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| 1 | Ultra-sensitive graphene strain sensor for sound signal acquisition and recognition显示文摘为健全信号获得和识别的一个便携、高精确的传感器从编织的特殊设计的 graphene 的薄电影被制作织物(GWF ) 。在被拉长之上,随机的裂缝的高密度出现在网络,它减少当前的小径,从而增加电阻。因此,这部电影能对人的喉咙作为一个紧张传感器起作用以便测量通过肌肉运动,一个声音是否被生产的讲话。超离频敏感允许由提取声波的签名特征的快速、低频率的讲话采样的实现。在这研究, 26 封英语信,典型汉字和音调的代表性的信号,甚至短语和句子被测试,揭示在电阻的明显、典型的变化。而且, graphene 传感器的电阻变化与预告录下的声音完美地反应了。由把人工智能与数字信号处理相结合,我们期望以后,这个 graphene 传感器将能成功地达成复杂声学的系统和听觉的数据的大数量。 | Yan Wang Tingting Yang Junchao Lao Rujing Zhang Yangyang Zhang Miao Zhu Xiao Li Xiaobei Zang Kunlin Wang Wenjian YU Hu Jin Li Wang Hongwei Zhu | 2015 | Nano Research2015，8，5： | 8 |
| 2 | Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms显示文摘The infusion of coronavirus disease 2019(COVID-19)patients with mesenchymal stem cells(MSCs)potentially improves clinical symptoms,but the underlying mechanism remains unclear.We conducted a randomized,single-blind,placebo-controlled(29 patients/group)phase II clinical trial to validate previous findings and explore the potential mechanisms.Patients treated with umbilical cord-derived MSCs exhibited a shorter hospital stay(P=0.0198)and less time required for symptoms remission(P=0.0194)than those who received placebo.Based on chest images,both severe and critical patients treated with MSCs showed improvement by day 7(P=0.0099)and day 21(P=0.0084).MSC-treated patients had fewer adverse events.MSC infusion reduced the levels of C-reactive protein,proinflammatory cytokines,and neutrophil extracellular traps(NETs)and promoted the maintenance of SARS-CoV-2-specific antibodies.To explore how MSCs modulate the immune system,we employed single-cell RNA sequencing analysis on peripheral blood.Our analysis identified a novel subpopulation of VNN2+hematopoietic stem/progenitorlike(HSPC-like)cells expressing CSF3R and PTPRE that were mobilized following MSC infusion.Genes encoding chemotaxis factors—CX3CR1 and L-selectin—were upregulated in various immune cells.MSC treatment also regulated B cell subsets and increased the expression of costimulatory CD28 in T cells in vivo and in vitro.In addition,an in vivo mouse study confirmed that MSCs suppressed NET release and reduced venous thrombosis by upregulating kindlin-3 signaling.Together,our results underscore the role of MSCs in improving COVID-19 patient outcomes via maintenance of immune homeostasis. | Rongjia Zhu Tingdong Yan Yingmei Feng Yan Liu Hongcui Cao Gongxin Peng Yanlei Yang Zhen Xu Jingqi Liu Wei Hou Xiaoyue Wang Zhe Li Luchan Deng Shihua Wang Jing Li Qin Han Hongling Li Guangliang Shan Yinghao Cao Xingyan An Jianshe Yan Zhonghui Zhang Huafei Li Xuebin Qu Jiaqi Zhu Shumin Zhou Jiao Wang Fengchun Zhang Jinming Gao Ronghua Jin Dayong Xu Yan-Qing Ma Tao Huang Shuang Peng Zhi Zheng Ilia Stambler Eric Gilson Lee Wei Lim Alexey Moskalev Antonio Cano Sasanka Chakrabarti Brun Ulfhake Huanxing Su Haoying Xu Sihuan Xu Feng Wei Holly MBrown-Borg Kyung-Jin Min Georgina Ellison-Hughes Calogero Caruso Kunlin Jin Robert Chunhua Zhao | 2021 | Cell Research2021，31，12： | 5 |
| 3 | KB4Rec:A Data Set for Linking Knowledge Bases with Recommender Systems显示文摘To develop a knowledge-aware recommender system,a key issue is how to obtain rich and structured knowledge base(KB)information for recommender system(RS)items.Existing data sets or methods either use side information from original RSs(containing very few kinds of useful information)or utilize a private KB.In this paper,we present KB4Rec v1.0,a data set linking KB information for RSs.It has linked three widely used RS data sets with two popular KBs,namely Freebase and YAGO.Based on our linked data set,we first preform qualitative analysis experiments,and then we discuss the effect of two important factors(i.e.,popularity and recency)on whether a RS item can be linked to a KB entity.Finally,we compare several knowledge-aware recommendation algorithms on our linked data set. | Wayne Xin Zhao Gaole He Kunlin Yang Hongjian Dou Jin Huang Siqi Ouyang Ji-Rong Wen | 2019 | Data Intelligence2019，1，2： | 3 |
| 4 | Endogenous Neural Stem Cells in the Adult Brain显示文摘 | Kunlin Jin Veronica Galvan | 2007 | Journal of Neuroimmune Pharmacology2007，，3： | 1 |
| 5 | Directed migration of neuronal precursors into the ischemic cerebral cortex and striatum显示文摘 | Kunlin Jin Yunjuan Sun Lin Xie Alyson Peel Xiao Ou Mao Sophie Batteur David A Greenberg | 2003 | Molecular and Cellular Neuroscience2003，，1： | 1 |
| 6 | Neuroglobin is up-regulated by and protects neurons from hypoxic-ischemic injury显示文摘 | YUN JUAN SUN KUNLIN JIN XIAO OU MAO | 2001 | Proc Natl Acad Sci USA2001，98，15： | 1 |
| 7 | Increased hippocampal neurogenesis in Alzheimer's disease显示文摘 | Jin Kunlin Alyson L Peel Xiao Ou Mao | 2004 | Proc Natl Acad Sci USA2004，101，1： | 1 |
| 8 | Neuroglobin protects the brain from experimental stroke in vivo 显示文摘 | Yunjuan Sun Kunlin Jin Alyson Peel | 2003 | PNAS2003，100，6： | 1 |
| 9 | Estrogen, Neuroprotection and Neurogenesis after Ischemic Stroke显示文摘 | Bei Shao Yifan Cheng Kunlin Jin | 2012 | Current Drug Targets2012，，2： | 1 |
| 10 | Hypoxia-inducible factor-1 and neuroglobin expression显示文摘 | Bryan Haines Marco Demaria Xiao Mao Lin Xie Judith Campisi Kunlin Jin David A. Greenberg | 2012 | Neuroscience Letters2012，，2： | 1 |
| 11 | Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia显示文摘 | Chen Jun Nagayama T Jin Kunlin | 1998 | J Neurosci1998，18，13： | 1 |
| 12 | Induction of Caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia显示文摘 | Jun Chen Tetsuya Nagayama Kunlin Jin | 1998 | J neurosci1998，18，13： | 1 |
| 13 | Neuronal nitric oxide synthase and ischemia-induced neurogenesis 显示文摘 | Sun Yunjuan Jin Kunlin Childs JT | 2005 | J Cereb Blood Flow Metab2005，25，： | 1 |
| 14 | Induction of Caspase-3 like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia显示文摘 | Jun Chen Tetsuya Nagayama Kunlin Jin | 1998 | J Neuroscience1998，18，13： | 1 |
| 15 | Early detection of DNA strand breaks in the brain after transient focal ischemia:implications for the role of DNA damage in apoptosis and neuronal cell death显示文摘 | Chen Jun Jin Kunlin Chen Minzhi | | 0，，01： | 1 |
| 16 | Neuroglobin protects the brain from experimental stroke in vivo显示文摘 | YUNJUAN SUN KUNLIN JIN ALYSON PEEL | 2003 | PNAS2003，100，6： | 1 |
| 17 | Neuroglobin:an endogenous neuroprotectant显示文摘 | David A Greenberg Kunlin Jin Adil A Khan | 2008 | Current Opinion in Pharmacology2008，8，： | 1 |
| 18 | Neuroglobin is up-regulated by and protects neurons from hypoxic-ischemic injury显示文摘 | SUN YUNJUAN JIN KUNLIN MAO XIAOOU | 2001 | Proc Natl Acad Sci USA2001，98，15： | 1 |
| 19 | Proliferative capacity of stem/progenitor-like cells in the kidney may associate with the outcome of patients with acute tubular necrosis显示文摘 | Youxin Ye Bingyin Wang Xinxin Jiang Weiming Hu Jian Feng Hua Li Mei Jin Yingjuan Ying Wenjuan Wang XiaoOu Mao Kunlin Jin | 2011 | Human Pathology2011，，8： | 1 |
| 20 | VEGF-induced neuroprotection,neurogenesis,and angiogenesis after focal cerebral ischemia显示文摘 | Yunjuan Sun Kunlin Jin Lin Xie | 2003 | Clin Invest2003，111，12： | 1 |
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