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| 1 | Distribution of IgG galactosylation as a promising biomarker for cancer screening in multiple cancer types显示文摘 | Shifang Ren Zejian Zhang Congjian Xu Lin Guo Renquan Lu Yihong Sun Jianming Guo Ruihuan Qin Wenjun Qin Jianxin Gu | 2016 | Cell Research2016，26，8： | 8 |
| 2 | One Stone Four Birds:A Novel Liposomal Delivery System Multi-functionalized with Ginsenoside Rh2 for Tumor Targeting Therapy显示文摘Liposomes hold great potential in anti-cancer drug delivery and the targeting treatment of tumors.However,the clinical therapeutic efficacy of liposomes is still limited by the complexity of tumor microenvironment(TME)and the insufficient accumulation in tumor sites.Meanwhile,the application of cholesterol and polyethylene glycol(PEG),which are usually used to prolong the blood circulation and stabilize the structure of liposomes respectively,has been questioned due to various disadvantages.Herein,we developed a ginsenoside Rh2-based multifunctional liposome system(Rh2-lipo)to effectively address these challenges once for all.Different with the conventional’wooden’liposomes,Rh2-lipo is a much more brilliant carrier with multiple functions.In Rh2-lipo,both cholesterol and PEG were substituted by Rh2,which works as membrane stabilizer,long-circulating stealther,active targeting ligand,and chemotherapy adjuvant at the same time.Firstly,Rh2 could keep the stability of liposomes and avoid the shortcomings caused by cholesterol.Secondly,Rh2-lipo showed a specifically prolonged circulation behavior in the blood.Thirdly,the accumulation of the liposomes in the tumor was significantly enhanced by the interaction of glucose transporter of tumor cells with Rh2.Fourth,Rh2-lipo could remodel the structure and reverse the immunosuppressive environment in TME.When tested in a 4T1 breast carcinoma xenograft model,the paclitaxel-loaded Rh2-lipo realized high efficient tumor growth suppression.Therefore,Rh2-lipo not only innovatively challenges the position of cholesterol as a liposome component,but also provides another innovative potential system with multiple functions for anti-cancer drug delivery. | Chao Hong Jianming Liang Jiaxuan Xia Ying Zhu Yizhen Guo Anni Wang Chunyi Lu Hongwei Ren Chen Chen Shiyi Li Dan Wang Huaxing Zhan Jianxin Wang | 2020 | Nano-Micro Letters2020，12，10： | 8 |
| 3 | A Data-driven Motion Control Approach for a Robotic Fish显示文摘 | Qinyuan Ren Jianxin Xu Xuefang Li | 2015 | Journal of Bionic Engineering2015，12，3： | 5 |
| 4 | Dynamic network embedding via incremental skip-gram with negative sampling显示文摘Network representation learning,as an approach to learn low dimensional representations of vertices,has attracted considerable research attention recently.It has been proven extremely useful in many machine learning tasks over large graph.Most existing methods focus on learning the structural representations of vertices in a static network,but cannot guarantee an accurate and efficient embedding in a dynamic network scenario.The fundamental problem of continuously capturing the dynamic properties in an efficient way for a dynamic network remains unsolved.To address this issue,we present an efficient incremental skip-gram algorithm with negative sampling for dynamic network embedding,and provide a set of theoretical analyses to characterize the performance guarantee.Specifically,we first partition a dynamic network into the updated,including addition/deletion of links and vertices,and the retained networks over time.Then we factorize the objective function of network embedding into the added,vanished and retained parts of the network.Next we provide a new stochastic gradient-based method,guided by the partitions of the network,to update the nodes and the parameter vectors.The proposed algorithm is proven to yield an objective function value with a bounded difference to that of the original objective function.The first order moment of the objective difference converges in order of O(1/n^2),and the second order moment of the objective difference can be stabilized in order of O(1).Experimental results show that our proposal can significantly reduce the training time while preserving the comparable performance.We also demonstrate the correctness of the theoretical analysis and the practical usefulness of the dynamic network embedding.We perform extensive experiments on multiple real-world large network datasets over multi-label classification and link prediction tasks to evaluate the effectiveness and efficiency of the proposed framework,and up to 22 times speedup has been achieved. | Hao PENG Jianxin LI Hao YAN Qiran GONG Senzhang WANG Lin LIU Lihong WANG Xiang REN | 2020 | Science China(Information Sciences)2020，63，10： | 4 |
| 5 | Effect of the structure of ginsenosides on the in vivo fate of their liposomes显示文摘To utilize themultiple functions and give full play of ginsenosides,a variety of ginsenosides with different structures were prepared into liposomes and evaluated for their effect on the stability,pharmacokinetics and tumor targeting capability of liposomes.The results showed that the position and number of glycosyl groups of ginsenosides have significant effect on the in vitro and in vivo properties of their liposomes.The pharmacokinetics of ginsenosides liposomes indicated that the C-3 sugar group of ginsenosides is beneficial to their liposomes for longer circulation in vivo.The C-3 and C-6 glycosyls can enhance the uptake of their liposomes by 4T1 cells,and the glycosyls at C-3 position can enhance the tumor active targeting ability significantly,based on the specific binding capacity to Glut 1 expressed on the surface of 4T1 cells.According to the results in the study,ginsenoside Rg3 and ginsenoside Rh2 are potential for exploiting novel liposomes because of their cholesterol substitution,long blood circulation and tumor targeting capabilities.The results provide a theoretical basis for further development of ginsenoside based liposome delivery systems. | Chen Chen Jiaxuan Xia Hongwei Ren Anni Wang Ying Zhu Ru Zhang Zicheng Gan Jianxin Wang | 2022 | Asian Journal of Pharmaceutical Sciences2022，17，2： | 4 |
| 6 | Hydrothermal exfoliated molybdenum disulfide nanosheets as anode material for lithium ion batteries显示文摘Ultrathin MoS2nanosheets were prepared in high yield using a facile and effective hydrothermal intercalation and exfoliation route. The products were characterized in detail using X-ray diffraction, scanning electron microscopy, transmission electron microscopy and Raman spectroscopy. The results show that the high yield of MoS2nanosheets with good quality was successfully achieved and the dimensions of the immense nanosheets reached 1 μm–2 μm. As anode material for Li-ion batteries, the as-prepared MoS2nanosheets electrodes exhibited a good initial capacity of 1190 mAh g-1and excellent cyclic stability at constant current density of 50 mA g-1. After 50 cycles, it still delivered reversibly sustained high capacities of 750 mAh g-1. | Yundan Liu Long Ren Xiang Qi Liwen Yang Jun Li Yao Wang Jianxin Zhong | 2014 | Journal of Energy Chemistry2014，23，2： | 4 |
| 7 | A GIM-Based Biomimetic Learning Approach for Motion Generation of a Multi-Joint Robotic Fish显示文摘 | Qinyuan Ren Jianxin Xu Lupeng Fan Xuelei Niu | 2013 | Journal of Bionic Engineering2013，10，4： | 4 |
| 8 | Experimental Investigation on Microstructure and Segregation of Ultrahigh Strength Al-Zn-Mg-Cu-Zr-Sc-Ni Alloy during Homogenization显示文摘Ultrahigh strength Al-12Zn-2.4Mg-1.1Cu-0.20Zr-0.30Sc-0.30Ni alloy billets were fabricated by spray deposition method(the Osprey process). The effect of homogenization treatment on the microstructures and tensile properties were investigated by OM, SEM and EDS. The results show that adding small amount of Sc and Zr can greatly refine the grain size of the billet, with the average grain size of 10 μm. Grain-boundary becomes coarser firstly and then thinner under different homogenizing condition and grain coarsening were observed. The solute elements content of Zn inside grains has a peak at 490 ℃ /2 h, and Cu element, which was solved into matrix, can enhance the matrix hardness obviously during homogenization. The suitable homogenizing treatment is 460~490 °C/2 h for the hot extrusion of the studied alloy; after the optimized solid solution and T6 aging, the highest ultimate tensile strength (UTS) is 858 MPa with a ductility of 4.8%. | Li Zhenliang Xie Jianxin Chen Wei Zhai Jing Ren Huiping Wang Yufeng | 2009 | 稀有金属材料与工程2009，38，A03： | 3 |
| 9 | Locomotion Generation and Motion Library Design for an Anguilliform Robotic Fish显示文摘 | Xuelei Niu Jianxin Xu Qinyuan Ren Qingguo Wang | 2013 | Journal of Bionic Engineering2013，10，3： | 3 |
| 10 | Antibacterial Effects of Chinese Herbal Medicines against Streptococcus iniae in Oreochromis niloticus显示文摘In this study,the antibacterial effects of Chinese herbal medicines against Streptococcus iniae in Oreochromis niloticus were investigated by drug sensitivity test. The results indicated that Streptococcus iniae was extremely sensitive to Galla Chinensis,Fructus Hippophae and Fructus Mume,highly sensitive to Sappan Lignum,Pericarpium Granati,Folium Eucalypti and Radix Scutellariae,moderately sensitive to Rhizoma Coptidis,Radix et Rhizoma Rhei,Flos Caryophyllata,Cortex phellodendri and Rabdosia serra( Maxim.) Hara,and insensitive to Herba Portulacae,Herba Houttuyniae,Polygonum hydropiper L.,Herba Menthae,Radix Glycyrrhizae,Pericarpium Citri Reticulatae,Herba Andrographitis and Rhizoma Acori Tatarinowii. Chinese medicinal herbs which Streptococcus iniae was extremely sensitive or moderately sensitive to were selected and prepared into three Chinese herbal medicine formulae for medicated bath of Oreochromis niloticus infected artificially with Streptococcus iniae. The results showed that medicated bath elicited therapeutic effects on infected Oreochromis niloticus. Formula II exhibited the best therapeutic effect with an effective percentage of 90%. | Guisheng GAO Yanying ZHANG Yongmei SU Qiumei SHI Guangping GAO Yating BAI Hongsheng HAN Jianxin ZHU Qingchun SONG Guanglian REN | 2016 | Agricultural Biotechnology2016，5，1： | 2 |
| 11 | Oxygen Vacancy-Rich 2D TiO_(2) Nanosheets:A Bridge Toward High Stability and Rapid Hydrogen Storage Kinetics of Nano-Confined MgH_(2)显示文摘MgH_(2) has attracted intensive interests as one of the most promising hydrogen storage materials.Nevertheless,the high desorption temperature,sluggish kinetics,and rapid capacity decay hamper its commercial application.Herein,2D TiO_(2) nanosheets with abundant oxygen vacancies are used to fabricate a flower-like MgH_(2)/TiO_(2) heterostructure with enhanced hydrogen storage performances.Particularly,the onset hydrogen desorption temperature of the MgH_(2)/TiO_(2) heterostructure is lowered down to 180℃(295℃ for blank MgH_(2)).The initial desorption rate of MgH_(2)/TiO_(2) reaches 2.116 wt% min^(-1) at 300℃,35 times of the blank MgH_(2) under the same conditions.Moreover,the capacity retention is as high as 98.5% after 100 cycles at 300℃,remarkably higher than those of the previously reported MgH_(2)-TiO_(2) composites.Both in situ HRTEM observations and ex situ XPS analyses confirm that the synergistic effects from multi-valance of Ti species,accelerated electron transportation caused by oxygen vacancies,formation of catalytic Mg-Ti oxides,and stabilized MgH_(2) NPs confined by TiO_(2) nanosheets contribute to the high stability and kinetically accelerated hydrogen storage performances of the composite.The strategy of using 2D substrates with abundant defects to support nano-sized energy storage materials to build heterostructure is therefore promising for the design of high-performance energy materials. | Li Ren Wen Zhu Yinghui Li Xi Lin Hao Xu Fengzhan Sun Chong Lu Jianxin Zou | 2022 | Nano-Micro Letters2022，14，9： | 2 |
| 12 | Research on Accounting of Human Resources Development显示文摘 | Jianxin Cao Yanping Yang Ren Wang | 2005 | China-USA Business Review2005，4，4： | 2 |
| 13 | In- fluence of lubricant on the properties of poly(ether ether ketone) and poly(ether ether ketone)/carbon fiber composites 显示文摘 | Zhang Shuling Mu Jianxin Ren Dianfu | 2010 | Macromolecular Research2010，18，12： | 1 |
| 14 | Identifying pro- tein complexes based on density and modularity in protein- protein interaction network 显示文摘 | REN Jun WANG Jianxin LI Min | 2013 | BMC systems biology2013，7，4： | 1 |
| 15 | Crystal design of bismuth oxyiodide with highly exposed (110) facets on curved carbon nitride for the photocatalytic degradation of pollutants in wastewater显示文摘Crystalline materials with specific facet atomic arrangements and crystal facet structures exhibit unique functions according to their facet effects, quantum size effects and physical and chemical properties. In this study, a novel high-exposure (110) facet of bismuth oxyiodide (BiOI) was prepared (denoted as BiOI-110), and designed as nanosheets rich in oxygen vacancies by crystal facet design and regulation. Graphitic carbon nitride was designed as curved carbon nitride with dibromopyrazine, denoted as DCN, which contributed to a significant structural distortion in plane symmetry and improved the separation of charge carriers. Novel heterostructured BiOI-110/DCN nanosheets with a high-exposure (110) facet and abundant oxygen vacancies were successfully designed to enhance the photocatalytic degradation of organic pollutants. It was demonstrated that complete and tight contact between BiOI-110 and DCN was achieved by changing the size and crystal facet of BiOI. Oxytetracycline (OTC) and methyl blue dyes were used as targets for pollutant degradation, and 85.6% and 96.5% photocatalytic degradation efficiencies, respectively, were observed in the optimal proportion of 7% BiOI-110/DCN. The experimental results and electron spin resonance analysis showed that •O_(2)^(–) and h^(+) played a major role in the process of pollutant degradation. Additionally, high-resolution liquid chromatography-mass spectrography was used to identify the reaction intermediates of OTC, and the possible degradation pathway of this pollutant was proposed. Finally, the excellent reusability of BiOI-110/DCN nanomaterials was confirmed, providing a new approach for the removal of antibiotics that are difficult to biodegrade. Overall, crystal facet design has been proven to have broad prospects in improving the water environment. | Jianxin Chen Yupeng Li Jihui Li Jian Han Guijun Zhu Liang Ren | 2022 | Frontiers of Chemical Science and Engineering2022，16，7： | 1 |
| 16 | Modeling Productivity in Mangrove Forests as Impacted by Effective Soil Water Availability and Its Sensitivity to Climate Change Using Biome-BGC显示文摘 | Zhongkui Luo Osbert Jianxin Sun Enli Wang Hai Ren Hualin Xu | 2010 | Ecosystems2010，，7： | 1 |
| 17 | The effects of κ-casein polymorphism on the texture and functional properties of mozzarella cheese显示文摘 | Daxi Ren Bo Chen Youliang Chen Shuying Miao Jianxin Liu | 2013 | International Dairy Journal2013，，2： | 1 |
| 18 | β-Cyclodextrin carbon-based nanoparticles with a core-shell-shell structure for efficient adsorption of crystal violet and bisphenol A显示文摘Textile wastewater contains highly toxic,nondegradable,carcinogenic organic pollutants,causing severe damage to the ecological environment.In this work,β-cyclodextrin carbon-sphere-based nanocomposite(CS/SiO_(2)@β-CD)with a core-shell-shell configuration was prepared by hydrothermal synthesis and subsequent sedimentation-azeotropic distillation with SiO_(2)as intermediate layer for the removal of crystal violet(CV)and bisphenol A(BPA).The chemical structure and morphology of the CS/SiO_(2)@β-CD were characterized by FT-IR,SEM and TEM.The effects of contact time,pH,temperature and initial concentration of the absorbates on the adsorption property were explored.The CS/SiO_(2)@β-CD showed excellent adsorption capacity on CV and BPA,and the maximum adsorption capacity was 87.873 mg g^(-1)and 165.095 mg g^(-1),respectively.Their adsorption process was in line with the pseudo-second-order and pseudo-first-order kinetic models,respectively.The adsorption thermodynamics could be better fitted by Langmuir model than by Freundlich model.The calculated thermodynamic parameters(-ΔG0,ΔS0 andΔH0)illustrated the adsorption of CV was endothermic,in contrast,the adsorption of BPA was exothermic process.Furthermore,the CS/SiO_(2)@β-CD showed excellent recovery performance,making it a potential adsorbent for the practical treatment of textile wastewater. | Tian Tian Mengling Liu Yinhui Li Jian Han Liang Ren Heike Lorenz Qing Wu Jianxin Chen | 2022 | Particuology2022，20，3： | 1 |
| 19 | High-speed Stokes vector receiver enabled by a spin-dependent optical grating显示文摘Stokes vector direct detection is a promising,cost-effective technology for short-distance communication applications.Here,we design and fabricate a spin-dependent liquid crystal grating to detect light polarization states.By separating the circular and linear components of incident light,the polarization states can be resolved with accuracy of up to 0.25°.We achieved Stokes vector direct detection of quadrature phase-shift keying(QPSK),8 PSK,and16-ary quadrature amplitude modulation signals with 32,16,and 16 GBd rates,respectively.We integrated the system,including the grating,photodetectors,and optical elements,on a miniaturized printed circuit board and demonstrated high-speed optical communications with 16 GBd rate QPSK signals. | YOUPENG XIE TING LEI DAWEI WANG JIANXIN REN YANMENG DAI YANJUN CHEN LUPING DU BO LIU ZHAOHUI LI XIAOCONG YUAN | 2021 | Photonics Research2021，9，8： | 1 |
| 20 | The effects of κ-casein polymorphism on the texture and functional properties of mozzarella cheese显示文摘 | Daxi Ren Bo Chen Youliang Chen Shuying Miao Jianxin Liu | 2013 | International Dairy Journal2013，，2： | 1 |
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