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| 1 | Geological constraints of giant and medium-sized gas fields in Kuqa Depression显示文摘There is a gas-rich and well-charged petroleumsystem in the Kuqa Depression where Triassic and Jurassicsource rocks play important roles. Distributed in an area ofmore than 10000 km and with a thickness of up to 1000 m,they are composed of dark mudstones, carbonaceous mud-stones and coal seams containing 6%, 40% and 90% of TOC,respectively, and are mainly the humic organic matter. Ashigh-quality regional cap rocks, the Neogene and Eogenegypsum rocks and gypseous mudstones matched well withthe underlying Neogene and Cretaceous-Eogene sandstones.They have formed the most favorable reservoir-seal assem-blages in the Kuqa Depression. Also the Jurassic sandstonesand mudstones formed another favorable reservoir-seal as-semblage. The traps are shaped late in the fold-thrust belt,mainly fixed in the Tertiary-Quaternary, where ten structurestyles have been distinguished. These traps spread as a zonein N-S, are scattered like a segmental line in W-E and showtier-styled vertically. The best traps are gypsum-salt coveredfault-bend anticlines related to the passive roof duplex. Thispetroleum system is characterized by late accumulation. Inthe early Himalayan Movement, mainly gas condensate andoil accumulated and were distributed in the outer circularregion of the kitchen; whereas in the middle and late Hima-layan the gas accumulations mainly formed and were dis-tributed in the inner circular region near the kitchen. Theoverpressure of gas pools is common and is formed by sealcapacity of thick gypsum layers, extensive tectonic compres-sion and large uplift. The well-preserved anticline traps un-derlying the high-quality regional cap rocks of the Tertiarygypsum rocks and gypseous mudstones are the main targetsfor the discovery of giant and medium-sized gas fields. Aboveconclusions are important for the petroleum geology theoryand the exploration of the fold-thrust belt in foreland basinsin central and western China. | JIA Chengzao GU Jiayu ZHANG Guangya | 2002 | Chinese Science Bulletin2002，47，S1： | 17 |
| 2 | Ag nanoparticles sensitize IR-induced killing of cancer cells显示文摘 | Ruizhi Xu Jun Ma Xinchen Sun ZhongpingChen Xiaoli Jiang Zhirui auo Lan Huang YangLi Meng Wang Changling Wang Jiwei Liu XuFan Jiayu Gu Xi Chen Yu Zhang Ning Gu | 2009 | Cell Research2009，19，8： | 11 |
| 3 | Reservoir characteristics and genesis of high-porosity and high-permeability reservoirs in Tarim Basin显示文摘Based on detailed studies, this paper proposesthat in the Tarim Basin, hydrocarbon reservoirs widespreadeither in vertical sequences or in plane and high-porosity andhigh-permeability reservoirs are developed all over the basin.However, obvious difference and heterogeneity exist amongdifferent kinds of reservoirs. The lithologic characteristics,reservoir space types and reservoir properties in variousstrata have been probed. The result indicates that althoughthe Paleozoic carbonates have been deeply buried for a longperiod, high-quality reservoirs with the porosity of up to 5%-8% (12% as the maximum) and the permeability of10×10-3-100×10-3 μm2 (1000×10-3μm2 as the maximum)can be found in certain areas. These include the area withthe development of reefs and carbonate beaches, the weath-ered-crust buried-hill belts that have undergone thelong-term exposure, weathering and leaching, the area withthe development of dolomitization, and those areas that haveexperienced the resolution of carbonic acid and organic acidgenerated by the maturity of the organic matter. Finally, thegenesis of the high-porosity and high-permeability reservoirsin deep-buried conditions (with the depth more than 3500 m)have been investigated thoroughly. | GU Jiayu JIA Jinhua FANG Hui | 2002 | Chinese Science Bulletin2002，47，S1： | 7 |
| 4 | Cloning and functional characterization of Rht8,a“Green Revolution”replacement gene in wheat显示文摘Dear Editor,Wheat(Triticum aestivum)is a major staple crop in the world and provides~20%of the food calories for human consumption(Appels et al.,2018).During the 1960s and 1970s,the introduction of two semi-dwarfing genes Rht-B1b and Rht-D1b in wheat varieties strikingly improved lodging resistance and harvest index,and therefore substantially increased grain yield,resulting in the well-known'Green Revolution'(Peng et al.,1999).However,plants carrying Rht-B1b and Rht-D1b suffer from several drawbacks. | Hongchun Xiong Chunyun Zhou Meiyu Fu Huijun Guo Yongdun Xie Linshu Zhao Jiayu Gu Shirong Zhao Yuping Ding Yuting Li Jiazi Zhang Ke Wang Xuejun Li Luxiang Liu | 2022 | Molecular Plant2022，15，3： | 7 |
| 5 | Amphiphilic dextran/magnetite nanocomposites as magnetic resonance imaging probes显示文摘Superparamagnetic iron oxide (SPIO) nanoparticles are effective contrast agents for enhancement of magnetic resonance imaging at the tissue, cellular or even molecular levels. High quality SPIO nanoparticles can be synthesized in the organic phase but need to be transferred into water before any biomedical applications. In this study, amphiphilic poly(ε-caprolactone) grafted dextran (Dex-g-PCL) was used as carriers for particle encapsulation and stabilization in the aqueous phase. Multiple SPIO nanoparticles were self-assembled together with the help of Dex-g-PCL during phase transfer from chloroform to water, and diameters of Dex-g-PCL/SPIO nanocomposites were (64 ± 22) nm through dynamic light scattering measurement. These nanocomposites were superparamagnetic at 300 K with saturated magnetization of 88 emu/g Fe. In the magnetic field of 1.5 T, Dex-g-PCL/SPIO nanocomposites had a T2 relaxivity of 363 Fe mL·mol-1·s-1. This unique nanocomposite brought significant mouse liver contrast with signal intensity changes of -60% at 5 min after intravenous administration. However, uptake of Dex-g-PCL/SPIO nanocomposites in liver reticuloendothelial cells (Kupffer cells) did not immediately happen at shorter time points (<4 h) as verified by histology studies, and it was evident that more iron staining would be located in Kupffer cells 24 h after contrast agent administration. After 24 h and 10 d, the signal intensities (SI) gradually recovered, and SI changes were -44% and -31%, respectively. From our observation, the time window for enhanced-MRI could last at least 12 days and totally recovered after 16 days. This novel sensitive MRI contrast agent may find potential applications in discovering small liver lesions such as early tumor diagnosis. | WANG QiaoYing SU HongYing XIA ChunChao SUN JiaYu LIU Chen WANG ZhiYong GONG QiYong SONG Bin GAO FaBao AI Hua GU ZhongWei | 2009 | Chinese Science Bulletin2009，54，17： | 5 |
| 6 | The telomere-to-telomere genome of Fragaria vesca reveals the genomic evolution of Fragaria and the origin of cultivated octoploid strawberry显示文摘Fragaria vesca,commonly known as wild or woodland strawberry,is the most widely distributed diploid Fragaria species and is native to Europe and Asia.Because of its small plant size,low heterozygosity,and relative ease of genetic transformation,F.vesca has been a model plant for fruit research since the publication of its Illumina-based genome in 2011.However,its genomic contribution to octoploid cultivated strawberry remains a long-standing question.Here,we de novo assembled and annotated a telomere-to-telomere,gap-free genome of F.vesca‘Hawaii 4’,with all seven chromosomes assembled into single contigs,providing the highest completeness and assembly quality to date.The gap-free genome is 220785082 bp in length and encodes 36173 protein-coding gene models,including 1153 newly annotated genes.All 14 telomeres and seven centromeres were annotated within the seven chromosomes.Among the three previously recognized wild diploid strawberry ancestors,F.vesca,F.iinumae,and F.viridis,phylogenomic analysis showed that F.vesca and F.viridis are the ancestors of the cultivated octoploid strawberry F.×ananassa,and F.vesca is its closest relative.Three subgenomes of F.×ananassa belong to the F.vesca group,and one is sister to F.viridis.We anticipate that this high-quality,telomere-to-telomere,gap-free F.vesca genome,combined with our phylogenomic inference of the origin of cultivated strawberry,will provide insight into the genomic evolution of Fragaria and facilitate strawberry genetics and molecular breeding. | Yuhan Zhou Jinsong Xiong Ziqiang Shu Chao Dong Tingting Gu Pengchuan Sun Shuang He Mian Jiang Zhiqiang Xia Jiayu Xue Wasi Ullah Khan Fei Chen Zong-Ming Cheng | 2023 | Horticulture Research2023，10，4： | 4 |
| 7 | Control factors and porosity evolution of high-quality sandstone reservoirs of Kela-2 gas field in Kuqa Depression显示文摘By using the integrated methods includingsandbodies modelling of the outcrops, sedimentary facies ofthe cores and well logs of the drilled wells, and the reservoircorrelation of interwells, it is thought that the sandstone res-ervoirs of Kela-2 gas field are a suit of high-quality naturalgas reservoirs with great thickness, extensive and continuousdistribution, high porosity and permeability, and a few bar-rier beds. Sedimentary facies and microfacies are the mainfactors controlling the reservoir distribution and interiorheterogeneity. Based on a great deal of data of rock’s thinsections, porosity, permeability, and the parameters of capil-lary pressure, the reservoir diagenesis, controls, mechanismand evolution of pores have been studied. It is consideredthat compaction in the early stage and diagenetic dolomiteand calcite cements have effect on the decline of reservoirsproperty. Now compaction is chiefly middle to weak. Thebetter reservoirs have no or a few calcite cements. In theearly of deep buried stage, there are still mainly remainderprimary intergranular pores. The authigenic kaolinite ofreservoirs is the production of the dissolution of feldsparsand lithic fragments. The dissolution results in the partlymodified and broadened secondary intergranular pores. Inthe late of deep buried stage, structure fissures and over-pressure were in favor of improving and preservation ofthese pores. | Jinhua Jia Jiayu Gu | 2002 | Chinese Science Bulletin2002，47，S1： | 4 |
| 8 | Rule-and PSO Algorithm-based Dynamic Spatial Rescheduling Method for Hull Curved Block Construction显示文摘Due to no effective rescheduling method in hull curved block construction planning, existing scheduling planning can't be applied in practical production effectively. Two-dimensional layout and dynamic attributes of block construction planning are considered to develop a spatial rescheduling method, which is based on the spatial points searching rule and the particle swarm optimization(PSO) algorithm. A dynamic spatial rescheduling method is proposed to solve the manufacturing problem of rush-order blocks. Through spatial rescheduling, the rescheduling start time, the current processing information set and rescheduling blocks set can be obtained automatically. By using and updating the data of these sets, the rescheduling method combines the PSO algorithm with the spatial points searching rule to determine the rescheduling start time and layout of the blocks. Three types of dynamic events, including rush-order block delay, existing block delay and existing block position changes, are used to address problems with different function goals by setting different function weights. Finally, simulations based on three types of rush-order block events are performed to validate this method, including single rush-order block, multi rush-order blocks at the same time and multi rush-order blocks at different times. The simulation results demonstrate that this method can solve the rush-order block problems in hull block construction and reduce the interference to the existing manufacturing schedule. The proposed research provides a new rescheduling method and helps instruct scheduler to make production planning in hull block construction. | ZHANG Zhiying GU Jiayu XU Chen LI Zhen | 2013 | Chinese Journal of Mechanical Engineering2013，26，3： | 2 |
| 9 | Development of a CLDN18.2-targeting immuno-PET probe for non-invasive imaging in gastrointestinal tumors显示文摘Claudin18.2(CLDN18.2)is a tight junction protein that is overexpressed in a variety of solid tumors such as gastrointestinal cancer and oesophageal cancer.It has been identified as a promising target and a potential biomarker to diagnose tumor,evaluate efficacy,and determine patient prognosis.TST001 is a recombinant humanized CLDN18.2 antibody that selectively binds to the extracellular loop of human Claudin18.2.In this study,we constructed a solid target radionuclide zirconium-^(89)(^(89)Zr)labled-TST001 to detect the expression of in the human stomach cancer BGC823CLDN18.2 cell lines.The[^(89)Zr]Zr-desferrioxamine(DFO)-TST001 showed high radiochemical purity(RCP,>99%)and specific activity(24.15±1.34 GBq/mmol),and was stable in 5%human serum albumin,and phosphate buffer saline(>85%RCP at 96 h).The EC_(50) values of TST001 and DFO-TST001 were as high as 0.413±0.055 and 0.361±0.058 nM(P>0.05),respectively.The radiotracer had a significantly higher average standard uptake values in CLDN18.2-positive tumors than in CLDN18.2-negative tumors(1.11±0.02 vs.0.49±0.03,P=0.0016)2 days post injection(p.i.).BGC823CLDN18.2 mice models showed high tumor/muscle ratios 96 h p.i.with[^(89)Zr]Zr-DFO-TST001 was much higher than those of the other imaging groups.Immunohistochemistry results showed that BGC823CLDN18.2 tumors were highly positive(+++)for CLDN18.2,while those in the BGC823 group did not express CLDN18.2().The results of ex vivo biodistribution studies showed that there was a higher distribution in the BGC823CLDN18.2 tumor bearing mice(2.05±0.16%ID/g)than BGC823 mice(0.69±0.02%ID/g)and blocking group(0.72±0.02%ID/g).A dosimetry estimation study showed that the effective dose of[^(89)Zr]Zr-DFO-TST001 was 0.0705 mSv/MBq,which is within the range of acceptable doses for nuclear medicine research.Taken together,these results suggest that Good Manufacturing Practices produced by this immuno-positron emission tomography probe can detect CLDN18.2-overexpressing tumors. | Yan Chen Xingguo Hou Dapeng Li Jin Ding Jiayue Liu Zilei Wang Fei Teng Hongjun Li Fan Zhang Yi Gu Steven Yu Xueming Qian Zhi Yang Hua Zhu | 2023 | Journal of Pharmaceutical Analysis2023，13，4： | 2 |
| 10 | Accurate annotation of accessible chromatin in mouse and human primordial germ cells显示文摘广泛、精确的染色质改变在初发的细菌房间(PGC ) 期间是必要的为越过代的基因信息的永存的开发。这里,我们报导 DNase 我过分敏感的地点(DHS ) 标记的远侧的 cis 规章的元素(CRE ) 在鼠标和人的 PGC 开发期间显示出时间地限制的活动。把 DHS 地图用作代理,我们精确地在老鼠 PGC 定位 pluripotency 抄写因素的染色体宽的有约束力的地点。出人意料地,我们发现老鼠女性 meiotic 再结合热点能被 DHS 捕获,并且第一次,我们在老鼠女性 PGC 识别了 12,211 个再结合热点。与 meiotic 女性 PGC 的相对照,有丝分裂拘捕的男 PGC 的染色质 ? 通过在远侧的规章的区域的原子抄写因素 Y (NFY ) 绑定是容许的。而且,我们在 PGC CRE 上检验了进化压力,并且比较 genomic 分析表明那只老鼠和人的 PGC CRE evolutionarily 在哺乳动物外面越过脊椎动物树被保存并且出现强壮的保存。因此,我们的结果在鼠标和人的 PGC 开发期间揭示唯一的、时间地可存取的染色质配置。 | Jingyi Li Shijun Shen Jiayu Chen Wenqiang Liu Xiaocui Li Qianshu Zhu Beiying Wang Xiaolong Chen Li Wu Mingzhu Wang Liang Gu Hong Wang Jiqing Yin Cizhong Jiang Shaorong Gao | 2018 | Cell Research2018，28，11： | 2 |
| 11 | Ethnobotanical study on medicinal plants from the Dragon Boat Festival herbal markets of Qianxinan, southwestern Guizhou, China显示文摘Dragon Boat Festival herbal markets in the Qianxinan Buyi and Miao Autonomous Prefecture of southwestern Guizhou have a long well-conserved history.These markets,which are a feature of Buyi and Miao traditional medicines,contain a rich diversity of medicinal plants and traditional medical knowledge.Today,people in southwestern Guizhou still believe that using herbs during the Dragon Boat Festival prevents and can treat disease.In this study,we identified the fresh herbal plants sold at the herbal markets of Xingren City and Zhenfeng County in Qianxinan Buyi and Miao Autonomous Prefecture and quantified their importance.We identified 141 plant species(belonging to 114 genera and 61 families).The plant family with the most species was Asteraceae(14 species).Informants reported that most medicinal plants are herbaceous,with 95.7%of plants used for decoction and 30.5%used for medicinal baths.Medicinal plants are most commonly used to treat rheumatism,injury,and abdominal diseases.The utilization frequency index and relative importance values indicated that Artemisia argyi and Acorus calamus are the most important plants sold at herbal markets during the Dragon Boat Festival.The price of medicinal materials sold in the market may serve as an indicator of the conservation status of species in the region.These findings indicate that the Dragon Boat Festival herbal markets in the Qianxinan Buyi and Miao Autonomous Prefecture fully embodies the characteristics of indigenous ethnomedicine and culture,and also exhibits the diversity of plant resources.We recommend that rare and endangered plants in this region be domesticated and protected. | Wei Gu Xiaojiang Hao Zehuan Wang Jiayu Zhang Liejun Huang Shengji Pei | 2020 | Plant Diversity2020，42，6： | 1 |
| 12 | Flight Safety System Evaluation and Optimal Linear Prediction显示文摘The complexity of flight safety system is usually affected by a variety of uncertainties.The uncertainty of overall security situation of flight safety system are hardly determined.In this work,flight safety assessment index system is firstly established based on software hardware environment liveware management(SHELM)model.And flight safety assessment is also carried out with matter-element theory algorithm to obtain safety state.According to correlation degree values of each evaluation index,key indexes affected flight safety are obtained.Under the assumption that the flight safety system is a linear dynamic system and combining the above evaluation analysis,Kalman filter algorithm is used to carry out prediction analysis on security situation.A simulation analysis is carried out based on an actual flight safety situation of an airline.The results show that the security state of airline flight safety system in a short period of time can be obtained,and main factors affecting flight safety are found out.This provides a viable way for airlines to further strengthen flight safety management. | DING Songbin GU Qianqian LIU Jiayu | 2019 | Transactions of Nanjing University of Aeronautics and Astronautics2019，36，2： | 1 |
| 13 | Feature local binary patterns with application to eye detection显示文摘 | Gu Jiayu Liu Chengjun | 2013 | Neurocomputing2013，113，3： | 1 |
| 14 | Manganese ferrite nanoparticle micellar nanocomposites as MRI contrast agent for liver imaging显示文摘 | Jian Lu Shuli Ma Jiayu Sun Chunchao Xia Chen Liu Zhiyong Wang Xuna Zhao Fabao Gao Qiyong Gong Bin Song Xintao Shuai Hua Ai Zhongwei Gu | 2009 | Biomaterials2009，，15： | 1 |
| 15 | The genetic control of glabrous glume during African rice domestication显示文摘African cultivated rice,Oryza glaberrima,is characterized by its glabrous glumes.During domestication,the pubescent glumes of its wild ancestor,Oryza barthii,lost their trichomes,and in this study,we show that glabrous glume 5(GLAG5),a WUSCHEL-like homeobox transcription factor gene on chromosome 5,is required for trichome development.DNA methylation associated with an hATtransposable element inserted in the promoter region of GLAG5 is found to reduce its expression,leading to the formation of glabrous glumes and leaves in African cultivated rice.Among 82 African cultivated rice varieties investigated in this study,59(approximately 71%)lines exhibit glabrous glumes and harbor the hAT transposon;however,the other 23 varieties(approximately 29%),which exhibit pubescent glumes,lack the hAT transposon,indicating that glag5 had undergone strong artificial selection.Theπ;/π;ratios also show the hAT transposon insertions influence the genetic diversity of an approximately 150-kb interval encompassing the GLAG5 locus.The identification of the GLAG5 gene provides new insights into the domestication of cultivated rice in Africa.We speculate that the selection of varieties with mutations in their promoter regions is an important aspect of crop domestication. | Leqin Chang Min Hu Jing Ning Wei He Jiayu Gao Marie-Noelle Ndjiondjop Yongcai Fu Fengxia Liu Hongying Sun Ping Gu Chuanqing Sun Zuofeng Zhu | 2022 | Journal of Genetics and Genomics2022，49，5： | 1 |
| 16 | The features of reservoir and the formation of the high porosity and high permeability reservoir in Tarim basin显示文摘 | GU Jiayu JIA Jinhua FANG Hui | 2002 | Chinese Science Bulletin2002，，： | 1 |
| 17 | cAMP-PGC1α途径诱导的抗Warburg效应驱动胶质母细胞瘤细胞分化为星形胶质细胞显示文摘文章简介多形性胶质母细胞瘤(GBM)是人类最具侵袭性的肿瘤之一。虽然分化治疗已被提出作为治疗GBM的潜在方法,但诱导分化的机制仍然很不清楚。在此,课题组利用c AMP激活剂建立了GBM诱导分化模型,该模型特异性地指导GBM分化为星形胶质细胞。 | Fan Xing Yizhao Luan Jing Cai Sihan Wu Jialuo Mai Jiayu Gu Haipeng Zhang Kai Li Yuan Lin Xiao Xiao Jiankai Liang Yuan Li Wenli Chen Yaqian Tan Longxiang Sheng Bingzheng Lu Wanjun Lu Mingshi Gao Pengxin Qiu Xingwen Su Wei Yin Jun Hu Zhongping Chen Ke Sai Jing Wang Furong Chen Yinsheng Chen Shida Zhu Dongbing Liu Shiyuan Cheng 谢志 朱文博 颜光美 | 2018 | 科学新闻2018，0，4： | 1 |
| 18 | Neuregulin-1/ErbB4 upregulates acetylcholine receptors via Akt/mTOR/p70S6K:a study in a rat model of obstetric brachial plexus palsy and in vitro显示文摘In obstetric brachial plexus palsy(OBPP),the operative time window for nerve reconstruction of the intrinsic muscles of the hand(IMH)is much shorter than that of biceps.The reason is that the atrophy of IMH becomes irreversible more quickly than that of biceps.A previous study confirmed that the motor endplates of denervated intrinsic muscles of the forepaw(IMF)were destabilized,while those of denervated biceps remained intact.However,the specific molecular mechanism of regulating the self-repair of motor endplates is still unknown.In this study,we use a rat model of OBPP with right C5-C6 rupture plus C7-C8-T1 avulsion and left side as a control.Bilateral IMF and biceps are harvested at 5 weeks postinjury to assess relative protein and mRNA expression.We also use L6 skeletal myoblasts to verify the effects of signaling pathways regulating acetylcholine receptor(AChR)protein synthesis in vitro.The results show that in the OBPP rat model,the protein and mRNA expression levels of NRG-1/ErbB4 and phosphorylation of Akt/mTOR/p70S6K are lower in denervated IMF than in denervated biceps.In L6 myoblasts stimulated with NRG-1,overexpression and knockdown of ErbB4 lead to upregulation and downregulation of AChR subunit protein synthesis and Akt/mTOR/p70S6K phosphorylation,respectively.Inhibition of mTOR abolishes protein synthesis of AChR subunits elevated by NRG-1/ErbB4.Our findings suggest that in the OBPP rat model,lower expression of AChR subunits in the motor endplates of denervated IMF is associated with downregulation of NRG-1/ErbB4 and phosphorylation of Akt/mTOR/p70S6K.NRG-1/ErbB4 can promote protein synthesis of the AChR subunits in L6 myoblasts via phosphorylation of Akt/mTOR/p70S6K. | Jing Qiao Jiayu Sun Liang Chen Bo Li Yudong Gu | 2022 | Acta Biochimica et Biophysica Sinica2022，54，11： | 0 |
| 19 | Effects of Combined Stress from Salt and Herbicide on Microbial Remediation of Soil Contaminated by n-Hexadecane and Phenanthrene显示文摘In this study,physicochemical,cluster,and high-throughput sequencing analyses were used to investigate the joint effects of salt and herbicide(glyphosate)stress factors on the microbial remediation of soil contaminated by n-hexadecane and phenanthrene.Based on the soil’s physical and chemical properties,differences in microbial quantity and enzyme activities were analyzed among the samples,and how that influenced distribution of soil community structure was focused upon.After 120 days of indoor simulated remediation,the cumulative degradation rate of n-hexadecane decreased by 94.92%(blank control),96.96%(low concentration salt and glyphosate stress group),65.07%(high concentration salt and glyphosate stress group),while that of phenanthrene decreased by 87.33%(blank control),86.25%(low concentration salt and glyphosate stress group),58.45%(high concentration salt and glyphosate stress group).The combined stress of salt and herbicides was capable of lowering the reduction efficiency of organic matter,total nitrogen,and total phosphorus,and also restricting the growth of microorganisms and enzyme activities.Cluster analysis results indicated that the non-stress group was similar to the low-concentration compound stress group during different remedial period,whereas both of those differed starkly from the high-concentration compound stress group.High-throughput sequencing revealed that the dominant soil bacteria phyla shifted from Firmicutes to Actinobacteria within 120 days of remediation. | Liu Bingkun Zuo Shuai Wang Ruirui Dong Kangning Zhang Xiuxia Li Ruyue Hao Boyu Li Jing Yin Linghao Bai Yuhao Song Jiayu Gu Yingying Sun Juan | 2022 | China Petroleum Processing & Petrochemical Technology2022，24，2： | 0 |
| 20 | TET1蛋白亚型转换调控DNA去甲基化和小鼠发育显示文摘文章简介DNA甲基化氧化酶TET蛋白在介导DNA去甲基化和调控个体发育中均起着非常重要的作用。但是,TET蛋白如何识别基因组中的催化位点仍然有待研究。本研究通过细致地观测转录组学数据,意外发现了TET蛋白家族成员TET1在小鼠不同发育时期中存在两个亚型。其中全长TET1亚型(TET1e)仅在小鼠早期胚胎、小鼠胚胎干细胞和原始生殖细胞中表达; | Wenhao Zhang Weikun Xia Qiujun Wang Aaron J Towers Jiayu Chen Rui Gao Yu Zhang Chia-an Yen Ah Young Lee Yuanyuan Li Chen Zhou Kaili Liu Jing Zhang Tian-Peng Gu Xiuqi Chen Zai Chang Danny Leung Shaorong Gao Yong-hui Jiang 颉伟 | 2017 | 科学新闻2017，19，4： | 0 |
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