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| 1 | Chinese Stroke Center Alliance:a national effort to improve healthcare quality for acute stroke and transient ischaemic attack:rationale,design and preliminary findings显示文摘Background In June 2015,the Chinese Stroke Association(CSA)initiated the Chinese Stroke Center Alliance(CSCA)to establish the national hospital-based stroke care quality assessment and improvement platform.This article outlines its objectives,operational structure,patient population,quality improvement(QI)intervention tools,data elements,data collection methodology and current patient and hospital data.Methods The CSCA is a national,hospital-based,multicentre,voluntary,multifaceted intervention and continuous QI initiative.This multifaceted intervention includes stroke centre development,written care protocols,workshops and a monitoring/feedback system of evidencebased performance measures.The data coordinating centre of the CSCA resides at the China National Clinical Research Center for Neurological Diseases,Beijing Tiantan Hospital.results As of July 2017,1576 hospitals in China have contributed detailed clinical information to serve as a benchmark for the stroke care quality of 433264 patients with acute stroke/transient ischaemic attacks(TIA),including 352572(81.38%)acute ischaemic stroke,30362(7.01%)TIA,42080(9.71%)spontaneous intracranial haemorrhage,5505(1.27%)subarachnoid haemorrhage and 2745(0.63%)not specified stroke.Conclusion The CSCA programme is designed to establish a continuous national stroke registry and help healthcare providers develop stroke centres and treat patients in a consistent manner in accordance with accepted national guidelines and,ultimately,improve patient outcomes.It supports the CSA mission to reduce stroke burden in China. | Yongjun Wang Zixiao Li Yilong Wang Xingquan Zhao Liping Liu Xin Yang Caiyun Wang Hongqiu Gu Fuying Zhang Chunjuan Wang Ying Xian David Z Wang Qiang Dong Anding Xu Jizong Zhao Chinese Stroke Center Alliance investigators | 2018 | Stroke & Vascular Neurology2018，3，4： | 38 |
| 2 | Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth显示文摘发信号的调停肽的 cell-to-cell 在植物在细胞的功能的协作和定义有关键角色。肽受体匹配为理解位于调停肽的发信号下面的机制是重要的。这里,我们报导根分裂组织生长的指导结构的鉴定为植物开发重要的因素(RGF ) 受体。基于签名 ligand 识别,主题(Arg-x-Arg ) 在充满白氨酸的重复受体 kinases (LRR-RKs ) 的一个亚科保存了的试金识别了机能上地 uncharacterized LRR-RK At4g26540 作为 RGF1 (RGFR1 ) 的受体。我们进一步在 2.6 Å 的一个决定与 RGFR1 的 LRR 领域在建筑群解决了 RGF1 的水晶结构;,它表明 Arg-x-Gly-Gly (RxGG ) 主题为由 RGFR1 的 RGF1 的硫酸盐组的特定的识别负责。基于 RxGG 主题,我们识别了另外四 RGFR。在导致 RGF 的发信号的五 RGFR 的参予被生物化学、基因的数据支持。我们也提供证明 SERK 为 RGF 作为合作受体工作的证据。一起拿,我们的学习识别 RGF 受体,能连接 RGF 的合作受体与他们的下游的部件发信号并且为与他们的肽 ligands 的 LRR-RKs 的基于结构的匹配提供原则的一个证明。 | Wen Song Li Liu Jizong Wang Zhen Wu Heqiao Zhang Jiao Tang Guangzhong Lin Yichuan Wang Xing Wen Wenyang Li Zhifu Han Hongwei Guo Jijie Chai | 2016 | Cell Research2016，26，6： | 20 |
| 3 | Enhancement Expression of bFGF in Chinese Patients with Moyamoya Disease显示文摘Objective To detect the content of the basic fibroblast growth factor in blood samples of patients with Moyamoya disease, and investigate the relationship between Moyamoya disease and the basic fibroblast growth factor. Methods This tissue microarray study included 24 cases of superficial temporal artery samples, 15 cases of Moyamoya disease, and 9 cases of normal arteries as control, and bFGF immunofluorescence assay was applied to test the samples. The number of positive cells and total cells of the muscular layer and the endothelium layer were counted separately in every picture, the positive rates were calculated, and the experimental data were analyzed statistically. Results The bFGF immunofluorescence staining of smooth muscular layer cells, intima cells and endothelial cells from the moyamoya disease group were obviously stronger than that from the control group (P<0.01). Conclusion The enhancement expression of bFGF in the Moyamaya disease group implicates that bFGF plays an important part in the pathogenesis of Moyamoya disease. | ZOU DeWei ZHAO JiZong ZHANG Dong WANG Shuo WANG KeDa ZHANG Yan | 2011 | Biomedical and Environmental Sciences2011，24，1： | 12 |
| 4 | SERK Family Receptor-like Kinases Function as Co-receptors with PXY for Plant Vascular Development显示文摘 | Heqiao Zhang Xiaoya Lin Zhifu Han Jizong Wang Li-Jia Qu Jijie Chai | 2016 | Molecular Plant2016，9，10： | 11 |
| 5 | Molecular actions of NLR immune receptors in plants and animals显示文摘NLRs constitute intracellular immune receptors in both plants and animals. Direct or indirect ligand recognition results in formation of oligomeric NLR complexes to mediate immune signaling. Over the past 20 years, rapid progress has been made in our understanding of NLR signaling. Structural and biochemical studies provide insight into molecular basis of autoinhibition,ligand recognition, and resistosome/inflammasome formation of several NLRs. In this review, we summarize these studies focusing on the structural aspect of NLRs. We also discuss the analogies and differences between plant and animal NLRs in their mechanisms of action and how the available knowledge may shed light on the signaling mechanisms of other NLRs. | Jizong Wang Jijie Chai | 2020 | Science China(Life Sciences)2020，63，9： | 9 |
| 6 | Disorders of Consciousness in China显示文摘With the development of modern international medicine, the subject of disorders of consciousness(DOCs)has begun to be raised in China's Mainland. Much progress has been made to date in several specialties related to the management of chronic DOC patients in China. In this article, we briefly review the present status of DOC studies in China, specifically concerning diagnosis, prognosis,therapy, and rehabilitation. The development of DOCrelated scientific organizations and activities in China are introduced. Some weaknesses that need improvement are also noted. The current program provides a good foundation for future development. | Jizong Zhao | 2018 | Neuroscience Bulletin2018，34，4： | 7 |
| 7 | Early postoperative infarction out of the middle cerebral artery distribution following superficial temporal artery-middle cerebral artery bypass: clinical features and pathogenesis显示文摘The extracranial-intracranial (EC-IC) bypass surgery has been widely used in the treatment of cerebral ischemia,intracranial aneurysms,and other diseases for more than 40 years.In terms of treating atherosclerotic cerebral ischemia,the surgery is presumed to be helpful for the subgroup of hemodynamic compromise in prevention of subsequent stroke.However,two multicenter trials presented with high perioperative stroke rate and failed to demonstrate the profit of the surgery.1-3 On this point,one of the crucial issues currently is how to lower down the perioperative stroke rate,the centerpiece of which is early postoperative infarction (EPI). | Zhang Dong Huang Zhenhua Zhao Jizong | 2014 | Chinese Medical Journal2014，，11： | 5 |
| 8 | Gene expression profiles in intracranial aneurysms显示文摘In this study, we extracted total RNA from 15 intracranial aneurysms and 17 superficial temporal artery samples, then performed genome-wide expression profiling using the Affymetrix U133 Plus 2.0 GeneChip. Genes that were differentially expressed between intracranial aneurysms and arterial samples were identified using significance analysis for microarrays, and the expression patterns of three randomly-selected genes were verified by real-time polymerase chain reaction analysis. We identified 3 736 differentially-expressed genes out of the 47 000 assayed transcripts. A total of 179 genes showed a >10-fold change in expression between the aneurysms and the arterial samples. Genes involved in the proliferation, migration, and apoptosis of vascular muscle cells, atherosclerosis, extracellular matrix disruption, and inflammatory reactions were associated with the formation of intracranial aneurysms. There were no significant differences in gene expression profile between unruptured and ruptured aneurysms. | Lanbing Yu Jinghan Fan Shuo Wang Dong Zhang Rong Wang Yuanli Zhao Jizong Zhao | 2014 | Neuroscience Bulletin2014，30，1： | 3 |
| 9 | Combination of intraoperative embolisation with surgical resection for treatment of giant cerebral arteriovenous malformations显示文摘 | Shuo W jingshen L | 2000 | J Clin Neurosci2000，7，1： | 1 |
| 10 | Structure, biochemical function, and signaling mechanism of plant NLRs显示文摘To counter pathogen invasion,plants have evolved a large number of immune receptors,including membrane-resident pattern recognition receptors(PRRs)and intracellular nucleotide-binding and leucine-rich repeat receptors(NLRs).Our knowledge about PRR and NLR signaling mechanisms has expanded significantly over the past few years.Plant NLRs form multi-protein complexes called resistosomes in response to pathogen effectors,and the signaling mediated by NLR resistosomes converges on Ca2+-permeable channels.Ca2+-permeable channels important for PRR signaling have also been identified.These findings highlight a crucial role of Ca2+in triggering plant immune signaling.In this review,we first discuss the structural and biochemical mechanisms of non-canonical NLR Ca2+channels and then summarize our knowledge about immune-related Ca2+-permeable channels and their roles in PRR and NLR signaling.We also discuss the potential role of Ca2+in the intricate interaction between PRR and NLR signaling. | Jizong Wang Wen Song Jijie Chai | 2023 | Molecular Plant2023，16，1： | 1 |
| 11 | Osteochondral defect repair by deminerialized cortical bone matrix显示文摘 | Gao Jizong MD PHD Knank Divid PHD Goldberg Victor M MD | 2004 | Clin Orthop2004，，427： | 1 |
| 12 | The dy- namic in vivo distribμtion of bone marrow-derived mes- enchymal stem ceils after infusion显示文摘 | Jizong Gao James E Dennis Raymond F | 2001 | Cells Tissues Organs2001，169，2： | 1 |
| 13 | Clinical characteristics and surgical result of patients with cerebral arteriovenous malformations显示文摘 | Zhao Jizong Wang Shuo Li Jingsheng | 2005 | Surgical Neurology2005，63，2： | 1 |
| 14 | Combination of intraoperative embolisation with surgical resection for treatment of giant cerebral arteriovenous malformations显示文摘 | Jizong Z Shuo W Jingshen L | 2000 | J Clin Neurosci2000，7，1： | 1 |
| 15 | Preparation and char- acterization of bio-oil modified urea-formaldehyde wood adhe- sives显示文摘 | Li Ben Zhang Jizong Ren Xueyong | 2014 | Bio Resources2014，9，3： | 1 |
| 16 | Stabilization of quantized systems based on Kalman filter显示文摘 | Yuanqing Xia Jingjing Yan Jizong Shang Mengyin Fu Bo Liu | 2012 | Control Engineering Practice2012，，10： | 1 |
| 17 | Clinical evalution of minimally invasive neurosurgery 显示文摘 | ZHAO Jizong ZHANG Maozhi YANG Jun | 2002 | Chin J of Neurosurg Dis Res2002，1，1： | 1 |
| 18 | Treatment of deep lesions in brain by minimally invasive neurosurgery 显示文摘 | ZHAO Jizong NI Ming | 2002 | Chin J of Neurosurg Dis Res2002，1，4： | 1 |
| 19 | Clinical characteristics and surgical result of patients with cerebral arteriovenous malformations 显示文摘 | Zhao Jizong Wang Shuo Li Jingsheng | 2005 | Surgical Neurology2005，63，2： | 1 |
| 20 | CoB and BN composites enabling integrated adsorption/catalysis to polysulfides for inhibiting shuttle-effect in Li-S batteries显示文摘Lithium-sulfur(Li-S)batteries are hampered by the infamous shuttle effect and slow redox kinetics,resulting in rapid capacity decay.Herein,a bifunctional catalysis CoB/BN@rGO with integrated structure and synergy effect between adsorption and catalysis is proposed to solve the above problems.The integrated CoB and BN are simultaneously and uniformly introduced on the rGO substrate through a one-step calcination strategy,applied to modify the cathode side of PP separator.The transition metal borides can catalyze the conversion of lithium polysulfides(Li_(2)Sn,n≥4),whereas the bond of B-S is too weak to absorb LPS.Thus BN introduced can effectively restrict the diffusion of polysulfides via strong chemisorption with LiSnLi+…N,while the rGO substrate ensures smooth electron transfer for redox reaction.Therefore,through the integrated adsorption/catalysis,the shuttle effect is suppressed,the kinetics of redox reaction is enhanced,and the capacity decay is reduced.Using CoB/BN@rGO modified PP separator,the Li-S batteries with high initial capacity(1450 mAh g^(-1)at 0.35 mA cm^(-2))and long-cycle stability(700 cycles at 1.74 mA cm^(-2)with a decay rate of 0.032%per cycle)are achieved.This work provides a novel insight for the preparation of bifunctional catalysis with integrated structure for long-life Li-S batteries. | Tianli Wu Ting Yang Jizong Zhang Xuewen Zheng Kunlin Liu Chengyang Wang Mingming Chen | 2021 | Journal of Energy Chemistry2021，30，8： | 1 |
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