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| 1 | Pm21 from Haynaldia villosa Encodes a CC-NBS- LRR Protein Conferring Powdery Mildew Resistance in Wheat显示文摘 | Liping Xing Ping Hu Jiaqian Liu Kamil Witek Shuang Zhou Jiefei Xu Weihao Zhou Li Gao Zhenpu Huang Ruiqi Zhang Xiue Wang Peidu Chen Haiyan Wang Jonathan D.G. Jones Miroslava Karafiatova Jan Vrana Jan Baros Jaroslav Dolezel Yuanchun Tian Yufeng Wu Aizhong Cao | 2018 | Molecular Plant2018，11，6： | 16 |
| 2 | Tenofovir disoproxil fumarate therapy in patients with chronic hepatitis B and advanced fibrosis or compensated cirrhosis显示文摘Background and aims:Tenofovir disoproxil fumarate(TDF)is the first-line therapy for chronic hepatitis B.This interim analysis presents the efficacy and safety data for TDF at Week 144 in patients with chronic hepatitis B and advanced fibrosis or compensated cirrhosis from China.Methods:Patients were assessed for incidence of newly diagnosed hepatocellular carcinoma(HCC)and disease progression,liver stiffness measurement(LSM),virological suppression(serum hepatitis B virus DNA<20 IU/mL),alanine aminotransferase normalization,hepatitis B e antigen(HBeAg)loss and seroconversion,histological liver fibrosis score,and safety at Week 144.Results:Overall,197 patients were enrolled.At Week 144,the incidence of newly diagnosed HCC was observed in 2.1%patients,and the incidence of disease progression was observed in 3.6%patients.The mean(standard deviation)change in LSM from baseline was5.1(5.85)kPa.Serum hepatitis B virus DNA<20 IU/mL was observed in 94.1%patients,alanine aminotransferase normalization in 33.5%patients,HBeAg loss in 35.6%patients,and HBeAg seroconversion in 14.4%patients.Among patients with stage F3 or F4 fibrosis at baseline by LSM,38.3%patients regressed to stage F0/1,and 22.0%of patients regressed to stage F2 at Week 144.Overall,67.7%patients experienced≥1 adverse events,13.8%patients experienced TDF-related adverse events,and 16.4%patients experienced serious(none were TDF-related).Conclusions:At Week 144 of TDF treatment,low incidence of HCC and disease progression were reported.Virological suppression was observed in 94.1%patients,which was associated with fibrosis regression.No new safety events were identified. | Huiying Rao Jia Shang Qing Xie Jianqi Lian Pujun Gao Junping Shi Xinyue Chen Jiefei Wang Min Xu Liaoyun Zhang Yingren Zhao QingMao Maorong Wang Wei Zhao Zong Zhang Jidong Jia Hong Tang Jiming Zhang Xin Zheng Chang Liu Lai Wei | 2022 | iLIVER2022，1，3： | 1 |
| 3 | Expression profiles and function of Toll-like receptors 2 and 4 in peripheral blood mononuclear cells of chronic hepatitis B patients显示文摘 | Zhiao Chen Yuming Cheng Yongfen Xu Jing Liao Xiaonan Zhang Yunwen Hu Qin Zhang Jiefei Wang Zhanqing Zhang Fang Shen Zhenghong Yuan | 2008 | Clinical Immunology2008，，3： | 1 |
| 4 | Measuring Zak phase in room-temperature atoms显示文摘Cold atoms provide a flexible platform for synthesizing and characterizing topological matter,where geometric phases play a central role.However,cold atoms are intrinsically prone to thermal noise,which can overwhelm the topological response and hamper promised applications.On the other hand,geometric phases also determine the energy spectra of particles subjected to a static force,based on the polarization relation between Wannier-Stark ladders and geometric Zak phases.By exploiting this relation,we develop a method to extract geometric phases from energy spectra of room-temperature superradiance lattices,which are momentum-space lattices of timed Dicke states.In such momentum-space lattices the thermal motion of atoms,instead of being a source of noise,provides effective forces which lead to spectroscopic signatures of the Zak phases.We measure Zak phases directly from the anti-crossings between Wannier-Stark ladders in the Doppler-broadened absorption spectra of superradiance lattices.Our approach paves the way of measuring topological invariants and developing their applications in room-temperature atoms. | Ruosong Mao Xingqi Xu Jiefei Wang Chenran Xu Gewei Qian Han Cai Shi-Yao Zhu Da-Wei Wang | 2022 | Light(Science & Applications)2022，11，10： | 0 |
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