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| 1 | High-intensity focused ultrasound ablation:An effective bridging therapy for hepatocellular carcinoma patients显示文摘AIM:To analyze whether high-intensity focused ultrasound(HIFU) ablation is an effective bridging therapy for patients with hepatocellular carcinoma(HCC).METHODS:From January 2007 to December 2010,49 consecutive HCC patients were listed for liver transplantation(UCSF criteria).The median waiting time for transplantation was 9.5 mo.Twenty-nine patients received transarterial chemoembolization(TACE) as a bringing therapy and 16 patients received no treatment before transplantation.Five patients received HIFU ablation as a bridging therapy.Another five patients with the same tumor staging(within the UCSF criteria) who received HIFU ablation but not on the transplant list were included for comparison.Patients were comparable in terms of Child-Pugh and model for end-stage liver disease scores,tumor size and number,and cause of cirrhosis.RESULTS:The HIFU group and TACE group showed no difference in terms of tumor size and tumor number.One patient in the HIFU group and no patient in the TACE group had gross ascites.The median hospital stay was 1 d(range,1-21 d) in the TACE group and two days(range,1-9 d) in the HIFU group(P < 0.000).No HIFU-related complication occurred.In the HIFU group,nine patients(90%) had complete response and one patient(10%) had partial response to the treatment.In the TACE group,only one patient(3%) had response to the treatment while 14 patients(48%) had stable disease and 14 patients(48%) had progressive disease(P = 0.00).Seven patients in the TACE group and no patient in the HIFU group dropped out from the transplant waiting list(P = 0.559).CONCLUSION:HIFU ablation is safe and effective in the treatment of HCC for patients with advanced cirrhosis.It may reduce the drop-out rate of liver transplant candidate. | Tan To Cheung Sheung Tat Fan See Ching Chan Kenneth SH Chok Ferdinand SK Chu Caroline R Jenkins Regina CL Lo James YY Fung Albert CY Chan William W Sharr Simon HY Tsang Wing Chiu Dai Ronnie TP Poon Chung Mau Lo | 2013 | World Journal of Gastroenterology2013，19，20： | 23 |
| 2 | Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS显示文摘 | Simon P Dunlop David Jenkins Keith R Neal Robin C Spiller | 2003 | Gastroenterology2003，，6： | 2 |
| 3 | relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious ibs 显示文摘 | simon p dunlop davaid jenkins keith rneal | 2003 | gastroenterlogy2003，125，6： | 1 |
| 4 | Evidence that Soil Carbon Pool Determines Susceptibility of Semi-Natural Ecosystems to Elevated Nitrogen Leaching显示文摘 | Christopher D. Evans Brian Reynolds Alan Jenkins Rachel C. Helliwell Christopher J. Curtis Christine L. Goodale Robert C. Ferrier Bridget A. Emmett Michael G. Pilkington Simon J. M. Caporn Jacky A. Carroll David Norris Jennifer Davies Malcolm C. Coull | 2006 | Ecosystems2006，，3： | 1 |
| 5 | 互联让我们不再对话了么显示文摘 | Simon Jenkins | 2012 | 投资者报2012，，22： | 1 |
| 6 | 'Paying for the Arts'显示文摘 | | 1984 | Economics1984，，： | 1 |
| 7 | Real-time quantitative PCR for analysis of candidate fungal biopesticides against malaria: Technique validation and first applications显示文摘 | Andrew S Bell Simon Blanford Nina Jenkins | 2009 | J Invertebr Pathol2009，100，3： | 1 |
| 8 | Timing Accuracy and Decision Time in High-speed Ball Games显示文摘 | McLEOD PETER JENKINS SIMON | 1991 | Int J Sport Psy1991，22，34： | 1 |
| 9 | Islets of Langerhans from prohormone convertase‐2 knockout mice show α‐cell hyperplasia and tumorigenesis with elevated α‐cell neogenesis显示文摘 | Huw B. Jones Jaimini Reens Simon R. Brocklehurst Catherine J. Betts Sue Bickerton Alison L. Bigley Richard P. Jenkins Nicky M. Whalley Derrick Morgan David M. Smith | 2014 | Path2014，，1： | 1 |
| 10 | Evidence that Soil Carbon Pool Determines Susceptibility of Semi-Natural Ecosystems to Elevated Nitrogen Leaching显示文摘 | Christopher D. Evans Brian Reynolds Alan Jenkins Rachel C. Helliwell Christopher J. Curtis Christine L. Goodale Robert C. Ferrier Bridget A. Emmett Michael G. Pilkington Simon J. M. Caporn Jacky A. Carroll David Norris Jennifer Davies Malcolm C. Coull | 2006 | Ecosystems2006，，3： | 1 |
| 11 | Sequence and analysis ofchromosome 3 of the plant Arabidopsis thaliana显示文摘 | Salanoubat M Lemcke K Rieger M Ansorge W Unseld M Fartmann B Vaile G Blocker H Pcrez-Alonso M Obennaier B Delseny M Boutry M Grivell L A Mache R Puigdomenech P De Simone V Choisne N Artiguenave F Robert C Brottier P Wincker P Cattolico L Weissenbach J Saurin W Quetier F Schafer M Mu||er-Auer S Gabel C Fuchs M Benes V Wurmbach E Drzonek H Erfle H Jordan N Bangert S Wiedelmann R Kranz H Voss H Holland R Brandt P Nyakatura G Vezzi A D' Angelo M Pallavicini A Toppo S Simionati B Conrad A Homischer K Kauer G Lohnert T H Nordsiek G Reichelt J Scharfe M Schon O Bargues M Terol J Climent J Navarro P CoUado C Perez-Perez A Ottenwalder B Duchemin D Cooke R Laudie M Berger-Llauro C Pumelle B Masuy D de Haan M Maarse A C Alcaraz J P Cottet A Casacuberta E Monfort A Argiriou A Flores M Liguori R Vitale D Mannhaupt G Haase D Schoof H Rudd S Zaccaria P Mewes H W Mayer K F Kaul S Town C D Koo H L Tailon L J Jenkins J Rooney T Rizzo M Waits A Utterback T Fujii C Y Shea T P Creasy T H Haas B Maiti R Wu D Peterson J Van Aken S Pal G Militscher J Sellers P Gill J E Feldblyum T V Preuss D Lin X Nierman W C Salzberg S L White O Venter J C Fraser C M Kaneko T Nakamura Y Sato S Kato T Asamizu E Sasamoto S Kimura T Idesawa K Kawashiraa K Kishida Y Kiyokawa C Kohara M Matsumoto kl Matsuno A Muraki A Nakayama S Nakazaki N Shinpo S Takeuchi C Wada T Watanabe A Yamada M Yasuda M Tabata S | 2000 | Nature2000，408，6814： | 1 |
| 12 | 互联让我们不再对话了么显示文摘 | Simon Jenkins | 2012 | 投资者报2012，，22： | 1 |
| 13 | Evidencefor a new type of shears mechanism显示文摘 | Simons A J Wadsworth R Jenkins | 2003 | Physical ReviewLetters2003，91，16： | 1 |
| 14 | Lack of efficacy of a reduced microparticle diet in a multi-centred trial of patients with active Crohn?s disease显示文摘 | Miranda C.E. Lomer Stephen L. Grainger Roland Ede Adrian P. Catterall Simon M. Greenfield Russell E. Cowan F. Robin Vicary Anthony P. Jenkins Helen Fidler Rory S. Harvey Richard Ellis Alistair McNair Colin C. Ainley Richard P.H. Thompson Jonathan J. Powel | 2005 | European Journal of Gastroenterology & Hepatology2005，，3： | 1 |
| 15 | Building the new international science of the agriculture-food-water-environment Nexus in China and the world显示文摘The multiple,complex and systemic problems of the agriculture-food-water-environment nexus(“Nexus”)are among the most significant challenges of the 21st century.China is a key site for Nexus research amidst profound socio-environmental problems.The policy implications of these problems have been authoritatively summarized elsewhere.This study presents discussions at an international workshop in Guangzhou that asked instead“What science is needed to deliver the growing policy commitments regarding these challenges?And,What changes are needed to the science itself?”Understanding and effective intervention regarding the Nexus calls for a paradigm shift:to a new kind of science of(capacity for)international,interdisciplinary,and impactful research working with and within complex socio-natural systems.We here argue that science must become proactive in approach,striving only for“minimal harm”not“silver bullet”solutions,and adopting an explicitly long-term strategic perspective.Together,these arguments lead to calls for reorienting science and science policy in three ways:from short-term remediation to longer-term optimization;from a focus on environmental threats to one on the opportunities for international collaborative learning;and toward supporting new forms of scientific career.We bring these points together by recommending a new form of scientific institution:a global network of collaborative Nexus Centres,under the umbrella of a global Food Nexus Organization akin to those of the human genome and proteome. | Xinguang Zhu Martin Parry Yonglong Lu Matthew Heard Guangguo Ying Simon Vaughan Jianbo Shen Alan Jenkins Yunpeng Wang Silvia Lacorte Tingping Ouyang Francisco Pedrero Salcedo Jun Niu John Quinton Chunling Luo Fusuo Zhang Gan Zhang William Davies Kevin Jones David Tyfield | 2016 | Ecosystem Health and Sustainability2016，2，11： | 0 |
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