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| 1 | Influence of flooding and vegetation on carbon,nitrogen,and phosphorus dynamics in the pore water of a Spartina alterniflora salt marsh显示文摘Four sites were selected in a salt marsh in the Bah' a Blanca Estuary (Argentina):(1) low marsh (flooded by the tide twice daily) vegetated by S.alterniflora;(2) non-vegetated low marsh;(3) high marsh (flooded only in spring tides) vegetated by S.alterniflora;(4) non-vegetated high marsh.The pH and Eh were measured in sediments,while dissolved nutrients (ammonium,nitrate,nitrite and phosphate) and particulate organic matter (POM) were determined in pore water.pH (6.2-8.7) was only affected by vegetation in low areas.Eh (from-300 to 250 mV) was lower at low sites than at high ones;in the latter,the values were higher in the non-vegetated sediments.The POM concentration was greater in the high marsh than in the low marsh,with no effect of vegetation.Ammonium was the most abundant nitrogen nutrient species in pore water,except in the non-vegetated high marsh where nitrate concentration was higher.All nitrogen nutrients were affected by both flooding and vegetation.Phosphate was always present in pore water at all sites throughout the year and its concentration varied within narrow limits,with no effect of flooding and greater values always at non-vegetated sites.Our results showed that the variability of the pore water composition within the marsh is greater than the temporal variation,meaning that both tidal flooding and vegetation are important in the dynamics of nutrients and organic matter in the sediment pore water. | Vanesa L.Negrin Carla V.Spetter Raúl O.Asteasuain Gerardo M.E.Perillo Jorge E.Marcovecchio | 2011 | Journal of Environmental Sciences2011，23，2： | 11 |
| 2 | Total phenolic content,in vitro antioxidant activity and chemical composition of plant extracts from semiarid Mexican region显示文摘Objective:To determine the extraction suitable conditions of total phenolic content(TPC) by heat-reflux system,antioxidant activities and HPLC characterization of the aqueous-ethanolic extracts of Jatropha dioica(J.dioica)(Dragon's blood).Flourensia cernua(F.cernua)(Tar bush).Eucalyptus camaldulensis(E.camaldulensis)(Eucalyptus) and Turnera diffusa(T.diffusa)(Damiana).Methods:TPC was evaluated by the well-known colorimetric assay using FolinCiocalteu reagent.The antioxidant activities were assayed by three methods based on scavenging of DPPH,ABTS and by lipid oxidation inhibition.The chemical composition of the extracts obtained was subject to HPLC analysis.Results:TPC in the plant extracts ranged from 2.3 to14.12 mg gallic acid equivalents/g for J.dioica and E.camaldulensis,respectively.The plant extracts of F.cernua,E.camaldulensis and T.diffusa showed similar strong antioxidant activities on scavenging of DPPH and lipid oxidation inhibition.In contrast,J.dioica extracts had lowest potential antioxidant in three assays used.HPLC assay showed the presence of several phenolic compounds in the extracts used.Conclusions:The results obtained suggest that F.cernua,E.camaldulensis and T.diffusa are potential sources to obtain bioactive phenolic compounds with high antioxidant properties which can be used in the factories as antioxidant agents or for treatments in diseases. | Jorge E.Wong-Paz Juan C.Contreras-Esquivel Raúl Rodríguez-Herrera María L.Carrillo-Inungaray Lluvia I.López Guadalupe V.Nevárez-Moorillón Cristóbal N.Aguilar | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，2： | 3 |
| 3 | miR-328 Functions as an RNA Decoy to Modulate hnRNP E2 Regulation of mRNA Translation in Leukemic Blasts显示文摘 | Anna M. Eiring Jason G. Harb Paolo Neviani Christopher Garton Joshua J. Oaks Riccardo Spizzo Shujun Liu Sebastian Schwind Ramasamy Santhanam Christopher J. Hickey Heiko Becker Jason C. Chandler Raul Andino Jorge Cortes Peter Hokland Claudia S. Huettner Ra | 2010 | Cell2010，，5： | 2 |
| 4 | Liver fat deposition and mitochondrial dysfunction in morbid obesity:An approach combining metabolomics with liver imaging and histology显示文摘AIM: To explore the usefulness of magnetic resonance imaging(MRI) and spectroscopy(MRS) for assessment of non-alcoholic fat liver disease(NAFLD) as compared with liver histological and metabolomics findings. METHODS: Patients undergoing bariatric surgery following procedures involved in laparoscopic sleeve gastrectomy were recruited as a model of obesityinduced NAFLD in an observational, prospective, singlesite, cross-sectional study with a pre-set duration of 1 year. Relevant data were obtained prospectively and surrogates for inflammation, oxidative stress and lipid and glucose metabolism were obtained through standard laboratory measurements. To provide reliable data from MRI and MRS, novel procedures were designed to limit sampling variability and other sources of error using a 1.5T Signa HDx scanner and protocols acquired from the 3D or 2D Fat SAT FIESTA prescription manager. We used our previously described 1H NMRbased metabolomics assays. Data were obtained immediately before surgery and after a 12-mo period including histology of the liver and measurement of metabolites. Values from 1H NMR spectra obtained after surgery were omitted due to technical limitations.RESULTS: MRI data showed excellent correlation with the concentration of liver triglycerides, other hepatic lipid components and the histological assessment, w h i c h e xc l u d e d t h e p r e s e n c e o f n o n-a l c o h o l i c steatohepatitis(NASH). MRI was sufficient to follow up NAFLD in obese patients undergoing bariatric surgery and data suggest usefulness in other clinical situations. The information provided by MRS replicated that obtained by MRI using the-CH3 peak(0.9 ppm), the-CH2- peak(1.3 ppm, mostly triglyceride) and the-CH=CH- peak(2.2 ppm). No patient depicted NASH. After surgery all patients significantly decreased their body weight and steatosis was virtually absent even in patients with previous severe disease. Improvement was also observed in the serum concentrations of selected variables. The most relevant findings using metabolomics indicate increased levels of triglyceride and monounsaturated fatty acids in severe steatosis but those results were accompanied by a significant depletion of diglycerides, polyunsaturated fatty acids, glucose-6-phosphate and the ATP/AMP ratio. Combined data indicated the coordinated action on mitochondrial fat oxidation and glucose transport activity and may support the consideration of NAFLD as a likely mitochondrial disease. This concept may helpto explain the dissociation between excess lipid storage in adipose tissue and NAFLD and may direct the search for plasma biomarkers and novel therapeutic strategies. A limitation of our study is that data were obtained in a relatively low number of patients.CONCLUSION: MRI is sufficient to stage NAFLD in obese patients and to assess the improvement after bariatric surgery. Other data were superfluous for this purpose. | Nahum Calvo Raúl Beltrán-Debón Esther Rodríguez-Gallego Anna Hernández-Aguilera Maria Guirro Roger Mariné-Casadó Lidón Millá Josep M Alegret Fàtima Sabench Daniel del Castillo María Vinaixa Miguelàngel Rodríguez Xavier Correig Roberto García-álvarez Javier A Menendez Jordi Camps Jorge Joven | 2015 | World Journal of Gastroenterology2015，21，24： | 2 |
| 5 | Corneal aberrations after microincision cataract surgery显示文摘 | Bassam Elkady Jorge L. Alió Dolores Ortiz Raúl Montalbán | 2008 | Journal of Cataract & Refractive Surgery2008，，1： | 1 |
| 6 | Myocardial bridge显示文摘 | Jorge RA Joerg H David RH Jr | 2005 | European Heart J2005，26，12： | 1 |
| 7 | Intravitreal bevacizumab (Avastin)for persistent new vessels in diabetic retinopathy (IBEPE study)显示文摘 | Jorge R Costa RA Calucci D | 2006 | Retina2006，26，9： | 1 |
| 8 | Intravitreal bevacizumab (Avastin)for persistent new vessels in diabetic retinopathy (IBEPE Study)显示文摘 | Jorge R Costa RA Calucci D | 2006 | Retina2006，26，9： | 1 |
| 9 | Prevalence of atherosclerotic vascular disease in cuban patients with systemic lupus erythematosus显示文摘 | Estévezdel Toro M Chico Capote A Barahona Jorge RA | 2008 | Reumatología Clínica(English Edition)2008，4，1： | 1 |
| 10 | Characterization of polyploid wheat genomic diversity using a high-density 90 000 single nucleotide polymorphism array 显示文摘 | Wang SC Debbie W Kerrie F Alexandra A Shiaoman C Bevan EH Marco M Silvio S Sara GM Luigi C Anna MM Alex W Stuart S Gary B Ralf W Joerg P International Wheat Genome Sequencing Consortium Morten L Diane M Rudi A Rudy D Gina BG Abraham K Alina RA Catherine F Jerome S Michele M Curtis P Luo MC Jan DMM Jorge D Martin G Roberto T Cindy L Ivan M Colin C Keith JE Matthew H Eduard A | 2014 | Plant Biotechnol J2014，12，： | 1 |
| 11 | Intravitreal bevacizumab (Avastin) for persistent new vessels in diabetic retinopathy (IBEPE study) 显示文摘 | Jorge R Costa RA Calucci D | 2006 | Retina2006，26，9： | 1 |
| 12 | Numerical analysis of the unsteady flow in the near-tongue region in a volute-type centrifugal pump for different operating points显示文摘 | Raúl Barrio Jorge Parrondo Eduardo Blanco | 2010 | Computers and Fluids2010，，5： | 1 |
| 13 | Aluminum-induced oxidative stress in maize 显示文摘 | Boscolo PR Menossi M Jorge RA | 2003 | Phytochemistry2003，62，： | 1 |
| 14 | 20-gauge transconjunctival pars plana vitrectomy显示文摘 | Jorge R Gomes AV Siqueira RC Costa RA Scott IU | | 0，，： | 1 |
| 15 | Holmium Laser Treatment for Low Grade, Low Stage, Noninvasive Bladder Cancer With Local Anesthesia and Early Instillation of Mitomycin C显示文摘 | Jorge Soler-Martínez Raúl Vozmediano-Chicharro Pedro Morales-Jiménez David Hernández-Alcaraz Eloy Vivas-Vargas Ildefonso Santos García-Vaquero Víctor Baena-González | 2007 | The Journal of Urology2007，，6： | 1 |
| 16 | Intravitreal bevaeizumab for ehoroidal neovascularization caused by AMD ( IBeNA Study) : results of a phase 1 dose-escalation study显示文摘 | Costa RA Jorge R Calucci D | 2006 | Invest Ophthalmol Vis Sei2006，47，10： | 1 |
| 17 | Intravitreal bevacizumab for choroidal neovascularization caused by AMD ( IBeNA Study) :results of a phase 1 dose-escalation study显示文摘 | Costa RA Jorge R Calucci D Cardillo JA Melo LA Jr Scott IU | 2006 | Invest Ophthalmol Vis Sci2006，47，10： | 1 |
| 18 | Intravitreal bevacizumab (avastin)for central and hemicentral retinal vein occlusion:IBeVO study 显示文摘 | Costa RA Jorge R Calucci D | 2007 | Retina2007，27，2： | 1 |
| 19 | Intravitreal bevacizum- ab (Avastin) for persistent new vessels in diabetic retinopathy (IBEPE study) 显示文摘 | Jorge R Costa RA Calucci D | 2006 | Retina2006，26，： | 1 |
| 20 | Evaluafior of soil quality using multiple lineal regression based on physical, chemica~ and biochemical properties 显示文摘 | Zomoza Ra ~ l Mataix-Salera Jorge Guerrero C 6 sat | 2007 | Science of the Total Environmem2007，37，12： | 1 |
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