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| 1 | Dormancy Breaking and Storage Behavior of Garcinia cowa Roxb. (Guttiferae) Seeds: Implications for Ecological Function and Germplasm Conservation显示文摘The dormancy breaking and storage behavior of Garcinia cowa Roxb. seeds were investigated.The seeds of G. cowa had 8-11 months dormancy in their natural habitat. Seeds were matured and dispersed at the end of the rainy season (mid-late August to late September) and were scatter-hoarded by rodents as food for winter after the seeds had fallen to the ground. Seedlings often emerged in the forest during the rainy season (May to August) the following year. Intact seeds of G. cowa failed to germinate after being sown at 30 ℃ for 120 d and the mean germination time (MGT) of seeds cultured in a shade (50% sunlight)nursery was 252 d. The most effective method of breaking dormancy was to remove the seed coat totally,which reduced the MGT to 13 d at 30 ℃. Germination was also promoted by partial removal of the seed coat (excising the hilum and exposing the radicle) and chemical scarification (immersion in 1% H2O2 for 1 d).Unscarified seeds take up water rapidly in the first 96 h, but water was absorbed by the outside seed coat,without penetrating through it. The moisture content (MC) of G. cowa seeds was high (50% in fresh weight)at shedding. The seeds could tolerate desiccation to some extent, until the MC reached approximately 40%;below that, the viability decreases rapidly and all seeds died at approximately 17% of MC. Seed viability decreased rapidly when seeds were chilled at 4 ℃; germination was 2% after storage for 1 week. Even stored at 10 ℃, seeds began to be damaged after 4 weeks. Seed storage for 1 yr revealed that in both dry (relative humidity (35 ± 5)%) and moist (wet sand) storage conditions, seed viability declined, but germination percentages for seeds stored under moist conditions are better than for seed stored under dry conditions.Because of their low tolerance to desiccation, marked chilling sensitivity and relatively short lifespan, G.cowa seeds should be classified into the tropical recalcitrant category. The ecological implications of dormant recalcitrant seeds and cues on storing recalcitrant seeds were discussed. | YongLIU Yu-PingQ1U LingZHANG JinCHEN | 2005 | Journal of Integrative Plant Biology2005，47，1： | 22 |
| 2 | Comparison of lymph node number and prognosis in gastric cancer patients with perigastric lymph nodes retrieved by surgeons and pathologists显示文摘Objective: To compare the numbers of positive and total lymph nodes and prognosis in gastric cancer patients whose perigastric lymph node retrieval was performed by surgeons and pathologists.Methods: We conducted a retrospective analysis of clinical and follow-up data from 1,056 patients who underwent gastric cancer D2 radical lymph node resection between January 2008 and December 2010 in the Gastrointestinal Surgery Department of Yantai Yuhuangding Hospital.The follow-up ended in December 2015.Patients were divided into two groups according to the specialty of physicians who performed the postoperative perigastric lymph node retrieval: the surgeon group(475 cases) and the pathologist group(581 cases).The numbers of positive and total perigastric lymph nodes and the 3- and 5-year survival were compared between gastric cancer patients in the two groups overall and stratified by TNM stage(AJCC 7th Edition).Results: Overall, the numbers of positive and total lymph nodes were significantly higher in the surgeon group than in the pathologist group(6.53±4.07 vs.4.09±3.70, P=0.021; 29.64±11.50 vs.20.71±8.56, P<0.001).Further analysis showed that the total number of lymph nodes in stage Ⅰ patients(19.40±9.62 vs.15.45±8.59, P=0.011) and the numbers of positive and total lymph nodes in stage Ⅱ(1.38±1.08 vs.0.87±1.55, P=0.031; 25.35±10.80 vs.16.75±8.56, P<0.001) and stage Ⅲ patients(8.11±6.91 vs.6.66±5.12, P=0.026; 32.34±12.55 vs.25.45±8.31, P<0.001)were significantly higher in the surgeon group than in the pathologist group.The survival analysis showed that the3- and 5-year survival of stage Ⅱ and Ⅲ patients was significantly higher in the surgeon group than in the pathologist group(82.0% vs.73.1%, 69.5% vs.61.2%, P=0.038; 49.2% vs.38.9%, 36.3% vs.28.0%; P=0.045).Conclusions: Compared with retrieval performed by pathologists, postoperative perigastric lymph node retrieval performed by surgeons was associated with significant increase in the total lymph node number of stage Ⅰ patients, the numbers of positive and total lymph nodes of stage Ⅱ and Ⅲ patients, and the survival of stage Ⅱ and stage Ⅲ gastric cancer patients. | Lixin Jiang Zengwu Yao Yifei Zhang Jinchen Hu Dawei Zhao Huiyuan Zhai Xixun Wang Zhenbin Zhang Dong Wang | 2016 | Chinese Journal of Cancer Research2016，28，5： | 5 |
| 3 | 基于改进全息希尔伯特谱分析的旋转机械故障诊断方法显示文摘时频分析方法能够有效同时提取故障设备振动信号的时间和频率信息,但在全面反映非线性振动信号幅值调制与频率调制特征之间的跨尺度耦合关系方面仍存在局限,且容易受到噪声干扰。对此,创新性地将全息希尔伯特谱分析(Holo-Hilbert spectral analysis,HHSA)方法引入到机械故障诊断中。HHSA通过双层经验模态分解(EMD)结构可完整地描述振动信号的内部调制特性,非常适合机械局部故障的检测。同时,为了进一步提升HHSA的诊断精度、抑制EMD模态混叠和噪声干扰,提出一种基于改进再生相移正弦辅助经验模式分解(Improved regenerated phase-shifted sinusoid-assisted EMD,IRPSEMD)的改进HHSA方法(IHHSA)。通过仿真信号验证IHHSA方法用于局部故障检测和诊断的有效性。最后,将IHHSA应用于齿轮裂纹故障和滚动轴承局部故障诊断中,结果表明,提出的IHHSA方法能够更全面地反映和呈现非线性故障振动信号的内部调制关系,且具有更好的故障识别能力。 | 郑近德 应万明 潘海洋 童靳于 刘庆运 JI Jinchen | 2023 | 机械工程学报2023，59，1： | 4 |
| 4 | Searching for the Nano-Hertz Stochastic Gravitational Wave Background with the Chinese Pulsar Timing Array Data ReleaseⅠ显示文摘Observing and timing a group of millisecond pulsars with high rotational stability enables the direct detection of gravitational waves(GWs).The GW signals can be identified from the spatial correlations encoded in the times-of-arrival of widely spaced pulsar-pairs.The Chinese Pulsar Timing Array(CPTA)is a collaboration aiming at the direct GW detection with observations carried out using Chinese radio telescopes.This short article serves as a“table of contents”for a forthcoming series of papers related to the CPTA Data Release 1(CPTA DR1)which uses observations from the Five-hundred-meter Aperture Spherical radio Telescope.Here,after summarizing the time span and accuracy of CPTA DR1,we report the key results of our statistical inference finding a correlated signal with amplitude logA_(c)=-14.4_(-2.8)^(+1.0)for spectral index in the range ofα∈[-1.8,1.5]assuming a GW background(GWB)induced quadrupolar correlation.The search for the Hellings–Downs(HD)correlation curve is also presented,where some evidence for the HD correlation has been found that a 4.6σstatistical significance is achieved using the discrete frequency method around the frequency of 14 n Hz.We expect that the future International Pulsar Timing Array data analysis and the next CPTA data release will be more sensitive to the n Hz GWB,which could verify the current results. | Heng Xu Siyuan Chen Yanjun Guo Jinchen Jiang Bojun Wang Jiangwei Xu Zihan Xue RNicolas Caballero Jianping Yuan Yonghua Xu Jingbo Wang Longfei Hao Jingtao Luo Kejia Lee Jinlin Han Peng Jiang Zhiqiang Shen Min Wang Na Wang Renxin Xu Xiangping Wu Richard Manchester Lei Qian Xin Guan Menglin Huang Chun Sun Yan Zhu | 2023 | Research in Astronomy and Astrophysics2023，23，7： | 3 |
| 5 | Genomic landscapes of Chinese sporadic autism spectrum disordersrevealed by whole-genome sequencing显示文摘Autism spectrum disorder (ASD) is a neurodevelopmental disorder with considerable clinical and genetic heterogeneity.In this study,we identified all classes of genomic variants from whole-genome sequencing (WGS) dataset of 32 Chinese trios with ASD,including de novo mutations,inherited variants,copy number variants (CNVs) and genomic structural variants.A higher mutation rate (Poisson test,P<2.2×10^(-16)) in exonic (1.37×10^(-8)) and 3'-UTR regions (1.42×10^(-8)) was revealed in comparison with that of whole genome (1.05×10^(-8)).Using an integrated model,we identified 87 potentially risk genes (P<0.01) from 4832 genes harboring various rare deleterious variants,including CHD8 and NRXN2,implying that the disorders may be in favor to multiple-hit.In particular,frequent rare inherited mutations of several microcephaly-associated genes (ASPM,WDR62,and ZNF335)were found in ASD.In chromosomal structure analyses,we found four de novo CNVs and one de novo chromosomal rearrangement event,including a de novo duplication of UBE3A-containing region at 15q11.2-q13.1,which causes Angelman syndrome and microcephaly,and a disrupted TNR due to de novo chromosomal translocation t (1;5) (q25.1;q33.2).Taken together,our results suggest that abnormalities of centrosomal function and chromatin remodeling of the microcephaly-associated genes may be implicated in pathogenesis of ASD.Adoption of WGS as a new yet efficient technique to illustrate the full genetic spectrum in complex disorders,such as ASD,could provide novel insights into pathogenesis,diagnosis and treatment. | Jinyu Wu Ping Yu Xin Jin Xiu Xu Jinchen Li Zhongshan Li Mingbang Wang Tao Wang Xueli Wu Yi Jiang Wanshi Cai Junpu Mei Qingjie Min Qiong Xu Bingrui Zhou Hui Guo Ping Wang Wenhao Zhou Zhengmao Hu Yingrui Li Tao Cai Yi Wang Kun Xia Yong-Hui Jiang Zhong Sheng Sun | 2018 | Journal of Genetics and Genomics2018，45，10： | 3 |
| 6 | DASP: Defect and Dopant ab-initio Simulation Package显示文摘In order to perform automated calculations of defect and dopant properties in semiconductors and insulators, we developed a software package, the Defect and Dopant ab-initio Simulation Package(DASP), which is composed of four modules for calculating:(ⅰ) elemental chemical potentials,(ⅱ) defect(dopant) formation energies and charge-state transition levels,(ⅲ) defect and carrier densities and(ⅳ) carrier dynamics properties of high-density defects. DASP uses the materials genome database for quick determination of competing secondary phases when calculating the elemental chemical potential that stabilizes compound semiconductors. DASP calls the ab-initio software to perform the total energy, structural relaxation and electronic structure calculations of the defect supercells with different charge states, based on which the defect formation energies and charge-state transition levels are calculated. Then DASP can calculate the equilibrium densities of defects and electron and hole carriers as well as the Fermi level in semiconductors under different chemical potential conditions and growth/working temperature. For high-density defects, DASP can calculate the carrier dynamics properties such as the photoluminescence(PL) spectrum and carrier capture cross sections which can interpret the deep level transient spectroscopy(DLTS). Here we will show three application examples of DASP in studying the undoped GaN, C-doped GaN and quasi-one-dimensional SbSeI. | Menglin Huang Zhengneng Zheng Zhenxing Dai Xinjing Guo Shanshan Wang Lilai Jiang Jinchen Wei Shiyou Chen | 2022 | Journal of Semiconductors2022，43，4： | 3 |
| 7 | Synchronization of networked multibody systems using fundamental equation of mechanics显示文摘From the analytical dynamics point of view, this paper develops an optimal control framework to synchronize networked multibody systems using the fundamental equation of mechanics. A novel robust control law derived from the framework is then used to achieve complete synchronization of networked identical or non-identical multibody systems formulated with Lagrangian dynamics. A distinctive feature of the developed control strategy is the introduction of network structures into the control requirement.The control law consists of two components, the first describing the architecture of the network and the second denoting an active feedback control strategy. A corresponding stability analysis is performed by the algebraic graph theory. A representative network composed of ten identical or non-identical gyroscopes is used as an illustrative example.Numerical simulation of the systems with three kinds of network structures, including global coupling, nearest-neighbour, and small-world networks, is given to demonstrate effectiveness of the proposed control methodology. | Jun LIU Jinchen JI Jin ZHOU | 2016 | Applied Mathematics and Mechanics(English Edition)2016，37，5： | 2 |
| 8 | Solid Superacid Catalyzed Efficient Synthesis of 2-Diethylaminoethyl Aryloxyacetates显示文摘2-Diethylaminoethyl aryloxyacetates are prepared efficiently in 75~95% yields by condensation of the corresponding aryloxyacetic acids with 2-diethylaminoethanol in the presence of catalytic amount of solid superacid SO4 -/Fe2O3. | MingDeCHEN AnQiCHEN MinLIN ZhaoYingLI JinCHEN | 2005 | Chinese Chemical Letters2005，16，2： | 2 |
| 9 | Graphene-nickel nitride hybrids supporting palladium nanoparticles for enhanced ethanol electrooxidation显示文摘Electrocatalysts for ethanol oxidation reaction(EOR)are generally limited by their poor durability because of the catalyst poisoning induced by the reaction intermediate carbon monoxide(CO).Therefore,the rapid oxidation removal of CO intermediates is crucial to the durability of EOR-based catalysts.Herein,in order to effectively avoiding the catalyst CO poisoning and improve the durability,the graphene-nickel nitride hybrids(AG-Ni_(3)N)were designed for supporting palladium nanoparticles(Pd/AG-Ni_(3)N)and then used for ethanol electrooxidation.The density functional theory(DFT)calculations demonstrated the introduction of AG-Ni_(3)N depresses the CO absorption and simultaneously promotes the adsorption of OH species for CO oxidation removal.The fabricated Pd/AG-Ni_(3)N catalyst distinctively exhibits excellent electroactivity with the mass catalytic activity of 3499.5 m A mg^(-1) on EOR in alkaline media,which is around 5.24 times higher than Pd/C(commercial catalyst).Notably,the Pd/AG-Ni_(3)N hybrids display excellent stability and durability after chronoamperometric measurements with a total operation time of 150,000 s. | Tong Wu Xiao Wang Ahmet Emrehan Emre Jinchen Fan Yulin Min Qunjie Xu Shigang Sun | 2021 | Journal of Energy Chemistry2021，30，4： | 2 |
| 10 | Effects of elastic anisotropy in phononic band-gap plates with two-dimensional lattices 显示文摘 | HSU Jinchen | 2013 | Journal of Physics D: Applied Physics2013，46，01： | 1 |
| 11 | Preparation and char-acterization of sulfonated graphene- enhanced poly (vinyl alco-hol) composite hydrogel and its application as dye absorbent显示文摘 | Li Hong Fan Jinchen Shi Zixing | 2015 | Polymer2015，，60： | 1 |
| 12 | Experimental and theoretical studies of gas adsorption in Cu3 ( BTC ) 2 : An effective activation procedure 显示文摘 | Liu Jinchen Culp J T Natesakhawat S | 2007 | J Phys Chem C2007，111，26： | 1 |
| 13 | Fuzzy Adaptive Kal- man Filter for Marine INS/GPS Navigation显示文摘 | Zhilan Xiong Yanliug Hao Jinchen Wei | 2005 | IEEE Mechatronics and Automation2005，2，29： | 1 |
| 14 | Novel discovery of schisandrin A regulating the interplay of autophagy and apoptosis in oligoasthenospermia by targeting SCF/c-kit and TRPV1 via biosensors显示文摘Oligoasthenospermia is the primary cause of infertility.However,there are still enormous challenges in the screening of critical candidates and targets of oligoasthenospermia owing to its complex mechanism.In this study,stem cell factor(SCF),c-kit,and transient receptor potential vanilloid 1(TRPV1)biosensors were successfully established and applied to studying apoptosis and autophagy mechanisms.Interestingly,the detection limit reached 2.787×10^(-15)g/L,and the quantitative limit reached 1.0×10^(-13)g/L.Furthermore,biosensors were used to investigate the interplay between autophagy and apoptosis.Schisandrin A is an excellent candidate to form a system with c-kit similar to SCF/c-kit with a detection constant(K_(D))of 5.701×10^(-11)mol/L,whereas it had no affinity for SCF.In addition,it also inhibited autophagy in oligoasthenospermia through antagonizing TRPV1 with a K_(D) of up to 4.181×10^(-10)mol/L.In addition,in vivo and in vitro experiments were highly consistent with the biosensor.In summary,high-potency schisandrin A and two potential targets were identified,through which schisandrin A could reverse the apoptosis caused by excessive autophagy during oligoasthenospermia.Our study provides promising insights into the discovery of effective compounds and potential targets via a well-established in vitro-in vivo strategy. | Lijuan Ma Boyi Li Jinchen Ma Chunyuan Wu Nan Li Kailin Zhou Yun Yan Mingshuang Li Xiaoyan Hu Hao Yan Qi Wang Yanfei Zheng Zhisheng Wu | 2023 | Acta Pharmaceutica Sinica B2023，13，6： | 1 |
| 15 | Microstructure Characteristics of Ni-Nb Near Eutectic Alloy during EBFZM Directional Solidification显示文摘Microstructure Characteristic of Ni-Nb near eutectic alloy is systematically investigated during directional solidification with electron beam floating zone melting (EBFZM). The effect of the Zone melting rate on the microstructure has also been studied. | Jinjiang YU Jun ZHANG and Hengzhi FU State Key Laboratory of Solidification Processing, Northwestern Polytechnical University, Xi’an 710072, China Jinchen ZHAO General Research institute for iron & Steel, Beijing 100081, China | 2001 | Journal of Materials Science & Technology2001，17，1： | 1 |
| 16 | Positive effects of treatment of donor cells with aphidicolin on the preimplantation development of somatic cell nuclear transfer embryos in Chinese Bama mini‐pig (Sus Scrofa)显示文摘 | Ting‐YuZHANG Jian‐JunDAI Cai‐FengWU Xiao‐LongGU LiangLIU Zhi‐QiangWU Yi‐ NiXIE BinWU Hui‐LanCHEN YaoLI Xue‐JinCHEN De‐FuZHANG | 2012 | Animal Science Journal2012，，2： | 1 |
| 17 | Mapping of de novo mutations in primary biliary cholangitis to a disease-specific co-expression network underlying homeostasis and metabolism显示文摘Primary biliary cholangitis(PBC) is an autoimmune disease involving dysregulation of a broad array of homeostatic and metabolic processes. Although considerable single-nucleotide polymorphisms have been unveiled, a large fraction of risk factors remains enigmatic. Candidate genes with rare mutations that tend to confer more deleterious effects need to be identified. To help pinpoint cellular and developmental mechanisms beyond common noncoding variants, we integrate whole exome sequencing with integrative network analysis to investigate genes harboring de novo mutations. Prominent convergence has been revealed on a network of disease-specific co-expression comprised of 55 genes associated with homeostasis and metabolism. The transcription factor gene MEF2 D and the DNA repair gene PARP2 are highlighted as hub genes and identified to be up-and down-regulated, respectively, in peripheral blood data set. Enrichment analysis demonstrates that altered expression of MEF2 D and PARP2 may trigger a series of molecular and cellular processes with pivotal roles in PBC pathophysiology. Our study identifies genes with de novo mutations in PBC and suggests that a subset of genes in homeostasis and metabolism tend to act in synergy through converging on co-expression network, providing novel insights into the etiology of PBC and expanding the pool of molecular candidates for discovering clinically actionable biomarkers. | Lu Wang Jinchen Li Chan Wang Ruqi Tang Jialong Liang Yuhua Gong Yaping Dai Ningling Ding Jian Wu Na Dai Lei Liu Yi Zhao Youlin Shao Weifeng Zhao Peng Jiang Xingjuan Shi Weichang Chen Ye Tian Xiangdong Liu Xiong Ma Zhongsheng Sun | 2022 | Journal of Genetics and Genomics2022，49，2： | 1 |
| 18 | Research on the Seismotectonic Setting in Beibu Gulf Waters显示文摘In this paper we discuss the seismogenic structures of the two earthquakes occurring in the Beibu Gulf waters,based on the investigation of geological structure,faults,geophysical fields,seismicity and earthquake focal mechanism.The results show that the NEE trending faults along the boundary of the Wushi depression are the dominating seismogenic structures,and the NW trending faults are the key factors of stress concentration.The results also show that high seismicity has a significant relationship with the late Cenozoic deposition center in the Beibu Gulf,and their NE-NEE trending boundary faults are important to the identification of seismogenic structures.The special arcuate fault segment or the intersection point of the NW trending faults and NE-NEE trending boundary faults is a possible location of future earthquakes. | Li Jinchen Pan Hua Chen Wenbin | 2010 | Earthquake Research in China2010，24，2： | 1 |
| 19 | Enhancement of ductility of existing seismic steel m-oment connections 显示文摘 | Sheng Jinchen TSAO Y C CHA0 Y C | 2001 | Joumal of Structural Engineering2001，127，5： | 1 |
| 20 | Atomically detailed models of gas mixture diffusion through CuBTC membranes 显示文摘 | Keskin S Liu Jinchen Johnson J K | 2009 | Micropor Mesopor Mater2009，125，： | 1 |
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