(WMD = 3.69, 95%CI:-0.46-7.83; P = 0.08) as well as shorter inpatient stay(WMD = 3.92, 95%CI:-0.37-8.22; P = 0.07), although these latter three did not reach statistical significance. PPPD, however, was associated with less intraoperative blood loss than SSPPD [WMD =-217.70, 95%CI:-429.77-(-5.63); P = 0.04]. There were no differences in other parameters between the two approaches, including operative time(WMD =-5.30, 95%CI:-43.44-32.84; P = 0.79), pancreatic fistula(OR = 0.91; 95%CI: 0.56-1.49; P = 0.70), postoperative hemorrhage(OR = 0.51; 95%CI: 0.15-1.74; P = 0.29), intraabdominal abscess(OR = 1.05; 95%CI: 0.54-2.05; P = 0.89), wound infection(OR = 0.88; 95%CI: 0.39-1.97; P = 0.75), reinsertion of nasogastric tube(OR = 1.90; 95%CI: 0.91-3.97; P = 0.09) and mortality(OR = 0.31; 95%CI: 0.05-2.01; P = 0.22).CONCLUSION: SSPPD may improve intraoperative and short-term postoperative outcomes compared to PPPD, especially DGE. However, these findings need to be further ascertained by well-designed randomized controlled trials. | Wei Huang Jun-Jie Xiong Mei-Hua Wan Peter Szatmary Shameena Bharucha Ilias Gomatos Quentin M Nunes Qing Xia Robert Sutton Xu-Bao Liu | 2015 | World Journal of Gastroenterology2015,21,20: | 8 |
| 9 | Patterns of airway involvement in inflammatory bowel diseases显示文摘Extraintestinal manifestations occur commonly in inflammatory bowel diseases(IBD). Pulmonary manifestations(PM) of IBD may be divided in airway disorders, interstitial lung disorders, serositis, pulmonary vasculitis, necrobiotic nodules, drug-induced lung disease, thromboembolic lung disease and enteropulmonary fistulas. Pulmonary involvement may often be asymptomatic and detected solely on the basis of abnormal screening tests. The common embryonic origin of the intestine and the lungs from the primitive foregut, the co-existence of mucosa associated lymphoid tissue in both organs, autoimmunity, smoking and bacterial translocation from the colon to the lungs may all be involved in the pathogenesis of PM in IBD. PM are mainly detected by pulmonary function tests and highresolution computed tomography. This review will focus on the involvement of the airways in the context of IBD, especially stenoses of the large airways, tracheo-bronchitis, bronchiectasis, bronchitis, mucoid impaction, bronchial granulomas, bronchiolitis, bronchiolitis obliterans syndrome and the co-existence of IBD with asthma, chronic obstructive pulmonary disease, sarcoidosis and a1-antitrypsin deficiency. | Ilias Papanikolaou Konstantinos Kagouridis Spyros A Papiris | 2014 | World Journal of Gastrointestinal Pathophysiology2014,5,4: | 7 |
| 10 | Prophylactic intra-peritoneal drain placement following pancreaticoduodenectomy:A systematic review and metaanalysis显示文摘AIM:To conduct a meta-analysis comparing outcomes after pancreaticoduodenectomy(PD)with or without prophylactic drainage.METHODS:Relevant comparative randomized and nonrandomized studies were systemically searched based on specific inclusion and exclusion criteria.Postoperative outcomes were compared between patients with and those without routine drainage.Pooled odds ratios(OR)with 95%CI were calculated using either fixed effects or random effects models.RESULTS:One randomized controlled trial and four non-randomized comparative studies recruiting 1728patients were analyzed.Patients without prophylactic drainage after PD had significantly higher mortality(OR=2.32,95%CI:1.11-4.85;P=0.02),despite the fact that they were associated with fewer overall complications(OR=0.62,95%CI:0.48-0.82;P=0.00),major complications(OR=0.75,95%CI:0.60-0.93;P=0.01)and readmissions(OR=0.77,95%CI:0.60-0.98;P=0.04).There were no significant differences in the rates of pancreatic fistula,intraabdominal abscesses,postpancreatectomy hemorrhage,biliary fistula,delayed gastric emptying,reoperation or radiologic-guided drains between the two groups.CONCLUSION:Indiscriminate abandonment of intraabdominal drainage following PD is associated with greater mortality,but lower complication rates.Future randomized trials should compare routine vs selective drainage. | Yi-Chao Wang Peter Szatmary Jing-Qiang Zhu Jun-Jie Xiong Wei Huang Ilias Gomatos Quentin M Nunes Robert Sutton Xu-Bao Liu | 2015 | World Journal of Gastroenterology2015,21,8: | 7 |
| 11 | Targeting protein lysine methylation and demethylation in cancers显示文摘在最后十年期间,我们看见了调查 histones 和 non-histone 蛋白质的离氨酸 methylation/demethylation 的角色的研究的爆炸,例如 p53, NF-kappaB,和 E2F1。这些 Ying-Yang translational 以后修正对调整这些蛋白质的活动重要。离氨酸 methylation 和 demethylation 被蛋白质离氨酸 methyltransferases (PKMT ) 和蛋白质离氨酸 demethylases (PKDM ) 催化。PKMT, PKDM,和他们的底层被显示了在癌症起重要作用。尽管 tumorigenesis 的内在的机制大部分仍然是未知的,成长证据开始正在连接 methylation 的异常规定到 tumorigenesis。这评论集中于为 PKMT 和 PKDM 在蛋白质离氨酸 methylation 的功能的理解,并且在小分子禁止者的发现总结最近的进步。我们也讨论潜力和为癌症的治疗指向蛋白质离氨酸 methylation 的警告。 | Yunlong He Ilia Korboukh Jian Jin Jing Huang | 2012 | Acta Biochimica et Biophysica Sinica2012,44,1: | 6 |
| 12 | Managing high risk glaucoma with the Ahmed valve implant:20 years of experience显示文摘AIM: To estimate the efficacy and safety of the Ahmed implant in patients with high risk for failure after glaucoma surgery.METHODS: In 342 eyes of 342 patients with refractory glaucoma, even with application of medical treatment, the Ahmed valve was introduced for intraocular pressure(IOP) control, in the period of the last 20y. The nature of glaucoma was neovascular in 162 eyes, pseudophakic or aphakic in 49 eyes, inflammatory in 29 eyes and non working previous antiglaucomatic surgical interventions in 102 eyes. RESULTS: Follow-up ranged from 18 to 120m o with a mean follow-up of 63.2m o. IOP before the operation decreased from 31.6±10.4 mmHg to 18.3±5.4 mm Hg(no systemic treatment) at the end of follow up period. When we compared the IOP values before the operation using ANOVA showed statistically significant difference(P<0.001). The success rate was 85.2% during the first semester, 76.8% at 12 mo and 50.3% at the end of follow up period(18 to 120 mo after implantation). Success rate was 25.7% in neovascular glaucoma, 63.2% in aphakic glaucoma and 73.8% in non working previous antiglaucomatic surgical interventions. Complications due to the implant were: serous choroidal detachment in 14.8%, blockage of the tube in 2.8%, malposition of the tube in 4.9%, suprachoroidal hemorrhage in 2.1%, cataract progression in 39.6%(phakic eyes), shallow anterior chamber in 9.2%, hyphaema in 28.9%, exposure of valve in 2.6%, exposure of tube in 9.3%, hypotony in 4.9% and conjunctival fibrosis in 41.5%.CONCLUSION: Despite the fact that Ahmed valve implant had suchlike results as other implants concerning the IOP control, complications rate due to hypotony or over filtration in the first days after the intervention are not that frequent as with other valve implants. | tryfon rotsos anastasia tsioga konstantinos andreanos andreas diagourtas petros petrou ilias georgalas dimitrios papaconstantinou | 2018 | International Journal of Ophthalmology(English edition)2018,11,2: | 5 |
| 13 | Emerging neuromodulatory molecules for the treatment of neurogenic erectile dysfunction caused by cavernous nerve injury显示文摘在细胞死亡的生长因素,神经发展,和预防的神经生物学的进展为多孔的神经( CN )为保护、再生的 neuromodulatory 策略的发展导致了提高的临床的兴趣,当为前列腺癌症和另外的骨盆的恶意的治疗经常导致神经元损坏和性功能的削弱的损失。氮的氧化物在平滑肌的阴茎海绵体原因松驰以内免除了这些神经的轴索终板,开始象贡献维持的肿大一样的阴茎勃起的 haemodynamic 变化;CN 功能的损失在骨盆的外科以后为可勃起的机能障碍(编辑) 的开发主要负责并且为潜在的 neuroprotective 或再生策略用作主要目标。从为精选 neuromodulatory 途径的现出症状之前的潜的研究的证据被考察,包括 neurotrophins,神经胶质房间导出线的神经营养的因素(GDNF ) ,骨头 morphogenic 蛋白质, immunophilin ligands, erythropoetin (EPO ) ,和干细胞。 | Anthony J. Bella Guiting Lin Ilias Cagiannos Tom F. Lue | 2008 | Asian Journal of Andrology2008,10,1: | 5 |
| 14 | Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms显示文摘The infusion of coronavirus disease 2019(COVID-19)patients with mesenchymal stem cells(MSCs)potentially improves clinical symptoms,but the underlying mechanism remains unclear.We conducted a randomized,single-blind,placebo-controlled(29 patients/group)phase II clinical trial to validate previous findings and explore the potential mechanisms.Patients treated with umbilical cord-derived MSCs exhibited a shorter hospital stay(P=0.0198)and less time required for symptoms remission(P=0.0194)than those who received placebo.Based on chest images,both severe and critical patients treated with MSCs showed improvement by day 7(P=0.0099)and day 21(P=0.0084).MSC-treated patients had fewer adverse events.MSC infusion reduced the levels of C-reactive protein,proinflammatory cytokines,and neutrophil extracellular traps(NETs)and promoted the maintenance of SARS-CoV-2-specific antibodies.To explore how MSCs modulate the immune system,we employed single-cell RNA sequencing analysis on peripheral blood.Our analysis identified a novel subpopulation of VNN2+hematopoietic stem/progenitorlike(HSPC-like)cells expressing CSF3R and PTPRE that were mobilized following MSC infusion.Genes encoding chemotaxis factors—CX3CR1 and L-selectin—were upregulated in various immune cells.MSC treatment also regulated B cell subsets and increased the expression of costimulatory CD28 in T cells in vivo and in vitro.In addition,an in vivo mouse study confirmed that MSCs suppressed NET release and reduced venous thrombosis by upregulating kindlin-3 signaling.Together,our results underscore the role of MSCs in improving COVID-19 patient outcomes via maintenance of immune homeostasis. | Rongjia Zhu Tingdong Yan Yingmei Feng Yan Liu Hongcui Cao Gongxin Peng Yanlei Yang Zhen Xu Jingqi Liu Wei Hou Xiaoyue Wang Zhe Li Luchan Deng Shihua Wang Jing Li Qin Han Hongling Li Guangliang Shan Yinghao Cao Xingyan An Jianshe Yan Zhonghui Zhang Huafei Li Xuebin Qu Jiaqi Zhu Shumin Zhou Jiao Wang Fengchun Zhang Jinming Gao Ronghua Jin Dayong Xu Yan-Qing Ma Tao Huang Shuang Peng Zhi Zheng Ilia Stambler Eric Gilson Lee Wei Lim Alexey Moskalev Antonio Cano Sasanka Chakrabarti Brun Ulfhake Huanxing Su Haoying Xu Sihuan Xu Feng Wei Holly MBrown-Borg Kyung-Jin Min Georgina Ellison-Hughes Calogero Caruso Kunlin Jin Robert Chunhua Zhao | 2021 | Cell Research2021,31,12: | 5 |
| 15 | 从勃姆石−高岭石型高硅铝土矿中盐酸浸出铁的机理与动力学显示文摘利用XRD、ICP-OES、TG/DSC、SEM、TEM和穆斯堡尔(Mössbauer)光谱研究来自俄罗斯阿尔汉格尔斯克地区Severoonezhsk铝矿中铝土矿的化学和矿物组成,发现该铝土矿的含铁矿物包括铝针铁矿(α-Fe_(1−x)Al_(x)OOH)、铝赤铁矿(α-(Fe_(1−x)Al_(x))_(2)O_(3))、正方铝针铁矿(β-Fe_(1−x)Al_(x)O(OH,Cl))和铬铁矿(FeCr_(2)O_(4))。在温度为100℃、HCl浓度为10%,固液比为1:10及浸出时间为60 min的条件下,盐酸浸出铝土矿的铁浸出率为82.5%,而铝的损失不到铝土矿中总铝含量的4.5%。铁浸出过程的动力学分析表明,温度为90~100℃时,扩散是浸出过程的速率限制环节。铝土矿浸出渣含有微量的α-Fe_(1−x)Al_(x)OOH和β-Fe_(1−x)Al_(x)O(OH,Cl),大部分铁呈FeCr_(2)O_(4)形态。除铁氧化物外,铝土矿盐酸浸出渣中铬和钙氧化物的含量也显著降低。含氯化铁的浸出液含有稀土元素(REE):6.8 mg/L Sc、4.1 mg/L Ce和2.3 mg/L Ga。 | Dmitry VALEEV Denis PANKRATOV Andrei SHOPPERT Artem SOKOLOV Alexandr KASIKOV Alexandra MIKHAILOVA Cristian SALAZAR-CONCHA Ilia RODIONOV | 2021 | Transactions of Nonferrous Metals Society of China2021,31,10: | 4 |
| 16 | Molecular markers(PECAM-1,ICAM-3,HLA-DR)determine prognosis in primary non-Hodgkin's gastric lymphoma patients显示文摘瞄准:与主要 non-Hodgkin 的胃的淋巴瘤在病人调查 PECAM-1, ICAM-3 和 HLA 医生抗原的预示的意义。方法:我们免疫组织化学地在 36 个 B 房间麦芽类型主要胃的淋巴瘤病人学习了 PECAM-1, ICAM-3 和 HLA 医生抗原表示。十非恶意并且十个健康胃的织物标本被用作控制。Clinicopathological 和幸存数据与染色的结果被相关。结果:HLA 医生抗原表示在 33 个胃的淋巴瘤病人(91.7%) 和 6 个非恶意的病人(54.5%) 被检测。PECAM-1 染色了 10 个病人(27.8%) 的肿瘤房间, 9 个病人(25%) 的 endothelial 并且煽动性有良性的胃的疾病的 4 个病人(40%) 渗入。ICAM-3 表示在 17 个病人(47.2%) 的肿瘤房间上被观察,当 5 个非恶意的病人(50%) 被染色时积极也。任何一个都没为任何学习的基因健康控制被染色。在里面多,变量分析, HLA 医生抗原和 PECAM-1 被证明是与联系的统计上重要的独立预示的因素一赞成并且不利预后分别地(P=0.009 和 P=0.003 ) 。在 univariate 分析, PECAM-1 (+)/ICAM-3 (-) 和 HLA 医生(-)/ICAM-3 (-) 病人与确切相反的基因表示模式与那些相比展出了显著地减少的全面幸存(P=0.0041 和 P=0.0091,分别地) 。是 HLA 医生(+)/ICAM-3 (+)/PECAM-1 (-)(n=8 ) 的那些病人让显著地更高的幸存与这个组(n=24 )(P=0.0289 ) 的其余部分相比评价。结论:PECAM-1, ICAM-3 和 HLA 医生分别地是肿瘤扩大潜力和主人免疫者监视的代表性的标记。他们的联合使用可以帮助我们识别能得益于更好攻击的治疗学的协议的高风险的病人。 | Alexander Darom Ilias P Gomatos Emmanuel Leandros Emmu Chatzigianni Dimitris Panousopoulos Manousos M Konstadoulakis George Androulakis | 2006 | World Journal of Gastroenterology2006,12,12: | 4 |
| 17 | Spatiotemporal rotational dynamics of laser-driven molecules显示文摘Molecular alignment and orientation by laser fields has attracted significant attention in recent years,mostly due to new capabilities to manipulate the molecular spatial arrangement.Molecules can now be efficiently prepared for ionization,structural imaging,orbital tomography,and more,enabling,for example,shooting of dynamic molecular movies.Furthermore,molecular alignment and orientation processes give rise to fundamental quantum and classical phenomena like quantum revivals,Anderson localization,and rotational echoes,just to mention a few.We review recent progress on the visualization,coherent control,and applications of the rich dynamics of molecular rotational wave packets driven by laser pulses of various intensities,durations,and polarizations.In particular,we focus on the molecular unidirectional rotation and its visualization,the orientation of chiral molecules,and the three-dimensional orientation of asymmetric-top molecules.Rotational echoes are discussed as an example of nontrivial dynamics and detection of prepared molecular states. | Kang Lin Ilia Tutunnikov Junyang Ma Junjie Qiang Lianrong Zhou Olivier Faucher Yehiam Prior Ilya Sh.Averbukh Jian Wu | 2020 | Advanced Photonics2020,2,2: | 4 |
| 18 | Larvicidal efficacies and chemical composition of essential oils of Pinus sylvestris and Syzygium aromaticum against mosquitoes显示文摘Objective:To assess the chemical composition and mosquito larvicidal potentials of essential oils of locally sourced Pinus sylvestris(P.sylvestris)and Syzygium aromatkum(S.aromaticum)against Aedes aegypti(A.aegypti)and Culex quinquefasciatus(C.quinquefasciatus).Method:The chemical composition of the essential oils of both plants was determined using GCMS while the larvicidal bioassay was carried out using different concentrations of the oils against the larvae of A.aegypti and C.quinquefasciatus in accordance with the standard protocol.Results:The results as determined by GC-MS showed that oil of S.aromaticum has eugenol(80.5%)as its principal constituent while P.sylvestris has 3-Cyclohexene-1-methanol,.alpha.,.alpha.4-trimethyl(27.1%)as its dominant constituent.Both oils achieved over 85%larval mortality within24 h.The larvae of A.aegypti were more susceptible to the oils[LC_(50)(S.aromaticum)=92.56 mg/L,LC_(50)(P.sylvestris)=100.39 mg/L]than C.quinquefasciatus[LC_(50)(S.aromaticum)=124.42 mg/L;LC_(50)(P.sylvestris)=128.00 mg/L].S.aromaticum oil was more toxic to the mosquito larvae than oil of P.sylvatris but the difference in lethal concentrations was insignificant(P>0.05).Condusioii:The results justify the larvicidal potentials of both essential oils and the need to incorporate them in vector management and control. | Kehinde Adenike Fayemiwo Monsuru Adebayo Adeleke Ovie Princewill Okoro Shola Hezekiah Awojide Ilias Olufemi Awoniyi | 2014 | Asian Pacific Journal of Tropical Biomedicine2014,4,1: | 4 |
| 19 | Sigmoid schwannoma: A rare case显示文摘Schwannomas are rare tumors derived from the cells of Schwann that form the neural sheath. When located in the gastrointestinal tract, they constitute together with leiomyoma, leiomyoblastoma, and leiomyosarcoma, the gastrointestinal stromal tumors (GIST). Peripheral nerve sheath tumors represent 2-6% GIST with most common location, the stomach and the small intestine. Schwannomas of the colon and rectum are extremely rare and radical excision with wide margins is mandatory, due to their tendency to recur locally and become malignant, if left untreated. In the present study, we report a rare case of a sigmoid schwannoma, which was successfully treated in our department and reviewed the literature. | Constantine I.Fotiadis Ilias A.Kouerinis Ioannis Papandreou George C.Zografos George Agapitos | 2005 | World Journal of Gastroenterology2005,11,32: | 4 |
| 20 | Earnings volatility and earnings predictability显示文摘 | Ilia D. Dichev Vicki Wei Tang | 2008 | Journal of Accounting and Economics2008,,1: | 4 |