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| 1 | Enhancing mixing of particles by baffies in a rotating drum mixer显示文摘Baffies with shape of '–'(single baffle) ,'+'(cross-baffles with four arms) and ''(baffles with 6 arms) are used to enhance the mixing of particles in a rotating drum mixer. A micro-dynamics study of mixing and segregation of a bi-disperse system of two particle sizes in the rotating drum with these three kinds of baffles is carried out using the discrete element method(DEM) . The effect of the baffles on mixing,and the mechanisms of mixing enhancement by the baffles are discussed and analyzed. Simulation results show that in an unbaffled drum mixer,particle convection,particle diffusion,and size segregation of bi-disperse particles,all play important roles in the mixing process;whereas size segregation will be largely restrained when the drum mixer has a baffle,regardless of its shape,and the degree of mixing is higher than that in an unbaffled drum mixer. The different mixing characteristics for '–' shaped baffle,'+' baffle,and '' baffle are revealed by the simulation results. For '+' or '' style baffles,there is an optimal size of baffles for the mixing of particles,and the optimal mixing efficiency is higher than that for '–' baffle. | Maoqiang Jiang Yongzhi Zhao Gesi Liu Jinyang Zheng | 2011 | Particuology2011,9,3: | 26 |
| 2 | Liquid bridge force between two unequal-sized spheres or a sphere and a plane显示文摘Liquid bridge force acting between wet particles is an important property in particle characterization. This paper deals with liquid bridge force between either two unequal-sized spherical particles or a sphere and a flat plate under conditions where gravitational effect arising from bridge distortion is negligible. In order to calculate the force of the liquid bridge efflciently and accurately, expressions of liquid conflguration and liquid bridge force were derived by building a mechanical model, which assumes the liquid bridge to be circular in shape between either two unequal-sized spheres or a sphere and a plane. To assess the accuracy of the numerical results of the calculated liquid bridge forces, they were compared to the published experimental data. | Youchuan Chen Yongzhi Zhao Hongli Gao Jinyang Zheng | 2011 | Particuology2011,9,4: | 11 |
| 3 | miR-145 improves metabolic inflammatory disease through multiple pathways显示文摘Chronic inflammation plays a pivotal role in insulin resistance and type 2 diabetes,yet the mechanisms are not completely understood.Here,we demonstrated that serum LPS levels were significantly higher in newly diagnosed diabetic patients than in normal control.miR-145 level in peripheral blood mononuclear cells decreased in type 2 diabetics.LPS repressed the transcription of miR-143/145 cluster and decreased miR-145 levels.Attenuation of miR-145 activity by anti-miR-145 triggered liver inflammation and increased serum chemokines in C57BL/6 J mice.Conversely,lentivirus-mediated miR-145 overexpression inhibited macrophage infiltration,reduced body weight,and improved glucose metabolism in db/db mice.And miR-145 overexpression markedly reduced plaque size in the aorta in ApoE−/−mice.Both OPG and KLF5 were targets of miR-145.miR-145 repressed cell proliferation and induced apoptosis partially by targeting OPG and KLF5.miR-145 also suppressed NF-κB activation by targeting OPG and KLF5.Our findings provide an association of the environment with the progress of metabolic disorders.Increasing miR-145 may be a new potential therapeutic strategy in preventing and treating metabolic diseases such as type 2 diabetes and atherosclerosis. | Min He Nan Wu Man Cheong Leong Weiwei Zhang Zi Ye Rumei Li Jinyang Huang Zhaoyun Zhang Lianxi Li Xiao Yao Wenbai Zhou Naijia Liu Zhihong Yang Xuehong Dong Yintao Li Lili Chen Qin Li Xuanchun Wang Jie Wen Xiaolong Zhao Bin Lu Yehong Yang Qinghua Wang Renming Hu | 2020 | Journal of Molecular Cell Biology2020,12,2: | 7 |
| 4 | Transition of axial segregation patterns in a long rotating drum显示文摘Axial segregation of a bidisperse mixture of particles in a long rotating drum is studied using the discrete element method. Simulation results show that particle interaction is responsible for axial segregation,the patterns of which are influenced by the end wall effect. Axial segregation patterns transform under competing influences of the end walls and the particle interaction forces. The two influential factors vary with various rotational speeds and end wall friction levels. The result is the transition of different axial segregation patterns: two large-particle bands at both ends, two small-particle bands at both ends, or a random segregation pattern where either a large-particle band or small-particle band may appear at either end. | Zequn Cui Yongzhi Zhao Youchuan Chen Xiao Liu Zhengli Hua Chilou Zhou Jinyang Zheng | 2014 | Particuology2014,12,2: | 6 |
| 5 | Longitudinal-vertical integrated sliding mode controller for distributed electric vehicles显示文摘Dear editor,In the recent years,with the advancements in vehicular technology,the vehicle dynamics control has attracted considerable research attention[1,2].Many active stability control systems have played a significant role in the chassis control of electric vehicles(EV),promising upgraded,more secure. | Yan MA Jinyang ZHAO Haiyan ZHAO Hong CHEN Tielong SHEN | 2020 | Science China(Information Sciences)2020,63,11: | 2 |
| 6 | An erosion model for the discrete element method显示文摘 | Yongzhi Zhao Huacling Ma Lei Xu Jinyang Zheng | 2017 | Particuology2017,15,5: | 2 |
| 7 | Rapid phenotypic evolution with shallow genomic differentiation during early stages of high elevation adaptation in Eurasian Tree Sparrows显示文摘Known as the‘third polar region’,the Qinghai-Tibet Plateau represents one of the harshest highland environments in the world and yet a number of organisms thrive there.Previous studies of birds,animals and humans have focused on well-differentiated populations in later stages of phenotypic divergence.The adaptive processes during the initial phase of highland adaptation remain poorly understood.We studied a human commensal,the Eurasian Tree Sparrow,which has followed human agriculture to the Qinghai-Tibet Plateau.Despite strong phenotypic differentiation at multiple levels,in particular in muscle-related phenotypes,highland and lowland populations show shallow genomic divergence and the colonization event occurred within the past few thousand years.In a one-month acclimation experiment investigating phenotypic plasticity,we exposed adult lowland tree sparrows to a hypoxic environment and did not observe muscle changes.Through population genetic analyses,we identified a signature of polygenic adaptation,whereby shifts in allele frequencies are spread across multiple loci,many of which are associated with muscle-related processes.Our results reveal a case of positive selection in which polygenic adaptation appears to drive rapid phenotypic evolution,shedding light on early stages of adaptive evolution to a novel environment. | Yanhua Qu Chunhai Chen Ying Xiong Huishang She Yong E Zhang Yalin Cheng Shane DuBay Dongming Li Per G P Ericson Yan Hao Hongyuan Wang Hongfeng Zhao Gang Song Hailin Zhang Ting Yang Chi Zhang Liping Liang Tianyu Wu Jinyang Zhao Qiang Gao Weiwei Zhai Fumin Lei | 2020 | National Science Review2020,7,1: | 2 |
| 8 | Methane emissions from a rice agroecosystem in South China: Effects of water regime, straw incorporation and nitrogen fertilizer显示文摘 | Jinyang Wang Xiaolin Zhang Zhengqin Xiong M. Khalil Xu Zhao Yingxin Xie Guangxi Xing | 2012 | Nutrient Cycling in Agroecosystems2012,,1: | 2 |
| 9 | Interfacial Degradation and Optimization of Li-rich Cathode Materials显示文摘High-energy and safe lithium ion batteries(LIBs)are in increasing need as the rapid development of electronic devices,electric vehicles,as well as energy storage station.Li-rich oxides have attracted a lot of attention due to their high capacity and low cost as cathode material for LIBs.However,they still suffer from the vulnerable cathode/electrolyte interface,which presents the huge challenges of surface degradation and gas release,particularly at high state of charge.Some issues of Li-rich cathode materials,such as moderate cycle stability and voltage decay,are in tight connection with electrode-electrolyte interfacial side reactions.Research in the area of interfacial degradation mechanism and optimization strategies is of great significance as for Li-rich cathode,and extensive efforts have been poured.This review aims to understand the degradation mechanism of Li-rich cathode materials,and summarize the corresponding valuable and effective optimization strategies.Based on these considerations,we also have discussed the remaining challenges and the future research direction. | Yuefeng Su Jiayu Zhao Lai Chen Ning Li Yun Lu Jinyang Dong Youyou Fang Shi Chen Feng Wu | 2021 | Chinese Journal of Chemistry2021,39,2: | 1 |
| 10 | Numerical simulation of temperature rise within hydrogen vehicle cylinder during refueling显示文摘 | Lei Zhao Yanlei Liu Jian Yang Yongzhi Zhao Jinyang Zheng Haiyan Bie Xianxin Liu | 2010 | International Journal of Hydrogen Energy2010,,15: | 1 |
| 11 | An optimized control method for a high utilization ratio and fast filling speed in hydrogen refueling stations显示文摘 | Jinyang Zheng Jianjun Ye Jian Yang Ping Tang Lei Zhao Maradee Kern | 2009 | International Journal of Hydrogen Energy2009,,7: | 1 |
| 12 | Study on Metal Flow in Continuous Extrusion Cladding of Cable Alumi- num Sheath Using FEM Analysis显示文摘 | Ying Zhao Baoyun Song Jinyang Pei | 2011 | Advanced Materials Research2011,,: | 1 |
| 13 | Development of high pressure gaseous hydrogen storage technologies显示文摘 | Jinyang Zheng Xianxin Liu Ping Xu Pengfei Liu Yongzhi Zhao Jian Yang | 2011 | International Journal of Hydrogen Energy2011,,1: | 1 |
| 14 | Screening Linear and Circular RNA Transcripts from Stress Granules显示文摘Stress granules(SGs)are cytoplasmic ribonucleoprotein assemblies formed under stress conditions and are related to various biological processes and human diseases.Previous studies have reported the regulatory role of some proteins and linear RNAs in SG assembly.However,the relationship between circular RNAs(circRNAs)and SGs has not been discovered.Here,we screened both linear RNAs and circRNAs in SGs using improved total RNA sequencing of purified SG cores in mammalian cells and identified circular transcripts specifically localized in SGs.circRNAs with higher SG-related RNA-binding protein(RBP)binding abilities are more likely to be enriched in SGs.Furthermore,some SG-enriched circRNAs are differentially expressed in hepatocellular carcinoma(HCC)and adjacent tissues.These results suggest the regulatory role of circRNAs in SG formation and provide insights into the biological function of circRNAs and SGs in HCC. | Shuai Chen Jinyang Zhang Fangqing Zhao | 2023 | Genomics, Proteomics & Bioinformatics2023,21,4: | 1 |
| 15 | Efficient production of optically pure l-lactic acid from food waste at ambient temperature by regulating key enzyme activity 显示文摘 | Xiang Liab Yinguang Chenb Shu Zhao Hong Chena Xiong Zhengb Jinyang Luob Yanan Liua | 2015 | Water Research2015,70,5: | 1 |
| 16 | Ag/epoxy nanocomposite film with aligned Ag nanowires and their polarization property显示文摘 | Jinyang Feng Xiao Ma Haibo Mao Baoshun Liu Xiujian Zhao | 2011 | Journal of Materials Research2011,,: | 1 |
| 17 | Nonlinear dynamic analysis on rigid-flexible coupling system of an elastic beam显示文摘Previous work examined the effect of the attached stiffness matrix terms on stability of an elastic beam undergoing prescribed large overall motion.The aim of the present work is to extend the nonlinear formulations to an elastic beam with free large overall motion.Based on initial stress method,the nonlinear coupling equations of elastic beams are obtained with free large overall motion and the attached stiffness matrix is derived by solving sub-static formulation.The angular velocity and the tip deformation of the elastic pendulum are calculated.The analytical results show that the simulation results of the present model are tabled and coincide with the one-order approximate model.It is shown that the simulation results accord with energy conservation principle. | Feiyun Zhao Jinyang Liu Jiazhen Hong | 2012 | Theoretical & Applied Mechanics Letters2012,2,2: | 1 |
| 18 | Levelized costs of the energy chains of new energy vehicles targeted at carbon neutrality in China显示文摘The diffusion of new energy vehicles(NEVs),such as battery electric vehicles(BEVs)and fuel cell vehicles(FCVs),is critical to the transportation sector's deep decarbonization.The cost of energy chains is an important factor in the diffusion of NEVs.Although researchers have addressed the technological learning effect of NEVs and the life cycle emissions associated with the diffusion of NEVs,little work has been conducted to analyze the life cycle costs of different energy chains associated with different NEVs in consideration of technological learning potential.Thus,relevant information on investment remains insufficient to promote the deployment of NEVs.This study proposes a systematic framework that includes various(competing or coordinated)energy chains of NEVs formed with different technologies of power generation and transmission,hydrogen production and transportation,power-to-liquid fuel,and fuel transportation.The levelized costs of three typical carbon-neutral energy chains are investigated using the life cycle cost model and considering the technological learning effect.Results show that the current well-to-pump levelized costs of the energy chains in China for BEVs,FCVs,and internal combustion engine vehicles(ICEVs)are approximately 3.60,4.31,and 2.21 yuan/GJ,respectively,and the well-to-wheel levelized costs are 4.50,6.15,and 7.51 yuan/GJ,respectively.These costs primarily include raw material costs and they vary greatly for BEVs and FCVs from resource and consumer costs.In consideration of the technological learning effect,the energy chains'well-to-wheel levelized costs are expected todecrease by 24.82%for BEVs,27.12%for FCVs,and 19.25%for ICEVs by 2060.This work also summarizes policy recommendations on developing energy chains to promote the diffusion of NEVs in China. | Xiaohan QIU Jinyang ZHAO Yadong YU Tieju MA | 2022 | Frontiers of Engineering Management2022,9,3: | 0 |
| 19 | IDH1突变体通过抑制JNK的激活减少生长因子缺失诱导的细胞凋亡显示文摘文章简介抵抗凋亡和能在血清营养因子缺乏的情况下生长是肿瘤细胞的两个主要特征。JNK的激活是血清饥饿诱导的细胞凋亡所必须的因素。目前研究表明IDH1突变体产生的致癌代谢物2-羟基戊二酸(2-HG)是突变的导致肿瘤形成的主要原因。 | Bin Jiang Jia Zhang Jinmei Xia Wentao Zhao Yanan Wu Minggang Shi Lianzhong Luo Huamin Zhou Ai Chen Huanhuan Ma Qingwen Zhao Muhammad Suleman Furong Lin Lin Zhou Jinyang Wang Yan Zhang Ying He Xiaotong Li Li-Man Hung Tak Wah Mak 李勤喜 | 2018 | 科学新闻2018,0,4: | 0 |
| 20 | The authors acknowledge the financial support from the National Natural Science Foundation of China(project No.31971247).显示文摘Mineralized tissue regeneration is an important and challenging part of the field of tissue engineering and regeneration.At present,autograft harvest procedures may cause secondary trauma to patients,while bone scaffold materials lack osteogenic activity,resulting in a limited application.Loaded with osteogenic induction growth factor can improve the osteoinductive performance of bone graft,but the explosive release of growth factor may also cause side effects.In this study,we innovatively used platelet-rich fibrin(PRF)-modified bone scaffolds(Bio-Oss®)to replace autograft,and used cytokine(BMP-2)to enhance osteogenesis.Encouragingly,this mixture,which we named“Autograft Mimic(AGM)”,has multiple functions and advantages.(1)The fiber network provided by PRF binds the entire bone scaffold together,thereby shaping the bone grafts and maintaining the space of the defect area.(2)The sustained release of BMP-2 from bone graft promoted bone regeneration continuously.(3)AGM recruited bone marrow mesenchymal stem cells(BMSCs)and promote their proliferation,migration,and osteogenic differentiation.Thus,AGM developed in this study can improve osteogenesis,and provide new guidance for the development of clinical bone grafts. | Yan Wei Guixin Zhu Zifan Zhao Chengcheng Yin Qin Zhao Hudi Xu Jinyang Wang Jinglun Zhang Xiaoxin Zhang Yufeng Zhang Haibin Xia | 2021 | International Journal of Oral Science2021,13,2: | 0 |