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| 1 | Diterpenoid UDP-Glycosyltransferases from Chinese Sweet Tea and Ashitaba Complete the Biosynthesis of Rubusoside显示文摘 | Yuwei Sun Zhuo Chen Jianxu Li Jianhua Li Huajun LV Jingya Yang Weiwei Li Dingan Xie Zhiqiang Xiong Peng Zhang Yong Wang | 2018 | Molecular Plant2018，11，10： | 7 |
| 2 | Chromopeptide A, a highly cytotoxic depsipeptide from the marine sediment-derived bacterium Chromobacterium sp. HS-13-94显示文摘A bicyclic depsipeptide, chromopeptide A(1), was isolated from a deep-sea-derived bacterium Chromobacterium sp. HS-13-94. Its structure was determined by extensive spectroscopic analysis and by comparison with a related known compound. The absolute configuration of chromopeptide A was established by X-ray diffraction analysis employing graphite monochromated Mo K_α radiation(λ ? 0.71073 ?) with small Flack parameter 0.03. Chromopeptide A suppressed the proliferation of HL-60, K-562, and Ramos cells with average IC_(50) values of 7.7, 7.0, and 16.5 nmol/L, respectively. | Zhenfang Zhou Xin Wang Hui Zhang Jingya Sun Linghui Zheng Hongchun Liu Jidong Wang Aijun Shen Meiyu Geng Yuewei Guo | 2015 | Acta Pharmaceutica Sinica B2015，5，1： | 6 |
| 3 | Enhancing the expansion of a plasma shockwave by crater-induced laser refocusing in femtosecond laser ablation of fused silica显示文摘The dynamics of plasma and shockwave expansion during two femtosecond laser pulse ablation of fused silica are studied using a time-resolved shadowgraph imaging technique. The experimental results reveal that during the second pulse irradiation on the crater induced by the first pulse, the expansion of the plasma and shockwave is enhanced in the longitudinal direction. The plasma model and Fresnel diffraction theory are combined to calculate the laser intensity distribution by considering the change in surface morphology and transient material properties. The theoretical results show that after the free electron density induced by the rising edge of the pulse reaches the critical density, the originally transparent surface is transformed into a transient high-reflectivity surface(metallic state). Thus, the crater with a concave-lens-like morphology can tremendously reflect and refocus the latter part of the laser pulse, leading to a strong laser field with an intensity even higher than the incident intensity. This strong refocused laser pulse results in a stronger laser-induced air breakdown and enhances the subsequent expansion of the plasma and shockwave. In addition, similar shadowgraphs are also recorded in the single-pulse ablation of a concave microlens, providing experimental evidence for the enhancement mechanism. | QINGSONG WANG LAN JIANG JINGYA SUN CHANGJI PAN WEINA HAN GUOYAN WANG HAO ZHANG COSTAS P.GRIGOROPOULOS YONGFENG LU | 2017 | Photonics Research2017，5，5： | 5 |
| 4 | Ultrafast optical response and ablation mechanisms of molybdenum disulfide under intense femtosecond laser irradiation显示文摘Numerous valuable studies on electron dynamics have focussed on the extraordinary properties of molybdenum disulfide(MoS_(2));however,most of them were confined to the level below the damage threshold.Here the electron dynamics of MoS_(2) under intense ultrafast laser irradiation was investigated by experiments and simulations.Two kinds of ablation mechanisms were revealed,which led to two distinct types of electron dynamics and final ablation morphology.At a higher fluence,the emergence of superheated liquid induced a dramatic change in the transient reflectivity and micro-honeycomb structures.At a lower fluence,the material was just removed by sublimation,and the ablation structure was relatively flat.X-ray photoelectron spectroscopic(XPS)measurements demonstrated that thermal decomposition only occurred at the higher fluence.Furthermore,a theoretical model was developed to deeply reveal the ultrafast dynamics of MoS_(2) ablation.The simulation results were in good agreement with the temporal and spatial reflectivity distribution obtained from the experiment.The electron and lattice temperature evolution was also obtained to prove the ablation mechanism.Our results revealed ultrafast dynamics of MoS_(2) above the damage threshold and are helpful for understanding the interaction mechanism between MoS_(2) and intense ultrafast lasers,as well as for MoS_(2) processing applications. | Changji Pan Lan Jiang Jingya Sun Qingsong Wang Feifei Wang Kai Wang Yongfeng Lu Yeliang Wang Liangti Qu Tianhong Cui | 2020 | Light(Science & Applications)2020，9，1： | 4 |
| 5 | Berry syndrome: a rare cardiac malformation with extra-cardiac findings显示文摘Dear Editor,Berry syndrome is a rare combination of congenital cardiac malformations characterized by four abnormal features;namely,an aortopulmonary window(APW),aortic origin of the right pulmonary artery,hypoplasia or interruption of the aortic arch,with an intact ventricular septum.The disease was first reported by Berry in 1982,who estimated the incidence within the population with congenital cardiac malformations to be 0.046%(Berry et al.,1982).Until recently, | Jingya Li Ya Yang Xiaomin Duan Lanzhong Jin Lin Zheng Xin Zhang Haiyan Wei Yan Sun Xiaolin Zhang Pei Li Jiao Yang Ning Ma Fangyun Wang | 2017 | Science China(Life Sciences)2017，60，7： | 3 |
| 6 | Ultrafast dynamics observation during femtosecond laser-material interaction显示文摘Femtosecond laser technology has attracted significant attention from the viewpoints of fundamental and application;especially femtosecond laser processing materials present the unique mechanism of laser-material interaction.Under the extreme nonequilibrium conditions imposed by femtosecond laser irradiation,many fundamental questions concerning the physical origin of the material removal process remain unanswered.In this review,cutting-edge ultrafast dynamic observation techniques for investigating the fundamental questions,including timeresolved pump-probe shadowgraphy,ultrafast continuous optical imaging,and four-dimensional ultrafast scanning electron microscopy,are comprehensively surveyed.Each technique is described in depth,beginning with its basic principle,followed by a description of its representative applications in laser-material interaction and its strengths and limitations.The consideration of temporal and spatial resolutions and panoramic measurement at different scales are two major challenges.Hence,the prospects for technical advancement in this field are discussed finally. | Baoshan Guo Jingya Sun YongFeng Lu Lan Jiang | 2019 | International Journal of Extreme Manufacturing2019，1，3： | 2 |
| 7 | Enhanced catalysis of ultrasmall Au-MoS_2 clusters against reactive oxygen species for radiation protection显示文摘Ionizing radiation produces excessive reactive oxygen species(ROS) which impose detrimental effects on biological systems. Thus, it is important to explore clinically safe and efficacious radioprotection agents to scavenge ROS and reduce the risks of radiotherapy. Recently, emerging catalytic nanomaterials such as sulfide nanomaterials have shown capability of clearing ROS in vivo by unique electron transfers between atoms, but their catalytic activities are yet suboptimal. As such, there is an unmet need to improve catalytic properties for stronger antioxidant activities and radiation protection. Herein, we prepared ultrasmall Au-MoS_2 clusters(~2.5 nm) and they showed enhanced catalytic properties via gold intercalation facilitating increased active sites and synergistic effects. Electrocatalysis results revealed that the catalytic activity of Au-MoS_2 towards H2O_2 was superior to ultrasmall MoS_2 without Au. As a result, we found that improving the electrocatalytic property of Au-MoS_2 can effectively enhance corresponding antioxidant activities and radioprotection effects in vivo. In addition, Au-MoS_2 also showed significant radioprotection in vitro and dramatically reduced the excess of radiation-induced adverse ROS. It also rescued radiation-induced DNA damages and protected the bone marrow hematopoietic system from ionizing radiation. | Peixian Bian Jinxuan Zhang Junying Wang Jiang Yang Jingya Wang Haile Liu Yuanming Sun Meixian Li Xiao-Dong Zhang | 2018 | Science Bulletin2018，63，14： | 2 |
| 8 | A Review of Co-processing of Kitchen Waste and Municipal Residual Sludge显示文摘In this paper,the methods of kitchen waste disposal in recent years were summed up,and the advantages and disadvantages of the current treatment methods were analyzed. At the same time,it has been found that the co-processing of kitchen waste and residual sludge not only has dealt with both kitchen waste and residual sludge,but also the carbon and nitrogen ratio and moisture content of the mixture are balanced,and increases the processing efficiency significantly. It has a certain processing advantage. At present,most research is about the anaerobic digestion of kitchen waste and residual sludge,and the process is more mature,but the study of VFAs accumulation is still insufficient. Aerobic composting is still in the early stage of development,and there are few studies on it at home and abroad. Meanwhile,prospects for the kitchen waste recycling were made in this article. | Han Houfeng Zhuang Pingfang Liu Mei Rong Zhenying Weng Yisong Chen Qingguo Sun Jingya | 2018 | Meteorological and Environmental Research2018，9，4： | 2 |
| 9 | Structure-Mediated Excitation of Air Plasma and Silicon Plasma Expansion in Femtosecond Laser Pulses Ablation显示文摘Femtosecond laser-induced surface structures upon multiple pulses irradiation are strongly correlated with the pulse number,which in turn signifcantly afects successive laser-material interactions.By recording the dynamics of femtosecond laser ablation of silicon using time-resolved shadowgraphy,here we present direct visualization of the excitation of air plasma induced by the refected laser during the second pulse irradiation.Te interaction of the air plasma and silicon plasma is found to enhance the shockwave expansion induced by silicon ablation in the longitudinal direction,showing anisotropic expansion dynamics in diferent directions.We further demonstrate the vanishing of air plasma as the pulse number increases because of the generation of a rough surface without light focusing ability.In the scenario,the interaction of air plasma and silicon plasma disappears;the expansion of the silicon plasma and shockwave restores its original characteristic that is dominated by the laser-material coupling.Te results show that the excitation of air plasma and the laser-material coupling involved in laser-induced plasma and shockwave expansion are structure mediated and dependent on the pulse number,which is of fundamental importance for deep insight into the nature of laser-material interactions during multiple pulses ablation. | Qingsong Wang Lan Jiang Jingya Sun Changji Pan Weina Han Guoyan Wang Feifei Wang Kaihu Zhang Ming Li Yongfeng Lu | 2018 | Research2018，，1： | 2 |
| 10 | DNA replication origins, ORC/DNA interaction, and assembly of pre-replication complex in eukaryotes显示文摘在真核细胞的房间的 Chromosomal DNA 复制高度复杂、复杂地调整。由于它的大尺寸,一个典型真核细胞的染色体包含地点把 DNA 合成发生的 DNA 复制起源称为的几千开始中的百~十个。因为仅仅 DNA 的某个数量能在一有限时间从单个起源被复制,多重开始地点移开一种染色体尺寸的限制。这些多重起源的激活必须被协调以便 chromosomal DNA 的每个片断精确每房间周期被复制仅仅一次。尽管 DNA 复制是为房间生长的一个重要过程,它的机制高度被保存,最近的研究也沿着进化的线在起源结构,复制前建筑群(pre-RC ) 的集会和复制开始的规定揭示重要差异。在分裂酵母 Schizosaccharomyces pombe 的 DNA 复制起源被发现包含由除必要起源识别以外的 Sap1 蛋白质是固定的第二个必要元素复杂绑定的地点。Sap1 最近被表明是在装载开始蛋白质 Cdc18 到起源起一个必要作用并且直接因此参予 pre-RC 形成的新奇复制开始蛋白质。在这评论,我们在理解 DNA 复制起源怎么被组织, pre-RC 怎么并且怎么被装配总结最近的进展 DNA 复制在酵母和 metazoans 被开始并且调整。 | Jingya Sun Daochun Kong | 2010 | Acta Biochimica et Biophysica Sinica2010，42，7： | 2 |
| 11 | Traditional Chinese Medicine guidelines for coronavirus disease 2019显示文摘OBJECTIVE:To summarize the evidence from Traditional Chinese Medicine(TCM)practice in the treatment of coronavirus disease 2019(COVID-19)and provide timely clinical practice guidance.METHODS:The guidelines were developed in accordance with the World Health Organization rapid guideline process.The evidence on TCM for COVID-19 from published guidelines,direct and indirect published clinical evidence,first hand clinical data,and expert experience and consensus were collected.The grading of recommendations assessment,development and evaluation(GRADE)method was used to grade the evidence and make the recommendations.RESULTS:Based on the available evidence,the guidelines recommended 17 Chinese medicines for COVID-19:2 Chinese herbal granules,7 Chinese patent medicines,and 8 Chinese herbal injections.CONCLUSION:As the literature search was conducted on March,any subsequent versions of these guidelines require an up-to-date literature review.We hope that the evidence summary in these guidelines will be helpful in global efforts to address COVID-19. | Liang Ning Ma Yanfang Wang Jingya Li Huizhen Wang Xiaohui Jiao Liwen Liu Bin Ma Yan Zhao Chen Luo Xufei Zhao Siya Lu Meng Cao Jin Hu Wenpin Zhang Hairong Liu Guoxiu Lu Cheng Liu Mengyu Li Li Han Xuejie Liu Yuqi Wang Liying Zhao Xueyao Wei Dongfeng Bai Jing Sun Mingyu Yang Yong Wu Xiaodan Chen Yaolong Shi Nannan Wang Yanping Wang Yongyan | 2020 | Journal of Traditional Chinese Medicine2020，40，6： | 2 |
| 12 | Development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia显示文摘Hepatic cholesterol accumulation is an important contributor to hypercholesterolemia,which results in atherosclerosis and cardiovascular disease(CVD).ATP-citrate lyase(ACLY)is a key lipogenic enzyme that converts cytosolic citrate derived from tricarboxylic acid cycle(TCA cycle)to acetyl-CoA in the cytoplasm.Therefore,ACLY represents a link between mitochondria oxidative phosphorylation and cytosolic de novo lipogenesis.In this study,we developed the small molecule 326E with an enedioic acid structural moiety as a novel ACLY inhibitor,and its CoA-conjugated form 326E-CoA inhibited ACLY activity with an IC_(50)=5.31±1.2μmol/L in vitro.326E treatment reduced de novo lipogenesis,and increased cholesterol efflux in vitro and in vivo.326E was rapidly absorbed after oral administration,exhibited a higher blood exposure than that of the approved ACLY inhibitor bempedoic acid(BA)used for hypercholesterolemia.Chronic 326E treatment in hamsters and rhesus monkeys resulted in remarkable improvement of hyperlipidemia.Once daily oral administration of 326E for 24 weeks prevented the occurrence of atherosclerosis in ApoE^(-/-)mice to a greater extent than that of BA treatment.Taken together,our data suggest that inhibition of ACLY by 326E represents a promising strategy for the treatment of hypercholesterolemia. | Zhifu Xie Mei Zhang Qian Song Long Cheng Xinwen Zhang Gaolei Song Xinyu Sun Min Gu Chendong Zhou Yangming Zhang Kexin Zhu Jianpeng Yin Xiaoyan Chen Jingya Li Fajun Nan | 2023 | Acta Pharmaceutica Sinica B2023，13，2： | 1 |
| 13 | Shale oil enrichment evaluation and production law in Gulong Sag,Songliao Basin,NE China显示文摘Based on the results of drilling,tests and simulation experiments,the shales of the Cretaceous Qingshankou Formation in the Gulong Sag of the Songliao Basin are discussed with respect to hydrocarbon generation evolution,shale oil occurrence,and pore/fracture evolution mechanism.In conjunction with a substantial amount of oil testing and production data,the Gulong shale oil enrichment layers are evaluated and the production behaviors and decline law are analyzed.The results are drawn in four aspects.First,the Gulong shales are in the stage of extensive hydrocarbon expulsion when R_(0) is 1.0%-1.2%,with the peak hydrocarbon expulsion efficiency of 49.5%approximately.In the low-medium maturity stage,shale oil migrates from kerogen to rocks and organic pores/fractures.In the medium-high maturity stage,shale oil transforms from adsorbed state to free state.Second,the clay mineral intergranular pores/fractures,dissolution pores,and organic pores make up the majority of the pore structure.During the transformation,clay minerals undergo significant intergranular pore/fracture development between the minerals such as illite and illite/smectite mixed layer.A network of pores/fractures is formed by organic matter cracking.Third,free hydrocarbon content,effective porosity,total porosity,and brittle mineral content are the core indicators for the evaluation of shale oil enrichment layers.Class-I layers are defined as free hydrocarbon content equal or greater than 6.0 mg/g,effective porosity equal or greater than 3.5%,total porosity equal or greater than 8.0%,and brittle mineral content equal or greater than 50%.It is believed that the favourable oil layers are Q2-Q3 and Q8-Q9.Fourth,the horizontal wells in the core area of the light oil zone exhibit a high cumulative production in the first year,and present a hyperbolic production decline pattern,with the decline index of 0.85-0.95,the first-year decline rate of 14.5%-26.5%,and the single-well estimated ultimate recovery(EUR)greater than 2.0×10^(4)t.In practical exploration and production,more efforts will be devoted to the clarification of hydrocarbon generation and expulsion mechanisms,accurate testing of porosity and hydrocarbon content/phase of shale under formation conditions,precise delineation of the boundary of enrichment area,relationship between mechanical properties and stimulated reservoir volume,and enhanced oil recovery,in order to improve the EUR and achieve a large-scale,efficient development of shale oil. | SUN Longde CUI Baowen ZHU Rukai WANG Rui FENG Zihui LI Binhui ZHANG Jingya GAO Bo WANG Qingzhen ZENG Huasen LIAO Yuanhui JIANG Hangl | 2023 | Petroleum Exploration and Development2023，50，3： | 1 |
| 14 | Analysis of Formation and Mechanisms of Black and Smelly River Water in Island Cities显示文摘The causes of formation of black and smelly river water were summarized,including the entry of organic pollutants into rivers,such as domestic waste,three industrial wastes,thermal pollution caused by industrial hot drainage,pollution of the river bottom and resuspension movement,and so on. The existing modes and valence changes of iron,sulfur and other elements in black and smelly water were discussed. It is clear that the formation of the black and stink is mainly caused by blackening factors and stink-causing factors. It is concluded that the main blackening factors are ferrous sulfide,manganese sulphide,and the main stink-causing factors are hydrogen sulfide,ammonia or sulfides( VOSCs),josamidine and 2-dimethyl isobenol based on sulfur elements. It provides theoretical reference for the control of black and smelly river water in island cities. | Wang Peng Weng Yisong Zhuang Pingfang Liu Mei Sun Jingya Zhang Fusheng | 2018 | Meteorological and Environmental Research2018，9，6： | 1 |
| 15 | Effects of Phosphorus Concentration on the Treatment of Domestic Wastewater by a Combination of Hydrolytic Acidification and Biological Aerated Filter Filled with Mussel Shells显示文摘The combination of hydrolytic acidification and biological aerated filter( BAF) filled with mussel shells was used to treat domestic wastewater,and the removal rates of chemical oxygen demand( COD),ammonia nitrogen( NH_3-N) and total phosphorus( TP) by the system were analyzed under different TP concentrations. When TP concentration ranged from 12. 39 to 14. 69 mg / L,the removal rate of COD was the best,over 90. 92%; as TP concentration varied from 2. 26 to 2. 61 mg / L,the removal rates of NH_3-N and TP were the best,up to 100. 00% and76. 38% respectively. The results show that it is feasible to use mussel shells as the media of BAF,and TP concentration has certain influence on the performance of the system dealing with domestic wastewater. | Sun Huiling Liu Mei Chen Qingguo Rong Zhenying Jiang Yu Sun Jingya | 2016 | Meteorological and Environmental Research2016，7，1： | 1 |
| 16 | Microbial electrolysis cells with biocathodes and driven by microbial fuel cells for simultaneous enhanced Co(Ⅱ) and Cu(Ⅱ) removal显示文摘 | Jingya SHEN Yuliang SUN Liping HUANG Jinhui YANG | 2015 | Frontiers of Environmental Science & Engineering2015，9，6： | 1 |
| 17 | Overexpression ofGbERF confers alteration of ethylene-responsive gene expression and enhanced resistance toPseudomonas syringae in transgenic tobacco显示文摘 | Jie Qin Kaijing Zuo Jingya Zhao Hua Ling Youfang Cao Chengxiang Qiu Fupeng Li Xiaofen Sun Kexuan Tang | 2006 | Journal of Biosciences2006，，2： | 1 |
| 18 | Selective hydrodechlorination of 1,2-dichloroethane to ethylene over Pd-Ag/Al2O3catalysts prepared by surface reduction显示文摘 | Han Yuiang Gu Guangfeng Sun Jingya | 2015 | Applied Surface Science2015，355，： | 1 |
| 19 | Coupling of Adhesion and Anti‑Freezing Properties in Hydrogel Electrolytes for Low‑Temperature Aqueous‑Based Hybrid Capacitors显示文摘Solid-state zinc-ion capacitors are emerging as promising candidates for large-scale energy storage owing to improved safety,mechanical and thermal stability and easy-to-direct stacking.Hydrogel electrolytes are appealing solid-state electrolytes because of eco-friendliness,high conductivity and intrinsic flexibility.However,the electrolyte/electrode interfacial contact and anti-freezing properties of current hydrogel electrolytes are still challenging for practical applications of zinc-ion capacitors.Here,we report a class of hydrogel electrolytes that couple high interfacial adhesion and anti-freezing performance.The synergy of tough hydrogel matrix and chemical anchorage enables a well-adhered interface between hydrogel electrolyte and electrode.Meanwhile,the cooperative solvation of ZnCl2 and LiCl hybrid salts renders the hydrogel electrolyte high ionic conductivity and mechanical elasticity simultaneously at low temperatures.More significantly,the Zn||carbon nanotubes hybrid capacitor based on this hydrogel electrolyte exhibits low-temperature capacitive performance,delivering high-energy density of 39 Wh kg^(-1)at-60°C with capacity retention of 98.7%over 10,000 cycles.With the benefits of the well-adhered electrolyte/electrode interface and the anti-freezing hydrogel electrolyte,the Zn/Li hybrid capacitor is able to accommodate dynamic deformations and function well under 1000 tension cycles even at-60°C.This work provides a powerful strategy for enabling stable operation of low-temperature zinc-ion capacitors. | Jingya Nan Yue Sun Fusheng Yang Yijing Zhang Yuxi Li Zihao Wang Chuchu Wang Dingkun Wang Fuxiang Chu Chunpeng Wang Tianyu Zhu Jianchun Jiang | 2024 | Nano-Micro Letters2024，16，2： | 0 |
| 20 | EMPOWERMENT IN ACTION显示文摘XinjiangUygurAutonomous Region is a vital gatewaytofurther connect China with the West.In recent years,the region has embraced a new phase of development,aligning with the country's broader development strategy.Xinjiang's focus has been on harmonizing economic growth with social stability and enhancing the quality of life for its residents.This approach prioritizes high-quality development,which highlights innovation,efficiency and sustainability,and underscores the importance of long-term initiatives aimed at ensuring lasting peace and security. | Xiao Junyong Sun Jingya | 2024 | Beijing Review2024，67，12： | 0 |
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