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| 1 | Purification and Characterization of a Mannose-binding Lectin from the Rhizomes of Aspidistra elatior Blume with Antiproliferative Activity显示文摘有一个新奇 N 终端氨基酸序列的凝集素被硫酸铵降水,离子交换层析 ondiethylaminoethyl-Sepharose 和 carboxymethyl-Sepharose 和凝胶过滤层析 onSephacryl S-100 从蜘蛛抱蛋 elatior 布鲁坶的根茎净化。A。elatior 布鲁坶凝集素(AEL ) 是有 56kDa 的一个分子的团的 heterotetramer 并且一起由 13.5 kDa 和 14.5 kDaheld 的二不同多肽组成由的二 homodimers 创作非共有原子价相互作用。Hapten 抑制试金显示向兔子红血球的 AEL 的那项 hemagglutinating 活动能被 D 甘露糖禁止,甘露聚糖, thyroglobulinand ovomucoid。凝集素是稳定的直到 70 ° C,并且在 7.0-8.0 的一个狭窄的 pH 范围显示出最大的活动。化学修正和光谱分析显示色氨酸,精氨酸,半胱氨酸和 carboxyl 组织残余为它的 hemagglutinating 活动是必要的。然而,他们可能不在活跃中心是在场的,除了一些 carboxyl 组残余。AEL 也出现了在向 Bre-04 (66%) 的 antiproliferative 活动, Lu-04 (60%) 和人的癌症房间的 HepG2 (56%) 衬里的 vitro 重要。 | Xiaochao XU Chuanfang WU Chao LIU Yongting LUO Jian LI Xinping ZHAO Els Van DAMME Jinku BAO | 2007 | Acta Biochimica et Biophysica Sinica2007，39，7： | 8 |
| 2 | Ultrasonic Nondestructive Signals Processing Based on Matching Pursuit with Gabor Dictionary显示文摘The success of ultrasonic nondestructive testing technology depends not only on the generation and measurement of the desired waveform, but also on the signal processing of the measured waves. The traditional time-domain methods have been partly successful in identifying small cracks, but not so successful in estimating crack size, especially in strong backscattering noise. Sparse signal representation can provide sparse information that represents the signal time-frequency signature, which can also be used in processing ultrasonic nondestructive signals. A novel ultrasonic nondestructive signal processing algorithm based on signal sparse representation is proposed. In order to suppress noise, matching pursuit algorithm with Gabor dictionary is selected as the signal decomposition method. Precise echoes information, such as crack location and size, can be estimated by quantitative analysis with Gabor atom. To verify the performance, the proposed algorithm is applied to computer simulation signal and experimental ultrasonic signals which represent multiple backscattered echoes from a thin metal plate with artificial holes. The results show that this algorithm not only has an excellent performance even when dealing with signals in the presence of strong noise, but also is successful in estimating crack location and size. Moreover, the algorithm can be applied to data compression of ultrasonic nondestructive signal. | GUO Jinku WU Jinying YANG Xiaojun LIU Guangbin | 2011 | Chinese Journal of Mechanical Engineering2011，24，4： | 7 |
| 3 | Microstructural evolution and tensile properties of low-carbon steel with martensitic microstructure during warm deforming and annealing显示文摘For preparing large-scale nano-grained and ultrafine-grained steel sheets by warm rolling and annealing,the effects of de- forming temperature on both the flow stress and the microstructure evolution of 09MnNiD steel with lath martensitic microstructure were studied by warm-compression test and transmission electron microscopy(TEM)observation.Thereafter,the steel with the lath martensitic structure was multi-pass warm-rolled and then annealed.TEM results indicate that nano-grained and ultrafine-grained steel sheets are formed by warm rolling at 400℃and annealing at 400-600℃.In comparison with the as-warm-rolled specimen,the tensile strength at room temperature changes a little when the rolled samples are annealed below 450℃,and the tensile strength is greatly lowered as the annealing temperature increases to above 550℃. | Yuwei Gao Tianfu Jing Guiying Qiao Jinku Yu Tiansheng Wang Qun Li Xinyu Song Shuqiang Wang Hong Gao | 2008 | Journal of University of Science and Technology Beijing2008，15，3： | 4 |
| 4 | Conformational study reveals amino acid residues essential for hemagglutinating and anti-proliferative activities of Clematis montana lectin显示文摘铁线莲 montana lectin (电流型逻辑) ,从 C 净化的新奇甘露糖绑定 lectin。montana Buch 火腿茎(Ranunculaceae ) ,被证明了在肿瘤房间在兔子红血球和导致 apoptosis 活动举办 hemagglutinating 活动。然而,电流型逻辑的生物化学的性质没揭示,它的结构的信息仍然需要被阐明。在这研究,电流型逻辑拥有了相当好的 thermostability 和碱的抵抗,这被发现,并且它的 hemagglutinating 活动是二原子价的金属阳离子依赖者。另外,红血球凝聚测试和荧光光谱学证明了硫酸盐能改变的那 GuHCl,脲,和钠 dodecyl 是电流型逻辑的符合构造并且进一步引起了红血球凝聚活动的损失。而且,荧光光谱的变化显示色氨酸(Trp ) 微型环境变换可能与电流型逻辑的符合构造和 bioactivities 有关。另外, Trp 残余,精氨酸(Arg ) 残余,和 sulfhydryl 为电流型逻辑的 hemagglutinating 活动是重要的,这也被发现,但是仅仅 Trp 被证明为电流型逻辑符合构造关键。而且, Trp, Arg,和修改 sulfhydryl 的电流型逻辑展出了 97.17% , 76.99% ,和 49.64% 它的 anti-proliferative 活动的损失,分别地它与它的 hemagglutinating 活动的改变一致。给这些调查结果,电流型逻辑的表面上的 Trp 残余是必要的让活跃中心为糖类绑定形成底层可存取的符合构造和合适的环境。 | Bangmin Lu Bin Zhang Wei Qi Yanan Zhu Yan Zhao Nan Zhou Rong Sun Jinku Bao Chuanfang Wu | 2014 | Acta Biochimica et Biophysica Sinica2014，46，11： | 2 |
| 5 | Investigation on the undercooling and crystallization of pure aluminum melt by DSC 显示文摘 | Yu Jinku Qiao Qi Liu Lian | 2010 | Phase Tran sitions2010，83，7： | 1 |
| 6 | Surface nanocrystallization induced by shot peening and its effect on corrosion resistance of 1Cr18Ni9Ti stainless steel 显示文摘 | Wang Tiansheng Yu Jinku Dong Bingfeng | 2006 | Surface & Coatings Technology2006，200，： | 1 |
| 7 | Camptothecin-producing endophytic fungus Trichoderma atroviride LY357: isolation, identification, and fermentation conditions optimization for camptothecin production显示文摘 | Xiang Pu Xixing Qu Fei Chen Jinku Bao Guolin Zhang Yinggang Luo | 2013 | Applied Microbiology and Biotechnology2013，，21： | 1 |
| 8 | Surface nano-crystallization induced by shot peening and its effects on corrosion resistance of 1Cr18Ni9Ti stainless steel显示文摘 | Wang Tiansheng Yu Jinku Dong Bingfeng | 2006 | Surface&Coatings Technology2006，200，： | 1 |
| 9 | Grain size effects on effective thermal conductivity of porous materials with internal thermal contact resistance 显示文摘 | Wang Moran Wang Xinmiao Wang Jinku Pan Ning | 2013 | Journal of Porous Media2013，16，11： | 1 |
| 10 | A novel mannose-binding lectin from Liparis nervosa with anti-fungal and anti-tumor activities显示文摘Plant lectins are carbohydrate-binding proteins with nonimmune origin,which can reversibly bind with carbohydrates,agglutinate cells,and precipitate polysaccharides and glycoconjugates.Plant lectins have attracted much attention for their anti-virus,anti-proliferation,and pro-apoptosis properties.Thus the exploration of new lectins has received special attention.Here we purified a mannose-binding lectin from the rhizomes of Liparis nervosa by ion exchange chromatography on DEAE-Sepharose,affinity chromatography on Mannose-Sepharose 4B,and gel filtration chromatography on Sephacryl S-100.The purified L.nervosa lectin(LNL)was identified to be a monomeric protein with a molecular mass of 13 kDa.LNL exhibited hemagglutinating activity towards rabbit erythrocytes,and its activity could be strongly inhibited by D-mannose,N-acetyl glucosamine and thyroglobulin.In vitro experiments showed that LNL exhibited a comparable anti-fungal activity against Piricularia oryzae(Cavara),Bipolaris maydis,Fusarium graminearum,and Sclerotium rolfsii,and anti-proliferation activity against tumor cells by inducing apoptosis.The full-length cDNA sequence of LNL is 715 bp in length and contains a 525 bp open reading frame(ORF)encoding a 110-residue mature protein.It was predicted to have three mannose-binding conserved motifs‘QXDXNXVXY’.The binding pattern of LNL was further revealed by homology modeling and molecular docking.We demonstrated that LNL is not only a potential therapeutic candidate against tumor but also a new anti-fungal agent. | Na Jiang Yuqing Wang Jing Zhou Ruxiao Zheng Xiao Yuan Miaomiao Wu Jinku Bao Chuanfang Wu | 2020 | Acta Biochimica et Biophysica Sinica2020，52，10： | 1 |
| 11 | Roughness and cavitations eftects on electro-osmotic flows in rough microchannels using the lattice Poisson-Boltzmann method 显示文摘 | Moran Wang Jinku Wang Shiyi Chen | 2007 | Journal of Computational Physics2007，226，1： | 1 |
| 12 | An optimized gossypol high-performance liquid chromatography assay and its application in evaluation of different gland genotypes of cotton显示文摘 | Yingfan Cai Hong Zhang Yu Zeng Jianchuan Mo Jinku Bao Chen Miao Jie Bai Fang Yan Fang Chen | 2004 | Journal of Biosciences2004，，1： | 1 |
| 13 | Preparation of silver/hydroxy- apatite nanocomposite spheres显示文摘 | Liu Jinku Yang Xiadong Tian Xingang | 2008 | Powder Technology2008，184，： | 1 |
| 14 | Surface Nanocrystallization Induced by Shot Peening and its Effect on Corrosion Resistance of 1Cr18Ni9Ti Stainless Steel显示文摘 | Tiansheng Wang Jinku Yu Bingfeng Dong | 2006 | Surface & Coatings Technology2006，200，： | 1 |
| 15 | Superior storage stability in low lipoxygenase maize varieties显示文摘 | Jinku Li Ying Zhang Zengliang Yu Yujuan Wang Ye Yang Zheng Liu Jiayue Jiang Mei Song Yuejin Wu | 2007 | Journal of Stored Products Research2007，，4： | 1 |
| 16 | Morphologies-controlled synthesis of CaWO4 crystals by a novel supramolecular template method 显示文摘 | Liu Jinku Wu Qingsheng Ding Yaping | 2005 | Journal of Crystal Growth2005，279，： | 1 |
| 17 | Compression behavior of Zr_(41)Ti_(14)Cu_(12.5)Ni_(10)Be_(22.5) bulk metallic glass up to 24 GPa显示文摘The compression of a Zr41Ti14Cu12.5Ni10Be22.5 bulk metallic glass (BMG) is investigated at room temperature up to 24 GPa using in-situ high pressure energy dispersive X-ray diffraction with a synchrotron radiation source. The pressure-induced structural relaxation is exhibited. It is found that below about 8 GPa, the existence of excess free volume contributes to the rapid structural relaxation, which gives rise to the rapid volumetric change, and the structural relaxation results in the structural stiffness under higher pressure. | LI Gong 1, 2 , ZHAN Zaiji 2 , LIU Jing 3 , YUN Jinku 1 , SUN Liling 2 , LIU Riping 1 , ZHANG Jun 2 & WANG Wenkui 1, 2 1. Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao 066004, China 2. Center for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100080, China 3. BSRF, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100039, China | 2005 | Science China(Physics,Mechanics & Astronomy)2005，48，3： | 1 |
| 18 | Corrprehensive and Efficient Protection of Kemel Control Data显示文摘 | LI Jinku WANG Zhi BLETSCH T | 2011 | IEEE Transactions on Information Forensics and Security2011，6，4： | 1 |
| 19 | Surface nanocrystallization induced by shot peening and its effect on corrosion resistance of 1Cr18Ni9Ti stainless steel 显示文摘 | Tiansheng Wang Jinku Yu Beijngfeng Dong | 2006 | Surface &Coatings Technology2006，200，： | 1 |
| 20 | Determination of ac-tivation of energy for crystallizations in Ni-Sn-P amorphous al-loys 显示文摘 | Jinku Yu Tianfu jing Jun Yang | 2009 | Journal of Materials processing Technology2009，，： | 1 |
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