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| 1 | Autologous transplantation of bone marrow mesenchymal stem cells on diabetic patients with lower limb ischemia显示文摘学习骨头髓的自体同源的移植的功效和安全的目的有更低的手足局部缺血的糖尿病的病人上的间充质的干细胞。有更低的手足局部缺血的五十种类型 2 糖尿病的病人被注册并且使随机化到也的方法移植了组或控制组。病人在两个都,组接受了一样的常规治疗。同时,从每个移植病人的 20 ml 骨头髓被收集,并且间充质的干细胞被密度坡度 centrifugation 分开并且在有自体同源的浆液的媒介有教养。在在 vitro 的三星期的支持者文化以后, 7.32 ????????????????? 金 ???????????? ㈠ ?????? ┷? | Lu Debin Jiang Youzhao Liang Ziwen Li Xiaoyan Zhang Zhonghui Chen Bing | 2008 | Journal of Medical Colleges of PLA(China)2008，23，2： | 16 |
| 2 | Abundance of antibiotic resistance genes and their association with bacterial communities in activated sludge of wastewater treatment plants: Geographical distribution and network analysis显示文摘Wastewater treatment plants(WWTPs) are deemed reservoirs of antibiotic resistance genes(ARGs). Bacterial phylogeny can shape the resistome in activated sludge. However, the co-occurrence and interaction of ARGs abundance and bacterial communities in different WWTPs located at continental scales are still not comprehensively understood. Here, we applied quantitative PCR and Miseq sequence approaches to unveil the changing profiles of ARGs(sul1, sul2, tet W, tet Q, tet X), int I1 gene, and bacterial communities in 18 geographically distributed WWTPs. The results showed that the average relative abundance of sul1 and sul2 genes were 2.08 × 10^(-1) and 1.32 × 10^(-1) copies/16 S rRNA copies, respectively. The abundance of tet W gene was positively correlated with the Shannon diversity index(H′), while both studied sul genes had significant positive relationship with the int I1 gene. The highest average relative abundances of sul1, sul2, tet X, and int I1 genes were found in south region and oxidation ditch system. Network analysis found that 16 bacterial genera co-occurred with tet W gene. Co-occurrence patterns were revealed distinct community interactions between aerobic/anoxic/aerobic and oxidation ditch systems. The redundancy analysis model plot of the bacterial community composition clearly demonstrated that the sludge samples were significant differences among those from the different geographical areas,and the shifts in bacterial community composition were correlated with ARGs. Together,these findings from the present study will highlight the potential risks of ARGs and bacterial populations carrying these ARGs, and enable the development of suitable technique to control the dissemination of ARGs from WWTPs into aquatic environments. | Haihan Zhang Huiyan He Shengnan Chen Tinglin Huang Kuanyu Lu Zhonghui Zhang Rong Wang Xueyao Zhang Hailong Li | 2019 | Journal of Environmental Sciences2019，31，8： | 9 |
| 3 | Electrochemical hydrogen storage characteristics of La_(0.75-x) M_xMg_(0.25)Ni_(3.2)Co_(0.2)Al_(0.1)(M=Zr,Pr;x=0,0.1) alloys prepared by melt spinning显示文摘In order to ameliorate the electrochemical hydrogen storage performances of La-Mg-Ni system A_2B_7-type electrode alloys, the partial substitution of M (M = Zr, Pr) for La was performed. The melt spinning technology was used to fabricate the La_(0.75-x)M_xMg_0.25Ni_3.2Co_0.2Al_0.1 (M = Zr, Pr; x = 0, 0.1) electrode alloys. The influences of the melt spinning and substituting La with M (M = Zr, Pr) on the structures and the electrochemical hydrogen storage characteristics of the alloys were investigated. The analysis of XRD, SEM, and TEM reveals that the as-cast and spun alloys have a multiphase structure composed of two main phases (La, Mg)_2Ni_7 and LaNi_5 as well as a residual phase LaNi_2 . The as-spun (M = Pr) alloy displays an entire nanocrystalline structure, while an amorphous-like structure is detected in the as-spun (M = Zr) alloy, implying that the substitution of Zr for La facilitates the amorphous formation. The electrochemical measurements exhibit that the substitution of Pr for La clearly increases the discharge capacity of the alloys; however, the Zr substitution brings on an adverse impact. Meanwhile, the M (M = Zr, Pr) substitution significantly enhances its cycle stability. The melt spinning exerts an evident effect on the electrochemical performances of the alloys, whose discharge capacity and high rate discharge ability (HRD) first mount up and then fall with the growing spinning rate, whereas their cycle stabilities monotonously augment as the spinning | ZHANG Yanghuan YANG Tai CAI Ying HOU Zhonghui REN Huiping ZHAO Dongliang | 2012 | Rare Metals2012，31，5： | 7 |
| 4 | DRAGON-Lab―Next generation internet technology experiment platform显示文摘Testbed technology is very important in the development of the Internet. Similar to the present internet,next generation internet also starts from testbed. There are two kinds of testbeds,testbed networks like CNGI-CERNET2,Internet2,Geant;testbed systems like PlanetLab,NS2. DRAGON-Lab can be viewed as both testbed network and testbed system. DRAGON-Lab is an independent AS(autonomous system) and connected to multiple real networks. On the other hand,DRAGON-Lab integrates many resources of its own,partners' and internet's,so as to provide open service. DRAGON-Lab has a large scale,provides open service,supports remote visualized experiments and programmable experiments. More details will be introduced in this paper. | WANG JiLong LI ZhongHui LV GuoHan JIANG CaiPing LI Xing ZHANG QianLi | 2008 | Science in China(Series F)2008，51，11： | 6 |
| 5 | Exosomal LINC00355 derived from cancer-associated fibroblasts promotes bladder cancer cell resistance to cisplatin by regulating miR-34b-5p/ABCB1 axis显示文摘Cisplatin resistance is a major challenge for bladder cancer(BC).Evidence indicates that exosome derived from cancer-associated fibroblasts(CAF-Exo)can promote chemotherapy resistance in various human tumors by delivering bioactive molecules.We have previously demonstrated that CAF-derived exosomal LINC00355 promotes BC cell proliferation and invasion.However,the underlying mechanisms are still unclear.In this study,we aimed to investigate the role and mechanisms of CAF-derived exosomal LINC00355 in BC cell resistance to cisplatin.Exosomes were isolated from normal fibroblasts(NFs)and BC tumor-derived CAFs,namely,NF-Exo and CAF-Exo.CAFs were transfected with si-Ctrl or si-LINC00355 and then different exosomes were isolated,namely,CAF^(si-Ctrl)-Exo and CAF^(si-LINC00355)-Exo.The human BC cell lines(T24 and 5367)were incubated with NF-Exo,CAF-Exo,CAF^(si-Ctrl)-Exo,and CAF^(si-LINC00355)-Exo in the presence of cisplatin.MTT proliferation assay and flow cytometric analysis showed that CAF-Exo promoted BC cell resistance to cisplatin and upregulated ABCB1 expression in BC cells by transferring LINC00355 to BC cells.Luciferase activity assay confirmed the interaction between miR-34b-5p and LINC00355 or ABCB1.qRT-PCR and western blot analysis further showed that LINC00355 sponged miR-34b-5p to upregulate ABCB1 expression.However,the promoting effects of CAF-Exo on BC cell resistance to cisplatin were abolished by miR-34b-5p overexpression and ABCB1 silencing.In conclusion,exosomal LINC00355 derived from CAFs promotes BC cell resistance to cisplatin by regulating the miR-34b-5p/ABCB1 axis. | Guangyue Luo Yangyang Zhang Zhonghui Wu Ligang Zhang Chaozhao Liang Xianguo Chen | 2021 | Acta Biochimica et Biophysica Sinica2021，53，5： | 6 |
| 6 | Rational design of novel ultra-small amorphous Fe_(2)O_(3)nanodots/graphene heterostructures for all-solid-state asymmetric supercapacitors显示文摘Constructing graphene-based heterostructures with large interfacial area is an efficient approach to enhance the electrochemical performance of supercapacitors but remains great challenges in their synthesis.Herein,a novel ultra-small amorphous Fe_(2)O_(3)nanodots/graphene heterostructure(a-Fe_(2)O_(3)NDs/RGO)aerogel was facilely synthesized via excessive metal-ion-induced self-assembly and subsequent calcination route using Prussian blue/graphene oxide(PB/GO)composite aerogel as precursors.The deliberately designed a-Fe_(2)O_(3)NDs/RGO heterostructure offers a highly interconnected porous conductive network,large heterostructure interfacial area,and plenty of accessible active sites,greatly facilitating the electron transfer,electrolyte diffusion,and pseudocapacitive reactions.The obtained a-Fe_(2)O_(3)NDs/RGO aerogel could be used as flexible free-standing electrodes after mechanical compression,which exhibited a significantly enhanced specific capacitance of 347.4 F·g^(-1)at 1 A·g^(-1),extraordinary rate capability of 184 F·g^(-1)at 10 A·g^(-1),and decent cycling stability.With the as-prepared a-Fe_(2)O_(3)NDs/RGO as negative electrodes and the Co_(3)O_(4)NDs/RGO as positive electrodes,an all-solid-state asymmetric supercapacitor(a-Fe_(2)O_(3)NDs/RGO//Co_(3)O_(4)NDs/RGO asymmetric supercapacitor(ASC))was assembled,which delivered a high specific capacitance of 69.1 F·g^(-1)at 1 A·g^(-1)and an impressive energy density of 21.6 W·h·k·g^(-1)at 750 W·k·g^(-1),as well as good cycling stability with a capacity retention of 94.3%after 5,000 cycles.This work provides a promising avenue to design high-performance graphene-based composite electrodes and profound inspiration for developing advanced flexible energy-storage devices. | Chenxiao Wu Zhifang Zhang Zhonghui Chen Zuimin Jiang Huiyu Li Haijing Cao Yongsheng Liu Yanyan Zhu Zebo Fang Xiangrong Yu | 2021 | Nano Research2021，14，4： | 6 |
| 7 | Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms显示文摘The infusion of coronavirus disease 2019(COVID-19)patients with mesenchymal stem cells(MSCs)potentially improves clinical symptoms,but the underlying mechanism remains unclear.We conducted a randomized,single-blind,placebo-controlled(29 patients/group)phase II clinical trial to validate previous findings and explore the potential mechanisms.Patients treated with umbilical cord-derived MSCs exhibited a shorter hospital stay(P=0.0198)and less time required for symptoms remission(P=0.0194)than those who received placebo.Based on chest images,both severe and critical patients treated with MSCs showed improvement by day 7(P=0.0099)and day 21(P=0.0084).MSC-treated patients had fewer adverse events.MSC infusion reduced the levels of C-reactive protein,proinflammatory cytokines,and neutrophil extracellular traps(NETs)and promoted the maintenance of SARS-CoV-2-specific antibodies.To explore how MSCs modulate the immune system,we employed single-cell RNA sequencing analysis on peripheral blood.Our analysis identified a novel subpopulation of VNN2+hematopoietic stem/progenitorlike(HSPC-like)cells expressing CSF3R and PTPRE that were mobilized following MSC infusion.Genes encoding chemotaxis factors—CX3CR1 and L-selectin—were upregulated in various immune cells.MSC treatment also regulated B cell subsets and increased the expression of costimulatory CD28 in T cells in vivo and in vitro.In addition,an in vivo mouse study confirmed that MSCs suppressed NET release and reduced venous thrombosis by upregulating kindlin-3 signaling.Together,our results underscore the role of MSCs in improving COVID-19 patient outcomes via maintenance of immune homeostasis. | Rongjia Zhu Tingdong Yan Yingmei Feng Yan Liu Hongcui Cao Gongxin Peng Yanlei Yang Zhen Xu Jingqi Liu Wei Hou Xiaoyue Wang Zhe Li Luchan Deng Shihua Wang Jing Li Qin Han Hongling Li Guangliang Shan Yinghao Cao Xingyan An Jianshe Yan Zhonghui Zhang Huafei Li Xuebin Qu Jiaqi Zhu Shumin Zhou Jiao Wang Fengchun Zhang Jinming Gao Ronghua Jin Dayong Xu Yan-Qing Ma Tao Huang Shuang Peng Zhi Zheng Ilia Stambler Eric Gilson Lee Wei Lim Alexey Moskalev Antonio Cano Sasanka Chakrabarti Brun Ulfhake Huanxing Su Haoying Xu Sihuan Xu Feng Wei Holly MBrown-Borg Kyung-Jin Min Georgina Ellison-Hughes Calogero Caruso Kunlin Jin Robert Chunhua Zhao | 2021 | Cell Research2021，31，12： | 5 |
| 8 | Cloning of the full-length gene of activin receptor-interacting protein2a and characterization of its interaction with ActR Ⅱ A显示文摘为了调查细胞内部的信号 transduction 的机制,由 activin 受体调停了,编码新奇 activin 的全身的基因交往受体的 protein2a (ARIP2a ) 从一个老鼠大脑 cDNA 图书馆被识别。ARIP2a 和 ARIP2 和在导致 activin 的 RAW264 的 ARIP2 的序列。7 房间被比较,并且在 ARIP2a 和 ActRIIA 之间的相互作用被证实。序列分析表明除了 99 th 氨基酸。RT-PCR 试金证明 ARIP2a mRNA 高度在大脑,垂体和睾丸被表示,并且中等在胰和卵巢,但是在另外的纸巾无法发现。而, ARIP2 mRNA 广泛地在我们测试了的所有老鼠纸巾被散布。而且, ARIP2a mRNA 的表示显著地在刺激 activin 的 RAW264 被减少。7 个房间;然而, ARIP2 mRNA 的表示被增加。另外,在 ARIP2a 之间的相互作用和 activin 类型 IIA 受体(ActRIIA ) 被哺乳动物的二混血儿的试金和下拉试金进一步表明。总起来说,那些结果显示尽管 ARIP2a 对 ARIP2 相应,他们在到 activin 的织物分发和回答是不同的。ARIP2a 能也与 activin 类型 II 受体(ActRIIA ) 交往被哺乳动物的 two-hybird 试金和下拉试金进一步表明。总起来说,那些结果显示尽管 ARIP2a 对 ARIP2 相应,他们在到 activin 的织物分发和回答是不同的。ARIP2a 能也作为 ARIP 家庭的一篇小说与 activin 类型 II 受体交往。 | CUI Xueling TAI Guixiang ZHANG Hongjun FANG Lin LIU Zhonghui | 2007 | Progress in Natural Science:Materials International2007，17，2： | 5 |
| 9 | Estimating the productive potential of five natural forest types in northeastern China显示文摘Background: There is a serious lack of experience regarding the productive potential of the natural forests in northeastern China, which severely limits the development of sustainable forest management strategies for this most important forest region in China. Accordingly, the objective of this study is to develop a first comprehensive system for estimating the wood production for the five dominant forest types.Methods: Based on a network of 384 field plots and using the state-space approach, we develop a system of dynamic stand models, for each of the five main forest types. Four models were developed and evaluated, including a base model and three extended models which include the effects of dominant height and climate variables. The four models were fitted, and their predictive strengths were tested, using the 'seemingly unrelated regression'(SUR) technique.Results: All three of the extended models increased the accuracy of the predictions at varying degrees for the five major natural forest types of northeastern China. The inclusion of dominant height and two climate factors(precipitation and temperature) in the base model resulted in the best performance for all the forest types. On average, the root mean square values were reduced by 13.0% when compared with the base model.Conclusion: Both dominant height and climate factors were important variables in estimating forest production. This study not only presents a new method for estimating forest production for a large region, but also explains regional differences in the effect of site productivity and climate. | Zhaofei Wu Zhonghui Zhang Juan Wang | 2019 | Forest Ecosystems2019，6，4： | 5 |
| 10 | The spatial distribution and factors affecting karst cave development in Guizhou Province显示文摘这研究越过贵州省检验 4960 个洞的分发特征,当探查在洞之间的关系时空间模式和地理元素。这研究基于 hydrogeological 和贵州的地志的地图。ArcGIS 软件被用来处理洞的邻近的索引,空间分析,和联合分析高度和经度,以及岩石性质,岩性学,排水和几乎 5000 个洞的构造分割。基于贵州洞的点模式分析,邻近的索引是 0.53,并且 Tyson 多角形验证的变化的系数到达了 72.469% 。这个数字反映洞的聚类的分发模式。越过全部省,洞被划分成四个集中的区域和一个微弱地影响的区域。四个集中的区域是 Zunyi-Tongren, Bijie, Qianxinan-Liupanshui,和 Guiyang- Anshun-Qinan。一个微弱地影响的地区是 Qiandongnan。大多数在他们之中专注是 Guiyang-Anshun-Qiannan 区域,它盖住 24.67% 全部的省区域,并且说明 36.63% 全部的省洞。在贵州的洞分发在西方的部分作为稠密被描绘并且在东方部分稀少。在这个学习背景下面,形成,包括的岩性学,结构,气候,水文学,和高度的自然元素,和他们洞开发的分发,数字,和空间模式上的效果被分析。 | ZHOU Zhongfa ZHANG Shaoyun XIONG Kangning LI Bo TIAN Zhonghui CHEN Quan YAN Lihui XlAO Shizhen | 2017 | Journal of Geographical Sciences2017，27，8： | 4 |
| 11 | Cenozoic Environmental Changes in the Northern Qaidam Basin Inferred from n-alkane Records显示文摘Cenozoic climatic and environmental changes in the arid Asian interior, and their possible relations with global climatic changes and the Tibetan Plateau uplift, have been intensively investigated and debated over past decades. Here we present 40-Myr(million years)-long n-alkane records from a continuous Cenozoic sediment sequence in the Dahonggou Section, Qaidam Basin, northern Tibetan Plateau, to infer environmental changes in the northern basin. A set of n-alkane indexes, including ACL, CPI and Paq, vary substantially and consistently throughout the records, which are interpreted to reflect relative contributions from terrestrial vascular plants vs. aquatic macrophytes, and thus indicate depositional environments. ACL values vary between 21 and 30; CPI values range from 1.0 to 8.0; and Paq values change from <0.1 to 0.8 over the past 40-Myr. We have roughly identified two periods, at 25.8–21.0 Ma(million years ago) and 13.0–17.5 Ma, with higher ACL and CPI and lower Paq values indicating predominant lacustrine environments. Lower ACL and CPI values, together with higher Paq values, occurred at >25.8 Ma, 17.5–21.0 Ma, and <13.0 Ma, corresponding to alluvial fan/river deltaic deposits and shallow lacustrine settings, consistent with the observed features in sedimentological facies. The inferred Cenozoic environmental changes in the northern Qaidam Basin appear to correspond to global climatic changes. | LIU Zhonghui ZHANG Kexin SUN Yuanyuan LIU Weiguo LIU Yusheng(Christopher) QUAN Cheng | 2014 | Acta Geologica Sinica(English Edition)2014，88，5： | 4 |
| 12 | FT5a interferes with the Dt1-AP1 feedback loop to control flowering time and shoot determinacy in soybean显示文摘Flowering time and stem growth habit determine inflorescence architecture in soybean, which in turn influences seed yield. Dt1, a homolog of Arabidopsis TERMINAL FLOWER 1(TFL1), is a major controller of stem growth habit, but its underlying molecular mechanisms remain unclear.Here, we demonstrate that Dt1 affects node number and plant height, as well as flowering time,in soybean under long-day conditions. The b ZIP transcription factor FDc1 physically interacts with Dt1, and the FDc1-Dt1 complex directly represses the expression of APETALA1(AP1). We propose that FT5 a inhibits Dt1 activity via a competitive interaction with FDc1 and directly upregulates AP1. Moreover, AP1 represses Dt1 expression by directly binding to the Dt1 promoter, suggesting that AP1 and Dt1 form a suppressive regulatory feedback loop to determine the fate of the shoot apical meristem. These findings provide novel insights into the roles of Dt1 and FT5 a in controlling the stem growth habit and flowering time in soybean, which determine the adaptability and grain yield of this important crop. | Lin Yue Xiaoming Li Chao Fang Liyu Chen Hui Yang Jie Yang Zhonghui Chen Haiyang Nan Linnan Chen Yuhang Zhang Haiyang Li Xingliang Hou Zhicheng Dong James LWeller Jun Abe Baohui Liu Fanjiang Kong | 2021 | Journal of Integrative Plant Biology2021，63，6： | 3 |
| 13 | Deformation and failure characteristics of sandstone under uniaxial compression using distributed fiber optic strain sensing显示文摘This paper investigates the deformation and fracture propagation of sandstone specimen under uniaxial compression using the distributed fiber optic strain sensing(DFOSS)technology.It shows that the DFOSS-based circumferential strains are in agreement with the data monitored with the traditional strain gage.The DFOSS successfully scans the full-field view of axial and circumferential strains on the specimen surface.The spatiotemporal strain measurement based on DFOSS manifests crack closure and elastoplastic deformation,detects initialization of microcrack nucleation,and identifies strain localization within the specimen.The DFOSS well observes the effects of rock heterogeneity on rock deformation.The advantage of DFOSS-based strain acquisition includes the high spatiotemporal resolution of signals and the ability of full-surface strain scanning.The introduction to the DFOSS technology yields a better understanding of the rock damage process under uniaxial compression. | Lingfan Zhang Duoxing Yang Zhonghui Chen Aichun Liu | 2020 | Journal of Rock Mechanics and Geotechnical Engineering2020，12，5： | 3 |
| 14 | Effects of Low Protein Diets Supplemented with Ami-no Acids on Production Performance,Carcass Qual-ity and Input-output Ratio of Pigs显示文摘[Objectives] To study the effects of low-protein diets supplemented with amino acids on the production performance,carcass quality and input-output ratio of fattening pigs and growing-finishing pigs. [Methods] Two studies were conducted on fattening pigs and growing pigs respectively. Pigs in two experimental groupswere fed with low-protein diets supplemented with amino acids and normal diets respectively,and the initial weight,final weight,feed consumption and carcass index of the tested pigs were measured.[Results]The average final weight of fattening pigs in test group was 2. 4 kg lower than that in control group,while the difference was not significant( P > 0. 05). The average daily gain of fattening pigs in test group was 60 g lower than that in control group,indicating that low protein diets had a tendency to decrease the growth rate( P > 0. 05),and reduction of daily weight gain in low protein diet pigs reached 7. 6%. The development of pigs in low protein diet group was poor,however,the difference was not significant. Carcass backfat thickness in low-protein diet group was slightly higher than that in control group,the difference was significant( P < 0. 05). There was no significant difference in input-output ratio between low-protein diet group and control group.Finalweight of growing-finishing pigs in low-protein diet group was 3. 22 % lower than that in control group,the average daily weight gainwas 6. 91% lower than that in control group,feed intake in test group was 5. 48% lower than that in control group,and difference between the two treatments was significant( P < 0. 05). Feed meat ratio in low-protein diet group improved,however,the difference was not significant( P > 0. 05).[Conclusions]Production performance of the pigs would be decreasedand the input-output ratio could not be improvedwhen the adding contents of crude protein in diets was reduced 3%-4%. Therefore,it is recommended that the crude protein level should be enough when pigs were fed with low-protein diets. | Cui Jiajun Zhang Heliang Zhang Di Jin Jianhu Li Zhonghui | 2017 | Animal Husbandry and Feed Science2017，9，1： | 3 |
| 15 | Fast screening compositions of PM2.5 by ATR-FTIR: Comparison with results from IC and OC/EC analyzers显示文摘Chemical speciation of fine particles or PM_(2.5) collected on filters is still a costly and timeconsuming task. In this study, filter-based PM_(2.5) samples were collected during November–December 2013 at four sites in Guangzhou, and the major components were fast screened(~7 min per filter sample) by Attenuated Total Reflectance(ATR)-Fourier Transform Infrared Spectroscopic(FTIR) in comparison with that measured by Organic carbon/Element carbon(OC/EC) analyzer and Ion Chromatography(IC). The concentrations of nitrate, ammonium, sulfate,primary organic carbon(POC) and secondary organic carbon(SOC) measured by OC/EC and IC analyzers were better correlated with their infrared absorption peak heights at 1320 cm^(-1) for nitrate, 1435, 3045 and 3215 cm^(-1) for ammonium, 615 cm^(-1) for sulfate, 690, 760 and 890 cm^(-1) for POC and 1640 and 1660 cm^(-1) for SOC respectively, during polluted days(PM_(2.5)> 75 μg/m^3) than during clean days(PM_(2.5)≤ 75 μg/m^3). With the evolution of a haze episode during our field campaign, the concentrations of the major PM_(2.5) components displayed consistent variations with their infrared absorption peak heights, suggesting ATR-FTIR could be a fast and useful technique to characterize filter-based PM_(2.5) compositions particularly during pollution events although cautions should be taken when PM_(2.5) levels are low. Notably, elevated PM_(2.5) mass concentrations occurred with enhanced ratios of [NO_(-3)]/[SO_4^(2-)] and [NH^(+4)]/[SO_4^(2-)], implying that nitrogenous components play vital roles in the PM_(2.5) pollution events in the study region. | Xu Yu Wei Song Qingqing Yu Sheng Li Ming Zhu Yanli Zhang Wei Deng Weiqiang Yang Zhonghui Huang Xinhui Bi Xinming Wang | 2018 | Journal of Environmental Sciences2018，30，9： | 2 |
| 16 | Gaseous hydrogen storage properties of Mg-Y-Ni-Cu alloys prepared by melt spinning显示文摘For purpose of promoting the hydrogen absorption and desorption thermodynamics and kinetics properties of Mg-Ni-based alloys, partially substituting Y and Cu for Mg and Ni respectively and melt spinning technique were applied for getting Mg25-xYxNi9 Cu(χ = 0-7) alloys. Their microstructures and phases were characterized with the help of X-ray diffraction and transmission electron microscopy. Their hydrogen absorbing and desorbing properties were tested by a Sievert apparatus, DSC, and TGA, which were connected with a H2 detector. In order to estimate the dehydrogenation activation energy of alloy hydride, both Arrhenius and Kissinger methods were applied for calculation. It is found that their hydriding kinetics notably declines, however, their hydrogen desorption kinetics conspicuously improves, with spinning rate and Y content increasing. Their hydrogen desorption activation energy markedly decreases under the same constraint, and it is found that melt spinning and Y substituting Mg improve the real driving force for dehydrogenation. As for the tendency of hydrogen absorption capacity,it presents an elevation firstly and soon after a decline with the rising of spinning rate, however, it always lowers with Y content growing. With Y content and spinning rate increasing, their thermodynamic parameters(△H and △S absolute values) visibly decrease, and the starting hydrogen desorption temperatures of alloy hydrides obviously lower. | Yanghuan Zhang Yaqin Li Wei Zhang Zeming Yuan Zhonghui Hou Yan Qi Shihai Guo | 2019 | Journal of Rare Earths2019，37，7： | 2 |
| 17 | Regulating electronic structure of two-dimensional porous Ni/Ni_(3)N nanosheets architecture by Co atomic incorporation boosts alkaline water splitting显示文摘Interfacial engineering is a powerful method to improve the bifunctional electrocatalytic performance of pure phase catalysts.While it is expected to further optimize the electronic configuration of heterojunctions to boost the reaction kinetics in hydrogen/oxygen evolution reaction(HER/OER),but remains a challenge.Herein,a novel in situ hybrid heterojunction strategy is developed to construct 2D porous Co-doped Ni/Ni_(3)N heterostructure nanosheets(Co-Ni/Ni_(3)N)by pyrolysis of partially cobalt substituted nickel-zeolitic imidazolate framework(CoNi-ZIF)nanosheets under NH3 atmosphere.A combined experimental and theoretical studies manifest that the hybrid heterostructures can display regulative electronic states and downshift d-band center from the Fermi level,as well as optimize the adsorption energy of reaction intermediates,thus reducing the thermodynamic energy barriers and accelerating the catalytic kinetics.Consequently,benefitting from the optimized electronic configuration,hierarchical hollow nanosheets architecture,and abundant doped heterojunctions,the hybrid Co-Ni/Ni_(3)N heterostructure catalyst exhibits efficient catalytic activity for both HER(60 mV)and OER(322 mV)at 10 mA cm^(-2)in alkaline media,which is 105 and 47 mV lower than that of pure Ni_(3)N,respectively.The electrochemically active surface area of Co-Ni/Ni_(3)N is two times higher than that of Ni3N.Furthermore,the coupled practical water electrolyzer requires a low voltage of 1.575 V to reach 10 mA cm^(-2),and it can be driven by a 1.5 V battery.This work highlights the interface engineering guidance for the rational establishment of hybrid interfaces by electronic modulation of interfacial effect for alkaline water splitting. | Kaixi Wang Yingying Guo Zhonghui Chen Donghai Wu Shouren Zhang Baocheng Yang Jianan Zhang | 2022 | InfoMat2022，4，6： | 1 |
| 18 | GW112, a novel antiapoptotic protein that promotes tumor growth 显示文摘 | Zhang Xiuwu Huang Qian Yang Zhonghui | 2004 | Cancer Res2004，64，7： | 1 |
| 19 | A large insert Thellungiella halophila BIBAC library for genomics and identification of stress tolerance genes显示文摘 | Weiquan Wang Yaorong Wu Yin Li Jiaying Xie Zhonghui Zhang Zhiyong Deng Yiyue Zhang Cuiping Yang Jianbin Lai Huawei Zhang Hongyan Bao Sanyuan Tang Chengwei Yang Peng Gao Guixian Xia Huishan Guo Qi Xie | 2010 | Plant Molecular Biology (-)2010，，1： | 1 |
| 20 | OGG1 inhibition suppresses African swine fever virus replication显示文摘African swine fever virus(ASFV)is an important pathogen that causes a highly contagious and lethal disease in swine,for which neither a vaccine nor treatment is available.The DNA repair enzyme 8-oxoguanine DNA glycosylase 1(OGG1),which excises the oxidative base lesion 8-oxo-7,8-dihydroguanine(8-oxoG),has been linked to the pathogenesis of different diseases associated with viral infections.However,the role of OGG1-base excision repair(BER)in ASFV infection has been poorly investigated.Our study aimed to characterize the alteration of host reactive oxygen species(ROS)and OGG1 and to analyse the role of OGG1 in ASFV infection.We found that ASFV infection induced high levels and dynamic changes in ROS and 8-oxoG and consistently increased the expression of OGG1.Viral yield,transcription level,and protein synthesis were reduced in ASFV-infected primary alveolar macrophages(PAMs)treated by TH5487 or SU0268 inhibiting OGG1.The expression of BER pathway associated proteins of ASFV was also suppressed in OGG1-inhibited PAMs.Furthermore,OGG1 was found to negatively regulate interferonβ(IFN-β)production during ASFV infection and IFN-βcould be activated by OGG1 inhibition with TH5487 and SU0268,which blocked OGG1 binding to 8-oxoG.Additionally,the interaction of OGG1 with viral MGF360-14-L protein could disturb IFN-βproduction to further affect ASFV replication.These results suggest that OGG1 plays the crucial role in successful viral infection and OGG1 inhibitors SU0268 or TH5487 could be used as antiviral agents for ASFV infection. | Jie Fan Xinqian Lv Saixia Yang Shuxian Geng Jifei Yang Yaru Zhao Zhonghui Zhang Zhijie Liu Guiquan Guan Jianxun Luo Qiaoying Zeng Hong Yin Qingli Niu | 2023 | Virologica Sinica2023，38，1： | 1 |
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