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| 1 | PBL:教育实践和研究的未来挑战显示文摘本文是一篇有关PBL的评论性研究,根据现代学习理论,作者论述了四个有关学习的原则,解释了这些原则在PBL中的应用,并对已进行的研究进行了评议。 | Diana HJM Dolmans Willem De Grave Ineke HAP Wolfhagen Cees PM van der Vleuten 梅人朗 | 2008 | 复旦教育论坛2008，6，1： | 44 |
| 2 | Problem‐based learning: future challenges for educational practice and research显示文摘 | Diana H J MDolmans WillemDe Grave Ineke H A PWolfhagen Cees P MVan Der Vleuten | 2005 | Medical Education2005，，7： | 4 |
| 3 | Oral polymorphonuclear neutrophil characteristics in relation to oral health: a cross-sectional, observational clinical study显示文摘Polymorphonuclear neutrophils(PMNs) have a major role in the innate immune system. However, little is known about PMN contribution in relation to oral health. The objective of this study was to investigate the numbers and functional characteristics of oral PMNs(o PMNs) compared with circulatory PMNs(c PMNs). Oral rinse and venous blood samples were obtained from 268 systemically and orally healthy volunteers in a cross-sectional observational study. PMN counts, cell cycle analysis and cellular activation state were investigated. Also, reactive oxygen species(ROS) production was analyzed, with and without bacterial stimulation(Fusobacterium nucleatum). In males, 1.2 × 10~6± 1.0 × 10~6 oPMNs were collected, and showed a tendency to correlate with the levels of gingival bleeding(r = 0.215, P = 0.008). Comparable o PMNs counts were found among females(1.0 × 10~6± 0.7 × 10~6). More late-stage apoptotic/necrotic cells were found among the o PMNs(53.1%) compared with the c PMNs(8.5%; Po0.001). Without additional stimulation, o PMNs were more activated than c PMNs, as indicated by higher expression of CD11 b, CD63 and CD66 b, and higher constitutive ROS levels(Po0.001). Notably, in response to bacterial stimulation, o PMNs released comparable ROS levels as c PMNs(P = 0.042). In conclusion, this study provides data on viable o PMNs showing high levels of activation in orally and systemically healthy individuals, free of apparent caries lesions and periodontal disease. These data suggests that although the o PMNs are in a more mature stage of their life cycle compared with the c PMNs, o PMNs are still responsive to stimulation, which indicates their functional potential and possible contribution to a healthy oral ecosystem. | Patrick Rijkschroeff Ineke DC Jansen Fridus A van der Weijden Bart IF Keijser Bruno G Loos Elena A Nicu | 2016 | International Journal of Oral Science2016，8，3： | 2 |
| 4 | Salpingotomy versus salpingectomy in women with tubal pregnancy (ESEP study): an open-label, multicentre, randomised controlled trial显示文摘 | Femke Mol Norah M van Mello Annika Strandell Karin Strandell Davor Jurkovic Jackie Ross Kurt T Barnhart Tamer M Yalcinkaya Harold R Verhoeve Giuseppe C M Graziosi Carolien A M Koks Ingmar Klinte Lars Hogstr?m Ineke C A H Janssen Harry Kragt Annemieke Hoek | 2014 | The Lancet2014，，： | 2 |
| 5 | How does the corpus callosum mediate interhemispheric transfer? A review显示文摘 | Lisette J. van der Knaap Ineke J.M. van der Ham | 2011 | Behavioural Brain Research2011，，1： | 2 |
| 6 | What is the differ- ence between IgA nephropathy and Henoch-Schonlein purpura nephritis 显示文摘 | Jean Claude Davin Ineke J Ten Berge | 2001 | Kidney Int2001，59，3： | 1 |
| 7 | Problem-based learning:future challenges for educational practice and research显示文摘 | Diana HJM Dolmans Willem De Grave Ineke HAP Wolfhagen | 2005 | Medical Education2005，，39： | 1 |
| 8 | The Development and Validation of A Framework for Teaching Compe- tencies in Higher Education显示文摘 | DINEKE E H DIANAH J M INEKE H P | 2004 | Higher Education2004，48，2： | 1 |
| 9 | A Gastric Diverticulum Containing Pancreatic Tissue and Presenting as Congenital Double Pylorus: Case Report and Review of the Literature显示文摘 | Victorien M. Wolters Peter G. J. Nikkels David C. Van Der Zee Peter P. G. Kramer Jan E. A. R. De Schryver Ineke G. M. Reijnen Roderick H. J. Houwen | 2001 | Journal of Pediatric Gastroenterology and Nutrition2001，，1： | 1 |
| 10 | Problem-based learning:future challenges for educational practice and research显示文摘 | Diana HJM Dolmans Willem De Grave Ineke HAP Wolfhagen | 2005 | Medical Education2005，，39： | 1 |
| 11 | Resolving CO2 and methane hydrate formation kinetics显示文摘 | Michael Golombok Erik Ineke Juan-Carlos Rojas Luzardo Yuan Yuan He Pacelli Zitha | 2009 | Environmental Chemistry Letters2009，，4： | 1 |
| 12 | The development and validation of a frame work for teaching competeneies in higher edueation显示文摘 | DINEKE E H Tigelaar DIANA H J M Dolmans INEKE H A P Wolfhagen | 2004 | Higher Education2004，48，2： | 1 |
| 13 | Problem-based learning:future challenges for educational practice and research显示文摘 | Diana HJM Dolmans Willem De Grave Ineke HAP Wolfhagen | 2005 | Medical Education2005，39，7： | 1 |
| 14 | Problem-based learning:future challenges for educational practice and research显示文摘 | Diana HJM Dolmans Willem De Grave Ineke HAP Wolfhagen | 2005 | Medical Education2005，39，7： | 1 |
| 15 | Influence of Daphnia infochemicals on functional traits of Microcystis strains (Cyanobacteria)显示文摘 | Ineke Gremberghe Pieter Vanormelingen Katleen Gucht Antoniya Mancheva Sofie D’hondt Luc Meester Wim Vyverman | 2009 | Hydrobiologia2009，，1： | 1 |
| 16 | Physics teachers’ conceptions of learning, teaching and professional development显示文摘 | Ineke Huibregtse Fred Korthagen Theo Wubbels | 1994 | International Journal of Science Education1994，，5： | 1 |
| 17 | What is the difference between IgA nephropathy and Henoch-Schonlein purpura nephritis显示文摘 | Jean-Claude Davin Ineke J Ten Berge | 2001 | Kidney Int2001，59，3： | 1 |
| 18 | The Effect of Interaction in Acquiring the Grammar of a Second Language显示文摘 | Folkert K Ineke V | 2002 | International Journal of Educational Research2002，，37： | 1 |
| 19 | The relation between adolescent suicidal behavior and life events in childhood and adolescence显示文摘 | Erik J Ineke C Rene F | 1992 | Am J Psychiatry1992，149，1： | 1 |
| 20 | A Randomized Clinical Trial of Intermittent Subglottic Secretion Drainage in Patients Receiving Mechanical Ventilation显示文摘 | KEES SMULDERS HANS VAN DER HOEVEN INEKE WEERS-POTHOFF | 2002 | Chest2002，121，3： | 1 |
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